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Case Comprehensive Cancer Center Newsletter

February 6, 2012

CASE CCC IN THE NEWS

Prostate Cancer Radiation is Expensive
dailyRx - Feb 9, 2011
Lead author and Cleveland Clinic Radiation Oncologist, Jay Ciezki, MD stated, "We were able to get a good picture of the long-term costs of patient care and ...

Calif. Clinic Licensed by Controversial Stem Cell Treatment Group
California Watch - Feb 1, 2012
George F. Muschler, an orthopedic surgeon and professor at Case Western ... Muschler found faults with the reports' methodology, scope and oversight, ...


MARK YOUR CALENDARS

Cancer Center Seminar Series: Advancing Immune Cell Therapies Through Imaging
Dr. Contag

Friday, February 10
12 pm
BRB 105

Please join us Friday, February 10 for the next Cancer Center Seminar Series where Dr. Christopher H. Contag, Professor and Associate Chief of Pediatrics– Neonatal & Developmental Medicine and Microbiology & Immunology at Stanford University, will present Advancing Immune Cell Therapies Through Imaging.

Imaging enables the in vivo study of cell biology, and when integrated with thorough studies in culture and ex vivo analyses, can reveal the nuances of disease mechanisms and of subtlety of therapeutic responses.

Visible animal models of human biology and disease comprise one of the most important contributions of molecular imaging to human health as they serve to accelerate and refine the analyses of mammalian biology and offer rapid readouts for the development of new therapies. Dr. Contag's lab has developed imaging approaches based on optical reporter genes and have used them to reveal immune cell trafficking patterns, regulation of gene expression, extent of tumor growth, stem cell biology, and nature of host responses to infection. Recently, his lab revealed the kinetics of stem cell engraftment and hematopoietic reconstitution, elucidated the nature of minimal residual disease states following cancer therapy, and identified tissue sites that pathogens use to evade the host immune response.

Research Best Practices Day 2012

Registration is now open for Research Best Practices Day 2012, February 22 from 9 am - 4 pm in the Wolstein Research Building Auditorium. This annual event is open to the entire research community. Each year, several topics are presented by local experts as part of CWRU's ongoing training in the Responsible Conduct of Research (RCR). A session on NIH public access policy compliance has been added to the day's agenda. Faculty, staff and students are encouraged to attend one or more of the sessions that are applicable to their research:

  • The Nuts and Bolts of Research Documentation
  • Communication and Collaboration in Research: Tips and Tactics for Investigators, Students and Staff to Enhance Integrity in Research
  • Commercializing Research: Working with the Technology Transfer Office
  • Complying with the NIH Public Access Policy: From Soup to Nuts (newly added)
  • Animal Research: Working Effectively with IACUC
NIDDK Workshop: Regulatory Determinants of Hematopoietic Stem Cell Differentiation and Terminal Development: New Insights

On February 20, the Hematology Program of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the NIH will host a one day workshop on Regulatory Determinants of Hematopoietic Stem Cell Self-Renewal, Lineage Commitment and Terminal Differentiation: New Insights. This "state-of-the-science" workshop will take place at the American Institute of Architects building in Washington, DC. The objectives of the workshop are to provide an opportunity for research leaders in the field of hematopoietic stem cell (HSC) biology to review and discuss current understanding of how HSC self-renewal, lineage commitment, and terminal differentiation are regulated, to define knowledge gaps and key unanswered questions in these critical aspects of HSC biology, and to define opportunities, directions, and priorities for future research that will address these questions. The program will include presentations by both invited speakers and speakers selected from submitted abstracts, together with poster presentations.

A limited number of travel grants will be made available to registrants whose abstracts are selected for oral presentation at the workshop. Space at the workshop will be limited, and so early registration is encouraged. Registrants who submit abstracts for presentation at the workshop will be given preference if the number of registrants exceeds available space.


NEWS FROM NIH

New Website: NIH Clinical Research Trials and You

The National Institutes of Health has created a new website, NIH Clinical Research Trials and You to help people learn more about clinical trials, why they matter, and how to participate.

