Case Comprehensive Cancer Center: Weekly Newsletter

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January 28, 2013
CASE CCC IN THE NEWS Researchers Discover Promising Prognostic Marker for Aggressive Breast Cancer Case CCC News - Jan 23, 2013 A team of researchers led by Goutham Narla, MD, PhD, at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, and collaborators at the Mount Sinai School of Medicine and Erasmus Medical Center, have discovered a gene variant that drives the spread of breast cancer. Published in Scientific Translational Medicine, the study lays the early foundation for predicting which breast cancer patients may develop more aggressive disease and for designing more effective treatments. First Harrington Distinguished Scholar Brings Breast Cancer Research to Cleveland Plain Dealer-Jan 24, 2013 A native of California, Dr. Goutham Narla moved East after graduating from Santa Clara University. He would spend the next 15 years in New York City...An added bonus: Narla's wife, Analisa DiFeo, is furthering her ovarian cancer research at her own lab at Case Comprehensive Cancer Center, which she joined last spring. Collaboration in academia designed to increase return on research investments Helio/HemOnc Today - Jan 25, 2013 Point by Brian J. Bolwell, MD, FACP...Private-public partnerships are a very good option. There are certain realities that exist in 2013. The first is that overall reimbursement in health care is declining and will continue to do so... Cleveland Clinic Opens Wig and Cap Boutique for its Cancer Patients Plain Dealer - Jan 23, 2013 Barrat-Gordon and Lindecke credit Dr. Brian Bolwell, Taussig chairman since summer 2011 (he was interim chairman prior to that), with creating the atmosphere that makes the new boutique possible. Highlights From the 2013 Gastrointestinal Symposium, with Neal Meropol, MD Cancer.Net (video) In this podcast, we review some of the news announced at the 2013 Gastrointestinal Cancer Symposium, co-sponsored by ASCO. Drug Is Shown to Help Pancreatic Cancer Cases New York Times - Jan 22, 2013 "The simplicity of Abraxane plus gemcitabine may be attractive to physicians and patients," said Dr. Neal J. Meropol, chief of hematology and oncology at University Hospitals and Case Western Reserve University in Cleveland... ANNOUNCEMENTS Miltenyi Biotec to Contribute Portion of Purchases to Support TRCCC Conference Miltenyi Biotec is offering special discounts in relation to the upcoming TRCCC conference. Special offers include: 10% off gentleMACS™ or gentleMACS™ Octo Dissociators Plus FREE MACS® Tumor Dissociation Kit of choice Plus 25 FREE gentleMACS™ C Tubes for tumor dissociation Plus 5% TRCCC contribution – 5% of the gentleMACS purchase price will be contributed by Miltenyi Biotec to sponsor the TRCCC meeting, February 20-23, 2013 Click here for more information. FUNDING OPPORTUNITIES/AWARDS American Cancer Society IRG Awards The Case CCC, with funds from its American Cancer Society Institutional Research Grant, will provide seed money to foster cancer research by junior faculty who have no current national grant support of their own. Investigators in the CWRU School of Medicine and Cleveland Clinic Lerner College of Medicine as well as in other schools and colleges in the University are eligible. Grants, not to exceed $30,000, will be awarded to investigators who intend to gather preliminary data to be used in seeking future and independently funded programs. LOI Deadline: February 18 Application Deadline: April 5 Alex's Lemonade Stand Foundation Pediatric Oncology Student Training Program Alex's Lemonade Stand Foundation (ALSF) is dedicated to funding pediatric oncology researchers at critical points in their careers. The Pediatric Oncology Student Training (POST) Program is designed for graduate and medical students who have an interest in pediatric oncology research and would like to experience the field first hand. Students train with a pediatric oncology research mentor. Students may join a research project underway in a mentor's lab or begin an original investigation with the mentor. Deadline: March 4 MARK YOUR CALENDARS Grant Writing Workshops The CWRU Office of Research Administration is pleased to announce that Dr. Bob Lucas, Director of the Institute for Scholarly Productivity in San Luis Obispo, California, will be on campus to present two grant writing workshops: Scholarly Writing Thursday, January 31 2-5:30 pm BRB 105 This workshop is intended for academics who are writing less than they would like. It assumes that many professors have done a great deal of publishable research –they just haven't written up the results. Introduction to Proposal Writing Friday, February 1 8 am - 12 pm WRB 1-413 This workshop introduces academics to the grants world. It gives beginners a framework for understanding this complex world and advice about how best to expend their energies to gain the maximum return from their efforts. Register today! TRCCC Annual Meeting: The Power of Negative Thinking: Inhibiting the Inhibitors of Tumor Immunity Registration is open for the 16th Annual Meeting of the Translational Research Cancer Centers Consortium (TRCCC), The Power of Negative Thinking: Inhibiting the Inhibitors of Tumor Immunity. Held February 20-22 at the Seven Springs Mountain Resort in Seven Springs, PA, this meeting will feature two symposiums focused on Tumor-mediated Immune Suppression and Vaccine and Cellular Therapy, with spotlight sessions on Imaging and Viral Vectors. The agenda will also include a poster session. Researchers, institutional officials, and students are invited to submit abstracts for poster presentations by February 4.	