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Case Comprehensive Cancer Center Newsletter

May 21, 2012

CASE CCC IN THE NEWS

Some Doctors Unaware of Long-term Side Effects of Cancer Care
CNN (blog) - May 19, 2012
Dr. Neal Meropol, chief of the division of hematology and oncology at University Hospitals Case Medical Center in Cleveland, Ohio, says he's ...

Melanoma Mortality Is Related to Dermatologist Density
OncLive - May 19, 2012
Jeremy S. Bordeaux, MD, director of Mohs Micrographic and Dermatologic Surgery at University Hospitals Case Medical Center, Cleveland, ...


MARK YOUR CALENDARS

Cancer Center Scientific Series: Imaging in Cancer

Please mark your calendars for the next installment of the Case CCC Scientific Series on Thursday, May 31 in BRB 105, with reception and presentations from 4-6 pm.

Jim Basilion, PhD will give an introduction and overview of the Cancer Imaging Program, followed by presentations by:

Cheryl Thompson, PhD: Variation in Breast Tissue Gene Expression by Mammographic Density
Chris Flask, PhD: Development of a platform of robust and cost-effective MRI techniques for tissue characterization in preclinical research

The presenters are reporting updates on research funded by American Cancer Society IRG Pilot Projects.

These extended conferences feature recent scientific investigation from our members, featuring presentations by investigators who received pilot funding after competitive peer review by the Cancer Center. We encourage you to attend, participate in the dialogue, and learn more about the research of your colleagues.


FUNDING OPPORTUNITIES

Caring for Carcinoid Foundation-AACR Grant for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research

The Caring for Carcinoid Foundation-AACR Grant for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research represents a joint effort to promote and support innovative cancer research. This grant is available to independent junior and senior investigators to develop and study new ideas and approaches that have direct application and relevance to carcinoid tumors or pancreatic neuroendocrine tumors. Proposed research may be in any discipline of basic, translational, clinical or epidemiological cancer research.

Deadline: June 18


ANNOUNCEMENTS

Case CCC PRMC Tissue Research Submission Template

The Case CCC PRMC Tissue Research Submission Template is available on the Case CCC website Clinical Research Portal and PRMC website. The tissue research submission template should be used for studies that involve research activities limited to archived or discarded tissue. If you have any questions about the template, please contact David Goldblatt at 216.844.5060, david.goldblatt@case.edu and/or Kristin Waite at 216.844.5537, kristin.waite@case.edu.

Manuscript Acknowledgements

Remember to acknowledge funding or services provided by the Cancer Center in your research papers and publications: "This research was supported by the Case Comprehensive Cancer Center (P30 CA43703)."

Ohio Neuro-Oncology Consortium Meeting

Drs. Jill Barnholtz-Sloan, Candece Gladson, Lisa Rogers, Steven Rosenfeld, and Andrew Sloan presented data on multiple brain tumor research efforts at the Ohio Neuro-Oncology Consortium (ONOC) meeting in Columbus, Ohio on May 7. Dr. Rogers is leading a study of metabolic syndrome and clinical outcomes for glioblastoma, using patients recruited in the Ohio Brain Tumor Study (OBTS).

Dr. Rosenfeld discussed his recent work on targeting glioma invasiveness through the use of a clinically available rho kinase inhibitor.

Dr. Barnholtz-Sloan also gave on talk on the OBTS, describing the study and what is available for research use. The OBTS is a multi-center research effort lead by Drs. Barnholtz-Sloan and Sloan, with participation from CWRU/UHCMC, Cleveland Clinic, Ohio State University and University of Cincinnati, to investigate the association between "omics", environmental factors, clinical factors and clinical outcomes for all newly diagnosed brain tumor patients.

Drs. Barnholtz-Sloan, Gladsen and Rosenfeld are on the ONOC Board of Directors, as the CWRU/UHCMC and Cleveland Clinic representatives, respectively. Additional presenters at the ONOC meeting from Case CCC were Drs. Alex Huang, James Basilion, Justin Lathia and Quinn Ostrom, MA.

Race for the Place- Join Our Team!

The Race for the Place, an event that benefits the Gathering Place, will be held Sunday, June 3 at Beachwood Place Mall. The Case CCC has created a CaseCCC Trainees team. Click here to join the team or to show your support by making a donation. Contact Lyn Haselton, Case CCC Training Program Manager, at 216.844.5375 or lyn.haselton@case.edu for more information.


