Case Comprehensive Cancer Center: Weekly Newsletter

Home | Back to newsletter main page



May 23, 2011
CASE CCC IN THE NEWS Experts Discuss Emerging Treatments and Multi-Disciplinary Approaches to Prostate Cancer Care Sacramento Bee - May 20, 2011 "The development of stereotactic radiosurgery capabilities has opened up new possibilities for the non-invasive treatment of kidney and prostate cancer," said Lee E. Ponsky, MD, director of the Center for Urologic Oncology and Minimally Invasive ... Seidman Cancer Center to Offer Cutting Edge Technology Cleveland News - Fox 8 - May 17, 2011 "Proton technology is a remarkable type of new radiation technology that will impact the way we treat patients with radiation," said Dr. Nathan Levitan, president of the Seidman Cancer Center...."This is heavier particle that delivers all of its energy wherever we tell it to, and the computers simulate it to do so," said Dr. Stan Gerson, director of the Seidman Cancer Center. "And so much greater percentage of the energy goes directly into the ... University Hospitals Plans $30 Million Proton Therapy Center Plain Dealer - May 17, 2011 About half of all cancer patients receive radiation as part of their treatment, said Dr. Mitch Machtay, chairman of radiation oncology at UH Case Medical Center and Case Western Reserve University School of Medicine. Proton therapy isn't the automatic ... MARK YOUR CALENDARS Cancer Center Seminar Series: Personalized Medicine in Clinical Trials Friday, May 27 12-1 pm Frohring Auditorium - BRB 105 Please join us Friday, May 27 at the next Cancer Center Seminar Series featuring Donald A. Berry, PhD, Head of Division of Quantitative Sciences and Professor and Chair of Biostatistics- Quantitative Sciences at the University of Texas MD Anderson Cancer Center. Dr. Berry will present Personalized Medicine in Clinical Trials. Donald Berry is a research professor in the Department of Biostatistics of the University of Texas MD Anderson Cancer Center. He was founding Chair of this department in 1999. Since 1990, he has served as a faculty statistician on the Breast Cancer Committee of the Cancer and Leukemia Group B (CALGB), a national oncology group. In this role, he has designed and supervised the conduct of many large U.S. intergroup trials. Through Berry Consultants, LLC he has consulted with many pharmaceutical and medical device companies on clinical trial design and analysis issues. He is well known as a developer of Bayesian adaptive designs that minimize sample size while increasing the likelihood of detecting drug activity, efficiently using information that accrues over the course of the trial. Since 1999, the Department of Biostatistics has designed over 300 clinical trials that take a Bayesian approach. He is co-developer (with Giovanni Parmigiani) of BRCAPRO, a widely used program that provides individuals' probabilities of carrying mutations of breast/ovarian cancer susceptibility genes BRCA1 and BRCA2. Dr. Berry received his PhD in statistics from Yale University, and previously served on the faculty at the University of Minnesota and Duke University. He has held endowed positions at Duke University and MD Anderson. Dr. Berry is the author of several books on biostatistics and over 300 published articles, including first-authored articles in the New England Journal of Medicine, Journal of the American Medical Association, and Nature. Dr. Berry has been the principal investigator for numerous research grants from the National Institutes of Health and the National Science Foundation. He is a Fellow of the American Statistical Association and of the Institute of Mathematical Statistics. Case CCC Annual Scientific Retreat The Case CCC Annual Scientific Retreat will be July 8-9 at Corporate College East. Details will be posted soon. FUNDING OPPORTUNITIES Pilot Project Grants: American Cancer Society IRG Awards The Case CCC is currently accepting applications for American Cancer Society Institutional Research Grant (IRG) awards. Pilot funding is available for projects in basic, clinical, prevention and control, behavioral, health services, and epidemiology cancer research with awards up to $30,000 for one-year cancer research projects that provide the basis for future independent grants. Instructions, frequently asked questions, and application forms are available at http://cancer.case.edu. Contact Terri Daso, Cancer Center Administration (844-7252, tld6@case.edu) for more information. LOI Deadline: June 13 Application Deadline: July 5, 2011 AACR Research Grant Funding The AACR is accepting applications for the following opportunities: Breast Cancer Research Foundation-AACR Grants for Translational Breast Cancer Research These two-year Grants will provide up to $150,000 over the grant term ($75,000 per year) for innovative cancer research projects designed to accelerate the discovery, development, and