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Case Comprehensive Cancer Center Newsletter

December 10, 2012

CASE CCC IN THE NEWS

Vitamin D cuts breast cancer death risk in overweight and obese
Food Consumer - Dec 9, 2012
M. L. Morton and C. L. Thompson at Case Comprehensive Cancer Center, Case Western Reserve University in Cleveland, OH, USA reviewed ...


ANNOUNCEMENTS

Dr. Neal Meropol Appointed to American Society of Clinical Oncology Board of Directors

meropolThe American Society of Clinical Oncology (ASCO) today announced the appointment of Neal J. Meropol, MD, to its 18-member Board of Directors. ASCO is the world's leading professional organization representing physicians who care for people with cancer.

The ASCO Board of Directors is responsible for executing the mission, vision and strategic management of the organization and translating ASCO's mission into ongoing programs that attain the organization's goals. With more than 30,000 members, ASCO is committed to improving cancer care through scientific meetings, educational programs and peer-reviewed journals. [more]

Dr. David Wald Honored with Ohio Cancer Research Associates Award

walddDr. David Wald was recently honored with the "Seed Money Award" from the Ohio Cancer Research Associates (OCRA) for his work in leukemia drug development. A $60,000, two-year seed-money grant from OCRA enabled Dr. Wald and his research team to secure an additional $2.62 million in national funding–$1.9 million from the National Institutes of Health and $720,000 from the American Cancer Society–for his cancer drug development research.

Dr. Sanford Markowitz Recognized as a Top-Physician Scientist by Harrington Scholar-Innovator Grant

markowitzsDr. Sanford Markowitz was one of only ten recipients nation-wide of the inaugural Harrington Scholar-Innovator grants, given out by the Harrington Discovery Institute at UH Case Medical Center. This program is focused on supporting the nation's best physician-scientists and their efforts to accelerate promising drug discoveries into novel treatments for patients.

A competitive grant competition was held in May to identify the nation's most promising medical breakthroughs and to accelerate their entry into the clinic. Dr. Markowitz was selected for his research on Pulmonary HTN & Liver Regeneration: Discovery of a novel compound that increases tissue prostaglandins to treat multiple human diseases, including pulmonary hypertension, liver regeneration and cancer.

Obtaining Human Tissues for Cancer Research

The Case CCC wishes to make its members aware that a Data Use Agreement has been approved by the University Hospitals Legal Affairs Office. This Data Use Agreement will greatly facilitate obtaining tissue for cancer research in situations where protected health information is not necessary for the research.

A wide variety of tissues is available from the Tissue Resources Core, and samples from the hospital's clinical archives of paraffin-embedded tissues may also be obtained. You are encouraged to visit the Tissue Resources website for information about available biospecimens. Application forms are accessible from the Case CCC Tissue Resources page, and from the Clinical Research Office page.

Use the Tissue Research Application for studies that involve research activities limited to archived or discarded tissue. Contact David Goldblatt at 216.844.5060, david.goldblatt@case.edu and/or Kristin Waite at 216.844.5537, kristin.waite@case.edu for guidance on the application process.


FUNDING OPPORTUNITIES/AWARDS

Limited Submission: Mary Kay Foundation

The Mary Kay Foundation is currently accepting applications for innovative grants for translational research in ovarian, uterine, breast, or cervical cancer. The Case CCC may submit ONE grant application. Interested candidates should forward the project abstract and their biosketch to Kristin Waite by January 4, 2013.

Internal Deadline: January 4, 2013
External Deadline: February 4, 2013

Limited Submission: Samuel Waxman Cancer Research Foundation Individual Research Proposals

The Samuel Waxman Cancer Research Foundation (SWCRF) seeks to develop scientific programs in the form of an Institute Without Walls. These programs span multiple institutions and disciplines and identify the optimal set of investigators to unravel and reverse the abnormal program of growth and differentiation of the cancer cell. The Foundation envisions that members of the SWCRF Institute Without Walls will continue interactions beyond the term of their grant. The focus of this RFA is the identification of targets, novel compounds, and potential therapies that can reprogram abnormal cancer gene function. Specific themes of interest to the SWCRF include studies that address aberrant gene regulation, transcriptional and signal transduction, epimutations, and cell dormancy vs. proliferation.

The Case CCC has been invited to submit ONE application for this opportunity. Interested candidates should forward the project abstract and their biosketch to Kristin Waite.

Internal Deadline: January 25, 2013
External Deadline: March 18, 2013

National Research Council Associateship Programs

The National Research Council of the National Academies is pleased to announce the Graduate, Postdoctoral and Senior Research Associateship Programs for 2013. These programs provide opportunities for PhD, ScD, or MD scientists and engineers of unusual promise and ability to perform research on problems largely of their won choosing, yet compatible with the research interests of the sponsoring laboratory.

Application deadlines are February 1, May 1, August 1 and November 1.

