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Case Comprehensive Cancer Center Newsletter

December 12, 2011

CASE CCC IN THE NEWS

UH Seidman Cancer Center Researchers Present Findings at American Society of Hematology Annual Meeting
MarketWatch (press release) - Dec 11, 2011
"The breadth and depth of this innovative cancer research presented at ASH is truly outstanding," says Stan Gerson, MD, Director of the Seidman Cancer ...

North Coast Cancer Joins Clinic
Cleveland Jewish News - Dec 8, 2011
... look forward to enhancing the excellent clinical care that North Coast can offer," said Dr. Brian J. Bolwell, chairman of the Taussig Cancer Institute. ...

Pfizer Kidney Cancer Drug Gets FDA Panel's Nod
Wall Street Journal - Dec 8, 2011
Speaking for Pfizer, Brian I. Rini, MD, from the Taussig Cancer Institute at the Cleveland Clinic in Ohio, presented the latest data from the phase 3 Axis ...Mikkael Sekeres, MD, MS, from the Taussig Cancer Institute admitted that his yes vote was reluctant...

Cleveland Clinic Oncologist Recognized for Kidney Cancer Drug Research
The Plain Dealer - Dec 8, 2011
Dr. Brian Rini led the AXIS 1032 study, which was the first to conduct a head-to-head comparison of two kidney cancer drugs.

Peregrine's Lung Cancer Drug Has Promising Trial
Seeking Alpha - Dec 7, 2011
... all types of cancer," said Dr. Neal Meropol of University Hospitals Case Medical Center in Cleveland, who has long used Avastin for colon cancer. ...

Aplastic Anemia & MDS International Foundation Announces Treating MDS Toolkit, a New Resource for Health Care Providers
Sacramento Bee - Dec 6, 2011
The toolkit was developed in response to the results of an MDS patient survey conducted in 2009 by AAA&MDSIF and led by Mikkael A. Sekeres, MD, ...

Addition to UH Geauga Medical Center to Provide Integrated Cancer Care
News-Herald.com - Dec 5, 2011
"As part of the long-range planning for Seidman, we thought there needed to be a presence of radiation oncology in Geauga County," said Dr. Louis Novak, ..."The expansion of our cancer program at UH Geauga Medical Center offers exceptional advantages to Geauga County residents," said Dr. Nathan Levitan, ...

University Hospitals is World Winner for Digital Radiological Imaging Storage, Recovery Solutions
EurekAlert (press release) - Dec 5, 2011
Accepting it for UH were Jeffrey Sunshine, MD, Ph.D., Vice Chairman, Department of Radiology, and Vice President and Chief Medical Information Officer; ...


MARK YOUR CALENDARS

Cancer Center Seminar Series: Chasing Oncogene Addiction into the Clinic
Khuri

Friday, December 16
12-1 pm
Frohring Auditorium - BRB 105

Please join us Friday, December 16 at the next Cancer Center Seminar Series featuring Fadlo R. Khuri, MD, Deputy Director of the Winship Cancer Institute, Chair and Professor of Hematology and Medical Oncology and the Roberto C. Goizueta Distinguished Chair in Cancer Research at Emory University. Dr. Khuri will present Chasing Oncogene Addiction into the Clinic.

Dr. Khuri is an active member of the American Association for Cancer Research, American Society of Clinical Oncology, and the International Association for the Study of Lung Cancer. Dr. Khuri authored more than 180 articles for peer-reviewed journals. He serves on the editorial board for "Cancer", "Journal of Clinical Oncology", "Clinical Cancer Research", and "American Journal of Clinical Oncology", and reviews manuscripts for these and several other journals.

Dr. Khuri's research interests include development of molecular, prognostic, therapeutic, and chemopreventive approaches to improve the standard of care for patients with tobacco related cancers. His group is investigating the mechanism of action of signal transduction inhibitors in lung and head and neck cancers.


ANNOUNCEMENTS

Brian Rini Kidney Cancer Drug Research Recognized in ASCO Annual Report

Research related to the AXIS 1032 study, led by Dr. Brian Rini, was featured in the American Society of Clinical Oncology (ASCO) Annual Clinical Care Advances Report, which summarizes the most important advances in clinical cancer research over the past year. Prior to this study, though there were several drugs approved to treat metastatic kidney cancer, those drugs had only been tested against placebos. This was the first trial comparing two kidney cancer drugs against each other.

