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Ohio Brain Tumor Working Group

Ohio Brain Tumor Working Group

The purpose of this group is to plan for the formation of the Ohio Brain Tumor Specialized Program of Research Excellence (SPORE) .


Steven Rosenfeld, MD, PhD
Peter Houghton, PhD
Jill Barnholtz-Sloan, PhD

Major Participating Institutions

Case Western Reserve University (CWRU)
University Hospitals Cleveland Medical Center (UHCMC)
Cleveland Clinic
Ohio State University (OSU)
Nationwide Children's Hospital
Greehey Children's Cancer Research Institute
Cincinnati Children's Hospital
Emory University 
University of Minnesota (UMN)

Planned Structure of Ohio Brain Tumor SPORE

Administrative Core: Steven Rosenfeld, MD, PhD; Peter Houghton, PhD; Jill Barnholtz-Sloan, PhD; Yingli Wolinsky, PhD, MBA

Biospecimen Core: Nilsa Ramirez, MD

Biostatistics & Informatics Core: Jill Barnholtz-Sloan, PhD; Michael Kattan, PhD

Career Enhancement Program: Nathan Berger, MD

Developmental Research Program: Nathan Berger, MD

Scientific Projects

Project 1: Targeting Intratumoral Heterogeneity by Integrating Combination Therapies and Single Cell Analysis
Justin Lathia, PhD (CWRU/Cleveland Clinic)
Monica Venere, PhD (OSU)
George Stark, PhD (CWRU/Cleveland Clinic)
Manmeet Ahluwalia, MD (CWRU/Cleveland Clinic)
Andrew Sloan, MD (CWRU/UHCMC)
Project 2: Utility of Imaging and Pathology Analytics for Clinical Decision Support for Glioblastoma
Jill Barnholtz-Sloan, PhD (CWRU)
Lee Cooper, PhD (Emory)
Daniel Brat, MD, PhD (Emory)
Project 3: Targeting Kif11 to Treat Glioblastoma Invasion and Proliferation
Steven Rosenfeld, MD, PhD (CWRU/Cleveland Clinic)
William Elmquist, PharmD, PhD (UMN)
Manmeet Ahluwalia, MD (CWRU/Cleveland Clinic)
David Peereboom, MD (CWRU/Cleveland Clinic)
Andrew Sloan, MD (CWRU/UHCMC)

Project 4: Developing BRAF-Specific Therapies for Low-Grade Astrocytoma
Peter Houghton, PhD (Greehey)
Maryam Fouladi, MD (Cincinnati)