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Case Comprehensive Cancer Center Newsletter

September 3, 2013

CASE CCC IN THE NEWS

Cleveland Clinic Researcher Discovers Genetic Mutation in Deadly Form of Prostate Cancer
The Plain Dealer - Aug 29, 2013
A Cleveland Clinic researcher has discovered a genetic mutation in one of the deadliest forms of prostate cancer..."When we made the initial observation [of the mutation], we quickly realized what it could mean," said Dr. Nima Sharifi, who led the work at the Clinic's Lerner Research Institute. It took an additional three years to identify the mechanism by which the resistance happens, he said.

University Hospitals, One of the First in the World to Use PET/MRI, Gives Technology a Good Review
The Plain Dealer - Aug 29, 2013
Based on the results of 116 cancer patients, all of whom had PET/MRI and PET/CT scans, they found that PET/MRI not only provided a more accurate detection of the disease and areas where it had spread, but in some cancer types it distinguished more effectively malignant tumors from benign ones...Based on scans taken after just a couple doses of chemotherapy, oncologists are also starting to be able to predict if a patient will respond well to treatment, said Dr. Pablo Ros, chairman of radiology at UH Case.

Second-line Chemotherapy Superior to Erlotinib for EGFR Wild-type NSCLC
HemOnc Today - Aug 21, 2013
Study finds chemotherapy the best treatment option for patients with advanced non-small cell lung cancer who have wild-type EGFR tumors. Dr. Nathan Pennell shares his perspective.


ANNOUNCEMENTS

Stan Gerson Awarded Top Honor at CWRU for His Academic Achievements and Collaborative Leadership

gersonCancer Center Director Dr. Stan Gerson was honored at convocation last week when he was named Distinguished University Professor. The title is the highest honor that can be awarded to university faculty, and recognizes the outstanding contributions of full-time, tenured professors with exceptional academic records of research, scholarship, teaching and service. In receiving this title, Dr. Gerson joins the ranks of other outstanding faculty researchers, including Drs. Nathan Berger and Richard Hanson, who served as scientific mentors to him early in his career.

Database of Potential Student Lab Assistants

The Cancer Center has a database of undergraduate and graduate students who are interested in working in cancer research labs or are doing rotations for the Biomedical Sciences Training Program (BSTP). If you are interested in hosting a student volunteer, employee, or rotation, please contact Lyn Haselton at lmh92@case.edu. We appreciate your support and interest in training the next generation of cancer researchers!


MARK YOUR CALENDARS

Call for Abstracts: Graft-versus-Host Disease (GvHD) National Symposium

Registration is open for the Graft-versus-Host Disease (GvHD) National Symposium, Friday, November 1 at the Embassy Suites Cleveland. This conference is intended to raise awareness about the signs and symptoms of GvHD, review cutting edge approaches to prevention and treatment, and highlight and promote research to further our understanding of its cause. The symposium will have two tracks: a scientifically rigorous one for physicians and practitioners, and a survivor track that will focus on challenges faced by BMT recipients and their families. CME credit is available.

This symposium will also feature a poster session. Abstracts should be submitted no later than Friday, September 27 at 5 pm to lmh92@case.edu. Abstracts will be published in a booklet or the syllabus, which will be given to all participants. Prizes will be awarded. The registration fee for invited presenters is complimentary, but advance registration is required.


FUNDING OPPORTUNITIES

Pancreatic Cancer Action Network-AACR Grants

The Pancreatic Action Network and the American Association for Cancer Research (AACR) have partnered to offer the following funding opportunities:

  • The Pancreatic Cancer Action Network-AACR Innovative Grants represent a joint effort to promote and support innovative pancreatic cancer research. They aim to spur creative and cutting-edge ideas and approaches in pancreatic cancer research, including those successful in other areas of cancer that have justifiable promise for pancreatic cancer. The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.
    LOI Deadline: October 7
    Application Deadline: January 15, 2014
  • The goal of the Pancreatic Cancer Action Network-AACR Research Acceleration Network (RAN) Grants is to provide funding and strategic assistance to research projects with the potential to double survival for pancreatic cancer by the year 2020. These projects must be implemented by a multi-institutional team and include a clinical component with an endpoint relevant to improving the detection or treatment of pancreatic cancer.
    LOI Deadline: October 7
    Application Deadline: January 15, 2014
  • The Pancreatic Cancer Action Network-AACR Career Development Awards represent a joint effort to encourage and support junior faculty who are in the first five years of a faculty appointment (at the start of the grant term) to conduct pancreatic cancer research and establish successful career paths in this field. The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.
    Application Deadline: October 29
Alex's Lemonade Stand Foundation

