Ohio Brain Tumor Working Group

The purpose of this group is to plan for the formation of the Ohio Brain Tumor Specialized Program of Research Excellence (SPORE) .

Co-Leaders:

Steven Rosenfeld, MD, PhD
Peter Houghton, PhD
Jill Barnholtz-Sloan, PhD

Major Participating Institutions

Case Western Reserve University (CWRU)
University Hospitals Case Medical Center (UHCMC)
Cleveland Clinic
Nationwide Children's Hospital
Ohio State University (OSU)
Cincinnati Children's Hospital

Planned Structure of Ohio Brain Tumor SPORE

Administrative Core: Steven Rosenfeld, MD, PhD; Peter Houghton, PhD; Jill Barnholtz-Sloan, PhD; Yingli Wolinsky, PhD, MBA

Biospecimen/Tissue Core: Nilsa Rameriz, MD

Biostatistics Core: Jill Barnholtz-Sloan, PhD; Michael Kattan, PhD

Career Development Program: Nathan Berger, MD

Developmental Research Program: Nathan Berger, MD

Scientific Projects

Project 1: Reducing Communication between Cancer Stem Cells as an Anti-Glioblastoma Therapy
Justin Lathia, PhD (CWRU/Cleveland Clinic)
Manmeet Ahluwalia, MD (CWRU/Cleveland Clinic)

Project 2: Targeting EphA2 in Glioblastoma with Novel Small Molecule Agonists
Bingcheng Wang, PhD (CWRU/MetroHealth)
Dolores Hambardzumyan, PhD (CWRU/Cleveland Clinic)
David Peereboom, MD (CWRU/Cleveland Clinic)
Andrew Sloan, MD (CWRU/UHCMC)

Project 3: Targeting the Microglial Cell Response in Glioblastoma
Candece Gladson, MD (CWRU/Cleveland Clinic)
Manmeet Ahluwalia, MD (CWRU/Cleveland Clinic)

Project 4: Developing BRAF-Specific Therapies for Low-Grade Astrocytoma
Peter Houghton, PhD (Nationwide)
Maryam Fouladi, MD (Cincinnati)

Joint Publications