Case Comprehensive Cancer Center: Weekly Newsletter

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January 3, 2012
CASE CCC IN THE NEWS Mammograms Go 3-D KSDK - Jan 2, 2011 Tomosynthesis allows radiologist Donna Plecha to get a more detailed view. Instead of the standard four images from the x-ray, she's seeing about 200. ... Cleveland Clinic Researcher Discovers Genetic Cause of Thyroid Cancer HealthCanal.com - Dec 27, 2011 Research led by Charis Eng, MD, PhD, Chair and founding Director of the Genomic Medicine Institute of Cleveland Clinic's Lerner Research Institute, ... Skin Cancer More Likely After First Malignancy MedPage Today - Dec 20, 2011 ... 45 and older after a first primary cancer, Jeremy S. Bordeaux, MD, MPH, of University Hospitals Case Medical Center in Cleveland, and colleagues found. ... Breast Cancer Awareness All Year: NetWellness Plain Dealer - Dec 20, 2011 This week's NetWellness column is by Dr. Paula Silverman, associate professor of Medicine, School of Medicine, Case Western Reserve University There are ... Healing From Cancer Tops Family's Christmas List Guilford County Northwest Observer - Dec 16, 2011 "There has been significant progress in the treatment of glioblastoma," says Andrew Sloan, MD, director of the Brain Tumor and Neuro-oncology Center at University Hospitals Case Medical Center in Cleveland... MARK YOUR CALENDARS Special Cancer Center Seminar Series: RB-pathway in Translation: Significance to Breast Cancer Treatment Tuesday, January 3 4-5 pm Wolstein Research Building 2-136 Please join us today, January 3, at 4 pm in Wolstein 2-136 for a special seminar titled RB-pathway in Translation: Significance to Breast Cancer Treatment, presented by Erik Knudsen, PhD. Dr. Knudsen is the Deputy Director for Basic Research at the Kimmel Cancer Center and Professor of Cancer Biology at Thomas Jefferson University. He has made significant contributions to our understanding of tumor suppressor function, with particular emphasis on RB in various cancers. Most recently, he has delineated a role for RB in regulating therapeutic responsiveness of breast cancer. Among his many accomplishments are membership on the Editorial Board for "Cancer Research" and he has recently chaired the Tumor Cell Biology Study Section. He has also published over 100 primary research articles. In his seminar, Dr. Knudsen will share his most recent insights regarding the use of RB status as a predictor for therapeutic response in breast cancer. NCI Second Symposium on Translational Genomics Registration is now open for the Second Symposium on Translational Genomics, March 15-16 at the NIH in Bethesda, Maryland. Presented by the NCI Center of Excellence in Integrative Cancer Biology and Genomics, this seminar will provide a dedicated forum for the advancement, implementation, and exchange of information on noncoding RNAs, next generation sequencing, and epigenomics and genetic variation for translation into clinical practice, with the ultimate goal to improve the health of patients with cancer. NEWS FROM THE NIH NIH Establishes National Center for Advancing Translational Sciences In a move to re-engineer the process of translating scientific discoveries into new drugs, diagnostics, and devices, the National Institutes of Health has established the National Center for Advancing Translational Sciences (NCATS). The action was made possible by Congress' approval of a fiscal year 2012 spending bill and the president's signing of the bill, which includes the establishment of NCATS with a budget of $575 million. NCATS will serve as the nation's hub for catalyzing innovations in translational science. Working closely with partners in the regulatory, academic, nonprofit, and private sectors, NCATS will strive to identify and overcome hurdles that slow the development of effective treatments and cures. ANNOUNCEMENTS New Members Please join us in welcoming the newest members of the Case CCC: Ramon Tiu, MD Assistant Professor, Translational Hematology and Oncology Research Hematopoietic Disorders Program Carl Tyler, MD Associate Professor, Family Medicine Cancer Prevention, Control and Population Research Program Vikas Gulani, MD, PhD Assistant Professor, Radiology Cancer Imaging Program Efstathios Karathanasis, PhD Assistant Professor, Biomedical Engineering and Radiology Cancer Imaging Program Justin Lathia, PhD Research Associate, Stem Cell Biology and Regenerative Medicine Cancer Cell Signaling Program Sonja Harris-Haywood, MD Assistant Professor, Family Medicine Cancer Prevention, Control