Alex's Lemonade Stand Foundation (ALSF) is accepting applications for the following grant opportunities:

  • The purpose of the Reach Award is to advance ALSF's mission to find cures and better treatments for childhood cancers by providing support to move hypothesis-driven research into the clinic. Significant barriers exist that impede the translation of innovative and important ideas to the clinic. The Reach Award seeks to remove one of these barriers by providing support for important pre-clinical projects that are necessary to move a study from the pre-clinical arena into a clinical trial. Thus, the goal of this award is to support selected "late translational" studies needed to ultimately initiate a clinical trial. Preference will be given to those research projects which, if funded, will result in the initiation of a clinical trial within two to three years.
    Deadline: October 15
  • Epidemiology Grants are expected to provide funds that will support investigators pursuing epidemiological research aimed at improving our understanding of childhood cancer. This grant mechanism is designed to support the research that focuses on 1) the epidemiology, early detection or prevention of childhood cancer or 2) comparative effectiveness and outcomes research related to detection, prevention and treatment.
    Deadline: December 16

EVENTS

calendar

September 2

Happy Labor Day!


September 3

Immunology Seminar Series
Jose A. Cancelas Perez, MD, PhD
Deputy Director, Hoxworth Blood Center
Professor, Pediatrics
University of Cincinnati
Topic: BCR/ABL Leukemia: New Targets for Intervention
12 pm WRB 1-413

Pharmacology Seminar
Thomas McIntyre, PhD
Staff, Cellular and Molecular Medicine
Cleveland Clinic
Topic: Oxidized Phospholipids Connect Mitochondria to Apoptosis
12 pm Webster Conference Room, W331

DNA Damage/Repair Focus Group
Alex Almasan, PhD
Professor, Cancer Biology, Radiation Oncology
CWRU/Cleveland Clinic
Topic: Role of Autophagy and TMPRSS2-ERG in NHEJ DNA Repair
4 pm WRB 3-136


September 4

Hematology and Oncology Research Conference Special Presentation
Joseph Baar, MD, PhD
Associate Professor, Div. of Hem/Onc
CWRU/UH
Topic: Introduction to Early Stage/Local Breast Cancer
8 am Lerner B-151

Pathology Grand Rounds
Joseph E. Willis, MD
Vice Chair for Clinical Affairs and Associate Professor, Pathology
CWRU/UH
Topic: Molecular Testing of Colorectal Cancer- Helping Patients From Multiple Approaches
8 am Pathology Amphitheatre

Development and Differentiation: from Structure to Function
Elaine Fuchs, PhD
Rebecca C. Lancefield Professor in Mammalian Cell Biology
Howard Hughes Medical Institute
Rockefeller University
Topic: Developing and Maintaining a Lifelong Passion for Science
11 am WRB 1-413

Immunology Students/Fellows Research in Progress Seminar Series
Laura Davison
Graduate Student, Jorgensen lab, Immunology
Cleveland Clinic
Topic: The Role of IDO and the Effects of 1-MT on Disease Development in B6.Nba2 Lupus-Prone Mice
12 pm NC1-202 Cleveland Clinic

Development and Differentiation: from Structure to Function
Elaine Fuchs, PhD
Rebecca C. Lancefield Professor in Mammalian Cell Biology
Howard Hughes Medical Institute
Rockefeller University
Topic: Epithelial Stem Cells in Homeostasis, Wound-repair and Cancer
4 pm WRB 1-413


September 5

Immunology Journal Club
Jenny Johnson
PhD Candidate, Cobb lab, Pathology
CWRU/UH
Topic: Shp1 Regulates T Cell Homeostasis by Limiting IL-4 Signals
12 pm WRB 5-136


September 6

Hematology/Oncology Fellows Conference/Curriculum Series
Topic: TBD
8 am Wearn 137/Breen Conference Rm

Taussig Cancer Institute Grand Rounds
Michael Keng, MD
Cleveland Clinic
Topic: The Cleveland Clinic Febrile Neutropenia Experience
8 am R3/002-003 Cleveland Clinic

Cellular and Molecular Medicine Seminar Series
Babak Razani, MD, PhD
Assistant Professor, Medicine-Cardiovascular
Washington University
Topic: The Autophagy-Lysosome System in Macrophages: A Nexus for Lipid Metabolism and Inflammation in Atherosclerosis
10 am NC1-202 Cleveland Clinic

BME Guest Speaker
Damir Janigro, PhD
Professor, Cell Biology
Cleveland Clinic
Topic: The Blood-brain Barrier in Health & Disease
11 am NA1-142 Cleveland Clinic

