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Case Comprehensive Cancer Center Newsletter

November 5, 2012

CASE CCC IN THE NEWS

University Hospitals, Mercy health system entering cancer treatment ...
Crain's Cleveland Business - Nov 1, 2012
Dr. Nathan Levitan, president of UH Seidman Cancer Center, told Crain's this summer the health system's cancer program has seen a four-fold ...

A 3D tool to Track Malformations in Unborn Heart!
BioScholar News - Oct 31, 2012
... stress by modulating the heart rate, but it may also involve vigour and/or timing of the contraction," said Andrew Rollins, senior study author.

Stereotactic Radiosurgery Shows Promise for Kidney Cancer
Medical Xpress - Oct 31, 2012
Rod Ellis, MD, lead author of the study along with Lee Ponsky, MD, who is the Principal Investigator, presented results of a Phase 1 clinical trial ...

Hair loss: Is it Your Age, Hormones, Weight or Environment?
Plain Dealer - Oct 29, 2012
Dr. Elma Baron, a dermatologist at University Hospitals Case Medical Center, says that topical minoxidil is by far the main treatment offered for ...


ANNOUNCEMENTS

2013 The Scott Hamilton CARES Initiative Grant Program Recipients

The following investigators were recipients of the 2013 The Scott Hamilton CARES Initiative grant program. All four were recognized at the 13th annual An Evening with Scott Hamilton and Friends on Saturday, November 3. Recipients and their research studies are as follows (cancer center members are indicated in bold):

  • Mellar Davis, MD: A Pilot Study for the Evaluation of Cognitive Impairment in Women Undergoing Adjuvant Chemotherapy
  • Shunji Egusa, PhD: A Versatile Novel Technology to Target Oncotherapeutics to Cancer Cells
  • Olga Stenina, PhD: Tissue-Specific Regulation of Diabetes-Associated Cancer Growth
  • Ramon Tiu, MD: Role of SF3B1 in the Pathogenesis of Myelodysplastic Syndromes

Recipients, based on scientific merit, were determined by peer reviewers from the Taussig Cancer Institute and Lerner Research Institute. As a key mission of The Scott Hamilton CARES Initiative, the research grant funding program seeks to support innovative cancer research at Cleveland Clinic. The CARES grant program is funded through the annual ice show and gala.


FUNDING OPPORTUNITIES

James S. McDonnell Foundation Collaborative Activity Awards

The James S. McDonnell Foundation offers Collaborative Activity Awards to initiate interdisciplinary discussions on problems or issues, to help launch interdisciplinary research networks, or to fund communities of researchers/practitioners dedicated to developing new methods, tools, and applications of basic research to applied problems.

In each case the focus of the collaborative activity must meet the program guidelines for one of the following program areas:

  • Studying Complex Systems
  • Mathematical & Complex Systems Approaches for Brain Cancer
  • Understanding Human Cognition

Deadline: Open


MARK YOUR CALENDARS

Measuring Biomarkers with Meso Scale Discovery

John Pink, PhD and Paul Hartman, MS of the Translational Research & Pharmacology Core Facility invite you to a presentation by Jim Kepka, Regional Director of Meso Scale Discovery (MSD) on Wednesday, November 14 at 12:30 pm in WRB 2-136. Light lunch will be provided.

Presentation and discussion will include:

  • Core Technology Overview
  • Assays for Cytokines, Intracellular Signaling & Metabolic markers
  • Phase-gated Process for Assay Development and QC

Please RSVP to John Hudson at jhudson@mesoscale.com or 630.547.5148. MSD offers a diverse product line of biomarker assays including many oncology-focused kits. They feature phospho-protein and intracellular signaling assay kits designed for use with whole cell lysates and others complex matrices. Clinical biomarker assays for analysis of serum, plasma and tissue culture samples are also available.

So You Want To Do Comparative Effectiveness Research? The Nuts and Bolts of CER

Registration is open for So You Want To Do Comparative Effectiveness Research? The Nuts and Bolts of CER, to be held Friday, December 14 in the WRB Auditorium. This half-day symposium will help heighten the understanding of comparative effectiveness research (CER), identify strategies to evaluate competing treatments and highlight the various research design methods available to perform CER. The course will be taught at an introductory level and is designed to provide resources for investigators to pursue future research projects. There is $25 registration fee, though this fee is waived for trainees, scholars, and K awardees.

