| Lab of: | Clark W. Distelhorst, MD |
|---|---|
| Department: | Medicine-Hematology/Oncology, Pharmacology |
| Postdocs Needed: | 1 |
| Research Themes: | Apoptosis, gene regulation by glucocorticosteroid hormones, Bcl-2 mechanism of action |
| Please Contact: |
Clark W. Distelhorst, MD Professor, Medicine, Division of Hematology/Oncology, Pharmacology Associate Director, Training and Education, Case Comprehensive Cancer Center Case School of Medicine and University Hospitals of Cleveland Email: cwd@case.edu |
| Current as of: | February 12, 2008 |
| Lab of: | Mark W. Jackson, PhD |
|---|---|
| Department: | Pathology |
| Postdocs Needed: | 1 |
| Research Themes: | Common defining characteristics of human cancer cells are their insensitivity to anti-proliferative signals and their acquisition of immortality. Research in my lab utilizes in vitro models of human mammary epithelial cell (HMEC) transformation, whereby known genetic events involved in HMEC transformation are replaced by "random" genetic events, introduced using novel insertional mutagenesis lentiviruses. This approach provides new and exciting avenues to identify signaling changes that contribute to the early stages of breast hyperplasia. An appropriate candidate will have obtained a PhD recently, have a strong background in cancer cell biology or signal transduction, and be experienced with tissue culture and molecular biology techniques. Interested individuals should send their curriculum vitae and the names and addresses of three references to: |
| Please Contact: |
Mark W. Jackson, PhD Assistant Professor Department of Pathology Case Western Reserve University School of Medicine Case Comprehensive Cancer Center 2103 Cornell Road, WRB 3-134 Cleveland, OH 44106 Tel: 216/368-1276 Fax: 216/368-8919 Email: mark.w.jackson@case.edu |
| Current as of: | January 17, 2008 |
| Lab of: | Ruth A. Keri, PhD |
|---|---|
| Department: | Pharmacology, Medicine, Hematology/Oncology |
| Postdocs Needed: | 1 |
| Research Themes: | Transgenic mouse models of hormone-induced and Her-2/neu-induced breast cancer, mammary gland development, functional genomics of mammary gland development and carcinogenesis, gene expression, in vivo imaging of mammary gland tumorigenesis. |
| Please Contact: |
Ruth A. Keri, PhD Assistant Professor, Pharmacology Case School of Medicine 10900 Euclid Avenue Cleveland, Ohio 44106-4965 Tel: 216/368-3495 Email: rak5@case.edu |
| Current as of: | February 12, 2008 |
| Lab of: | Keith R. McCrae, MD |
|---|---|
| Department: | Medicine-Hematology/Oncology |
| Postdocs Needed: | 2 |
| Research Themes: | Angiogenesis, endothelial cells, endothelial progenitor cells, hemostasis |
| Please Contact: |
Keith R. McCrae, MD Associate Professor, Medicine, Division of Hematology/Oncology Case School of Medicine and University Hospitals of Cleveland Wolstein Building, 2nd Floor 2103 Cornell Road Cleveland, Ohio 44106-7284 Tel: 216/368-1175 Fax: 216/368-1166 Email: kxm71@case.edu |
| Current as of: | February 11, 2008 |
| Lab of: | Monica M. Montano, PhD |
|---|---|
| Department: | Pharmacology |
| Postdocs Needed: | 1 |
| Research Themes: | Estrogen action in hormone-responsive malignancies |
| Please Contact: |
Monica M. Montano, PhD Associate Professor, Pharmacology Case School of Medicine 10900 Euclid Avenue H.G. Wood Building, Room W307 Cleveland, Ohio 44106 Tel: 216/368-3378 or 216/368-5317 Fax: 216/368-3395 Email: mxm126@case.edu |
| Current as of: | July 11, 2007 |
| Lab of: | Shirley M. Moore, PhD, RN |
|---|---|
| Department: | Nursing |
| Postdocs Needed: | 1 |
| Research Themes: |
Vulnerable Populations with Multiple Morbidities These 2-year training programs prepare nurse scientists who are equipped to study the complex systems comprising and influencing the health of vulnerable populations with multiple morbidities. This innovative training program is based on complexity theory and emphasizes mixed methods and team approaches to conducting inquiry. With the guidance of a strong research mentorship program, fellows learn design and analytic approaches that stem from theoretical frameworks that reflect the complexity of humans and health. Our goal is to prepare a cadre of nurse scientists who are committed to the elimination of health disparities through the development of knowledge about the complex systems comprising and influencing the health of vulnerable populations. Candidates for the training programs can be enrolled in our fast-track BSN to PhD program, our traditional and summer PhD programs, and in postdoctoral training. |
