 MESSAGE FROM THE DIRECTOR
Stan Gerson, MD
Director, Case CCC
Case Comprehensive Cancer Center and Case Western Reserve University Receive $5.4 Million Grant to Study Esophageal Cancer
Last week, the Case CCC announced the receipt of funding from the NCI to support the Barrett's Esophagus Translational Research Network (BETRNet). Researchers from multiple centers will collaborate to develop an understanding of the basis of Barrett's esophagus and its conversion to esophageal carcinoma. This is very exciting news for our Center, and speaks to the world-class group of researchers assembled by PI Dr. Amitabh Chak. This grant is the result of teamwork by researchers at the Case CCC, Johns Hopkins University, University of North Carolina at Chapel Hill, University of Pennsylvania, University of Washington/Fred Hutchinson Cancer Research Center, and Washington University in Saint Louis. Congratulations to everyone involved!
CASE CCC IN THE NEWS
New Targets for Treating Inflammatory, Autoimmune Diseases Discovered
Science Daily - Oct 8, 2011
Discovery of this pathway was the work of an active collaboration between Xiaoxia Li, Ph.D., and Thomas Hamilton, Ph.D., Department Chair, ...
Insurers Review Whether to Still Pay for Routine Screening
New York Times - Oct 7, 2011
Dr. Eric Klein, head of urology at the Cleveland Clinic, said he remained a believer in PSA tests and would still encourage men without symptoms of prostate ...
Icing Bone Cancer
WKYC-TV - Oct 7, 2011
Dr. David Prologo inserts a probe into the bone using CAT and MRI scans to guide him to the exact spot of the cancer lesion. Then the probe freezes the ...
Video: Latest Technology in Diagnosing and Treating Prostate Cancer
WCSH Portland - Oct 7, 2011
Dr. Lee Ponsky from University Hospitals Case Medical Center talks about the latest innovations in diagnosing, treating and managing prostate cancer
New Research Shows PET Imaging Effective in Predicting Lung Cancer Outcomes
HealthCanal.com - Oct 7, 2011
Mitch Machtay, MD, of the Seidman Cancer Center at University Hospitals (UH) Case Medical Center and principle investigator for the study, presented the ...
'Lost Boys' Have Found a New Home in Cleveland, but Haven't Forgotten Those Left Behind
Plain Dealer (blog) - Oct 5, 2011
Dr. Lee Ponsky started MedWish International, a Cleveland-based nonprofit, about 20 years ago when he was just 20 and wanted to change the world. ...
MARK YOUR CALENDARS
Cancer Center Seminar Series: Modeling the Genesis and Progression of Human Melanoma in the Mouse
Friday, October 14
12-1 pm
Frohring Auditorium - BRB 105
Please join us Friday, October 14 at the next Cancer Center Seminar Series featuring Glenn Merlino, PhD. Dr. Merlino, Chief of the Laboratory of Cancer Biology & Genetics and Deputy Director of the Center for Cancer Research at NCI, will present Modeling the Genesis and Progression of Human Melanoma in the Mouse.
Maximizing Resources to Effectively Recruit Participants for Research
Join the CWRU Office of Research Compliance Friday, October 28 from 8:30 am - 12 pm in the Wolstein Research Building Auditorium for a morning filled with the most current information available to enhance your research recruiting agenda. Experts will be on hand to provide practical guidance and share personal experiences. Sana Loue, JD, PhD, MPH, Associate Professor from CWRU's Bioethics and Epidemiology and Biostatistics Departments, will first discuss general recruitment strategies and methods. Next, Montana Miller, PhD, Assistant Professor of Popular Culture at Bowling Green State University, will outline the potential uses of social media strategies, including Facebook and Twitter, to enhance recruitment. Following the presentations, an expert panel of local researchers will be sharing their successes with various recruitment approaches. Pre-registration for this 6 CREC seminar is required.
Graft vs. Host Disease Conference
The Case CCC and the Meredith A. Cowden Foundation are bringing a national educational conference on Graft vs. Host Disease (GvHD) to Cleveland on Friday, November 4, 7:30 am to 5 pm, at the Renaissance Cleveland Hotel. The conference will unite leading specialists in hematology, oncology, bone marrow transplantation and immunology from more than a dozen of the nation's top cancer research centers and educational institutions to present information on cutting-edge research and treatments. Registration (includes CME credits), is $100 for physicians and pharmacists, $75 for nurses and other healthcare professionals and $25 for students. Please make every effort to register and attend.