EVENTS January 28 Pathology Research Seminar Series Youwei Zhang, PhD Assistant Professor, Pharmacology CWRU Topic: Cell Cycle Checkpoint Regulation and Cancer Therapy 12 pm WRB 1-413 January 29 Radiation Oncology Grand Rounds Rod Ellis, MD Assistant Professor, Radiation Oncology CWRU/UH Topic: The Clinical Implications for the Increasing Role of Molecular Imaging in Radiation Oncology 8:10 am Lerner Tower B-181 Immunology Seminar Series Joanne Turner, PhD Associate Professor, Internal Medicine and Molecular Virology, Immunology, and Medical Genetics Center for Microbial Interface Biology The Ohio State University Topic: IL-10 Deficiency reverses the TB Susceptibility Phenotype of CBA/J mice 12 pm WRB 1-413 Medicine Grand Rounds Kim Bixenstine Deputy General Counsel and VP, Claims and Litigation Services University Hospitals Topic: Joint Compliance and Legal Presentation on HIPAA and Patient Privacy Issues 12 pm Kulas Auditorium, Lakeside 5th Fl. January 30 Hematology and Oncology Division Research Conference Evi Stavrou, MD Instructor, Div. of Hem/Onc CWRU/UH Topic: Factor XII: A Critical Regulator of Thrombosis and Leukocyte Function 8 am Lerner Tower B-151 January 31 February 1 Hematology/Oncology Fellows Conference/Curriculum Series Topic: TBD 8 am School of Nursing 2280 Taussig Cancer Institute Grand Rounds Sree Battu, MD Cleveland Clinic Topic: Cancer Rehabilitation 8 am R3/002-003 Cleveland Clinic Engineering and Medicine Seminar Daniel Hammer, PhD Alfred G. and Meta A. Ennis Professor of Bioengineering Professor, Chemical Engineering and Biomolecular Engineering University of Pennsylvania Topic: Force Microscopy of Amoeboid Cell Motility 10 am Wickenden 322 Cancer Center Seminar Series Ruth Keri, PhD Associate Director for Basic Research, Case CCC Associate Professor and Vice Chair, Pharmacology CWRU Topic: Regulation of Breast Cancer Phenotypes 12 pm BRB 105 Molecular Biology and Microbiology Thesis Presentation Mastooreh Chamanian Arts Lab, Molecular Biology and Microbiology CWRU Topic: A Novel HIV-1 Genomic RNA Packaging Element and its Role in Interplay Between RNA Packaging and Ribosomal Frameshifting 1 pm Wood Building, W203 Rottman Seminar Room Cancer Center Research in Progress Stephen Fink, PhD Instructor, Markowitz lab, Div. of Hem/Onc CWRU/UH Topic: CCSP-1, A Secreted Protein Highly Induced in Colon Cancer and Associated with Poor Survival 4 pm WRB 3-136 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS The Role of Interferon in Metastasis and Resistance to DNA Damage in Prostate Cancer February 7 Cleveland Clinic Room Q1-300 Agenda and Registration IMPACT: Improving Sickle Cell Patient Adherence Through Collaborative Teaching March 23 Wolstein Research Building Brochure and Registration Breast Cancer Conference May 17 Hilton Cleveland East ADDITIONAL UPCOMING SEMINARS & EVENTS 16th Annual Meeting of the Translational Research Cancer Centers Consortium (TRC3): The Power of Negative Thinking: Inhibiting the Inhibitors of Tumor Immunity February 20-22 Seven Springs Mountain Resort, Seven Springs, PA Details National GvHD Health Symposium November 1

PREVIOUSLY ANNOUNCED OPPORTUNITIES
Sarcoma Foundation of America Deadline: January 31 Limited Submission: NIH Shared Instrumentation Grant Program LOI Deadline: February 1 Application Due to Sponsor: March 21 National Research Council Associateship Programs Deadline: February 1 Oncology Nursing Society Foundation Master's Degree Scholarships Deadline: February 1 Oncology Nursing Society Foundation Doctoral Degree Scholarships Deadline: February 1 Prostate Cancer Foundation 2013 Young Investigator Awards Deadline: February 1 Avon Foundation 2013 Breast Cancer Research Program LOI Deadline: February 4 Invited Full Proposal Deadline: April 1 Case CCC ACS IRG LOI Deadline: February 18 Application Deadline: April 5 Leukemia and Lymphoma Society Translational Research Program LOI Deadline: March 1 Full Application Deadline: March 15 Childhood Brain Tumor Foundation Deadline: March 12	Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC) Deadline: Open AACR Scholar-in-Training Awards - Other Conferences and Meetings Deadline: Open Case CCC Protocol Specific Research Support (PSRS) Deadline: Open International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program Application Deadline: Open James S. McDonnell Foundation Collaborative Activity Awards Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open SAIC-Frederick Support of the Cancer Genome Atlas Program Application Deadline: Open Solving Kids' Cancer Therapeutic Development Initiative Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities Notice of Intent to Publish the Reissuance of PA-10-006 "Mechanisms, Models, Measurement, & Management in Pain Research (R01)" (NOT-NR-13-006) Notice of Intent to Publish the Reissuance of PA-10-008 "Mechanisms, Models, Measurement, & Management in Pain Research (R03)" (NOT-NR-13-008) Notice of Intent to Publish the Reissuance of PA-10-007 "Mechanisms, Models, Measurement, & Management in Pain Research (R21)" (NOT-NR-13-007) PHS 2013-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])(PA-13-089) Notice of New Application Due Date with Temporary Increase in Budget Limit on AHRQ Large Research (R01) and Demonstration (R18) Grant Applications for Standing AHRQ Funding Opportunity Announcements (FOAs)(NOT-HS-13-005)
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216.844.8317 phone 216.844.7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.