application of new agents to treat breast cancer and/or for pre-clinical research with direct therapeutic intent. LOI Deadline: June 13 AACR-Aflac, Inc. Career Development Award for Pediatric Cancer Research This two-year grant of $100,000 ($50,000 per year) is open to junior faculty who are in the first 4-years of a faculty appointment (at the start of the grant term). The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pediatric cancer. Application Deadline: June 20 Case CCC Clinical Trials Funding Opportunity The Case Comprehensive Cancer Center is announcing the availability of Protocol Specific Research Support (PSRS) funding for Year 2011. The budgeted funds are for the conduct of early phase clinical trial and restricted to support research nurses and data managers directly involved in the conduct of these clinical trials. Studies developed jointly between UH and CCF with planned accrual at both institutions will be prioritized. Please direct questions and requests for information about the funding process to Katarzyna Karelus, Administrative Director, Case Comprehensive Cancer Center Clinical Research Office, at (216) 368-6287 or katarzyna.karelus@case.edu. ANNOUNCEMENTS PNAS Publication Cancer Center Members Drs. David Danielpour and Mark Jackson along with Rocky Cipriano, Charlene Kan, James Graham, and Martha Stampfer, co-authored the publication TGF-β signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells, which was published in the May 17 issue of "PNAS". This paper was edited by Dr. George Stark. ASCO Annual Meeting The Cancer Center is attempting to track members who are part of the formal program or presenting a poster at the ASCO Annual Meeting, June 3-7 in Chicago. Please send information to gillian.irwin@case.edu. NCI CANCER BULLETIN May 17, 2011 News Featured Article: Chemotherapy Regimen Extends Survival in Advanced Pancreatic Cancer Patients Study Finds Colonoscopy Screening Overused in Medicare Beneficiaries Prostate Cancer Study Provides More Data on Surgery versus Watchful Waiting Breast Cancers Arising between Mammograms Have Aggressive Features Patient Reports of Family Cancer History Are Often Inaccurate In Depth In Rare Skin Cancer, Virus Emerges as Target and Tool Straight from the Source: Electronic Patient-Reported Outcomes Combining Targeted Cancer Therapies: Much Promise, Many Hurdles Featured Clinical Trial: Lenalidomide and Radiation for Children with Brain Cancers Updates FDA Update Legislative Update Notes	EVENTS All events are open to anyone interested in attending May 23 May 24 Center for Global Health and Diseases Special Seminar Deborah Lehmann, MBBS, MSc Senior Researcher Telethon Institute for Child Health Research Topic:** Pneumococcal Vaccine Trials in Papua New Guinea 9:45 am WRB 4-136 Cancer Biology Invited Speaker Seminar Jan Van Deursen, PhD Professor, Pediatrics and Adolescent Medicine, and Biochemistry Mayo Clinic Topic: Mitotic Checkpoint Control in Cancer and Aging 11 am NC1-202 Cleveland Clinic Center for Global Health and Diseases Special Seminar Michael Alpers, MD Professor, International Health Curtin University of Technology of Western Australia Topic: Kuru: Clinical and Aetiological Aspects 11 am WRB 4-136 May 25 Hematology and Oncology Division Research Conference Lili Liu, PhD Associate Professor, Medicine-Hem/Onc CWRU/UH Topic: Impact of Uracil-DNA Glycosylase on Cytotoxicity of Pemetrexed: Identifying a Potential Target for New Drug Development Immunology Invited Speaker Seminar Series Christopher King, MD Professor, International Health, Medicine and Pathology Center for Global Health and Disease CWRU Topic: Natural Acquired Immunity to Malaria 12 pm NC1-202 Cleveland Clinic School of Dental Medicine Seminar Maura Gillison, MD, PhD Professor, Medicine, Epidemiology and Otolaryngology Chair of Cancer Research, Div. of Medical Oncology Ohio State University Topic: Oral HPV Infection and Disease in Immunocompetent and Immunosupressed Populations 12 pm SOM W203 Cancer Imaging Program (CIP) Meeting: Cancer Imaging at the Cleveland Clinic Steve Huang, MD, PhD Assistant Professor, Nuclear Medicine CWRU/ Cleveland Clinic Topic: Developing PSMA Targeting Tracers AND Gordon McLennan, MD Staff Physician, Diagnostic Radiology Cleveland Clinic Topic: Local Delivery of NAD Analogs for Treatment of Cancer AND Shyam Srinivas, MD, PhD Vice Chair, Nuclear Medicine Cleveland Clinic Topic: New Applications for PET Imaging in Cancer- It's Not Just FDG Anymore 2 pm Wearn B37 May 26 Stem Cell Biology and Regenerative Medicine Seminar Guoqiang Gu, PhD Associate Professor, Cell and Developmental Biology Vanderbilt Medical Center Topic: Ngn3 Directs Islet Cell Production by Regulating Both Positive and Negative Regulators 1 pm NE1-205 Cleveland Clinic May 27 Taussig Cancer Institute Grand Rounds canceled Hematology/Oncology Fellows canceled Cancer Center