Clinical Cancer Advances 2011: ASCO's Annual Report on Progress Against Cancer was published last week in the "Journal of Clinical Oncology". In this year's report, ASCO outlines 54 of the most significant advances on the front lines of cancer research over the past year, including 12 major clinical advances in such key areas as prevention and screening, personalized medicine and targeted therapies, new treatments and medications for specific diseases, reducing cancer recurrence, and more.

Newly Released Treating MDS Toolkit Based on Survey Led by Mikkael Sekeres

The Aplastic Anemia & MDS International Foundation (AA&MDSIF) is pleased to announce the launch of the Treating MDS Toolkit, a new, free resource developed for health care providers to communicate with and support their patients with myelodysplastic syndromes (MDS). The toolkit contents are based on the needs identified by MDS patients in the survey conducted by AA&MDSIF and led by Dr. Mikkael Sekeres. The survey results, which were summarized in "The Oncologist" earlier this year, showed that patients with MDS have a limited understanding of their disease characteristics, prognosis, and treatment goals, and thus may not be prepared to discuss disease-modifying therapies. Dr. Jaroslaw Maciejewski also assisted with the publication.

OnCore Clinical Trials Management System Training Classes

Starting in 2012, OnCore training classes will be held quarterly. Each class will be held from 12-1 pm in Wearn 137, and will cover a different topic in the OnCore database:

  • January 18, 2012: General Info/Navigation, Searches, Home Screen Personalization
  • April 18, 2012: Documents Tab of Main Console
  • July 18, 2012: Reviews Tab of Main Console
  • October 17, 2012: CRA Console/Subject Administration

The last 15-20 minutes of class will be an open session to answer specific questions. Feel free to bring your lunch. Participation is open and encouraged for anyone new or old to OnCore. One-on-one training sessions are available as needed. Contact April Firstencel (216-286-2294 or april.firstencel@case.edu) with any questions.


FUNDING OPPORTUNITIES

NSF Partnerships for Innovation Program

The NSF Partnerships for Innovation (PFI) program is an umbrella for two complementary subprograms: one of which involves an earlier stage that focuses on building innovation capacity and the other involves a later stage that focuses on the acceleration of innovative research. Limit of ONE application per organization.
Internal Deadline: December 14
External LOI Deadline: January 4, 2012

ASCO Resident Travel Award

The ASCO Resident Travel Award, funded by Susan G. Komen for the Cure®, provides financial support for residents from underrepresented populations to attend ASCO's Annual Meeting. The intention of this award is to attract residents from underrepresented populations to a possible career in one of the oncology specialties. This travel award will allow the recipients to travel to the 2012 ASCO Annual Meeting, where they will have an opportunity to meet oncologists and to understand the career possibilities in this area.
Deadline: January 09, 2012

AACR Judah Folkman Career Development Award for Antiangiogenesis Research

The AACR Judah Folkman Career Development Award for Antiangiogenesis Research represents a joint effort to encourage and support junior faculty who are in the first four years of a faculty appointment (at the start of the grant term) to conduct cancer research and establish successful career paths in this field.
Deadline: January 10, 2012

Landon Foundation-AACR INNOVATOR Award for International Collaboration in Cancer Research

The Landon Foundation-AACR INNOVATOR Award for International Collaboration in Cancer Research will support highly meritorious research that is being conducted collaboratively by investigators in different countries around the world. The goals of the program are to overcome barriers to international collaboration by providing funding for costs traditional grant mechanisms may not support; raise the profile of the importance of collaboration to conquering the cancer problem; and provide the means to facilitate travel and the sharing of knowledge that otherwise may have been difficult to achieve.
Deadline: January 18, 2012

Sarcoma Foundation of America

The Sarcoma Foundation of America (SFA) has developed a program to provide grants to investigators interested in translational science Sarcoma research. Funding is available in support of research on the etiology, molecular biology, pathogenesis, diagnosis, and treatment of human Sarcomas. In accordance with the mission of the Foundation, research involving the development of novel agents against Sarcoma, or research that could potentially lead to the development of novel agents against Sarcoma, is eligible for this funding. Preference will be given to proposals on promising molecular targets and new or uncommon therapeutic approaches.
Deadline: January 31, 2012

Oncology Nursing Foundation

The Oncology Nursing Foundation is offering scholarships to registered nurses who are interested in and committed to oncology nursing to continue their education by pursuing a research doctoral degree (PhD or DNSc) or clinical doctoral degree (DNP).
Deadline: February 1, 2012

