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Case Comprehensive Cancer Center Newsletter

March 26, 2012

CASE CCC IN THE NEWS

Cleveland Clinic Looking for Funding to Study Breast Cancer Vaccine in Humans
MedCity News - Mar 20, 2012
Clinic immunologist Vincent Tuohy made a splash about two years ago, when his research on the vaccine was published in the journal Nature Medicine.

CyberKnife Radiosurgery of the Prostate
MD News - Mar 20, 2012
Dr. Lee Ponsky is director, Urologic Oncology Center, University Hospitals Urology Institute, UH Case Medical Center, and the Leo & Charlotte Goldberg Chair ...

Leukemia Studies Show Promise for Less-toxic, More-effective Treatment
Plain Dealer - Mar 20, 2012
You want the porridge just right," said Dr. Hillard Lazarus, director of the Blood and Marrow Transplantation Program at the Seidman Cancer Center...Most therapeutic agents today are not selective," said Anthony Berdis, assistant professor of pharmacology ...


ANNOUNCEMENTS

ASC Silber Fellowships Discontinued

The American Cancer Society Silber Fellowship was discontinued this year due to financial constraints. The ACS will continue its commitment to cancer research by focusing resources on raising funds for beginning investigators, advocating for funding at the federal level, and increasing awareness about the progress being made by researchers.

AACR Annual Meeting

The American Association for Cancer Research (AACR) Annual Meeting will be held March 31-April 4 in Chicago.

A number of Cancer Center members will be participating, including the following major presenters:

Gregory E. Plautz
Faculty, Educational Session: Cancer Immunology for the Non-Immunologist – Tutorial
Mar 31; 10:00 AM - 12:00 PM McCormick Place West (Level 1), Room W180

James P. Basilion
Presenter, Defining the cutting edge
Major Symposium: Molecular Imaging in Cancer Therapy: Functionalizing the Cancer Genome
Apr 2; 11:30 - 11:55 AM McCormick Place West (Level 1), Room W184

Sanford D. Markowitz
Chairperson, Current Concepts and Controversies in Organ Site Research: The Epigenome/Genome in Colorectal Cancer: From Discovery to Therapeutics
Apr 3; 10:30 AM - 12:30 PM McCormick Place West (Level 1), Room W190

Presenter, Genetic opportunities for cancer detection and prevention
Current Concepts and Controversies in Organ Site Research: The Epigenome/Genome in Colorectal Cancer: From Discovery to Therapeutics
Apr 3; 11:45 AM - 12:05 PM McCormick Place West (Level 1), Room W190

Charis Eng
Chairperson, Current Concepts and Controversies in Organ Site Research: Mechanisms of Hereditary Cancer: Beyond the Tumor Suppressor Paradigm
Apr 4; 11 AM -1 PM McCormick Place West (Level 1), Room W181

Presenter, Germline epimutations: More than the genome
Current Concepts and Controversies in Organ Site Research: Mechanisms of Hereditary Cancer: Beyond the Tumor Suppressor Paradigm
Apr 4; 11:50 AM - 12:10 PM McCormick Place West (Level 1), Room W181

 

A list of poster presentations is available on our website.


MARK YOUR CALENDARS

Cancer Center Seminar Series: New Treatment for Chronic Lymphocytic Leukemia (CLL)
Dr. Byrd

Friday, March 30
12 pm
BRB 105

Please join us March 30 for the next Cancer Center Seminar Series where Dr. John C. Byrd, D. Warren Brown Chair of Leukemia Research and Director of the Division of Hematology at The Ohio State University, will present New Treatment for Chronic Lymphocytic Leukemia (CLL).

Dr. John C. Byrd is a nationally known researcher and clinical specialist in leukemia and other hematologic malignancies at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC-James), where he is co-leader of the Innate Immunity research program and a member of the Experimental Therapeutics research program at the OSUCCC-James.

