Case Comprehensive Cancer Center: Weekly Newsletter

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November 12, 2012
CASE CCC IN THE NEWS immatics' Renal Cancer Vaccine IMA901 Completes Phase 3 Patient Recruitment and is Granted US Orphan Drug Designation by the FDA Barron's - Nov 8, 2012 Chief investigator of the trial is Professor Brian Rini, Lerner College of Medicine, Department of Solid Tumor Oncology at the Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio... Kirtland Girl's Cancer Battle Gets Mention in President Obama's Acceptance Speech Plain Dealer - Nov 8, 2012 Dr. Jeffery Auletta, Erin's doctor, confirmed she is in remission. "And we are hopeful that it will continue in the future." Auletta, a hematologist ... President Obama Gives a Shout-out to Mentor Girl Battling Leukemia on Election Night NewsNet5.com - Nov 7, 2012 "I think the comment he made after he mentioned Erin was really something that is important to all of us," said Erin's doctor, John Letterio, the Chief of Pediatric ... High-Carb Diet Linked to Colon Cancer Recurrence in Study U.S. News & World Report - Nov 7, 2012 An accompanying journal editorial by Dr. Neal Meropol and Dr. Nathan Berger -- both from the division of hematology and oncology at ... FUNDING OPPORTUNITIES American Association for Cancer Research The American Association for Cancer Research (AACR) is accepting applications for the following opportunities: The Landon Foundation-AACR INNOVATOR Award for Cancer Prevention Research was established to recognize the outstanding achievement of a junior faculty-level scientist working in the field of cancer prevention, and support his or her novel and innovative research that, if successful, will have strong potential for high impact in the cancer prevention field. The goals of the grant program are to encourage an outstanding, creative young investigator to pursue novel, high-risk, high-reward cancer prevention research by providing the support that otherwise may not be available through traditional funding. Travel support is included to help foster interactions among cancer scientists working in various disciplines and to disseminate scientific knowledge about cancer prevention research throughout the field. Deadline: November 20 The AACR-National Brain Tumor Society Career Development Award for Translational Brain Tumor Research represents a joint effort to encourage and support junior faculty who are in the first five years of a faculty appointment (at the start of the grant term) to conduct brain tumor research and establish successful career paths in this field. The research proposed for funding must be translational in nature and have direct applicability and relevance to brain tumors. Deadline: November 30 CTSC Explorys Collaborative Pilot The CTSC is accepting applications for Explorys Collaborative Pilots. The purpose of this pilot funding opportunity is to innovate and collaborate with Explorys informatics personnel to develop novel or enhance existing approaches for expanding the use of BIG DATA in organizing, integrating, searching, analyzing, or visualizing health care data. Successful applications will involve two or more disciplines, with a focus on building innovative clinical research informatics, aligned with a key Explorys focus area as listed above and allocate no more than a third of the budget on supporting development efforts or analysis by Explorys. Deadline: December 14 MARK YOUR CALENDARS Measuring Biomarkers with Meso Scale Discovery John Pink, PhD and Paul Hartman, MS of the Translational Research & Pharmacology Core Facility invite you to a presentation by Jim Kepka, Regional Director of Meso Scale Discovery (MSD) on Wednesday, November 14 at 12:30 pm in WRB 2-136. Light lunch will be provided. Presentation and discussion will include: Core Technology Overview Assays for Cytokines, Intracellular Signaling & Metabolic markers Phase-gated Process for Assay Development and QC Please RSVP to John Hudson at jhudson@mesoscale.com or 630.547.5148. MSD offers a diverse product line of biomarker assays including many oncology-focused kits. They feature phospho-protein and intracellular signaling assay kits designed for use with whole cell lysates and others complex matrices. Clinical biomarker assays for analysis of serum, plasma and