NEWS FROM NIH

NIH Study Finds Sigmoidoscopy Reduces Colorectal Cancer Rates

Flexible sigmoidoscopy, a screening test for colorectal cancer that is less invasive and has fewer side effects than colonoscopy, is effective in reducing the rates of new cases and deaths due to colorectal cancer, according to research sponsored by the National Cancer Institute, part of the National Institutes of Health. In a study that spanned almost 20 years, researchers found that overall colorectal cancer mortality (deaths) was reduced by 26 percent and incidence (new cases) was reduced by 21 percent as a result of screening with sigmoidoscopy. These results appeared online, ahead of print, on May 21, 2012, in the New England Journal of Medicine, and were presented at Digestive Disease Week, a scientific conference.


NCI CANCER BULLETIN

May 15, 2012

News
Featured Article: Studies Support Expanded Role for Lenalidomide in Treating Multiple Myeloma

Low-Dose Radioactive Iodine Destroys Thyroid Tissue Left after Surgery

Sequencing Study Identifies Gene that May Contribute to Melanoma

Experimental Gene Therapy Protects Normal Cells from Toxic Effects of Chemotherapy

Also in the News: Sunburn and Indoor Tanning Still Common

In Depth
Unearthing Clues to Cancer Risk in the Aging Genome

Complex Immune-Based Cancer Treatment Shows Signs of Progress

"Rewiring" Cells to Treat an Aggressive Breast Cancer

Featured Clinical Trial: Experimental Antibody for Treatment-Resistant Liver Cancer

Updates
NIH Update

Notes

EVENTS

calendar

**All events are open to anyone interested in attending

May 21

Comparative Effectiveness Research: From All Angles
9 am - 5 pm SOM E401
Registration

Pathology Research Seminar Series
Xingjun Fan, PhD
Instructor, Pathology
CWRU
Topic: Glutathione Homeostasis in Neurodegenerative and Oxidative Stress Diseases
12 pm WRB 1-413

Skeletal Research Center
Catherine Verfaillie, MD
Professor, Medicine
Katholieke University of Leuven
Topic: Making Liver From Stem Cells
5 pm Clapp 108


May 22

Comparative Effectiveness Research: From All Angles
9 am - 5 pm SOM E401
Registration

Cancer Biology Fellow Seminar
Jennifer Liang, MD
Research Fellow, Kalady Lab, Colorectal Surgery
Cleveland Clinic
Topic: MicroRNAs as Tumor Suppressors in Methylated Colorectal Cancer
11 am NC1-202 Cleveland Clinic


May 23

Hematology and Oncology Division Research Conference
Rom Leidner, MD
Instructor, Div. of Hem/Onc
CWRU/UH
Topic: mRNA in Esophageal Adenocarcinoma
8 am Lerner Tower B-151

Immunology Invited Speaker Seminar Series
Brian Cobb, PhD
Assistant Professor, Pathology
CWRU
Topic: Host Glycosylation and the Immune Response
12 pm NC1-202 Cleveland Clinic


May 24

Special Seminar
Walter F. Baile, MD
Professor, Behavioral Science
University of Texas MD Anderson Cancer Center
Topic: Teaching Communication Skills in the Medical Setting: What Works and How Do You Do It
7:30 am Bunts Auditorium

Molecular Genetics Guest Speaker
James C. Alwine, PhD
Professor, Cancer Biology
University of Pennsylvania
Topic: Manipulation of Signaling, Stress Responses and Metabolism by Human Cytomegalovirus
9:30 am NE1-205 Cleveland Clinic

Pharmacology Seminar
Stephen Kron, MD, PhD
Professor, Molecular Genetics and Cell Biology
University of Chicago
Topic: Targeting Chromatin to Accelerate Cell Senescence: Shutting Off Cancer's Fountain of Youth
12 pm SOM W331

Stem Cell Biology and Regenerative Medicine
Craig Horbinski, MD, PhD
Assistant Professor, Pathology
University of Kentucky
Topic: Why Are IDH1 Mutations Favorable Prognostic Markers in Gliomas?
1 pm NE1-205 Cleveland Clinic

NCRM Seminar
Linheng Li, PhD
Investigator, Stowers Institute for Medical Research
Professor, Pathology and Laboratory Science
University of Kansas
Topic: Signaling and Epigenetic Regulation of Hematopoietic Stem Cells
2 pm NE1-205 Cleveland Clinic

Molecular Medicine Seminar
Yolanda Sanchez, PhD
Associate Professor, Pharmacology and Toxicology
Co-Director, Development of Novel Clinical and Translational Methodologies, SYNERGY
Dartmouth Center for Clinical and Translational Science
Topic: The Role of Checkpoint Pathways During Development and Cancer
4 pm NE1-205 Cleveland Clinic


May 25

Hematology/Oncology Fellows will resume in July.

Cancer Center Seminar Series will resume in September.