| Please Contact: |
Shirley M. Moore, PhD, RN Professor and Associate Dean for Research School of Nursing Case Western Reserve University Email: shirley.moore@case.edu For more information: http://fpb.case.edu/Research/prepostdocs.shtm |
| Current as of: | February 11, 2008 |
| Lab of: | John J. Pink, PhD |
|---|---|
| Department: | General Medical Sciences - Oncology |
| Postdocs Needed: | 1 |
| Research Themes: | Research in my lab is focused on understanding mechanisms by which breast cancer cells lose their dependence on estrogens for growth. Two small calcium binding proteins, calgranulin A and calgranulin B, have been shown to be highly elevated in breast cancer cell lines selected to grow in the absence of estrogens. This finding has been supported by clinical studies showing a strong correlation between lack of estrogen receptor-alpha expression and calgranulin expression. This project will include investigations into the molecular signaling responsible for elevated calgranulin expression and the downstream effects of elevated expression of the calgranulins. Additional studies employing insertional mutagenesis to identify genes associated with the development of estrogen independence have recently been initiated and will be a significant component of the project. Complementary studies on clinical specimens will be integrated into the basic laboratory studies. As Scientific Director of the Translational Research Core Facility of the Cancer Center, I interact with numerous investigators leading various cancer based clinical trials and therefore the person filling this position will have a unique opportunity to interact with a wide variety of clinical investigators on translational research projects. Appropriate candidates should have experience in cancer cell biology, endocrinology and molecular biology, and have obtained a PhD or MD degree within the past 4 years. |
| Please Contact: |
John J. Pink, PhD Assistant Professor Department of General Medical Sciences - Oncology Case Western Reserve University School of Medicine Case Comprehensive Cancer Center 2103 Cornell Rd. Wolstein Research Building, Rm. 3529 Cleveland, OH 44106-7285 Tel (Office): 216/368-5420 Tel (Lab): 216/368-1141 Fax: 216/368-8919 Email: jrp16@case.edu |
| Current as of: | September 17, 2007 |
| Lab of: | Cheng-Kui Qu, MD, PhD |
|---|---|
| Department: | Medicine, Division of Hematology/Oncology |
| Postdocs Needed: | 1 |
| Research Themes: | Research in our laboratory is centered on the signaling mechanisms involved in normal and malignant hematopoiesis. We are particularly interested in the role of protein phosphatases in this context. One Postdoctoral position is currently available to investigate the molecular mechanisms by which gain-of-function mutations in the SHP-2 tyrosine phosphatase induce leukemia. Biochemical, genetic, and experimental hematological approaches will be undertaken in the studies. Candidates should have a Ph.D. degree and a strong background in molecular biology. Previous experience in signal transduction and experimental hematology is preferable. Interested individuals should send their curriculum vitae and the names and addresses of three references to: |
| Please Contact: |
Cheng-Kui Qu, MD, PhD Assistant Professor Department of Medicine, Division of Hematology/Oncology Case Comprehensive Cancer Center Case Western Reserve University 10900 Euclid Ave. Wolstein Bldg., Rm. 2-134 Cleveland, OH 44106 Tel: 216/368-3361 Fax: 216/368-1166 Email: cxq6@case.edu |
| Current as of: | July 30, 2007 |
| Lab of: | George R. Stark, PhD |
|---|---|
| Department: | Molecular Genetics |
| Postdocs Needed: | 1 |
| Research Themes: | Mechanisms of drug resistance |
| Please Contact: |
George R. Stark, PhD Staff, Distinguished Scientist of the Lerner Research Institute Professor of Genetics, Case Western Reserve University Department of Molecular Genetics Lerner Research Institute Email: starkg@ccf.org |
| Current as of: | January 29, 2008 |