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Case Comprehensive Cancer Center Newsletter

February 27, 2012

CASE CCC IN THE NEWS

The Miracle of Modern Medicine
Youngstown Vindicator - Feb 26, 2012
It was just his moment," said Dr. Nathan Pennell, Hiznay's thoracic oncologist. Between Sept. 1 and 21, an amazing confluence of events – his mother, ...

More Melanoma Deaths in Areas Without Dermatologists: Study
Reuters - Feb 23, 2012
Earlier studies have found that people who have more family physicians and pediatricians nearby live longer, said Dr. Jeremy Bordeaux, a dermatologist at ...

Higher Dermatologist Level, Lower Melanoma
UPI.com - Feb 22, 2012
Savina Aneja of Case Western Reserve University in Cleveland and colleagues examined data on melanoma mortality rates per 100000 people from January 2002 to ...

7 Steps for Building a Top-Tier Cancer Center
Becker's Hospitals Review - Feb 21, 2012
...One of the keys to a successful cancer center is having several teams that specialize in a specific type of cancer, according to Nathan Levitan, MD, president of the University Hospitals Seidman Cancer Center in Cleveland...


MARK YOUR CALENDARS

Cancer Center Seminar Series: Mechanisms Regulating Stress Erythropoiesis– Understanding a New Adult Stem Cell Population
Dr. Lynch

Friday, March 2
12 pm
BRB 105

Please join us Friday, March 2 for the next Cancer Center Seminar Series where Dr. Robert F. Paulson, Associate Professor of Veterinary and Biomedical Sciences at Penn State University, will present Mechanisms Regulating Stress Erythropoiesis– Understanding a New Adult Stem Cell Population.

Dr. Paulson's work focuses on the mechanisms that regulate stress erythropoiesis. Steady state erythropoiesis constantly generates new erythrocytes to maintain homeostasis. However, at times of acute blood loss, steady state erythropoiesis is unable to keep pace with erythropoietic need. At these times, stress erythropoiesis predominates. Steady state erythropoiesis occurs primarily in the bone marrow, but stress erythropoiesis is extramedullary. Using a murine system, Dr. Paulson has developed a new model for stress erythropoiesis. His work showed that stress erythropoiesis utilizes a novel population of stress erythroid progenitors, which respond to signals distinct from those that regulate bone marrow steady state erythropoiesis. In addition, his work identified a self-renewing stress erythroid progenitor that is capable of establishing a durable stress erythroid compartment when transplanted into irradiated mice. Dr. Paulson will present his latest work on characterizing this system and discuss the state of what is known about stress erythropoiesis in humans.


FUNDING OPPORTUNITIES

DOD Breast Cancer Research Program

Applications for the Breast Cancer Research Program (BCRP) are being solicited by the Assistant Secretary of Defense for Health Affairs, Defense Health Program:

  • The Postdoctoral Fellowship Award supports exceptionally talented recent doctoral or medical graduates in their pursuit of innovative, high-impact breast cancer research during their postdoctoral training and allows them to obtain the necessary experience for an independent career at the forefront of breast cancer research. These individuals should be exceptionally talented scientists who have demonstrated that they are the "best and brightest" of their peers. Applicants for this award must exhibit a strong desire to pursue a career in breast cancer research.
    Pre-Application Deadline: April 5
    Application Deadline: April 19
  • The Idea Award Award is designed to promote new ideas that are still in the early stages of development and have the potential to yield highly impactful data and new avenues of investigation. This mechanism supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress toward ending breast cancer. Applications should include a well-formulated, testable hypothesis based on strong scientific rationale.
    Pre-Application Deadline: April 26
    Application Deadline: August 15
  • The Impact Award supports research projects (from small- to large-scale) that specifically focus on scientific and clinical breast cancer issues, which, if successfully addressed, will revolutionize the understanding, prevention, and/or treatment of breast cancer and make major advances toward the goal of ending the disease. The BCRP particularly encourages applications that focus on poorly understood issues that are of critical significance in breast cancer, such as those related to prevention, susceptibility, recurrence, or metastasis. The proposed work must be based on sound overall research and fully supported by preliminary data and/or published reports.
    Pre-Application Deadline: May 3
    Application Deadline: August 15
  • The Era of Hope Award supports individuals who are early in their careers and have high potential for innovation in breast cancer research. These individuals should be exceptionally talented scientists who have demonstrated that they are the "best and brightest" in their field(s) through extraordinary creativity, vision, and productivity. They should have demonstrated experience in forming effective partnerships and collaborations and should exhibit strong potential for leadership in the breast cancer research community.
    Pre-Application Deadline: April 5
    Application Deadline: April 19
  • The Innovator Award Award Award supports visionary individuals who have demonstrated creativity, innovative work, and leadership in any field including, but not limited to, breast cancer. The Innovator Award will provide these individuals with the funding and freedom to pursue their most novel, visionary, high-risk ideas that could ultimately lead to ending breast cancer.
    Pre-Application Deadline: May 3
    Application Deadline: August 2
  • The Clinical Translational Research Award is intended to promote significant improvements over current approaches to breast cancer prevention and therapy, such as studies that will prevent primary or recurrent breast cancer and studies that may result in a new treatment to prevent breast cancer progression to metastasis. The CTR Award supports research projects that are likely to have a major impact on breast cancer by applying promising research findings to patients with, or populations at risk for, breast cancer.
    Pre-Application Deadline: May 3
    Application Deadline: August 15
  • The Transformative Vision Award supports research projects that will fulfill an extraordinary vision for dramatically affecting the prevention or treatment of breast cancer. This award requires a plan that will test and achieve the vision as quickly as possible through the translation of the research ideas to individuals with, and/or those at risk for, breast cancer. The scope of the effort may include a broad spectrum of research spanning from basic to clinical studies.
    Pre-Application Deadline: May 3
    Application: August 15