Prostate Cancer Foundation 2013 Young Investigator Awards

The Prostate Cancer Foundation (PCF) is accepting applications for the 2013 Young Investigator Awards. Highly innovative basic science programs will be carefully considered, but priority will be given to "bench to bedside" translational research proposals with the potential to deliver near term benefit to patients. PCF welcomes applications from the global community. Applicants need not be trained specifically in clinical prostate cancer research. Young Investigators may be working in basic, translational, clinical, population sciences, bioengineering or any other field that could contribute to the end of prostate cancer. However, successful applicants should be working in a research environment capable of supporting transformational prostate cancer research. Access to and interaction with a clinical environment, as well as translational prostate cancer physician-scientists, is highly desirable. Research molecular pathologists and bioinformaticians are especially encouraged to apply for this award.

Deadline: February 1, 2013

Leukemia and Lymphoma Society Translational Research Program

The Leukemia and Lymphoma Society (LLS) has released an RFP for its Translational Research Program (TRP). This program was developed to encourage and provide early-stage support for clinical research in leukemia, lymphoma and myeloma, which is intended to develop innovative approaches to treatment, diagnosis or prevention. Proposals should be based on molecular, cellular or integrated systems findings and be conceptually innovative. The application should have a clear plan for the clinical exploitation of the studies proposed and the results expected. This feature of the proposal will be an important consideration of the review process. While work directed at a further elucidation and understanding of the fundamental cellular and molecular biology of neoplastic lymphohematopoietic cells is a research priority of LLS, the TRP is specifically intended for the support of work which is clearly clinical in orientation with an overall goal to result in a clinical trial and/or TRP renewal.

LOI Deadline: March 1, 2013
Full Application Deadline: March 15, 2013


MARK YOUR CALENDARS

Monthly Cancer Trainee Seminar Series

The Cancer Trainee Seminar Series is a monthly seminar open to anyone working on a cancer-related project, though it is focused on cancer biology trainees. In this series, a trainee will give a 30-minute talk on their work, followed by a 20-minute talk by a clinician who may present on the same disease as the trainee, but from a clinical point of view.<.

This seminar series serves multiple purposes. First, it provides trainees with a cancer-centric audience of their peers and faculty members, to allow them to receive critical feedback on their presentation skills. Second, the series exposes trainees to the clinical management of cancer. This component of the series was included because there was a general consensus among trainees that they wanted more clinical exposure to cancer in order to enable them to extend their basic research findings into the translational research arena. Finally, the series can facilitate collaborative interaction among trainees from different departments, where interactions may be less likely.

These meetings will be held the third Thursday of each month at 12 pm in Wolstein Research Building 3-136. Lunch will be provided. If you have a trainee you think might benefit from this series, please send their e-mail address to Kristin Waite (kristin.waite@case.edu), so they can be added to the mailing list.

EVENTS

calendar

December 10

Cancer Center Research Chalk Talk
John Wang, PhD
Associate Professor, Genetics
CWRU
Topic: TBD
12 pm WRB 3-136

Stem Cell Biology and Regenerative Medicine Seminar Mid-Term Review
Jeongwu Lee, PhD
Assistant Professor, Stem Cell Biology and Regenerative Medicine
CWRU/Cleveland Clinic
Topic: Targeting Stem Cell Pathways in Cancer
10 am NE1-205 Cleveland Clinic

Pathology Research Seminar Series
Bingwei Lu, PhD
Associate Professor, Pathology
Stanford University
Topic: Mitochondrial Quality Control in Development and Disease
12 pm WRB 1-413

Sequencing Data Interest Group
Xiaoqing Yu, PhD
PhD Student, Epidemiology and Biostatistics
Topic: HMM-DM: Identifying Differential Methylation Patterns Using A Hidden Markov Model
2:30 pm WRB 1-402

Skeletal Research Center Seminar
Tracey Bonfield, PhD
Director, Inflammatory Mediator Core Facility
Assistant Professor, Div. of Pediatric Pulmonology
CWRU
Topic: Mesenchymal Stem Cells: New Options for Lung Diseases
4 pm Millis 123


December 11

Molecular Genetics Departmental Seminar Series
Shuang Ma, PhD
Postdoctoral Research Fellow, Rubin Lab, Molecular Genetics
Cleveland Clinic
Topic: Apoptosis Associated Tyrosine Kinase Promotes Metastasis of Melanoma Cells
9:30 am NE1-205 Cleveland Clinic

Immunology Seminar Series
Dario Vignali, PhD
Vice Chair, Immunology
St. Jude Children's Research Hospital
Topic: Molecular Control of Regulatory T Cell Stability and Function
12 pm WRB 1-413