Seminar Series Donald A. Berry, PhD Head, Division of Quantitative Sciences Professor and Chair, Biostatistics- Quantitative Sciences University of Texas MD Anderson Cancer Center Topic: Personalized Medicine in Clinical Trials 12 pm BRB 105 Immunology Seminar Sulie Chang, PhD Professor, Biological Studies Director, Institute of NeuroImunne Pharmacology Seton Hall University Topic: Morphine Modulation of the Neuroimmune Circuit 12 pm NC1-202 Cleveland Clinic Cancer Center Research in Progress Seminar Snehal Dabir, MD, PhD Postdoctoral Scholar, Dowlati Lab, Div. of Hem/Onc CWRU/UH Topic: PIAS3- Potential Role in Mesothelioma and Interaction with p53 4 pm WRB 3-136 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS ASCO Review 2011 June 30 InterContinental Hotel and Bank of America Conference Center Details Case CCC Annual Scientific Retreat July 8-9 Details to follow ADDITIONAL UPCOMING SEMINARS & EVENTS Race for the Place June 5 Beachwood Place Mall Details International Society for Stem Cell Research (ISSCR) Annual Meeting June 15-18 Toronto, Canada Details Cancer Health Disparities Summit 2011 July 13-15 Bethesda North Marriott Hotel in Rockville, Maryland Details 8th International Conference of the Society for Integrative Oncology: Innovating Integrative Oncology: New Science, New Solutions November 10-12 InterContinental Hotel Cleveland Details

PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
Robert Wood Johnson Foundation Public Health Services and Systems Research Grant Proposal Deadline: May 24 STERIS Corporation Infectious Diseases Research Support Grant Application Deadline: May 27 Contact Martha Salata at mks18@case.edu for more information. DOD CDMRP Breast Cancer Research Program Idea Award Pre-Application Deadline: May 31 Application (Invited) Deadline: August 25 DOD CDMRP Breast Cancer Research Program Transformative Vision Award Pre-Application Deadline: May 31 Application (Invited) Deadline: August 25 Damon Runyon-Rachleff Innovation Award Pre-Proposals Deadline: June 1 Full Proposal Deadline: September 2 DOD CDMRP Prostate Cancer Research Program Idea Development Award Pre-Application Deadline: June 2 Application Deadline: August 23 DOD CDMRP Prostate Cancer Research Program Synergistic Idea Development Award Pre-Application Deadline: June 2 Application Deadline: August 23 DOD CDMRP Breast Cancer Research Program Postdoctoral Fellowship Award Pre-Application Deadline: June 7 Application Deadline: June 21 DOD CDMRP Breast Cancer Research Program Innovator Award Pre-Application Deadline: June 7 Application Deadline: June 21 DOD CDMRP Breast Cancer Research Program Era of Hope Scholar Award Pre-Application Deadline: June 7 Application Deadline: June 21 DOD CDMRP Ovarian Cancer Research Program Pilot Award Pre-Application Deadline: June 8 Application Deadline: August 18 DOD CDMRP Ovarian Cancer Research Program Translational Pilot Award Pre-Application Deadline: June 8 Application Deadline: August 18 DOD CDMRP Ovarian Cancer Research Program Translational Leverage Award Pre-Application Deadline: June 8 Application Deadline: August 18 DOD CDMRP Ovarian Cancer Research Program Teal Innovator Award Pre-Application Deadline: June 8 Application Deadline: August 18	DOD CDMRP Prostate Cancer Research Program Clinical Trial Award Pre-Application (Preproposal) Deadline: June 10 Application Deadline: September 1 Society of Surgical Oncology Clinical Investigator Award in Breast Cancer Research Deadline: July 8 DOD CDMRP Prostate Cancer Research Program Impact Award Pre-Application Deadline: June 10 Application Deadline: September 1 DOD CDMRP Prostate Cancer Research Program Laboratory - Clinical Transition Award (Modified) Pre-Application Deadline: June 10 Application Deadline: September 1 James S. McDonnell Foundation 21st Century Science Initiative 2011 Deadline: July 15 International Myeloma Foundation Brian D. Novis Research Grant program Deadline: August 1 Mesothelioma Applied Research Foundation Deadline: August 5 Damon Runyon Fellowship Award Application Deadline: August 15 Uniting Against Lung Cancer 2011 Legacy Program for Advances in Lung Cancer Research Deadline: August 17 Lustgarten Foundation Fall 2011: Basic Research Innovator Awards Concept Proposal Deadline: September 14 Full Application Deadline: October 31 Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC) Deadline: Open AACR Scholar-in-Training Awards - Other Conferences and Meetings Deadline: Open International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open James S. McDonnell Foundation Collaborative Activity Awards Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities Clarification of NIH Fiscal Policy for Grant Awards FY 2011 (NOT-OD-11-077) National Institutes of Health
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216-844-8317 phone 216-844-7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.