Case Comprehensive Cancer Center: Weekly Newsletter

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November 7, 2011
CASE CCC IN THE NEWS Charis Eng, MD, PhD, FACP: Leading the Way in Genomic Medicine MD News - Nov 6, 2011 Dr. Charis Eng knew that she wanted to spend her working life in two places – the research bench and the patient bedside – even before the term ... Oncology Group's Report Calls for Smaller, More-Tailored Clinical Trials Plain Dealer - Nov 5, 2011 In May, less than a week after his dire diagnosis, the 39-year-old Hubbard man met with Dr. Neal Meropol, chief of the division of hematology and oncology ... Axitinib Looks Good in Head-to-Head Renal Cancer Trial MedPage Today - Nov 4, 2011 ... patients getting axitinib had a median progression-free survival of 6.7 months, according to Brian Rini, MD, of the Cleveland Clinic, and colleagues. ... Coulter Foundation, CWRU Establish $20M Endowment for Biomedical Engineering Projects Case Daily - Nov 2, 2011 "The Coulter Process more closely resembles a business model," said Jeffrey L. Duerk, PhD, chairman of biomedical engineering at Case Western Reserve. MARK YOUR CALENDARS Cancer Center Seminar Series: Network Medicine: Can a network approach to cancer enable new targeting strategies, drug targets and biomarkers? Friday, November 11 12-1 pm Frohring Auditorium - BRB 105 Please join us Friday, November 11 at the next Cancer Center Seminar Series featuring Eric B. Haura, MD, Associate Professor of Medicine and Oncology at H. Lee Moffitt Cancer Center and Research Institute. Dr. Haura will present Network Medicine: Can a network approach to cancer enable new targeting strategies, drug targets and biomarkers?, during which he will describe the work his lab is doing using mass spectrometry-based proteomics to characterize cancer kinase signaling networks and the relationships with drugs. He will also describe ongoing efforts to develop protein-protein interaction biomarker strategies. This seminar is hosted by the Developmental Therapeutics Program, but all are encouraged to attend. CME credit is available. FUNDING OPPORTUNITIES Robert Wood Johnson Foundation Community Health Leaders Each year, the Robert Wood Johnson Foundation Community Health Leaders program honors up to 10 outstanding and otherwise unrecognized individuals who overcome daunting odds to improve health and health care, especially to underserved populations in communities across the United States. The program aims to elevate the work of these unsung leaders through heightened recognition, technical assistance and new leadership opportunities. Deadline: November 28 ANNOUNCEMENTS ASCO Report Stresses Need for More Targeted Approach to Clinical Trials Dr. Neal Meropol was one of three executive editors of a newly released report by ASCO. Accelerating Progress Against Cancer, provides a high-level blueprint for transforming the translational and clinical cancer research system in the US. The report identifies and lays out plans to address three areas that are of immediate importance: Establishing a new approach to therapeutic development, driven by our more thorough understanding of cancer biology Designing smarter, faster clinical trials that are appropriate for the era of molecularly-targeted therapies Harnessing information technology to seamlessly integrate clinical and translational research and patient care, ensuring that every patient's experience can inform research and improve care Over the next three years, ASCO will work with partners throughout the cancer research community to develop more detailed plans of action for each of the three areas covered in the report. Gifts to CWRU SOM Establish Professorship in Integrative Oncology Today, the CWRU SOM announced gifts to establish the inaugural Parker Hannifin-Helen Moss Cancer Research Foundation Professorship in Integrative Oncology. The professorship seeks to change the way cancer is treated by employing the practice of integrative medicine and therapies designed to extend the lives of cancer patients using a more holistic and natural approach, along with traditional medicine. The Parker Foundation partnered with the Helen Moss Cancer Research Foundation by donating $1 million to help establish the $1.5 million professorship. Helen Moss, a stage-four breast cancer survivor and founder of the Helen Moss Cancer Research Foundation, has spent the past 10 years advocating for integrative oncology. She is the driving force behind the establishment of this professorship, and her foundation is a sponsor of the upcoming Society for Integrative Oncology Conference in Cleveland. NCI CANCER BULLETIN November 1, 2011 News Featured Article: Organ Transplant Recipients Are at Increased Risk for a Range of Cancers Annual Screening with Chest X-Ray Does Not Reduce Lung Cancer Deaths Radiation Therapy after Breast-Conserving Surgery Improves Survival Targeted Therapy Shows Benefit in Rare Type of Thyroid Cancer Study Confirms Letrozole Prevents More Breast Cancer Recurrences than Tamoxifen Study Suggests Smaller Melanoma Excision Margins May Be Option for Some Patients HPV Vaccine Reduces Anal HPV Infection and Precancerous Lesions In Depth Study Shows Aspirin Reduces Colorectal Cancer in Those at High Risk Tackling the Conundrum of Cachexia in Cancer Featured Clinical Trial: Cetuximab and Radiotherapy for HPV-Associated Oropharynx Cancer Updates CDC Update Cancer.gov Update Notes NEWS FROM NIH NIH Researchers Design a Light Therapy That Targets and Destroys Cancer Cells in Mice Researchers have designed a light-based therapy that allows the selective destruction of tumor cells in mice without harming surrounding normal tissue.	