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Case Comprehensive Cancer Center Newsletter

August 1, 2011

CASE CCC IN THE NEWS

Cleveland Clinic Doctors Link Esophageal Cancer to Genes
CBS News - Jul 28, 2011
"We are absolutely thrilled to now know three distinct genes that link to BE/EAC," study leader Dr. Charis Eng, director of the clinic's Genomic Medicine ...

Your Medical Family Tree
Salt Lake Tribune - Jul 27, 2011
"Most alarmingly, the genome screening missed all of the people at high risk for colon cancer," says Charis Eng, MD, Ph.D., chair of the clinic's Genome Medicine Institute. So take the time to bring your medical history up to date. ...


ANNOUNCEMENTS

Dr. Brian Bolwell Named Chairman of Taussig Cancer Institute
bolwell

Congratulations to Dr. Brian Bolwell, who was recently appointed as Chairman of the Taussig Cancer Institute. Dr. Bowell is currently Professor of Hematology & Medical Oncology, and has served as interim chair since late last year when Dr. Derek Raghavan resigned. Please join us in congratulating Dr. Bolwell in his new role!

Case CCC Clinical Trials Standard Operating Procedures (SOPs)

The Case CCC has posted clinical trials Standard Operating Procedures (SOPs) on the Clinical Research Portal website. SOPs apply to those members of the clinical research teams who are involved in conducting cancer research and clinical trials at the Case CCC. The Cancer Center implements and enforces all SOPs across consortium institutions: Case Western Reserve University, Cleveland Clinic and University Hospitals. Questions about the SOPs should be directed to Katarzyna Karelus, Administrative Director, Clinical Research Office, 216-368-6287 or katarzyna.karelus@case.edu.

Clinical Research Scholar Career Development Training Opportunity

The CTSC KL2 seeks outstanding candidates to fill Clinical Research (CR) Scholar positions available in July 2012. The training program is funded by the NIH and it is a component of the Cleveland Clinical and Translational Science Collaborative. This innovative program is a collaboration involving CWRU, Cleveland Clinic, UH and MetroHealth. Each CR Scholar will embark on a 4-year program of intensive training in interdisciplinary team-based, patient-oriented research, combining a novel educational program with mentored research experiences.

Interested applicants are encouraged to attend upcoming informational sessions. To make a reservation, please contact contact Beth Spyke, MPA at spykeb@ccf.org or 216-444-2702. Applications will be accepted through October 10.


MARK YOUR CALENDARS

Minority Recruitment and Cancer Research Retreat

Mark your calendars for the Minority Recruitment and Cancer Research Retreat, August 30 from 3-6 pm in the Wolstein Research Building Auditorium. Please join us as we explore in a retreat setting (plenary and break-out sessions) issues related to minority recruitment to cancer clinical trials. Registration will be required due to a limited space. Stay tuned!

Imaging Solutions In Cancer Management: A Case-Based Conference

Registration is now open for Imaging Solutions In Cancer Management: A Case-Based Conference. Join us September 8 for this comprehensive oncologic imaging course, which focuses on cancer management using imaging as a diagnostic tool and as a guide for minimally invasive therapeutic applications. This course takes a practical approach using cases and features multiple specialists ranging from medical oncologists, radiation oncologists, surgeons, radiologists and basic scientists.

This conference will be simultaneously broadcast on line. See the brochure for details.


NCI CANCER BULLETIN

July 26, 2011- Special Issue: Adolescent and Young Adult Cancers

Commentary
Guest Commentary: Toward a New Understanding of Cancers in Adolescents and Young Adults

Cancer Research Now: Adolescent and Young Adult Cancers

Features
Uncovering the Biology of Cancers in Adolescents and Young Adults

Clinical Trials Offer a Path to Better Care for AYAs with Cancer

For Many Young Cancer Survivors, Late Effects Pose Lasting Problems

AYAs Are Not Alone: Confronting Psychosocial Challenges of Cancer

A Conversation with Matthew Zachary: The Young Adult Cancer Movement

Highlights
Breast Cancer Cells Found by Immunochemistry in Sentinel Nodes Not Associated with Survival

Radiation Plus Short-Term Hormone Therapy Improves Survival of Men with Early-Stage Prostate Cancer

In Hodgkin Lymphoma Study, Side Effects Distinguish Treatments

Updates
FDA Update

Notes

EVENTS

calendar

**All events are open to anyone interested in attending

August 1

Cancer Imaging Program Special Presentation
Buck Rogers, PhD
Associate Professor, Radiation Oncology- Radiation and Cancer Biology
Washington University
Topic: Development of Targeted Radiopharmaceuticals for Cancer Imaging and Therapy
12 pm Wearn B37


August 2

School of Dental Medicine Seminar
Praveen Arany, PhD
Harvard University
Topic: Low Power Laser-Generated ROS Activates Latent TGF-beta1 that Directs Dental Stem Cell Differentiation
12 pm Rottman Seminar Room W203


August 3

Hematology and Oncology Research Conference
Panos Savvides, MD
Assistant Professor, Medicine-Hem/Onc
CWRU/UH
Topic: Introduction to Head and Neck Cancer
8 am Lerner B-151


August 4

Stem Cell Biology and Regenerative Medicine Seminar
Kamalakannan Palanichamy, PhD
Assistant Professor, Radiation Medicine
Ohio State University
Topic: Exploring the MicroRNA Genome of Radioresistant GSCs to Identify Targets of Therapeutic Intervention
1 pm NE1-205 Cleveland Clinic

Olof Pearson Lecture
Dennis A. Carson, MD
Director Emeritus
Moores UCSD Cancer Center
Topic: Treatment of Hairy Cell Leukemia: from Bench to Bedside
4 pm Wolstein 1-413


August 5

Cancer Center Research in Progress Seminar will resume September 2.