Visitors to the website will find information about:

  • The basics of clinical trial participation
  • First hand experiences from actual clinical trial volunteers
  • Explanations from researchers
  • Links on how to search for a trial or enroll in a research matching program

In addition, health care professionals can read about evidence-based strategies for talking with patients about trials, print audience-tested posters to help promote trials in clinics and offices, and find other educational materials.


FUNDING OPPORTUNITIES

Alex's Lemonade Stand Pediatric Oncology Student Training (POST) Program

Alex's Lemonade Stand Pediatric Oncology Student Training (POST) Program is for graduate and medical students interested in pursuing a career in pediatric oncology research. Students select a mentor in the field of pediatric oncology research to continue their training throughout the summer months. The project may be ongoing research in the mentor's lab or original and does not need to be completed in the program period.

Deadline: March 15

Multiple Myeloma Research Foundation Senior Research Award

The Multiple Myeloma Research Foundation (MMRF) seeks proposals for the 2012 Senior Research Award Program, an initiative supporting researchers who have more than five years experience in blood cancer research. The goal of this initiative is to accelerate the development of therapeutic approaches for myeloma and may include proposals in basic science or translational research.

Deadline: March 27

Damon Runyon Cancer Research Foundation Fellowship Award

The Damon Runyon Cancer Research Foundation is accepting applications for the Fellowship Award. The Foundation encourages all theoretical and experimental research relevant to the study of cancer and the search for cancer causes, mechanisms, therapies and prevention.

Candidates must apply for the fellowship under the guidance of a Sponsor–a scientist (tenured, tenure-track or equivalent position) capable of providing mentorship to the Fellow. In addition to aiding in the planning, execution and supervision of the proposed research, the Sponsor's role is to foster the development of the Fellow's overall knowledge, technical and analytical skills, and capacity for scientific inquiry. The Sponsor is also expected to assist the Fellow in attaining his/her career goals.

Deadline: March 15


ANNOUNCEMENTS

Dissecting Scope Needed

The Markowitz lab is looking for a dissecting scope that someone might have that is not in active use. Please contact Dr. Sandy Markowitz with any information.

Summer Volunteers: Placements Needed

It's that of year again where we receive requests from students inquiring about summer research positions. Currently, we need a place for one student who has an interest in bone cancer, but is open to a position in any area. If you are willing to take this student or any summer student, please send an email to Lyn Haselton, Cancer Center Training Program Manager. We will add your name to a list and will send you resumes if we receive them.

EVENTS

calendar

**All events are open to anyone interested in attending

February 6

Immunology Seminar Series
Yang Liu, PhD
Charles B. de Nancrède Research Professor in Surgery
Co-leader of Cancer Immunology Program, University of Michigan Comprehensive Cancer Center
Topic: Self-nonself Discrimination in Innate Immunity: Implications for Infection, Cancer and Autoimmune Diseases
12 pm WRB 1-413

Physiology and Biophysics Seminar
Jeffrey Abramson, PhD
Associate Professor, Molecular Physiology and Biophysics
University of California at Los Angeles
Topic: Crystal Structures of vSGLT: Reveal Mechanism of Na+/Sugar Cotransport
4 pm SOM E501

Cancer Imaging Program Meeting
William Schiemann, PhD
Associate Professor, General Medical Sciences-Oncology
CWRU
Topic: Problems and Solutions for Imaging in Cancer
4:30 pm Wearn B37


February 7


February 8

Hematology and Oncology Division Research Conference
Alvin Schmaier, MD
Professor, Div. of Hem/Onc
CWRU/UH
Topic: Novel Mechanisms for Arterial Thrombosis
8 am Lerner Tower B-151

Immunology Invited Speaker Seminar Series
Leslie Berg, PhD
Professor, Pathology
University of Massachusetts
Topic: The Tec Kinase ITK Regulates T Cell Lineage Determination
12 pm NC1-202 Cleveland Clinic


February 9

Stem Cell Biology and Regenerative Medicine Seminar
Matthew Kalady, MD
Assistant Professor, Surgery
CWRU/Cleveland Clinic
Topic: From Genetics to Stem Cells: Moving Towards Personalized Care in Colorectal Cancer
1 pm NE1-205 Cleveland Clinic