NCI CANCER BULLETIN

February 21, 2012

News
Breaking News: FDA Acts to Bolster Supply of Critical Cancer Drugs

Featured Article: Routine Lynch Syndrome Screening Varies at U.S. Cancer Centers

Contrary to Evidence, Some Doctors Recommend Ovarian Cancer Screening

Lynch Syndrome Tied to Increased Risk of Breast and Pancreatic Cancers

Radiation Therapy after Surgery for Lung Cancer May Not Improve Survival

High Platelet Levels Linked with Poor Survival in Ovarian Cancer

In Depth
Profiles in Cancer Research: Dr. Gordon Hager

Featured Clinical Trial: Surgical Removal of Primary Tumor for Metastatic Breast Cancer

Clinical Trials Network Aims to Strengthen Cancer Immunotherapy Pipeline

Updates
Notes

EVENTS

calendar

**All events are open to anyone interested in attending

February 27

SDIG Meeting
Olivia Corradin
PhD student, Genetics
CWRU
Topic: Utilization of RNA-seq and ChIP-seq Data for the Identification of Enhancers and Their Targets
2:30 pm WRB 1-402


February 28

Cancer Biology Invited Speaker Seminar
Brian Strahl, PhD
Associate Professor and Director of Graduate Studies, Department of Biochemistry and Biophysics
University of North Carolina at Chapel Hill
Topic: Using Peptide Microarrays to Interrogate the Histone Code
11 am NC1-202 Cleveland Clinic

Molecular Biology and Microbiology Seminar
George Drusano, MD
Director, Institute for Therapeutic Innovation
University of Florida
Topic: TB Therapy: Do We Really Know What We are Doing?
1 pm SOM W203


February 29

Hematology and Oncology Division Research Conference
Stanton Gerson, MD
Shiverick Professor of Hematological Oncology
Director, Case Comprehensive Cancer Center
Director, Seidman Cancer Center
Topic: How Drugs Kill Cancer: Something New About Antifolates
8 am Lerner Tower B-151

Department of Neurosciences Guest Speaker Series
James Basilion, PhD
Associate Professor, Radiology, Biomedical Engineering and Pathology
CWRU
Topic: Defining the Cutting Edge
10 am NE1-205 Cleveland Clinic

Frontiers in Molecular Medicine
Michael Hemann, PhD
Associate Professor, Biology
Koch Institute for Integrative Cancer Research
Massachusetts Institute of Technology
Topic: Strategies for Pool-based RNAi Screening
11 am WRB 1-413

Immunology Faculty Research in Progress Seminar Series
Wink Baldwin, PhD
Staff, Immunology
Cleveland Clinic
Topic: Antibody Responses to Transplants: Controlling Divergent Outcomes
12 pm NC1-202 Cleveland Clinic

Frontiers in Molecular Medicine
Michael Hemann, PhD
Associate Professor, Biology
Koch Institute for Integrative Cancer Research
Massachusetts Institute of Technology
Topic: Using In Vivo RNAi to Investigate Drug Action and Chemotherapeutic Resistance
4 pm WRB 1-413


March 1

Cancer Center Faculty Candidate
Wei Qiu, PhD
Research Instructor, Pathology
University of Pittsburgh Hillman Cancer Center
Topic: Mechanisms of Intestinal Stem Cell Survival
1 pm WRB 3-136