Dr. Byrd's research accomplishments relate best to translational studies with several therapeutic agents that are active against chronic lymphocytic leukemia (CLL) and related leukemias and lymphomas. As a consequence of his detailed laboratory and clinical work, therapeutic agents such as rituximab, alemtuzumab and recently flavopiridol have been identified as effective agents against CLL. Dr. Byrd strives to develop therapeutic antibodies and other targeted agents against hematologic malignancies because of his desire to offer patients non-toxic therapies with fewer side effects.

Informatics Symposium

Register today for Informatics: Driving Discovery, Improving Health (IDD 2012), April 6 in the Wolstein Research Building. This symposium, sponsored by CWRU and Clinical and Translational Science Collaborative (CTSC), brings together all the disciplines involved in clinical and translational research for the shared benefits of networking and education.

Symposium themes will focus on the application and impact of information technology, such as:

  • Informatics for Integrating Biology and the Bedside
  • Electronic Health Record Facilitated Enterprise Performance Management
  • Multi-Modality, Multi-Resource Information Integration Environment for Multi-center Physiological and Clinical Research Studies
  • Grid and Cloud Platforms for Translational Informatics and Data Management

A discounted registration rate of $30 is available for students and CTSC/Cancer Center members.

Case CCC Scientific Series

Please mark your calendars for the next installments of the Case CCC Scientific Series:

Stem Cells
April 12
Reception and presentations, 4-6 pm BRB 105
Alex Huang, MD: Longitudinal tracking of in vivo tumor microenvironment in high definition
Jeongwu Lee, PhD: C-MET signaling in GBM stem cells and treatment resistance
Ofer Reizes, PhD: Obesity tips the scales on breast cancer: a role for the fat hormone leptin in cancer stem cells

Imaging Research
May 31
Reception and presentations, 4-6 pm WRB 1-413
Jim Basilion, PhD: Introduction
Chris Flask, PhD: Development of PARACEST-MRI Imaging Agents for In Vivo Assessment of Autophagy OR Magnetic Resonance Imaging as an Early-Stage Biomarker
Cheryl Thompson, PhD: Variation in Breast Tissue Gene Expression by Mammographic Density

These extended conferences feature recent scientific investigation from our members, featuring presentations by investigators who received pilot funding after competitive peer review by the Cancer Center. Please make every effort to attend.


FUNDING OPPORTUNITIES

Prostate Cancer Research Program

Applications for the Prostate Cancer Research Program (PCRP) are being solicited by the Assistant Secretary of Defense for Health Affairs, Defense Health Program:

  • The PCRP Biomarker Development Award mechanism is being offered for the first time in FY12. The intent of this award is to support the near-term translation of prostate cancer biomarkers to clinical practice.
    Pre-Application Deadline: May 3
    Application Deadline: August 23
  • The PCRP Clinical Exploration Award mechanism is being offered for the first time in FY12. The intent of this award is to support early-phase, proof-of-principle clinical trials and correlative studies to investigate hypothesis-based, innovative interventions and/or avenues of research that have the potential to resolve current clinical barriers and result in a profound impact on the management of prostate cancer.
    Pre-Application Deadline: May 3
    Application Deadline: August 23
  • The PCRP Health Disparity Research Award supports new ideas based on innovative concepts or methodologies for prostate cancer health disparity research with the potential to make an important contribution towards eliminating death and suffering from prostate cancer.
    Pre-Application Deadline: July 26
    Application Deadline: August 9
  • The PCRP Laboratory - Clinical Transition Award supports product-driven preclinical studies of promising lead agents or medical devices that have the potential to revolutionize prostate cancer clinical care.
    Pre-Application Deadline: May 3
    Application Deadline: August 23
  • The PCRP Transformative Impact Award supports prostate cancer research with near-term clinical relevance that will transform and revolutionize the clinical management of prostate cancer, to include the wide spectrum of screening, detection, diagnosis, prognosis, and/or treatment), and have a major impact on the elimination of death and suffering from prostate cancer.
    Pre-Application Deadline: May 3
    Application Deadline: August 23
  • The PCRP Exploration - Hypothesis Development Award supports the exploration of highly innovative, untested, potentially high-gain concepts, theories, paradigms, and/or methods that address an important problem in prostate cancer.
    Pre-Application Deadline: June 6
    Application Deadline: June 20
  • The PCRP Idea Development Award supports new ideas that represent innovative approaches to prostate cancer research and have the potential to make an important contribution to eliminating death and suffering from prostate cancer.
    Pre-Application Deadline: April 24
    Application Deadline: August 9
  • The PCRP Synergistic Idea Development Award supports new ideas that represent innovative approaches to prostate cancer research involving two or three independent, faculty-level (or equivalent) Principal Investigators (PIs).
    Pre-Application Deadline: May 3
    Application Deadline: August 9
  • The PCRP Physician Research Training Award supports a mentored training experience to prepare physicians with clinical duties and/or responsibilities for productive careers in prostate cancer research.
    Pre-Application Deadline: June 6
    Application Deadline: June 20
  • The PCRP Postdoctoral Training Award supports prostate cancer research training opportunities for recent doctoral graduates.
    Pre-Application Deadline: June 6
    Application Deadline: June 20