and Population Research Program Cancer Center Members Recognized for Contributions to Science and Technology by AAAS In November 2011, 539 individuals were elected as Fellows of the American Association for the Advancement of Science (AAAS). The Case CCC is honored to have three researchers from our institutions recognized for their contributions to science and technology: Xiaoxia Li and Michael Lederman for Medical Sciences and Bruce Lamb for Neuroscience. FUNDING OPPORTUNITIES American Society of Clinical Oncology (ASCO) Conquer Cancer Foundation Annual Meeting Merit Awards The Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO) offers Merit Awards to trainees who submit high-quality abstracts selected for presentation at an ASCO Meeting. To be considered for a Merit Award, the first author of an abstract must be a physician (MD, PharmD, PhD, DO, or other doctoral degree) enrolled in an oncology training program at the time of abstract submission, work in an oncology laboratory or clinical research setting, and agree to present the abstract at the ASCO Annual Meeting. Candidates must apply for this award at the time of abstract submission. Deadline: February 1 Damon Runyon-Sohn Pediatric Cancer Fellowship Award The Damon Runyon Cancer Research Foundation has joined together with the Sohn Conference Foundation, dedicated to curing pediatric cancers, to establish the Damon Runyon-Sohn Pediatric Cancer Fellowship Award. This award provides funding to basic scientists and clinicians who conduct research with the potential to significantly impact the prevention, diagnosis or treatment of one or more pediatric cancers. Only one fellowship application will be accepted from a Sponsor or Fellow per review session; there is no limit, however, to the number of applications from an institution. Deadline: March 15	EVENTS *All events are open to anyone interested in attending January 2 Happy New Year!* January 3 Special Cancer Center Seminar Series Erik Knudsen, PhD Deputy Director for Research Professor, Cancer Biology Kimmel Cancer Center/Thomas Jefferson University Topic: RB-pathway in Translation: Significance to Breast Cancer Treatment 4 pm WRB 2-136 January 4 Hematology and Oncology Division Research Conference Paula Silverman, MD Associate Professor, Div. of Hem/Onc CWRU/UH AND Ashley Rosko, MD Fellow, Div. of Hem/Onc CWRU/UH AND Lan Zhou, MD, PhD Assistant Professor, Pathology CWRU/UH Topic: Addressing Systematic Errors and Delays: A Case Discussion 8 am Lerner Tower B-151 January 5 Molecular Biology & Microbiology Seminar Susann Brady-Kalnay, PhD Professor, Molecular Biology & Microbiology CWRU Topic: PTPmu as a Therapeutic Target in Brain Tumors AND Susan Burden-Gulley, PhD Senior Research Associate, Brady-Kalnay Lab, Molecular Biology & Microbiology CWRU Topic: Molecular Imaging of Dispersing Brain Tumor Cells 1 pm Rottman Seminar Rm. W203 January 6 Cancer Center Seminar Series canceled Hem/Onc Fellows Conference Anita Schwandt, MD Fellow, Div. of Hem/Onc CWRU/UH Topic: TBD 8 am Wearn 137 Taussig Cancer Institute Grand Rounds Mellar Davis, MD Professor, Hematology & Medical Oncology CWRU/Cleveland Clinic Topic: Fatigue in Cancer: What are the Mechanisms? AND Patrick Ma, MD Assistant Professor, Translational Hematology and Oncology Research CWRU/Cleveland Clinic Topic: MET Targeting Personalized Lung Cancer Therapy 8 am R3/002-003 Cleveland Clinic CAP Promotion Seminar Takao Sakai, PhD Assistant Professor, Biomedical Engineering CWRU/Cleveland Clinic Topic: Interdependence of Cell and Extracellular Matrix on Adult Tissue Repair 11 am NA1-142 Cleveland Clinic Cancer Center Research in Progress Seminar Molly Taylor Graduate Student, Schiemann Lab, Div. of General Medical Sciences-Oncology CWRU/UH Topic: The Role of microRNA-181a in TGF-beta Mediated Breast Cancer Progression 4 pm WRB 3-316 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS Special Seminar January 19 Jacques Galipeau, MD, FRCP(C) Professor, Hematology and Medical Oncology & Pediatrics Emory University Winship Cancer Institute Topic: Mesenchymal Stromal Cell Suppression of Autoimmune Response. From Discovery to Design of Cell Therapy Studies 12 pm Wearn 137 ADDITIONAL UPCOMING SEMINARS & EVENTS Berman Lecture/Department of Medicine Grand Rounds January 17 Max Wicha, MD Director, University of Michigan Comprehensive Cancer Center Distinguished Professor of Oncology Professor, Internal Medicine University of Michigan Topic: Clinical Implications of Cancer Stem Cells 12 pm Kulas Auditorium Department of Biomedical Engineering Special Seminar May 3 Steve Zullo, PhD Program Director, Division of Discovery Science and Technology National Institute of Biomedical Imaging and Bioengineering, NIH Topic: NIH Grant Machine Revealed, Not a Black Box Anymore 12 pm Wickenden 509