CER is defined as the direct comparison of existing health care interventions to determine which work best for which patients and which pose the greatest benefits and harms. CER is receiving increasing importance nationally and internationally as a priority area of investigation and has led to the establishment of the Patient-Centered Outcomes Research Institute (PCORI).


NCI CANCER BULLETIN

October 30, 2012

News
Featured Article: Study Urges Caution on Source of Unrelated Donor Stem Cell Transplants

Study Looks at Terminal Cancer Patients' Expectations of Chemotherapy

Imatinib May Help Treat Aggressive Lymphoma

Researchers Identify Possible Biomarker for Early-Stage Lung Cancer

In Mice, Combining Cancer Vaccine and Low-Dose Anti-Angiogenesis Drug Shows Promise against Breast Cancer

Commentary
Building Momentum: NCI's Center for Global Health

A Conversation with Dr. Patrick Loehrer about Improving Cancer Care in Kenya

In Depth
Tackling the Complexity of Genes and Environments in Cancer

Featured Clinical Trial: Safety of Stem Cell Transplants for HIV-Positive Cancer Patients

Updates
Notes

EVENTS

calendar

November 5

Special Presentation: Research Faculty Candidate
Hasan Korkaya, DVM, PhD
Assistant Professor, Div. of Hem/Onc
University of Michigan Comprehensive Cancer Center
Topic: The IL6 Feedback Loop Regulates Breast Cancer Stem Cells and Therapeutic Resistance
11 am WRB 2-136

Sequencing Data Interest Group (SDIG)
Cheryl Thompson, PhD
Assistant Professor, Family Medicine
CWRU/UH
Topic: Identifying Biomarkers of Cancer Using Next Generation Sequencing
2:30 pm WRB 1-402

Physiology and Biophysics Seminar
Robert Edwards, MD
Professor, Neurology and Physiology
University of California- San Francisco
Topic: The Origin of Synaptic Vesicle Pools
4 pm SOM/Robbins Bldg E-501


November 6

Radiation Oncology Grand Rounds
Jennifer Dorth, MD
Assistant Professor, Section Leader, Gastrointestinal Radiation Oncology
CWRU/UH
Topic: Pancreatic Cancer
8:10 am Lerner Tower B-181

Medicine Grand Rounds
Lyndsay Harris, MD
Director, Breast Cancer Program
Professor, Div. of Hem/Onc
CWRU/UH
Topic: Personalized Medicine for Breast Cancer in Post-Genomic Era
12 pm Kulas Auditorium, Lakeside 5th Fl.


November 7

Hematology and Oncology Research Conference
Joseph Gibbons, MD
Assistant Professor, Div. of Hem/Onc
CWRU/UH
Topic: Human Subjects Protection in Cancer Research
8 am Lerner B-151

Immunology Students/Fellows Research in Progress Seminar Series
Chenyang Zhao, PhD
Research Associate, Hamilton Lab, Immunology
Cleveland Clinic
Topic: Enhanced Chemokine Expression in Mononuclear Phagocytes Undergoing Cell Stress Response Exhibits TLR Specificity
AND
Hao Zhou
Graduate Student
Li Lab, Immunology
Cleveland Clinic
Topic: Novel Mechanisms for the Regulatory Role of IRAKM in TLR Signaling
12 pm NC1-202 Cleveland Clinic

Innovative Science Discussion Group
Topic: TBD
12:15 pm WRB 3-136

Metabolomics Data and Cancer Research Interpretation
2:30-4:30 pm in WRB 1-413


November 8

Molecular Genetics Guest Speaker Seminar
Venuprasad Poojary, PhD
Assistant Professor, Oncology, Immunology & Microbiology
Wayne State University
Topic: E3 ligase Itch and Deubiquitinase Cyld Act Together to Regulate Tak1 and Inflammation
9:30 am NE1-205 Cleveland Clinic

Molecular Biology and Microbiology Seminar
Junpeng Yan, PhD
Skowronski Lab, Molecular Biology and Microbiology
CWRU
Topic: SAMHD1 Restriction and its Catalytic Activity
1 pm Wood Bldg, W203 Rottman Seminar Room

