February 24, 2014
MESSAGE FROM THE DIRECTOR
Stan Gerson, MD
Food Safety for Cancer Patients
We all worry about food safety issues in cancer patients. Issues relate to proper advice about food preferences, treatment food interactions, and food restrictions in immunosuppressive patients. An additional topic of importance is how to counsel patients in the setting of food recalls, and the real potential that cancer patients are at special risk.
The USDA Office of Public Affairs and Consumer Education recently collaborated with the FDA to prepare a publication on Food Safety for Cancer Patients. The publication is free, and can be either downloaded from the FDA website or ordered via email from email@example.com.
PRESIDENT'S CANCER PANEL UPDATE
HPV Vaccination: A Significant Opportunity for Cancer Prevention
The following piece was written by Dr. Susan A. Flocke, Director of the Behavioral Measurement Core Facility and co-Leader of the Cancer Prevention, Control and Population Research Program of the Case Comprehensive Cancer Center. She is also Associate Professor of Family Medicine and Epidemiology & Biostatistics at CWRU.
The President's Cancer Panel monitors progress of the National Cancer Program, identifies topics of high importance to the nation, and recommends action to address identfied issues. Earlier this month, the Panel highlighted human papillomavirus (HPV) vaccines as an effective but under-used intervention to prevent cancers1.
Letters from the Panel were sent to multiple stakeholder organizations and to the President of the United States urging action to increase the uptake of HPV vaccination, especially in adolescents. The primary message of the calls to action is that HPV vaccination is cancer prevention and that the HPV vaccination is safe, effective, and especially important given the high prevalence of HPV.
In the United States, about 79 million people are currently infected with HPV and about 14 million become newly infected each year. More than 26,000 cancers each year are attributed to HPV, with cervical cancer in women accounting for most of these cases (10,300), followed by oropharyngeal cancer in men (6,700)2.
Currently, the Centers for Disease Control and Prevention (CDC) recommends HPV vaccination for girls and boys at ages 11 and 12. For those who were not vaccinated at age 11-12, HPV vaccination is recommended for females ages 13 through 26 and males ages 13 through 21.
Cervarix and Gardasil are two HPV vaccines that are available for girls to protect against the HPV types that cause most cervical and anal cancers. Gardasil also protects against the HPV types that cause most genital warts; Gardasil is the only vaccine approved for boys. Both brands of HPV vaccine are given in three doses over six months.
Currently, only about 33% of US adolescent girls complete HPV vaccination3. Completion rates among boys is even lower at 7%. Unlike other types of vaccinations like Tdap (tetanus toxoid, reduced diphtheria toxoid and acellular pertussis) and MenACWY (meningococcal conjugate) that have improved in coverage since 2006, HPV uptake has been poor with coverage rates dropping from 2011 to 20123.
Factors associated with lack of uptake include lack of provider recommendation4,5 and parental concerns about side effects or potential harm to the child from the vaccine4.
Specific suggestions from the President's Cancer Panel1 for accelerating HPV vaccine uptake include:
Clinicians can immediately act by providing a consistent and focused message about HPV vaccination to age-eligible patients and parents. The American Academy of Family Physicians recently summarized what clinicians can tell parents when they express concerns about the vaccine for their child:
Increasing HPV vaccine uptake is a cancer prevention and public health priority. Action is required to change parental perception of the vaccine, increase its usage, prevent further spread of HPV.
2US Department of Health and Human Services, Centers for Disease Control and Prevention. (2013). Human papillomavirus (HPV)-associated cancers.
3US Department of Health and Human Services, Centers for Disease Control and Prevention. (2013). National and State Vaccination Coverage Among Adolescents Aged 13-17 Years –United States, 2012. Morbidity and Mortality Weekly Report 62(34):685-693.
4Kester, LM, Zimet, GD, Fortenberry, JD, Kahn, JA, & Shew, ML. (2013). A National Study of HPV Vaccination of Adolescent Girls: Rates, Predictors, and Reasons for Non-Vaccination. Matern Child Health J, 17:879-885.
5Dorell, C, Yankey, D, & Strasser, S. (2011). Parent-reported reasons for nonreceipt of recommended adolescent vaccinations, National Immunization Survey–Teen, 2009. Clinical Pediatrics, 50(12), 1116-1124.