tissue culture samples are also available. ANNOUNCEMENTS Cancer Care Video Challenge The Office of the National Coordinator for Health Information Technology (ONC) in conjunction with the National Cancer Institute (NCI), invites cancer patients, survivors, and their families and friends to create short, compelling videos sharing a personal story that describes a goal of a cancer patient or survivor, and how technology (such as health IT or consumer eHealth tools) is used to support meeting that goal. There are a variety of tools and applications that can be used to help patients and their families navigate the various aspects of living with or transitioning from cancer treatment to survivorship. The purpose of the challenge is to generate videos that will inspire and motivate others to become more engaged in their care, through the use of consumer e-health tools and other health IT to improve communication and collaboration with their health care team (doctors, nurses, and other allied health care professionals), and better manage their cancer-related care. The deadline to submit a video is December 21. Cash prizes are available to the winners.	EVENTS November 12 Cancer Center Chalk Talk Alvin Schmaier, MD Professor, Medicine-Hematology/Oncology CWRU/UH Topic: TBD 12 pm WRB 3-136 Pathology Research Seminar Series Jeongwu Lee, PhD Assistant Professor, Stem Cell Biology and Regenerative Medicine CWRU/Cleveland Clinic Topic: Stat 3 Activation by the Epigenetic Silencer EZH2 in Brain Tumor 12 pm WRB 1-413 November 13 Molecular Genetics Departmental Seminar Series Saurabh Chattopadhyay, PhD Project Staff, Sen Lab, Molecular Genetics Cleveland Clinic Topic: RIPA: A New Antiviral Pathway 9:30 am NE1-205 Cleveland Clinic Department of Cancer Biology Invited Speaker Seminar Petra Hamerlik, PhD Research Fellow, Stem Cell Biology and Regenerative Medicine Cleveland Clinic Topic: Autocrine VEGFR2 Signaling in Glioma Stem-like Cells Evades VEGF Neutralization 11 am NC1-202 Cleveland Clinic Austin S. Weisberger Lecture Susan B. Shurin, MD Deputy Director, National Heart, Lung, and Blood Institute National Institutes of Health Topic: Benign Hematology: Back to the Future 12 pm Kulas Auditorium, Lakeside 5th Fl. Immunology Seminar Series Ken Murphy, MD, PhD Eugene Opie First Centennial Professor, Pathology and Immunology Investigator, Howard Hughes Medical Institute Washington University Topic: Dynamics of Dendritic Cell Development During Infection 12 pm WRB 1-413 Molecular Biology and Microbiology Seminar Jia Liu, PhD Assistant Scientist, Molecular Genetics and Microbiology University of Florida Topic: Discovering Host Antiviral Factors Through Studies of Poxvirus Host Range Factors 1 pm Rottman Seminar Room, W203 November 14 Hematology and Oncology Research Conference Shigemi Matsuyama, PhD Associate Professor, Div. of Hem/Onc CWRU/UH Topic: Bax-mediated Programmed Cell Death: Molecular Mechanism and Technologies Controlling Cell Death 8 am Lerner B-151 Department of Neuroscience Guest Speaker Tajie H. Harris, PhD Research Associate, Pathobiology University of Pennsylvania Topic: T Cell Migration and the Control of Toxoplasma Gondii in the Brain 10 am NE1-205 Cleveland Clinic Immunology Faculty Research in Progress Series Brian Gastman, MD Associate Professor, Plastic Surgery and Immunology CWRU/Cleveland Clinic Topic: Mcl1 and Chemotherapeutic Resistance 12 pm NC1-202 Cleveland Clinic Innovative Science Discussion Group Topic: TBD 12:15 pm WRB 3-136 Measuring Biomarkers with Meso Scale Discovery November 14 Jim Kepka, Regional Director, Meso Scale Discovery 12:30 pm WRB 2-136 LRI Showcase Seminar Jun Qin, PhD Professor, Molecular Cardiology CWRU/Cleveland Clinic Topic: Understanding hierarchy of integrin adhesome and its dysregulation: A structure-based approach 4:30 pm NE1-205 Cleveland Clinic November 15 Molecular Genetics Seminar Andrew Craig, PhD Associate Professor, Biomedical & Molecular Sciences Queens University Topic: F-BAR Proteins Regulate Lung Cancer Progression and Metastasis 9:30am NE1-205 Cleveland Clinic Special Presentation: Hematology and Oncology Research Conference Yan Feng, MD, PhD Fellow, Hematology and Oncology Cleveland Clinic Topic: ALK Rearranged Non-small Cell Lung Cancer - From Bench to Bedside 12 pm Wearn 137 November 16 Hematology/Oncology