Hematology/Oncology Fellows Curriculum Series
Afshin Dowlati, MD
Associate Professor, Medicine-Hem/Onc
CWRU/UH
Topic: Introduction to Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer
8 am Wearn 137

Hematology/Oncology Fellows Curriculum Series
Howard Meyerson, MD
Associate Professor, Clinical Pathology
CWRU/UH
Topic: Introduction to Morphology- Bone Marrow Biopsy
1-2 pm Pathology B-22

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Imaging Solutions in Cancer Management: A Case-based Conference
September 8
Registration

ADDITIONAL UPCOMING SEMINARS & EVENTS

MSC 2011: Innovations in Cell-Based Regenerative Therapies
August 22-24
Cleveland Marriott Downtown at Key Center
Details

First Ascoli Piceno Conference on Gene Vaccination in Cancer
September 15-17
Ascoli Piceno, Italy
Details

8th International Conference of the Society for Integrative Oncology: Innovating Integrative Oncology: New Science, New Solutions
November 10-12
InterContinental Hotel Cleveland
Details


FUNDING OPPORTUNITIES

Multiple Myeloma Research Foundation (MMRF) Biotech Investment Award

The Multiple Myeloma Research Foundation (MMRF) seeks proposals for its Biotech Investment Award program (BIA). The goal of this initiative is to drive and accelerate the development of innovative and effective treatments for myeloma. By funding the early stages of drug discovery and development, BIA will have significant impact on future myeloma treatments.

LOI Deadline: August 23
Full Proposal Deadline: November 1

St. Baldrick's Foundation Infrastructure Grants

St. Baldrick's Foundation has released a call for applications for Infrastructure Grants. These grants are intended for institutions with the potential to participate significantly more in childhood cancer clinical trials, but which are smaller or have barriers to greater participation due to a lack of resources. Preference will be given to institutions that serve populations which might have limited access to participation in clinical trials without access to appropriately resourced institutions.

Deadline: September 6

Hope Funds for Cancer Research Postdoctoral Fellowship

The Hope Funds for Cancer Research is offering fellowships to postdoctoral scientists who propose to work on highly innovative research projects that challenge the traditional paradigms of understanding the causes, mechanisms, progression, disease markers or risk factors of the most difficult-to-treat cancers, including pancreatic, lung, liver, sarcomas, esophageal, brain, gastric, bone and ovarian cancers; and rare leukemias, lymphomas and MDS. The Trustees of the Hope Funds believe that funding research that could lead to breakthroughs in these areas and increase life expectancy in these types of cancers is at the core of its mission. The Fellowship Review Committee will consider each of the following criteria, with a strong emphasis on the innovation of the project, in evaluating candidates.

Proposal Deadline: September 16

FY11 Breast Cancer Research Program (BCRP)

The Breast Cancer Research Program (BCRP) has released two more funding opportunities:

The BCRP Clinical Translational Research (CTR) Award is intended to promote significant improvements over current approaches to breast cancer prevention and therapy, such as studies that would better align treatment options with more specific breast cancer subtypes, vaccine studies that will prevent primary or recurrent breast cancer, and studies that may result in a new treatment to prevent breast cancer progression to metastasis. The CTR Award supports research projects that are likely to have a major impact on breast cancer by applying promising research findings to patients with, or populations at risk for, breast cancer.

Pre-Application Deadline: September 20
Application Deadline: December 22

The BCRP Impact Award supports unique research projects or ideas (from small- to large-scale) that specifically focus on scientific and clinical breast cancer issues, which, if successfully addressed, could ultimately revolutionize the understanding, prevention, and/or treatment of breast cancer and make major advances towards the goal of eradicating the disease. The BCRP particularly encourages applications that focus on poorly understood issues that are of critical significance in breast cancer, such as those related to susceptibility, recurrence, or metastasis. The proposed work must be based on sound overall research and fully supported by preliminary data and/or published reports.

Pre-Application Deadline: September 20
Application Deadline: December 22

DeGregorio Family Foundation for Stomach and Esophageal Cancer Research and Education

The DeGregorio Family Foundation for Gastric and Esophageal Cancer is pleased to announce a funding opportunity for gastroesophageal malignancies. The Foundation seeks to promote and facilitate collaborative research on the pathogenesis, early diagnosis, and treatment of upper gastrointestinal malignancies. We wish to support high quality and innovative bench, clinical, and translational research to improve our understanding of the biology of these diseases, identification of potential novel therapeutic targets, or in the development and evaluation of novel biomarkers for early diagnosis and treatment.