EVENTS

calendar

**All events are open to anyone interested in attending

March 26

SDIG Meeting
Ricky Chan, PhD
Post Doctoral Research Fellow, Genomic Medicine Institute
Cleveland Clinic
Topic: Genome Sequencing of Plasmodium Vivax Isolates
2:30 pm WRB 1-402


March 27

Pharmacology Seminar
Mark Levine, MD
Chief, Molecular and Clinical Nutrition Section
Senior Staff, NIH
Topic: Adventures at C: Physiology and Pharmacology Discoveries, Promise in Cancer Treatment
12 pm SOM W331


March 28

Hematology and Oncology Division Research Conference
Elizabeth Weinstein, MD
Div. of Hem/Onc
CWRU/UH
Topic: TBD
8 am Lerner Tower B-151

Immunology Faculty Research in Progress Seminar
Harold Hoffman, MD
Associate Professor, Pediatrics and Medicine
University of California, San Diego
Topic: Inflammasome Mediated Diseases in Man and Mouse
12 pm NC1-202 Cleveland Clinic


March 29

Grant Writing and Reviewing Workshop
Alan L. Willard, PhD
Deputy Director, Division of Extramural Research
NIH/NINDS
Topic: Writing and Reviewing Grants: Negotiating the NIH Grant System
10 am - 12 pm WRB 1-413

Cancer Center Faculty Candidate Seminar
Kwon-Sik Park, PhD
Postdoctoral Fellow, Pediatrics and Genetics
Stanford University
Topic: Role of Developmental Pathways in Lung Cancer
1 pm WRB 3-136

Grant Writing and Reviewing Workshop
Alan L. Willard, PhD
Deputy Director, Division of Extramural Research
NIH/NINDS
Topic: Job Opportunities in Health Research Administration at the NINDS
1 pm WRB 1-413

Molecular Biology and Microbiology Seminar
Serendipity Zapanta Rinonos
Tartakoff Lab
CWRU
Topic: Zygotes Defy Stereotypes: Polarity Determinants in the Haploid-to-Diploid Transition
AND
Alan Tartakoff, PhD
Professor, Pathology
CWRU
Topic: Conclusions of the Cell Cycle in Yeast
1 pm SOM W203

Stem Cell Biology and Regenerative Medicine Seminar
David Gutmann, MD, PhD
Donald O. Schnuck Family Professor
Director, Neurofibromatosis Program
St. Louis Children's Hospital
Topic: What Cancer Can Teach Us About Neural Stem Cells
1 pm NE1-205 Cleveland Clinic


March 30

Cancer Center Research in Progress Seminar cancelled

Hematology/Oncology Fellows
Ken Cooke, MD
Associate Professor, Pediatric Hem/Onc
CWRU/UH
Topic: BMT
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
John Heymach, MD, PhD
Associate Professor, Thoracic/Head and Neck Medical Oncology- Cancer Medicine
University of Texas MD Anderson Cancer Center
Topic: Markers and Mechanisms of Resistance for VEGF Inhibitors
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
John C. Byrd, MD
D. Warren Brown Chair of Leukemia Research
Director, Division of Hematology
The Ohio State University
Topic: New Treatment for Chronic Lymphocytic Leukemia (CLL)
12 pm BRB 105