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
ASCO Resident Travel Award Deadline: January 9 Society of Surgical Oncology 2012 Clinical Investigator Awards Deadline: January 9 AACR-Genentech BioOncology Fellowship for Cancer Research on the HER Family Pathway Deadline: January 10 AACR Judah Folkman Career Development Award for Antiangiogenesis Research Deadline: January 10 American Brain Tumor Association (ABTA) Deadline: January 10 Beez Foundation Deadline: January 10 Lymphatic Research Foundation (LRF) Postdoctoral Fellowship Program Deadline: January 10 AACR Clinical and Translational Cancer Research Fellowships Deadline: January 11 HHMI Medical Research Fellows Program Deadline: January 11 SAIC-Frederick Support of the Cancer Genome Atlas Program Deadline: January 13 CTSC Annual Pilot Grant Funding Mandatory LOI Deadline: January 15 Oncology Nursing Society Foundation Connie Henke Yarbro Excellence in Cancer Nursing Mentorship Award Deadline: January 15 Caring for Carcinoid Foundation-AACR Grants for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research Deadline: January 17 Fight Colorectal Cancer-AACR Career Development Award, in memory of Lisa Dubow Deadline: January 17 Landon Foundation-AACR INNOVATOR Award for International Collaboration in Cancer Research Deadline: January 18 Landon Foundation-AACR INNOVATOR Award for Research in Personalized Cancer Medicine Deadline: January 18 Robert Wood Johnson Foundation Executive Nurse Fellows Deadline: January 18 Children's Tumor Foundation Young Investigator Award Program Pre-Application Deadline: January 27 Application Deadline: April 2 Sarcoma Foundation of America (SFA) Deadline: January 31	2012 Lasker Awards Deadline: February 1 Oncology Nursing Foundation Deadline: February 1 Lymphatic Research Foundation (LRF) Additional Support for NIH-funded F32 Postdoctoral Fellows Deadline: February 3 Innovations for Health: Solutions that Cross Borders Deadline: February 13 Advancing Health Services through System Modeling Research Deadline: February 15 Ohio Cancer Research Associates Deadline: February 17 Robert Wood Johnson Foundation Clinical Scholars Program Deadline: February 29 Leukemia & Lymphoma Society Translational Research Program LOI Deadline: March 1 Full Application Deadline: March 15 Childhood Brain Tumor Foundation (CBTF) Deadline: March 12 James S. McDonnell Foundation 21st Century Research Awards Deadline: March 14 Irvington Institute Fellowship Program Deadline: April 1 Wendy Will Case Cancer Fund Deadline: April 1 Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC) Deadline: Open AACR Scholar-in-Training Awards - Other Conferences and Meetings Deadline: Open Case CCC Protocol Specific Research Support (PSRS) Deadline: Open International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program Application Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities Small Grants for Behavioral Research in Cancer Control (R03)(PAR-12-035) The NCI Transition Career Development Award to Promote Diversity (K22)(PAR-12-062) NCI Established Investigator Award in Cancer Prevention and Control (K05)(PAR-12-065) Cancer Prevention, Control, Behavioral Sciences, and Population Sciences Career Development Award (K07)(PAR-12-067) Fogarty HIV Research Training Program for Low- and Middle-Income Country Institutions (D43)(PAR-12-068) Early-Stage Innovative Technology Development for Cancer Research (R21) (RFA-CA-12-002) Validation and Advanced Development of Emerging Technologies for Cancer Research (R33)(RFA-CA-12-003) Innovative and Early-Stage Development of Emerging Technologies in Biospecimen Science (R21)(RFA-CA-12-004) Validation and Advanced Development of Emerging Technologies in Biospecimen Science (R33)(RFA-CA-12-005) Notice of Two Pilot Processes for Submitting Administrative Supplement Requests Electronically to NIH (NOT-OD-12-024) Innovative Molecular Analysis Technologies (IMAT) for Cancer Research Selection of Appropriate Funding Opportunity (NOT-CA-12-006) Extension of Expiration Date for NCI Funding Opportunity Announcement PAR-09-089: The NCI Transition Career Development Award (K22) (NOT-CA-12-010)
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216-844-8317 phone 216-844-7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.