Lymphatic Research Foundation Postdoctoral Fellowship Program

The Lymphatic Research Foundation (LRF) Postdoctoral Fellowship Program is designed to support postdoctoral scientists in academic, medical or research institutions throughout the world. The awards will support investigators who have recently received their doctorates, a critical point in career development when young scientists choose their lifelong research focus. The goal of the Fellowship Program is to expand and strengthen the pool of outstanding junior investigators in the field of lymphatic research.
Deadline: February 3, 2012

Ohio Cancer Research Associates

Ohio Cancer Research Associates has released a call for applications for research funding to support research activities broadly related to cancer and leukemia. The organization seeks to fund research that will lead to continued support at the national level.
Deadline: February 17, 2012

Childhood Brain Tumor Foundation

The Childhood Brain Tumor Foundation (CBTF) is soliciting grant applications for research related to pediatric brain tumors. All proposed studies must have the approval of the proposing institution's Institutional Review Board (if appropriate) at the time of funding. Two grant applications will be selected for funding from special set-aside funds. One study will be selected for a low-grade astrocytoma/juvenile pilocytic astrocytoma and the other for Atypical Teroid/Rhabdoid Tumor.
Deadline: March 12, 2012

Irvington Institute Fellowship Program of the Cancer Research Institute

The Irvington Institute Fellowship Program of the Cancer Research Institute, answers the need for more researchers in the field of cancer immunology. It supports qualified young scientists at leading universities and research centers around the world who wish to receive training in cancer immunology.
Deadline: April 1, 2012

Wendy Will Case Cancer Fund

The Wendy Will Case Cancer Fund is accepting applications for research funding. The purpose of this fund is to support promising researchers and help them establish track records.
Deadline: April 1, 2012

EVENTS

calendar

**All events are open to anyone interested in attending

December 12

Physiology and Biophysics Seminar
Bruce Bean, PhD
Professor, Neurobiology
Harvard University
Topic: Spontaneous Electrical Activity of Mammalian Central Neurons
12 pm SOM E501

SDIG Meeting
Shuying Sun, PhD
Assistant Professor, General Medical Sciences (Oncology)
CWRU
Topic: Quality Assessment of Methylation Sequencing Data and a New Hidden Markov Model Based Method for Identifying Differential Methylation Regions
2:30 pm WRB 1-402


December 13

Immunology Seminar Series
Galit Alter, PhD
Assistant Professor, Medicine
Massachusetts Institute of Technology and Harvard University
Topic: Learning to Manipulate the Antibody Glycan
12 pm WRB 1-413


December 14

Hematology and Oncology Division Research Conference
Mitchell Machtay, MD
Professor and Chair, Radiation Oncology
CWRU/UH
Topic: Stage III Non-small Cell Lung Cancer
8 am Lerner Tower B-151

Immunology Seminar
Vincent Tuohy, PhD
Professor, Immunology
CWRU/ Cleveland Clinic
Topic: Optimizing Prophylactic Breast Cancer Vaccination
12 pm NC1-202 Cleveland Clinic

LRI Showcase Seminar
Alex Almasan, PhD
Associate Professor, Cancer Biology, Radiation Oncology
CWRU/Cleveland Clinic
Topic: Autophagy: a Therapeutic Challenge in Tumor Cells
4:30 pm NE1-205 Cleveland Clinic


December 15

TGFβ Focus Group meeting canceled

Tumor Microenvironment and Metastasis Focus Group meeting canceled

NCRM & Stem Cell Biology and Regenerative Medicine Seminar
Patrick Paddison, PhD
Assistant Member, Human Biology Division
Fred Hutchinson Cancer Research Center
Topic: The Occupy Brain Cancer Movement: Functional Genetics in the Patient-Derived Glioblastoma Multiforme Stem Cells
1 pm NE1-205 Cleveland Clinic

Special Presentation: Hematology and Oncology Research Conference
Brent A. Hanks, MD, PhD
Hematology and Oncology Fellow
Duke University Medical Center
Topic: Loss of the Type III TGF-beta Receptor During Cancer Progression Generates an Immunotolerant Tumor Microenvironment: Translational Implications for TGF-beta Inhibition Therapy and Immunotherapy Biomarker Development
1:30 pm WRB 2-136


December 16

Hem/Onc Fellows Conference
Tycel Phillips, MD
Fellow, Div. of Hem/Onc
CWRU/UH
Topic: Phase III Study to Evaluate Temsirolimus Compared With Investigator's Choice Therapy for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
8 am Wearn 137