Case Cell Biology Program Seminar: The 2011 Science Nobel Prizes - What Were They Given For?
Glenn Starkman, PhD: Physics Prize
Man-Sun Sy, PhD: Physiology or Medicine Prize
Arthur Heuer, PhD: Chemistry Prize
4:15 pm Rockefeller 301


February 10

Cancer Center Research in Progress Seminar canceled

Hem/Onc Fellows Conference
Santosh Rao, MD
Fellow, Div. of Hem/Onc
CWRU/UH
Topic: TBD
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Robert Dean, MD
Associate Staff, Hematologic Oncology & Blood Disorders
Cleveland Clinic
Topic: What's New in Transplantation for Lymphoma
AND
Kevin Stephans, MD
Associate Staff, Radiation Oncology
Cleveland Clinic
Topic: Stereotactic Radiation for Liver Malignancies
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Christopher H. Contag, PhD
Professor and Associate Chief, Pediatrics - Neonatal & Developmental Medicine and Microbiology & Immunology
Stanford University
Topic: Advancing Immune Cell Therapies Through Imaging
12 pm BRB 105

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Cancer Cell Signaling Program Retreat
February 29
6-8 at the College Club
RSVP to Tracy Rehl at tracy.rehl@case.edu

ADDITIONAL UPCOMING SEMINARS & EVENTS

NCI Second Symposium on Translational Genomics
March 15-16
NIH, Bethesda, Maryland
Registration

Department of Biomedical Engineering Special Seminar
May 3
Steve Zullo, PhD
Program Director, Division of Discovery Science and Technology
National Institute of Biomedical Imaging and Bioengineering, NIH
Topic: NIH Grant Machine Revealed, Not a Black Box Anymore
12 pm Wickenden 509


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Innovations for Health: Solutions that Cross Borders
Deadline: February 13

Advancing Health Services through System Modeling Research
Deadline: February 15

Leukemia Research Foundation New Investigator Grants
Deadline: February 15

Ohio Cancer Research Associates
Deadline: February 17

NSF Integrative Graduate Education and Research Traineeship Program (IGERT)
Internal Deadline: February 27

Robert Wood Johnson Foundation Clinical Scholars Program
Deadline: February 29

Cancer Research Institute Student Training and Research in Tumor Immunology (STaRT) Program
Deadline: March 1

New York Academy of Medicine David E. Rogers Fellowship Program
Deadline: March 1

Leukemia & Lymphoma Society Translational Research Program
LOI Deadline: March 1
Full Application Deadline: March 15

Childhood Brain Tumor Foundation (CBTF)
Deadline: March 12

James S. McDonnell Foundation 21st Century Research Awards
Deadline: March 14

Damon Runyon-Sohn Pediatric Cancer Fellowship Award
Deadline: March 15

American Society of Hematology(ASH) Trainee Research Award
Deadline: March 16

Prostate Cancer Foundation-Honorable A. David Mazzone Special Challenge Award Research Program 2012
Deadline: March 16

American Legacy Foundation Sybil G. Jacobs Award for Outstanding Use of Tobacco Industry Documents
Deadline: March 23

American Legacy Foundation Christine O. Gregoire Youth/Young Adult Award for Outstanding Use of Tobacco Industry Documents
Deadline: March 23

National CENter for ReGenerAtive Medicine UnderGraduate StudEnt (ENGAGE) Summer Program
Deadline: March 30

Irvington Institute Fellowship Program
Deadline: April 1

American Cancer Society Postdoctoral Fellowships
Deadline: April 1

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Correction: RFA-AI-12-002 Limited Competition - Women's Interagency HIV Study (WIHS-V)(U01)

PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

PHS 2012-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])(PA-12-089)

New Technologies for Viral Hepatitis SBIR (R43/R44)(PA-12-090)

New Technologies for Viral Hepatitis STTR (R41/R42)(PA-12-091)

Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities (R21)(PAR-12-094)

Basic Cancer Research in Cancer Health Disparities (U01)(PAR-12-095

Exploratory Grant Award to Promote Workforce Diversity in Basic Cancer Research (R21)(PAR-12-096)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.