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

 

ADDITIONAL UPCOMING SEMINARS & EVENTS

 

New Directions in Melanoma and Non-Melanoma Skin Cancers
October 18
Holiday Inn–Cleveland South

National GvHD Health Symposium
November 1
Embassy Suites Cleveland-Rockside
Details


PREVIOUSLY ANNOUNCED OPPORTUNITIES

Burroughs Wellcome Fund Career Awards at the Scientific Interface
Deadline: September 3

Susan G. Komen Career Catalyst Research Grants – Basic and Translational Research
Pre-Application Deadline: September 5
Full Application Deadline: December 5

Susan G. Komen Career Catalyst Research Grants – Clinical Research
Pre-Application Deadline: September 5
Full Application Deadline: December 5

Susan G. Komen Postdoctoral Fellowship Grants – Basic and Translational Research
Pre-Application Deadline: September 5
Full Application Deadline: December 5

Susan G. Komen Postdoctoral Fellowship Grants – Clinical Research
Pre-Application Deadline: September 5
Full Application Deadline: December 5

Susan G. Komen Graduate Training in Disparities Research (GTDR)
Pre-Application Deadline: September 5
Full Application Deadline: December 5

AACR-CRI Lloyd J. Old Award in Cancer Immunology
Nomination Deadline: September 6

Pezcoller Foundation–AACR International Award for Cancer Research
Nomination Deadline: September 12

Avon Safety Net Program
LOI Deadline: September 12
Application Deadline: October 24

Alex's Lemonade Stand Foundation 'A' Award
Deadline: September 16

PCRP Health Disparity Research Award
LOI Deadline: September 18
Application Deadline: October 9

PCRP Clinical Consortium Award
LOI Deadline: September 18
Application Deadline: October 9

PCRP Prostate Cancer Pathology Resource Network (PCPRN or Network) Award
LOI Deadline: September 18
Application Deadline: October 9

PCRP Population Science Impact Award
LOI Deadline: September 18
Application Deadline: October 9

AACR-American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention
Nomination Deadline: September 19

AACR Princess Takamatsu Memorial Lectureship
Nomination Deadline: September 19

AACR Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research
Nomination Deadline: September 26

Szent-Györgyi Prize for Progress in Cancer Research
Deadline: September 30

Burroughs Wellcome Fund Career Awards for Medical Scientists
Deadline: October 1

Leukemia & Lymphoma Society Scholar
LOI Deadline: October 1
Application Deadline: October 15

Leukemia & Lymphoma Society Scholar in Clinical Research
LOI Deadline: October 1
Application Deadline: October 15

Leukemia & Lymphoma Society Special Fellow
LOI Deadline: October 1
Application Deadline: October 15

Leukemia & Lymphoma Society Special Fellow in Clinical Research
LOI Deadline: October 1
Application Deadline: October 15

Leukemia & Lymphoma Society Fellow
LOI Deadline: October 1
Application Deadline: October 15

AACR Award for Outstanding Achievement in Chemistry in Cancer Research
Nomination Deadline: October 3

AACR-Minorities in Cancer Research Jane Cooke Wright Lectureship
Nomination Deadline: October 3

AACR-Women in Cancer Research Charlotte Friend Memorial Lectureship
Nomination Deadline: October 3

Melanoma Research Alliance Team Science Awards
LOI Deadline: October 7

BCRP Breakthrough Award
Pre-Application Deadline: October 8
Application Deadline: January 15, 2014

AACR Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research
Nomination Deadline: October 10

AACR Richard and Hinda Rosenthal Memorial Award
Nomination Deadline: October 10

RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families
Deadline: October 15

AACR G.H.A. Clowes Memorial Award
Nomination Deadline: October 17

Foundation for Women's Cancer Claudia Cohen Research Foundation Prize for Outstanding Gynecologic Cancer Researcher
Deadline: October 23

Foundation for Women's Cancer Dr. John L. Lewis, Jr./William F. O'Connor Foundation Research Prize
Deadline: October 23

Foundation for Women's Cancer Perlman Family CARE Lynch Syndrome Research Prize
Deadline: October 23

Fourth Annual DeGregorio Foundation Award for Cancers of the Upper GI Tract
Deadline: October 31

American Society of Hematology
Deadline: November 1

Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease Awards
Deadline: November 1

Melanoma Research Alliance Young Investigator Awards
Proposal Deadline: November 13

Melanoma Research Alliance Established Investigator Academic-Industry Partnership Awards
Proposal Deadline: November 13

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Limited Competition: Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE)(U54)(PAR-12-055)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.