Taussig Cancer Institute Grand Rounds Damir Janigro, MD
Professor, Neurosurgery
CWRU/Cleveland Clinic
Topic: Markers of Blood Brain Barrier Function and Their Use for Metastatic Brain Tumor Detection
AND
Samuel Chao, MD
Assistant Professor, Brain Tumor and Neuro-oncology, Radiation Oncology
CWRU/Cleveland Clinic
Topic: Update on CNS Radiation Oncology
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Fadlo R. Khuri, MD
Deputy Director, Winship Cancer Institute
Chair and Professor, Hematology and Medical Oncology
Roberto C. Goizueta Distinguished Chair in Cancer Research
Ermory University
Topic: Chasing Oncogene Addiction into the Clinic
12 pm BRB 105

Cancer Center Research in Progress Seminar
Konstantin Leskov, PhD
Senior Research Scientist, Stearns Lab
CWRU/UH
Topic: 15-Hydroxyprostaglandin Dehydrogenase (15-PGDH) Contains Dachshund Homology Domain and Regulates Gene Transcription
4 pm WRB 3-136

 

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

ADDITIONAL UPCOMING SEMINARS & EVENTS


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

AACI Translational Cancer Research Fellowship
Internal Deadline: December 12
External Deadline: February 1, 2012

NIH Director's Transformative Research Awards
LOI Deadline: December 12
Application Deadline: January 12, 2012

Mary Kay Foundation Translational Cancer Research Program
Internal Deadline: December 13
External Deadline: February 3, 2012

Damon Runyon Clinical Investigator Award
Internal Deadline: December 14
External Deadline: February 12, 2012

L'Oréal USA Fellowships For Women In Science
Deadline: December 15

National Center of Regenerative Medicine (NCRM)Stem Cell-related Pilot Projects
Deadline: December 21

Society of Surgical Oncology 2012 Clinical Investigator Awards
Deadline: January 9, 2012

AACR-Genentech BioOncology Fellowship for Cancer Research on the HER Family Pathway
Deadline: January 10, 2012

Beez Foundation
Deadline: January 10, 2012

Lymphatic Research Foundation (LRF) Postdoctoral Fellowship Program
Deadline: January 10, 2012

AACR Clinical and Translational Cancer Research Fellowships
Deadline: January 11, 2012

HHMI Medical Research Fellows Program
Deadline: January 11, 2012

SAIC-Frederick Support of the Cancer Genome Atlas Program
Deadline: January 13, 2012

CTSC Annual Pilot Grant Funding
Mandatory LOI Deadline: January 15, 2012

Oncology Nursing Society Foundation Connie Henke Yarbro Excellence in Cancer Nursing Mentorship Award
Deadline: January 15, 2012

Caring for Carcinoid Foundation-AACR Grants for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research
Deadline: January 17, 2012

Fight Colorectal Cancer-AACR Career Development Award, in memory of Lisa Dubow
Deadline: January 17, 2012

Robert Wood Johnson Foundation Executive Nurse Fellows
Deadline: January 18, 2012

Children's Tumor Foundation Young Investigator Award Program
Pre-Application Deadline: January 27, 2012
Application Deadline: April 2, 2012

2012 Lasker Awards
Deadline: February 1, 2012

Innovations for Health: Solutions that Cross Borders
Deadline: February 13, 2012

Advancing Health Services through System Modeling Research
Deadline: February 15, 2012

Robert Wood Johnson Foundation Clinical Scholars Program
Deadline: February 29, 2012

Leukemia & Lymphoma Society Translational Research Program
LOI Deadline: March 1, 2012
Full Application Deadline: March 15, 2012

James S. McDonnell Foundation 21st Century Research Awards
Deadline: March 14, 2012

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Clarification of NOT-MH-12-001 - Notice of Availability of Administrative Supplements for U.S. - Russia Collaborative HIV/AIDS Research (NOT-MH-12-011)

Pre-Application Teleconference for RFA-RM-11-022 - Integrated Microphysiological Systems for Drug Efficacy and Toxicity Testing in Human Health and Disease (UH2/UH3) and RFA-RM-12-001 Stem/Progenitor Cell-Derived Human Micro-organs and -tissues (U18) (NOT-RM-12-007)

Notice of Termination of PAR-10-278, Limited Competition for the Global Research Initiative Program, Basic/Biomedical Sciences (R01) (NOT-TW-12-003)

Notice of Termination of PAR-11-037, Limited Competition: Fogarty International Research Collaboration - Basic Biomedical (FIRCA-BB) Research Award (R03) (NOT-TW-12-004)

Limited Competition: Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54) (PAR-12-055)

Radiological/Nuclear Medical Countermeasure Product Development Program (SBIR[R43/R44])(PA-12-044)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.