FUNDING OPPORTUNITIES
AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research
The AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research provides funding to allow a meritorious young investigator to pursue an independent line of investigation within the context of his/her current fellowship placement. This grant provides a "bridge" between a training and an independent position, offering an opportunity for a young investigator to develop a new direction for his/her research program that otherwise may not have been possible in the absence of this funding.
Deadline: October 31
Urban Health Initiative (UHI) Pilot Grant
Pilot funds are available from CWRU SOM to address urban health issues through university-community partnerships. Proposals should use research to improve health conditions that exist or are exacerbated by living in a local distressed area and/or increase the preparedness of providers to address urban health issues. Applications are encouraged from SOM students and faculty as well as faculty from across campus; however, the PI must be a CWRU faculty member.
Deadline: November 1
Cellular Molecular Imaging of Cancer Pilot Funding: Cancer Microenvironment
The Case CCC is providing seed funding to develop a strong set of integrative cancer biology–molecular imaging projects that enhance interactions between clinical and basic science researchers with members of the Cancer Imaging Program. This funding will support investigative interdisciplinary teams with broad expertise in cancer biology, imaging science, pharmacology, or genetics with opportunities to explore aspects of cancer biology with non-invasive imaging technologies. Open to all Case, CCF and affiliate faculty members with a cancer or molecular imaging research track record.
See the RFA for more information.
Deadline: November 7
Rita Allen Foundation Scholars Program
CWRU has been invited to nominate ONE candidate for the Rita Allen Foundation Scholars Program, which supports research scientists in the early stages of their careers in the fields of research in analgesics, cancer, immunology and neurosciences. Candidates must have completed their training and provided persuasive evidence of distinguished achievement or extraordinary promise in research in of the relevant fields.
Internal Deadline: November 14
ANNOUNCEMENTS
Brady-Kalnay Receives Special Achievement Award
Dr. Susann Brady-Kalnay recently received the University of Dayton Alumni Special Achievement Award. Dr. Brady-Kalnay was recognized for her ground-breaking cancer research. Most recently, her research was featured on the cover of the September 1 issue of Cancer Research.
Jackson Publication Highlighted as "Top Story"
A publication by Dr. Mark Jackson and his research team was featured as the "Top Story" in the Mammary Cell e-news alert. The article, "c-MYC Functions as a Molecular Switch to Alter the Response of Human Mammary Epithelial Cells to Oncostatin M", was published October 5 online first in Cancer Research.
Keri Study Selected by F1000
A study conducted by Dr. Ruth Keri and Kristin Lozada, "Bisphenol A Increases Mammary Cancer Risk in Two Distinct Mouse Models of Breast Cancer" (Biol Reprod 2011 Sep 85 3:490-7), was highlighted by the peer-review service F1000, which places their work in a library of the top 2% of published articles in biology and medicine.
Importance of the OnCore Clinical Trials Management System Information for Cancer Center Support Grant Renewal
As we commence the Cancer Center Support Grant renewal period, it is critical that investigators and study staff ensure that research study information, including accrual data, is being entered into the OnCore database on an on-going basis. Accurate and timely information in OnCore forms a basis for our reporting capabilities for grant renewal purposes. Please make every effort to ensure that information on your studies in OnCore is complete.
Please contact April Firstencel 216-286-2294 or april.firstencel@uhhospitals.org with any questions regarding OnCore access, training and data entry.
