GU Malignancies

Program Leader

Brian I. Rini, MD

Brian I. Rini, MD
Professor, Solid Tumor Oncology
rinib2@ccf.org

Bing-Cheng Wang, PhD

Bing-Cheng Wang, PhD
Professor, Medicine-Nephrology
bxw14@case.edu


Program Themes


  • Molecular basis of prostate and renal cancer development and progression
  • Novel biomarkers and tumor-based targets for chemoprevention and treatment
  • Stromal and host factors in prostate and renal cancer including inflammation, immunomodulation and angiogenesis
  • Translational research and novel investigator-initiated clinical trials

Program Information

The overarching goal of the GU Malignancies Program is to explore fundamental biologic pathways of critical importance to the development and progression of prostate and renal cancer and to foster translational, investigator-initiated clinical trials to advance therapeutic options.

To provide additional structure and promote cohesion within the larger Program, investigators have been further organized around two scientific focus areas:

  • Prostate Cancer - includes genetic susceptibility and molecular basis, chemoprevention, molecular biomarkers of prognosis and therapeutic targeting of the IGF and PI3K/Akt/mTOR axis
  • Renal Cancer - includes molecular and clinical biomarkers of prognosis, response and resistance; immunomodulatory effects of treatment, and therapeutic targeting of angiogenesis and the PI3K/Akt/mTOR axis

Program Members

Tatiana V. Byzova, PhD
Assistant Professor, Molecular Cardiology
byzovat@ccf.org

Steven C. Campbell, MD, PhD
Professor, Urology
campbes3@ccf.org

Edward E. Cherullo, MD
Associate Professor, Urology
edward.cherullo@UHhospitals.org

Jay P. Ciezki, MD
Associate Professor, Radiation Oncology
ciezkij@ccf.org

Matthew M. Cooney, MD
Assistant Professor, Medicine-Hematology/Oncology
matthew.cooney@UHhospitals.org

David Danielpour, PhD
Professor, General Medical Sciences (Oncology)
dxd49@case.edu

Joseph A. DiDonato, PhD
Assistant Professor, Cancer Biology
didonaj@ccf.org

Robert Dreicer, MD
Professor, Solid Tumor Oncology
dreicer@ccf.org

James H. Finke, PhD
Professor, Immunology
finkej@ccf.org

Jorge A. Garcia, MD
Assistant Professor, Solid Tumor Oncology
garciaj4@ccf.org

Brian R. Gastman, MD
Associate Professor, Plastic Surgery and Immunology
gastmab@ccf.org

Timothy D. Gilligan, MD
Associate Professor, Solid Tumor Oncology
gilligt@ccf.org

Sanjay Gupta, PhD
Professor, Urology
sanjay.gupta@case.edu

Warren D.W. Heston, PhD
Professor, Cancer Biology, Urology
hestonw@ccf.org

Christopher J. Hoimes, DO
Assistant Professor, Medicine-Hematology/Oncology
christopher.hoimes@case.edu

Hui (Grace) Jin, PhD
Instructor, Pharmacology
hui.jin@case.edu

Bethany Kerr, PhD
Assistant Professor, Molecular Cardiology
kerrb2@ccf.org

Eric A. Klein, MD
Professor, Urology
kleine@ccf.org

Gregory T. MacLennan, MD
Professor, Pathology
gregory.maclennan@UHhospitals.org

Cristina Magi-Galluzzi, MD, PhD
Associate Professor, Anatomic Pathology
magic@ccf.org

Carvell Nguyen, MD, PhD
Assistant Professor, Surgery-Urology
cnguyen4@metrohealth.org

Lee E. Ponsky, MD
Associate Professor, Urology
lee.ponsky@UHhospitals.org

Brian I. Rini, MD
Professor, Solid Tumor Oncology
rinib2@ccf.org

Nima Sharifi, MD
Associate Professor, Cancer Biology
sharifn@ccf.org

Robert H. Silverman, PhD
Professor, Cancer Biology
silverr@ccf.org

Andrew J. Stephenson, MD
Associate Professor, Urology
stephea2@ccf.org

Charles S. Tannenbaum, PhD
Assistant Professor, Immunology
tannenc@ccf.org

Angela H. Ting, PhD
Assistant Professor, Molecular Medicine
tinga@ccf.org

Bing-Cheng Wang, PhD
Professor, Medicine-Nephrology
bxw14@case.edu

Ping Xia, PhD
Professor, Radiation Oncology
xiap@ccf.org

Hui Zhu, MD
Assistant Professor, Urology
hui.zhu@UHhospitals.org