Taussig Cancer Institute Grand Rounds
Walter Baile, MD
Professor, Behavioral Science
University of Texas MD Anderson Cancer Center
Topic: Breaking Bad News: How to Survive the Difficult Conversation
8 am R3/002-003 Cleveland Clinic

Cancer Center Research in Progress Seminar
Yonghun Lee, PhD
Senior Research Associate, Schiemann Lab, Div. of General Medical Sciences-Oncology
CWRU
Topic: Fibulin-5 (FBLN5) Initiates EMT and Induces MMPs Expression Via Beta1 Integrin/EGFR/ERK Pathway
4 pm WRB 3-136

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Case CCC Scientific Series: Imaging in Cancer
May 31
Jim Basilion, PhD
Topic: Introduction
Chris Flask, PhD
Topic: Development of a platform of robust and cost-effective MRI techniques for tissue characterization in preclinical research
Cheryl Thompson, PhD
Topic: Variation in Breast Tissue Gene Expression by Mammographic Density
Reception and presentations, 4-6 pm BRB 105 (**please note change of location)

Ca-PRI Annual Meeting: Learning from Our Differences
June 5-7
InterContinental Hotel
Details

ADDITIONAL UPCOMING SEMINARS & EVENTS

Cleveland Clinic 2012 Personalized Healthcare Summit
May 31
InterContinental Hotel and Conference Center
Registration

Ninth International Conference of the Society for Integrative Oncology
October 8-10
Albuquerque, NM
Details

Biennial Science of Global Prostate Cancer Disparities conference
November 1-4
Nassau, The Bahamas
Details


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

DOD Lung Cancer Research Program Idea Development Award
Pre-Application Deadline: May 30
Application Deadline: September 20

DOD Lung Cancer Research Program Translational Research Partnership Award
Pre-Application Deadline: May 30
Application Deadline: September 20

Doctors Cancer Foundation, Inc.
Deadline: May 31

Damon Runyon-Rachleff Innovation Award
Deadline: June 1

DOD Prostate Cancer Research Program Exploration - Hypothesis Development Award
Pre-Application Deadline: June 6
Application Deadline: June 20

DOD Prostate Cancer Research Program Physician Research Training Award
Pre-Application Deadline: June 6
Application Deadline: June 20

DOD Prostate Cancer Research Program Postdoctoral Training Award
Pre-Application Deadline: June 6
Application Deadline: June 20

DOD Peer Reviewed Cancer Research Program Visionary Postdoctoral Fellowship Award
Pre-Application Deadline: June 19
Application Deadline: September 12

DOD Peer Reviewed Cancer Research Program Career Development Award
Pre-Application Deadline: June 19
Application Deadline: September 12

AACR-Prevent Cancer Foundation Award for Excellence in Cancer Prevention Research
Deadline: June 20

AACR Award for Distinguished Lecture on the Science of Health Disparities, funded by Susan G. Komen for the Cure®
Deadline: June 20

Mesothelioma Applied Research Foundation
Deadline: July 6

Society of Surgical Oncology Clinical Investigator Award in Breast Cancer Research
Deadline: July 9

Alex's Lemonade Stand Foundation Nursing Grants Program Explorer Awards
Deadline: August 1

Alex's Lemonade Stand Foundation Nursing Grants Program Pathfinder Award: Intermediate Nurse Researcher Grants
Deadline: August 1

Alex's Lemonade Stand Foundation Nursing Grants Program Discovery Award: Independent Nurse Researcher Grants
Deadline: August 1

DOD Prostate Cancer Research Program Health Disparity Research Award
Pre-Application Deadline: July 26
Application Deadline: August 9

International Myeloma Foundation Brian D. Novis Senior Research Award
Deadline: August 1

International Myeloma Foundation Brian D. Novis Junior Research Award
Deadline: August 1

Szent-Györgyi Prize for Progress in Cancer Research
Deadline: September 30

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Notice of Change in Participation of NIH Institutes and Centers in PAS-12-169 Limited Competition: Revision Applications to Advance Evidence-Based Research Related to Protections for Human Subjects (U54)(NOT-OD-12-105)

Notice of Termination of PAR-10-280, Limited Competition for the Global Research Initiative Program, Behavioral/Social Sciences (GRIP/BSS) Research Award (R01)(NOT-TW-12-009)

Exploratory/Developmental Clinical Research Grants in Obesity (R21)(PA-12-179)

Native American Research Centers for Health (NARCH)(PAR-12-182)

Final Weeks to Register for NIH Regional Seminar on Program Funding and Grants Administration in Washington, D.C. - June 20-22, 2012(NOT-OD-12-109)

Notice of NIH Piloting of Procedures for Special Council Review of Research Applications from PD(s)/PI(s) with More than $1.5 Million Total Annual NIH Support (NOT-OD-12-110)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.