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Case CCC Clinical Research Retreat
April 4
5:30-8:30 pm Dively Building
Agenda
Registration

Breast Cancer 2012: Risk Assessment through Survivorship
May 18
Brochure
Registration

Ca-PRI Annual Meeting: Learning from Our Differences
June 5-7 InterContinental Hotel
Details

ADDITIONAL UPCOMING SEMINARS & EVENTS

Department of Biomedical Engineering Special Seminar
May 3
Steve Zullo, PhD
Program Director, Division of Discovery Science and Technology
National Institute of Biomedical Imaging and Bioengineering, NIH
Topic: NIH Grant Machine Revealed, Not a Black Box Anymore
12 pm Wickenden 509


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Multiple Myeloma Research Foundation 2012 Senior Research Award Program
Deadline: March 27

National CENter for ReGenerAtive Medicine UnderGraduate StudEnt (ENGAGE) Summer Program
Deadline: March 30

Irvington Institute Fellowship Program
Deadline: April 1

American Cancer Society Postdoctoral Fellowships
Deadline: April 1

Clinical and Translational Informatics Funding Opportunity
Deadline: April 2

DAISY Foundation 2012 Patient Care Research Grant Program for Nurses
LOI Deadline: April 2
Application Deadline: June 8

Specialized Program of Research Excellence in Gastrointestinal Malignancies (GI SPORE)
Deadline: April 2

DOD Breast Cancer Research Program Postdoctoral Fellowship Award
Pre-Application Deadline: April 5
Application Deadline: April 19

DOD Breast Cancer Research Program Era of Hope Award
Pre-Application Deadline: April 5
Application Deadline: April 19

DOD Ovarian Cancer Research Program Pilot Award
Pre-Application Deadline: April 9
Application Deadline: July 18

SU2C-CRI Cancer Immunology Translational Research Dream Team
LOI Deadline: April 9

DOD Peer Reviewed Medical Research Program Investigator-Initiated Research Award
Pre-Application Deadline: April 10
Application Deadline: July 31

DOD Ovarian Cancer Research Program Ovarian Cancer Academy Award
Pre-Application Deadline: April 17
Application Deadline: July 18

DOD Ovarian Cancer Research Program Synergistic Translational Leverage Award
Pre-Application Deadline: April 17
Application Deadline: July 18

DOD Ovarian Cancer Research Program Teal Innovator Award
Pre-Application Deadline: April 17
Application Deadline: July 18

DOD Breast Cancer Research Program Idea Award Award
Pre-Application Deadline: April 26
Application Deadline: August 15

American Nurses Foundation Nursing Research Grants
Deadline: May 1

Howard Hughes Medical Institute Investigator Program
Deadline to establish eligibility: May 1
Application Deadline: June 13

DOD Breast Cancer Research Program Impact Award
Pre-Application Deadline: May 3
Application Deadline: August 15

DOD Breast Cancer Research Program Innovator Award Award Award
Pre-Application Deadline: May 3
Application Deadline: August 2

DOD Breast Cancer Research Program Clinical Translational Research Award
Pre-Application Deadline: May 3
Application Deadline: August 15

DOD Breast Cancer Research Program Transformative Vision Award
Pre-Application Deadline: May 3
Application: August 15

Barrett's Esophagus Translational Research Network (BETRNet) pilot projects
Deadline: May 18

Doctors Cancer Foundation, Inc.
Deadline: May 31

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Translational Research at the Aging/Cancer Interface (TRACI) (R01)(PA-12-136)

Translational Research at the Aging/Cancer Interface (TRACI) (R21)(PA-12-135)

Pilot and Feasibility Clinical Research Studies in Digestive Diseases and Nutrition (R21)(PA-12-139)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.