March 2

Hem/Onc Fellows Conference
Topic: TBD
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Lilyana Angelov, MD
Staff, Brain Tumor and Neuro-Oncology Center
Cleveland Clinic
Topic: The Role of Stereotactic Radiosurgery in the Management of Metastatic Spine Tumors
AND
Ping Xia, PhD
Professor, Radiation Oncology
CWRU/Cleveland Clinic
Topic: Topic: Update in Medical Physics
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Robert F. Paulson, PhD
Associate Professor, Veterinary and Biomedical Sciences
Penn State University
Topic: Mechanisms Regulating Stress Erythropoiesis– Understanding a New Adult Stem Cell Population
12 pm BRB 105

Cancer Center Research in Progress Seminar Cheng-Kui Qu, MD, PhD
Associate Professor, Medicine-Hem/Onc
CWRU/UH
Topic: A Bioenergetic Checkpoint for Hematopoietic Stem Cell Differentiation
4 pm WRB 3-136

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Ca-PRI Annual Meeting: Learning from Our Differences
June 5-7 InterContinental Hotel
Details

ADDITIONAL UPCOMING SEMINARS & EVENTS

NCI Second Symposium on Translational Genomics
March 15-16
NIH, Bethesda, Maryland
Registration

Midwest Blood Club Symposium
March 15-16
Indiana University School of Medicine
Details

Sternlicht Memorial Lectureship in Cancer Biology and Pharmacology
March 22
Gordon Shore, PhD
Professor, Biochemistry
McGill University
Topic: Targeting Mcl-1 for Synthetic Lethality in Cancer Therapy
4 pm WRB 1-413

Department of Biomedical Engineering Special Seminar
May 3
Steve Zullo, PhD
Program Director, Division of Discovery Science and Technology
National Institute of Biomedical Imaging and Bioengineering, NIH
Topic: NIH Grant Machine Revealed, Not a Black Box Anymore
12 pm Wickenden 509


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

NSF Integrative Graduate Education and Research Traineeship Program (IGERT)
Internal Deadline: February 27

Robert Wood Johnson Foundation Clinical Scholars Program
Deadline: February 29

Cancer Research Institute Student Training and Research in Tumor Immunology (STaRT) Program
Deadline: March 1

New York Academy of Medicine David E. Rogers Fellowship Program
Deadline: March 1

Leukemia & Lymphoma Society Translational Research Program
LOI Deadline: March 1
Full Application Deadline: March 15

Robert Wood Johnson Foundation: Building Evidence for Decision-Making
Mandatory LOI Deadline: March 6
Application Deadline: March 27

Childhood Brain Tumor Foundation (CBTF)
Deadline: March 12

James S. McDonnell Foundation Research Award in Brain Cancer Research
Deadline: March 14

James S. McDonnell Foundation Scholar Awards in Complex Systems Science
Deadline: March 14

Alex's Lemonade Stand Pediatric Oncology Student Training (POST) Program
Deadline: March 15

Damon Runyon Cancer Research Foundation Fellowship Award
Deadline: March 15

Damon Runyon-Sohn Pediatric Cancer Fellowship Award
Deadline: March 15

American Society of Hematology(ASH) Trainee Research Award
Deadline: March 16

Prostate Cancer Foundation-Honorable A. David Mazzone Special Challenge Award Research Program 2012
Deadline: March 16

American Legacy Foundation Sybil G. Jacobs Award for Outstanding Use of Tobacco Industry Documents
Deadline: March 23

American Legacy Foundation Christine O. Gregoire Youth/Young Adult Award for Outstanding Use of Tobacco Industry Documents
Deadline: March 23

Multiple Myeloma Research Foundation 2012 Senior Research Award Program
Deadline: March 27

National CENter for ReGenerAtive Medicine UnderGraduate StudEnt (ENGAGE) Summer Program
Deadline: March 30

Irvington Institute Fellowship Program
Deadline: April 1

American Cancer Society Postdoctoral Fellowships
Deadline: April 1

Clinical and Translational Informatics Funding Opportunity
Deadline: April 2

DAISY Foundation 2012 Patient Care Research Grant Program for Nurses
LOI Deadline: April 2
Application Deadline: June 8

American Nurses Foundation Nursing Research Grants
Deadline: May 1

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Research on the Health of LGBTI Populations [R01](PA-12-111)

Research on the Health of LGBTI Populations [R03](PA-12-112)

Research on the Health of LGBTI Populations (R21)(PA-12-113)

Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (Parent T32)(PA-11-184)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.