Fellows Conference/Curriculum Series Evi Stavrou, MD Fellow, Div. of Hem/Onc CWRU/UH Topic: Introduction to Hemostasis and Coagulation Journal Club 8 am Wearn 137 Taussig Cancer Institute Grand Rounds Yan Feng, MD Hematologic Malignancies and Blood Disorders Cleveland Clinic Topic: Molecular Profile and CTC Detection of ALK 2p23 Translocation 8 am R3/002-003 Cleveland Clinic Cancer Center Seminar Series Ernest Borden, MD Professor, Translational Hematology and Oncology Research CWRU/Cleveland Clinic Topic: Curing Melanoma: The Case CCC Therapeutics Pipeline 12 pm BRB 105 Radiation Oncology Grand Rounds Maria Thomas, MD, PhD Radiation Oncology Washington University in St. Louis Topic: PET Imaging for Cervical Cancer 12 pm Lerner Tower B-151 Cancer Center Research in Progress Xiujing Feng, PhD Postdoctoral Scholar, Wang Lab, Genetics CWRU Topic: Tumor Suppressor Protein Tyrosine Phosphatase PTPRT Regulates Intestinal Stem Cell Proliferation 4 pm WRB 3-136 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS ADDITIONAL UPCOMING SEMINARS & EVENTS The Cancer Genome Atlas 2nd Annual Scientific Symposium: Enabling Cancer Research Through TCGA November 27-28 Crystal City, Virginia Details American Society of Hematology (ASH) Annual Meeting December 8-11 Atlanta, Georgia Details So You Want To Do Comparative Effectiveness Research? The Nuts and Bolts of CER December 14 7:30 am - 12 pm WRB 1-413 Details Pacific Symposium on Biocomputing 2013 January 3-7, 2013 Fairmont Orchid, Hawaii Details

PREVIOUSLY ANNOUNCED OPPORTUNITIES
AACR Scholar in Training Awards Deadline: November 15 AACR Dharma Master Jiantai Innovative Grant for Lung Cancer Research Deadline: November 20 Limited Submission: NIH Director's Early Independence Award Internal Deadline: November 26 LOI Deadline: December 30 Full Application: January 30, 2013 Limited Submission: Rita Allen Foundation Scholars Program Internal Deadline: November 26 External Deadline: January 25, 2013 AACR Minority Scholar in Cancer Research Award Deadline: November 30 AACR-Thomas J. Bardos Science Education Awards for Undergraduate Students Deadline: November 30 AACR-Women in Cancer Research (WICR) Scholar Awards Deadline: November 30 Alex's Lemonade Stand Foundation Innovation Grants Deadline: December 3 Conquer Cancer Foundation of ASCO Medical Student Rotation for Underrepresented Populations Deadline: December 3 Weatherhead Institute for Family Medicine and Community Health Pilot Deadline: December 3 DOD Breast Cancer Research Program Postdoctoral Fellowship Award Pre-Application Deadline: December 4 Application Deadline: December 18 Alex's Lemonade Stand Foundation Epidemiology Awards Deadline: December 17	Alex's Lemonade Stand Foundation Young Investigator Awards Deadline: December 17 Association for Research of Childhood Cancer Deadline: January 1, 2013 2013 CTSC Annual Pilot Grant Funding LOI Deadline: January 15, 2013 Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC) Deadline: Open AACR Scholar-in-Training Awards - Other Conferences and Meetings Deadline: Open Case CCC Protocol Specific Research Support (PSRS) Deadline: Open International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program Application Deadline: Open James S. McDonnell Foundation Collaborative Activity Awards Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open SAIC-Frederick Support of the Cancer Genome Atlas Program Application Deadline: Open Solving Kids' Cancer Therapeutic Development Initiative Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities Small Grants Program for Cancer Epidemiology (R03)(PAR-12-039) Notice of Intent to Publish a Funding Opportunity Announcement for Bridging the Gap Between Cancer Mechanism and Population Science (U01)(NOT-CA-13-001) Early-Stage Innovative Molecular Analysis Technology Development for Cancer Research (R21)(RFA-CA-13-001) Validation and Advanced Development of Emerging Molecular Analysis Technologies for Cancer Research (R33)(RFA-CA-13-002) Early-Stage Development of Innovative Technologies for Biospecimen Science (R21)(RFA-CA-13-003) Validation and Advanced Development of Emerging Technologies for Biospecimen Science (R33)(RFA-CA-13-004)
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216.844.8317 phone 216.844.7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.