PROTEOMICS CORE FACILITY
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Director:
Mark R. Chance, PhD
Professor, Physiology & Biophysics
mark.chance@case.edu
Co-Director:
Michael T. Kinter, PhD
Associate Professor, Cell Biology, Physiology & Biophysics
kinterm@ccf.org
Services
The overall goal of the Proteomics Core Facility is to make advanced mass spectrometry instruments, expertise, and methods for proteome analysis available to all investigators.
Services include the following:
- Protein Identification
- Characterization of post-translational modifications
- Quantitation of protein expression
- Quantitative Top-Down Proteomics using 2-D gels
- Quantitative Bottom-Up Proteomics using LC-MS
- Experimental Design for Quantitative Proteomics
- Data analysis
- Bioinformatics analysis
- Training
- Independent use
Resources
Case facility:
- Thermo-Finnigan Fourier Transform LTQ mass spectrometer
- GE/Amersham 2-D gel DIGE system
- Two Applied Biosystems Q-star mass spectrometers
- Thermo-Finnigan DECA XP-Plus and LTQ instruments
- Beckman Biomek FX robotic liquid handling systems
- prOTOF 2000 MALDI Mass Spectrometer
Lerner Research Institute facility:
- Three capillary column HPLC-electrospray ionization-tandem mass spectrometry systems
- One MALDI-TOF system (TofSpec 2E)
- ThermoFinnigan LCQ-deca
- ThermoFinnigan LTQ
- Micromass Q-ToFmicro
Further Information
Case Western Reserve University
Center for Proteomics and Mass Spectrometry
http://casemed.case.edu/proteomics/
Cleveland Clinic Lerner Research Institute
Proteomics Laboratory
http://www.lerner.ccf.org/services/mass_spec/
Contact for Information
| CASE FACILITY: | LRI FACILITY: | ||
| Location: | Case BRB 9th floor | Location: | LRI Room NN1-25 |
| Director: | Mark R. Chance, PhD | Co-Director: | Michael T. Kinter, PhD |
| Phone: | 216/368-4406 | Phone: | 216/444-7170 |
| E-mail: | mark.chance@case.edu | E-mail: | kinterm@ccf.org |
| General Contact: | |||
| Phone: | 216/368-1490 | ||
| E-mail: | proteomics@case.edu | ||