13th Annual Jerome I. Kleinerman, MD Lecture
JoAnne Flynn, PhD
Professor, Microbiology and Molecular Genetics
University of Pittsburgh
Topic: Seeing is Believing: New Insights in Tuberculosis
4 pm WRB 1-413


November 9

Hematology/Oncology Fellows Conference/Curriculum Series
Andy Parchman, MD
Fellow, Div. of Hem/Onc
CWRU/UH
AND
Santosh Rao, MD
Fellow, Div. of Hem/Onc
CWRU/UH
Topic: Cancer Biology Series: Cell Cycle
8 am Wearn 137/Breen

Taussig Cancer Institute Grand Rounds
Topic: Special Lecture- Cleveland Clinic only
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Saghi Ghaffari, MD, PhD
Associate Professor, Developmental and Regenerative Biology
Mt. Sinai Medical Center
Topic: Regulation of Hematopoietic and Leukemic Stem Cells by Longevity Factors
12 pm BRB 105

Stem Cell Biology and Regenerative Medicine Seminar
Joel Friedman, MD, PhD
Professor, Physiology and Biophysics
Albert Einstein College of Medicine
Topic: Theranostic Solutions: Targeted Delivery and Imaging Through Nanoparticle Platforms
1 pm NE1-205 Cleveland Clinic

Cancer Center Research in Progress
Christine Lee
Research Assistant, DiFeo Lab, Div. of General Medical Sciences (Oncology)
CWRU/UH
Topic: The Functional Role of miR-181a in Ovarian Cancer Progression
4 pm WRB 3-136

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Measuring Biomarkers with Meso Scale Discovery
November 14
Jim Kepka, Regional Director, Meso Scale Discovery
12:30 pm WRB 2-136
RSVP to jhudson@mesoscale.com
*Hosted by the Translational Research & Pharmacology Core Facility

ADDITIONAL UPCOMING SEMINARS & EVENTS

The Cancer Genome Atlas 2nd Annual Scientific Symposium: Enabling Cancer Research Through TCGA
November 27-28
Crystal City, Virginia
Details

American Society of Hematology (ASH) Annual Meeting
December 8-11
Atlanta, Georgia
Details

Pacific Symposium on Biocomputing 2013
January 3-7, 2013
Fairmont Orchid, Hawaii
Details


PREVIOUSLY ANNOUNCED OPPORTUNITIES

DeGregorio Foundation Award for Cancers of the Upper GI Tract
Deadline: November 5

AACR Scholar in Training Awards
Deadline: November 15

AACR Dharma Master Jiantai Innovative Grant for Lung Cancer Research
Deadline: November 20

Limited Submission: NIH Director's Early Independence Award
Internal Deadline: November 26
LOI Deadline: December 30
Full Application: January 30, 2013

Limited Submission: Rita Allen Foundation Scholars Program
Internal Deadline: November 26
External Deadline: January 25, 2013

AACR Minority Scholar in Cancer Research Award
Deadline: November 30

AACR-Thomas J. Bardos Science Education Awards for Undergraduate Students
Deadline: November 30

AACR-Women in Cancer Research (WICR) Scholar Awards
Deadline: November 30

Alex's Lemonade Stand Foundation Innovation Grants
Deadline: December 3

Conquer Cancer Foundation of ASCO Medical Student Rotation for Underrepresented Populations
Deadline: December 3

Weatherhead Institute for Family Medicine and Community Health Pilot
Deadline: December 3

DOD Breast Cancer Research Program Postdoctoral Fellowship Award
Pre-Application Deadline: December 4
Application Deadline: December 18

Alex's Lemonade Stand Foundation Epidemiology Awards
Deadline: December 17

Alex's Lemonade Stand Foundation Young Investigator Awards
Deadline: December 17

Association for Research of Childhood Cancer
Deadline: January 1, 2013

2013 CTSC Annual Pilot Grant Funding
LOI Deadline: January 15, 2013

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

NLM Grants for Scholarly Works in Biomedicine and Health (G13)(PAR-13-014)

NCI Established Investigator Award in Cancer Prevention and Control (K05)(PAR-12-065)

NCI Mentored Clinical Scientist Research Career Development Award to Promote Diversity (K08)(PAR-12-051)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.