CASE CCC IN THE NEWS
Teen Optimistic Heading into Fight with Cancer
Head & Neck Cancer Research Findings: Longer survival for HPV-positive cancers, the benefits of outpatient care
Cleveland Clinic Part of Study Testing New Imaging Technology to Help Avoid Unneeded Breast Biopsy
FDA approves Imbruvica for CLL
Molecular Imaging Probes Detect Brain Tumors and Dispersed Cells
SAVE THE DATE
Inaugural Case Comprehensive Cancer Center Academic Drug Development Seminar
The Inaugural Case Comprehensive Cancer Center Academic Drug Development Seminar, will be held on February 26 at 4pm in the Global Cardiovascular Innovation Center, 10000 Cedar Avenue. This first seminar will feature a presentation by Dr. Goutham Narla, Assistant Professor, Medicine and Transformative Molecular Medicine at CWRU/UH, on Drugging the Undruggable: Small Molecule Activators of Tumor Suppressor Genes.
As part of the Case CCC Developmental Therapeutics Program, this series will gather clinicians, scientists, medical chemists, computer-aided drug designers, screeners, and commercialization personnel in the same room as a stimulating presentation so that all attendees can learn and benefit from the sparked interaction.
Retreat: Engaging in Cultural Competence through Awareness, Knowledge and Action
Please mark your calendars for Thursday, March 13 from 2-5 pm to join the Case Comprehensive Cancer Center and the Case Center for Reducing Health Disparities as they explore issues related to cultural competence. Extend your knowledge and raise your awareness about the dynamic variety of people and communities the Case CCC serves. This retreat will feature a keynote address by Dr. Sonja Harris-Haywood, and will provide perspective on the growing need to be culturally competent and facilitate the impact of cultural beliefs within the health care setting, specifically in research.
The retreat is intended for investigators, research nurses, regulatory coordinators, outreach and training and education personnel. Pre-registration by Friday, March 7 is required. Please direct any questions to Katarzyna Karelus at 216.844.4176 or firstname.lastname@example.org.
Lung Cancer Research Foundation
The Lung Cancer Research Foundation is accepting applications for its funding program. The Foundation funds research it believes will make major contributions toward better treatments, screening, and prevention of lung cancer.
Genetics Student Seminar
Pathology Research Seminar Series
Genomic Medicine Institute Seminar Series
Pathology Thesis Defense
Case CCC Breast Program Focus Group meeting
Physiology & Biophysics Seminar
Radiation Oncology Grand Rounds
Molecular Genetics Departmental Seminar
Cellular and Molecular Medicine Seminar Series
Immunology Seminar Series
Cancer Biology Seminar
Hematology and Oncology Division Research Conference
Pathology Grand Rounds
Neurosciences Guest Speaker Seminar
Genetics and Genome Sciences Seminar
Molecular Cardiology Faculty Seminar Series
Cancer Center Academic Drug Development Seminar
Frontiers in Biological Sciences Lecture Series
Molecular Genetics Midterm Review Seminar
Immunology Journal Club
Molecular Biology and Microbiology Seminar
Prostate Cancer Symposium
Hematology/Oncology Fellows Conference/Curriculum Series
Taussig Cancer Institute Grand Rounds
Cellular and Molecular Medicine Seminar Series
Cancer Center Seminar Series, co-sponsored by the Dept. of Biochemistry
Cancer Center Research in Progress
UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS
Screening for Cancer in Women: 2014
Case CCC Annual Scientific Retreat
ADDITIONAL UPCOMING SEMINARS & EVENTS
1st Annual Multidisciplinary Colorectal Oncology Course
PREVIOUSLY ANNOUNCED OPPORTUNITIES
Dan David Prize Scholarships
Sta Op Tegen Kanker Dream Team Translational Cancer Research Grant
NIH BULLETIN – Notices and Funding Opportunities
Request For Information (RFI): Input on The Development of A Novel Drug Screening Program to Be Conducted at NCI's Drug Development Laboratories at The Frederick National Laboratory for Cancer Research (NOT-CA-14-032)
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