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Case Comprehensive Cancer Center

Cytometry & Imaging Microscopy

Cytometry & Imaging Microscopy

This core provides access to instrumentation to perform cell based assays and cell sorting. Trained users schedule time on instruments, then come to the facility and run their own samples. Core staff are on-site to help if difficulties arise. In special cases, samples can be run by Core staff by prior arrangement. The core operates on a cost recovery basis. Prior to access, users need to supply a valid account that will be charged at the end of the month of access.

Sometimes it is more expedient or necessary to use other available Cytometry and Microscopy cores. We fully support this and cooperate with facilities for cytometry - Center for AIDS ResearchInfectious DiseasesLRI Flow Cytometry Core, and microscopy - CWRU SOM Neurosciences and the Lerner Research Institute.


First time access:
Contact Mike Sramkoski ( He will arrange orientation and training.

Experienced users:
Workflow begins by scheduling time on the appropriate instrument using an online scheduler (; show up on time, then operate the instrument (run samples and acquire data). To contact Core staff with questions or as an alternative to the scheduler send an email to


Please remember to acknowledge the valuable services provided by Cancer Center Core Facilities in your research papers and publications:
"This research was supported by the Cytometry & Imaging Microscopy Core Facility of the Case Comprehensive Cancer Center (P30CA043703)."

Contact for Information

For scheduling and other operational question

Core Staff 216.368.5267
For introduction to the facility and initial scheduling  
Mike Sramkoski 216.368.1021
For support in the form of letters, written text (grants and papers)  
James Jacobberger 216.368.4645
For consultation  
Mike Sramkoski 216.368.1021
Additional core facility expert(s) will be invited to consultation based upon project focus:
James Jacobberger: cell biology, cell kinetics, cell signaling, multiparametric analysis
Howard Meyerson: clinical immunophenotyping and related assays; imaging flow cytometry
Scott Sieg: immunology assays (cytokine ELISA, ELISPOT; AutoMACS, immunophenotyping)
Brian Grimberg: global health, malaria, parasitic diseases
Tammy Stefan: expert staff; laser scanning cytometry and imaging flow cytometry
Amy Graham: expert staff; imaging flow cytometry


James W. Jacobberger, PhD
Professor, General Medical Sciences (Oncology)


Mike Sramkoski, BS MT(ASCP)H

Online Scheduling Available for Experienced Users

Experienced users may schedule time on the appropriate instrument using the Ca-MiMi online scheduler.