NCI CANCER BULLETIN
October 4, 2011
News
Featured Article: Combination Therapy May Help Some Patients with Advanced Breast Cancer
Rising Oropharyngeal Cancer Rates Linked to HPV Infection
Hospitalization Following Prostate Biopsy Common in Older Men
Study Examines Sex Differences in Screening Colonoscopy Findings
Delivering Chemotherapy to the Liver May Benefit Patients with Metastatic Melanoma
Smoking Cessation Drug Proves Effective in Single-Center Trial
Also in the Journals: Zoledronic Acid May Benefit Postmenopausal Women with Breast Cancer
Commentary
NCI's Office of Advocacy Relations: Bringing Advocacy and Research Together
A Conversation with Dr. Jane Perlmutter about the Role of Advocates in Cancer Research
In Depth
Workshop Examines Causes, Potential Remedies for Drug Shortages
Changing Face of Cancer in HIV-Positive Patients Requires New Approaches to Clinical Trials
Featured Clinical Trial: Testing Adjuvant Ipilimumab in Advanced Melanoma
NCI Director's Consumer Liaison Group Focuses on Improving Clinical Trials
Updates
FDA Update
NIH Update
Legislative Update
Cancer.gov Update
Notes
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EVENTS
**All events are open to anyone interested in attending
October 10
Pathology Research Seminar Series: Harvey Werber Memorial Lecture
Betty Diamond, MD
Adjunct Professor, Microbiology & Immunology
Yeshiva University
Topic: Antibodies and the Brain: Lessons from Lupus
12 pm WRB 1-413
SDIG Meeting
Matthew Ruffalo
PhD Student, EECS
CWRU
Topic: Split Alignment for Accurate Structural Variation Detection
2:30 pm WRB 1-402
Physiology and Biophysics Seminar
Mitchell Chesler, MD, PhD
Professor, Neurosurgery and Physiology and Neuroscience
Vice Chair of Research, Neurosurgery
New York University
Topic: Regulation and Modulation of Extracellular pH and Its Impact on Excitatory Synaptic Transmission
4 pm SOM E501
Skeletal Research Center
J. Michael Sorrell, PhD
Senior Research Associate, Skeletal Research Center, Biology
CWRU/UH
Topic: How to Make Fat in Culture
4 pm Millis 123
October 11
Cancer Biology Mid-Term Review Seminar
Haifeng Yang, PhD
Assistant Staff, Cancer Biology
Cleveland Clinic
Topic: Von Hippel- Lindau, Histone Modification and Kidney Cancer
10 am NC1-202 Cleveland Clinic
Immunology Seminar Series
John Harty, PhD
Endowed Chair in Microbial Immunology
Professor, Microbiology
University of Iowa
Topic: T Cell Responses and Immunity to Blood-Stage Malaria
12 pm WRB 1-413
October 12
Hematology and Oncology Division Research Conference
Paula Silverman, MD
Associate Professor, Medicine-Hem/Onc
CWRU/UH
AND
Peter Oppelt, MD
Resident, Medicine
CWRU/UH
Topic: Patient Satisfaction on Inpatient Hematology and Oncology Services
8 am Lerner B-151
Immunology Visiting Professor Seminar Series
John Harty, PhD
Endowed Chair in Microbial Immunology
Professor, Microbiology
University of Iowa
Topic: What Are You Doing in My T Cell Memories?
12 pm NC1-202
Frontiers in Biological Sciences Lecture Series
Wei Gu, PhD
Professor, Pathology and Cell Biology
Columbia University
Topic: What Do We Really Know About p53?
4 pm SOM E301
October 13
October 14
Cancer Center Research in Progress Seminar canceled
Hematology/Oncology Fellows Conference
Nathan Langer, MD
Fellow, Div. of Hem/Onc
CWRU/UH
Topic: Oncology
8 am Wearn 137
Taussig Cancer Institute Grand Rounds
Stephanie Lee, MD
Fred Hutchinson Cancer Center
Topic: Chronic Graft-vs-Host Disease: Six Years After the NIH Consensus
8 am R3/002-003 Cleveland Clinic
Cancer Center Seminar Series
Glenn Merlino, PhD
Chief, Laboratory of Cancer Biology & Genetics
Deputy Director, Center for Cancer Research
National Cancer Institute, National Institutes of Health
Topic: Modeling the Genesis and Progression of Human Melanoma in the Mouse
12 pm BRB 105
Dental Medicine Seminar
Aaron Weinberg, DMD, PhD
Associate Professor and Chair, Biological Sciences
Associate Dean for Research, School of Dental Medicine
CWRU/UH
Topic: New Developments in Oral Cancer: When Too Much of a Good Thing is Bad!
2:30 pm WRB 5-136
Case CCC Calendar
LRI Calendar
UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS
Graft Versus Host Disease Conference
November 4
Renaissance Cleveland Hotel, 24 Public Square, Cleveland
Details
Registration
ADDITIONAL UPCOMING SEMINARS & EVENTS
8th International Conference of the Society for Integrative Oncology: Innovating Integrative Oncology: New Science, New Solutions
November 10-12
InterContinental Hotel Cleveland
Details
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