EVENTS All events are open to anyone interested in attending November 7 Pathology Graduate Student Seminar Chao Fang Schmaier Lab, Div. of Hem/Onc CWRU/UH Topic:** Elevated NO Decreases Arterial Thrombosis Risk in B2R KO Mice by Reducing GPVI Activation 12 pm WRB 1-413 SDIG Meeting Yunlong Liu, PhD Adjunct Assistant Professor, Informatics Assistant Professor, Medical & Molecular Genetics Adjunct Assistant Professor, Medicine (Biostatistics) Indiana University Topic: Decipher Non-coding RNA Mediated Regulatory Network, an Application of Next Generation Sequencing Technology 2:30 pm WRB 1-402 November 8 Pathology Graduate Student Seminar Mausita Karmakar Pearlman Lab CWRU Topic: Neutrophil Mediated IL-1β Processing During P. aeruginosa Keratitis AND Andrew Lavik Distelhorst Lab Topic: The Role of IP3 Receptor-Interacting Proteins in Regulating IP3 Receptor-Dependent Calcium Signals and Cell Survival 12 pm WRB 1-413 November 9 Hematology and Oncology Division Research Conference Ken Cooke, MD Director, Pediatric BMT Program Associate Professor, Pediatric Hematology/Oncology CWRU/UH Topic: Novel Approaches to Regulate GVHD 8 am Lerner B-151 Immunology Visiting Professor Seminar Series Leo Lefrançois, PhD Professor and Chairman, Immunology University of Connecticut Topic: It Takes Guts: Two Faces of Mucosal Memory T Cells 12 pm NC1-202 Cleveland Clinic November 10 November 11 Hematology/Oncology Fellows Conference Topic: TBD 8 am Wearn 137 Taussig Cancer Institute Grand Rounds Richard Maziarz, MD Medical Director, Adult Stem Cell Transplantation Program & Center for Hematologic Malignancies Oregon Health and Science University Topic: Can Adherent Stromal Cells Provide Efficacious Adjunctive Therapy in Hematopoietic Stem Cell Transplantation 8 am R3/002-003 Cleveland Clinic Cancer Center Seminar Series Eric B. Haura, MD Associate Professor, Medicine and Oncology H. Lee Moffitt Cancer Center and Research Institute Topic: Network Medicine: Can a network approach to cancer enable new targeting strategies, drug targets and biomarkers? 12 pm BRB 105 Cancer Center Research in Progress Seminar Tony Scott Graduate Student, Wang Lab CWRU/UH Topic: Regulation of Paxillin Tyrosine-88 Phosphorylation in Colorectal Cancer Development 4 pm WRB 3-136 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS ADDITIONAL UPCOMING SEMINARS & EVENTS 8th International Conference of the Society for Integrative Oncology: Innovating Integrative Oncology: New Science, New Solutions November 10-12 InterContinental Hotel Cleveland Details



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
Robert Wood Johnson Foundation Health Policy Fellows program Deadline: November 9 NCI Provocative Questions Project Deadline: November 14 Rita Allen Foundation Scholars Program Internal Deadline: November 14 AACR–Conquer Cancer Foundation of ASCO Young Investigator Translational Cancer Research Award Deadline: November 15 Cellular Molecular Imaging of Cancer Pilot Funding: Cancer Microenvironment Deadline Extended: November 17 SU2C-PCF Prostate Dream Team Translational Cancer Research Grant LOI Deadline: November 28 Burroughs Wellcome Fund Collaborative Research Travel Grants Deadline: December 1 CTSC Core Utilization pilot program Deadline: December 1 Kimmel Scholar Award Deadline: December 1 Kimmel Translational Science Award Deadline: December 1 American Medical Association Seed Grant Research Program Deadline: December 5 2012 NIH Director's Transformative Research Awards LOI Deadline: December 12 Application Deadline: January 12, 2012 L'Oréal USA Fellowships For Women In Science Deadline: December 15 Lymphatic Research Foundation (LRF) Postdoctoral Fellowship Program Deadline: January 10, 2012	HHMI Medical Research Fellows Program Deadline: January 11, 2012 2012 CTSC Annual Pilot Grant Funding Mandatory LOI Deadline: January 15 Oncology Nursing Society Foundation Connie Henke Yarbro Excellence in Cancer Nursing Mentorship Award Deadline: January 15, 2012 Robert Wood Johnson Foundation Executive Nurse Fellows Deadline: January 18, 2012 Innovations for Health: Solutions that Cross Borders Deadline: February 13, 2012 Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC) Deadline: Open AACR Scholar-in-Training Awards - Other Conferences and Meetings Deadline: Open Case CCC Protocol Specific Research Support (PSRS) Deadline: Open International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program Application Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities Academic Research Enhancement Award (Parent R15) (PA-12-006)
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216-844-8317 phone 216-844-7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.