December 12

Hematology and Oncology Division Research Conference
Jane Little, MD
Associate Professor, Div. of Hem/Onc
CWRU/UH
AND
Connie Piccone, MD
Assistant Professor, Pediatric Hem/Onc
CWRU/UH
Topic: Improving Adherence in Patients with Sickle Cell Disease
8 am Lerner B-151

Genetics and Genome Sciences Seminar
David Jones, PhD
Senior Director, Early Translational Research
Professor, Oncological Sciences
University of Utah/Hunstman Cancer Center
Topic: APC Control of DNA Methylation Dynamics in Intestinal Differentiation and Colorectal Cancer
11 am SOM 105

Immunology Faculty Research in Progress Series
Robert Fairchild, PhD
Professor, Immunology
CWRU/Cleveland Clinic
Topic: Faculty Update
12 pm NC1-202 Cleveland Clinic

20th Annual Robert R. Kohn Lecture
Rama Natarajan, PhD
Endowed Professor and Associate Chair, Diabetes
Director, Div. Molecular Diabetes Research
Beckman Research Institute of the City of Hope
Topic: Epigenetic Mechanisms & MicroRNAs Underlying Inflammation in Diabetic Vascular Complications & Metabolic Memory
4 pm WRB 1-413


December 13

Stem Cell Biology and Regenerative Medicine Seminar
Cornelia Bergmann, PhD
Staff, Neurosciences
Cleveland Clinic
Topic: Modulation of Lymphocyte Function by Glial Cells
1 pm NE1-205 Cleveland Clinic

Cancer Center Seminar
Shaying Zhao, PhD
Associate Professor, Biochemistry and Molecular Biology, Institute of Bioinformatics
University of Georgia
Topic: Sporadic Canine Cancers as Genetic and Epigenetic Models of Human Cancers
2 pm WRB 3-136


December 14

Hematology/Oncology Fellows Conference/Curriculum Series
Paula Silverman, MD
Professor, Div. of Hem/Onc
CWRU/UH
AND
Hannah Gilmore, MD
Assistant Professor, Pathology
CWRU/UH
Topic: Interdisciplinary Approach to Breast Cancer
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Peter Mazzone, MD, MPH
Staff, Pulmonary, Allergy and Critical Care Medicine
Cleveland Clinic
Topic: Lung Cancer Screening: Past, Present and Future
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
David Boothman, PhD
Professor, Pharmacology and Radiation Oncology
Associate Director for Translational Research
University of Texas Southwestern/Simmons Comprehensive Cancer Center
Topic: Kub5/Hera (K/H), A Protein at the Crossroads Between RNA Termination and DSB Repair
12 pm BRB 105

Cancer Center Research in Progress
Kristy Miskimen, PhD
Research Associate, Harris Lab, Div. of Hem/Onc
CWRU/UH
Topic: Using Next-Generation Sequencing to Predict Response to Therapy in Breast Cancer
4 pm WRB 3-136

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

16th Annual Meeting of the Translational Research Cancer Centers Consortium (TRC3): The Power of Negative Thinking: Inhibiting the Inhibitors of Tumor Immunity
February 20-22, 2012
Seven Springs Mountain Resort, Seven Springs, PA
Check back for more information

 

ADDITIONAL UPCOMING SEMINARS & EVENTS

American Society of Hematology (ASH) Annual Meeting
December 8-11
Atlanta, Georgia
Details

So You Want To Do Comparative Effectiveness Research? The Nuts and Bolts of CER
December 14
7:30 am - 12 pm WRB 1-413
Details

Pacific Symposium on Biocomputing 2013
January 3-7, 2013
Fairmont Orchid, Hawaii
Details


PREVIOUSLY ANNOUNCED OPPORTUNITIES

CTSC Explorys Collaborative Pilots
Deadline: December 14

Oncology Nursing Certification Corporation: Advanced Oncology Certified Nurse of the Year Award
Deadline: December 15

Alex's Lemonade Stand Foundation Epidemiology Awards
Deadline: December 17

Alex's Lemonade Stand Foundation Young Investigator Awards
Deadline: December 17

AACR Basic Cancer Research Fellowships
Deadline: December 20

Association for Research of Childhood Cancer
Deadline: January 1, 2013

Beez Foundation for Pediatric Brain Cancer
Deadline: January 2, 2013

AACR-Millennium Fellowship in Lymphoma Research
Deadline: January 7, 2013

AACR-Millennium Fellowship in Prostate Cancer Research
Deadline: January 7, 2013

Society of Surgical Oncology Clinical Investigator Awards
Deadline: January 7, 2013

2013 CTSC Annual Pilot Grant Funding
LOI Deadline: January 15, 2013

Oncology Nursing Society Foundation Master's Degree Scholarships
Deadline: February 1, 2013

Oncology Nursing Society Foundation Doctoral Degree Scholarships
Deadline: February 1, 2013

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

James S. McDonnell Foundation Collaborative Activity Awards
Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01)(PAR-13-036)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.