Deadline: November 1

Case CCC Clinical Trials Funding Opportunity

The Case Comprehensive Cancer Center is announcing the availability of Protocol Specific Research Support (PSRS) funding for Year 2011. The budgeted funds are for the conduct of early phase clinical trial and restricted to support research nurses and data managers directly involved in the conduct of these clinical trials. Studies developed jointly between UH and CCF with planned accrual at both institutions will be prioritized. Please direct questions and requests for information about the funding process to Katarzyna Karelus, Administrative Director, Case Comprehensive Cancer Center Clinical Research Office, at (216) 368-6287 or katarzyna.karelus@case.edu.


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

CTSC Core Utilization Pilot Grants
Deadline: August 1

International Myeloma Foundation Brian D. Novis Research Grant program
Deadline: August 1

Prostate Cancer Foundation Young Investigator Awards 2011
Deadline: August 1

Susan G. Komen for the Cure Promise Grants
Pre-Application Deadline: August 1
Full Application Deadline: December 15

DOD LCRP Early Investigator Synergistic Idea Award
Pre-Application (Preproposal) Deadline: August 3
Application Deadline: November 9

DOD LCRP Investigator Initiated Translational Research Award
Pre-Application (Preproposal) Deadline: August 3
Application Deadline: November 9

DOD LCRP Promising Clinician Research Award
Pre-Application (Preproposal) Deadline: August 3
Application Deadline: November 9

Mesothelioma Applied Research Foundation
Deadline: August 5

PRCRP Visionary Postdoctoral Fellowship Award
Pre-application Deadline: August 10
Application Deadline: November 22

Susan G. Komen for the Cure Investigator-Initiated Research (IIR) Grants
Pre-Application Deadline: August 10
Full Application Deadline: December 15

Vilcek Prize for Creative Promise in Biomedical Science
Deadline: August 14

Damon Runyon Fellowship Award
Application Deadline: August 15

Uniting Against Lung Cancer 2011 Legacy Program for Advances in Lung Cancer Research
Deadline: August 17

Avon Breast Health Outreach Program (BHOP)
Deadline: August 26

Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research
Pre-Application Deadline: August 30
Full Application Deadline: November 15

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Pre-Application Deadline: August 30
Full Application Deadline: January 5

Induced Pluripotent Stem Cell Pilot Research Award
Deadline: August 31

SWOG Biorepository of Specimens Research Proposals
Proposal Deadline: September 1

AACR Team Science Award
Deadline: September 6

Concern Foundation CONquer canCER Now Award
LOI Deadline: September 8
Application Deadline: December 8

National Lung Cancer Partnership Young Investigator Research Grants
Deadline: September 9

Lustgarten Foundation Innovator Awards Program- Basic Research
Concept Deadline: September 12
Full Proposal Deadline: October 31

Pezcoller Foundation-AACR International Award for Cancer Research
Deadline: September 12

Lustgarten Foundation Fall 2011: Basic Research Innovator Awards
Concept Proposal Deadline: September 14
Full Application Deadline: October 31

Leukemia & Lymphoma Society (LLS) Scholar
Letter of Intent Deadline: September 15
Application Deadline: October 1

Leukemia & Lymphoma Society (LLS) Scholar in Clinical Research
Letter of Intent Deadline: September 15
Application Deadline: October 1

Leukemia & Lymphoma Society (LLS) Special Fellow
Letter of Intent Deadline: September 15
Application Deadline: October 1

Leukemia & Lymphoma Society (LLS) Special Fellow in Clinical Research (SFCR)
Letter of Intent Deadline: September 15
Application Deadline: October 1

Leukemia & Lymphoma Society (LLS) Fellow
Letter of Intent Deadline: September 15
Application Deadline: October 1

DOD Defense University Research Instrumentation Program (DURIP)
Deadline: September 20

AACR-American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention
Deadline: September 26

AACR Award for Lifetime Achievement in Cancer Research
Deadline: September 26

Szent-Györgyi Prize for Progress in Cancer Research
Nomination Deadline: September 30

Burroughs Wellcome Fund Medical Scientist Career Awards
Deadline: October 1

AACR-Women in Cancer Research Charlotte Friend Memorial Lectureship
Deadline: October 11

AACR G.H.A. Clowes Memorial Award
Deadline: October 11

AACR-Minorities in Cancer Research Jane Cooke Wright Lectureship
Nomination Deadline: October 11

AACR Award for Outstanding Achievement in Cancer Research
Deadline: October 11

Robert Wood Johnson Foundation Scholars in Health Policy Research program
Deadline: October 12

Leukemia & Lymphoma Society Specialized Center of Research Program
Deadline: November 1

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation Collaborative Activity Awards
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Revised Instructions for Inclusion of Appendix Materials in Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (Parent T32) (NOT-OD-11-100)

Resubmission of Applications with Pending Appeals of NIH Initial Peer Review (NOT-OD-11-101)

Alliance of Glycobiologists for Detection of Cancer (U01) (RFA-CA-11-009)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.