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FUNDING AGENCIES:

BASIC SCIENCE OF CANCER FOCUS GROUPS

CANCER VASCULAR BIOLOGY AND ANGIOGENESIS

Leader: Keith R. McCrae, MD
Professor, Medicine-Hematology/Oncology
keith.mccrae@case.edu
 
Roy L. Silverstein, MD
Professor, Cell Biology
silverr2@ccf.org

SUMMARY

The goals of the Cancer Vascular Biology and Angiogenesis focus group include a) developing coordinated efforts focused on understanding the basic biology of abnormal vascular development and function in cancer, b) identifying potential agents with anti-angiogenic activity for potential use in cancer, c) understanding the molecular mechanisms by which such agents inhibit the development and/or function of the tumor vasculature, d) identifying novel vascular targets for development of angiogenesis inhibitors, e) supporting early phase clinical trials through mechanistic translational research, and the development biomarkers as surrogates for drug efficacy.

MEMBERS

Josephine C. Adams, PhD
Professor, Cell Biology
adamsj@ccf.org

Eben Alsberg, PhD
Assistant Professor, Biomedical Engineering
eben.alsberg@case.edu

Bela Anand-Apte, MD, PhD
Associate Professor, Ophthalmology/Cell Biology
anandab@ccf.org

Suneel S. Apte, MBBS, DPhil
Associate Professor, Biomedical Engineering
aptes@bme.ri.ccf.org

Joseph Baar, MD, PhD
Associate Professor, Medicine-Hematology/Oncology
joseph.baar@UHhospitals.org

Harihara Baskaran, PhD
Associate Professor, Chemical Engineering
hxb35@case.edu

Tatiana V. Byzova, PhD
Assistant Professor, Molecular Cardiology
byzovat@ccf.org

Paul E. DiCorleto, PhD
Professor, Cell Biology, Physiology & Biophysics
dicorlp@ccf.org

Afshin Dowlati, MD
Associate Professor, Medicine-Hematology/Oncology
axd44@case.edu

Maria Febbraio, PhD
Associate Professor, Cell Biology
febbram@ccf.org

Paul L. Fox, PhD
Professor, Cell Biology
foxp@ccf.org

Hung-Ying Kao, PhD
Associate Professor, Biochemistry
hxk43@case.edu

Zhenghong Lee, PhD
Associate Professor, Radiology, Biomedical Engineering
zxl11@case.edu

Keith R. McCrae, MD
Professor, Medicine-Hematology/Oncology
keith.mccrae@case.edu

Patricia Parsons-Wingerter, PhD
Adjunct Staff, Cell Biology, John Glenn Research Center, NASA
patricia.parsons@grc.nasa.gov

Edward F. Plow, PhD
Professor, Molecular Cardiology
plowe@ccf.org

Diana L. Ramirez-Bergeron, PhD
Assistant Professor, Medicine-Cardiology
diana.ramirez@case.edu

Brian I. Rini, MD
Associate Professor, Hematology & Medical Oncology
rinib2@ccf.org

Takao Sakai, MD, PhD
Assistant Professor, Biomedical Engineering
sakait@ccf.org

Alvin H. Schmaier, MD
Professor, Medicine-Hematology/Oncology
alvin.schmaier@case.edu

Roy L. Silverstein, MD
Professor, Cell Biology
silverr2@ccf.org

Daniel I. Simon, MD
Professor, Medicine-Cardiology
daniel.simon@UHhospitals.org

Horst von Recum, PhD
Assistant Professor, Biomedical Engineering
hav1@case.edu

Qing K. Wang, PhD, MBA
Associate Professor, Molecular Cardiology
wangq2@ccf.org

David L. Wilson, PhD
Professor, Biomedical Engineering
dlw@case.edu


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