Case Comprehensive Cancer Center: Weekly Newsletter

Home | Back to newsletter main page



April 18, 2011
CASE CCC IN THE NEWS Leukemia Drug is Just One of Many Chemo Drugs in Short Supply Plain Dealer - Apr 18, 2011 University Hospitals' Dr. John Letterio said medical centers don't get advanced notice of manufacturing delays, but should. This is a critical issue, he said, because cancer patients get chemotherapy on specific schedules. A delay in treatment due to ... In the Works: Decoding Tumors in Search of More Effective Cancer Treatments Los Angeles Times - Apr 17, 2011 The approach is "skinny and deep," adds Dr. Charis Eng, director of the Genomic Medicine Institute at the Cleveland Clinic, "and that's a good thing." White is partnering with several doctors who can use his sequences to advance their research. ... MARK YOUR CALENDARS Case CCC Scientific Series: Immunology The next installment of the Case CCC Scientific Series is scheduled for Thursday, April 21 from 4-6:30 pm in Wolstein Auditorium (WRB 1-413). Drs. Anton Gorbachev, Neetu Gupta and Alex Huang will discuss the topic of Immunology: Anton Gorbachev, PhD: Down-Regulation of CXCL9/Mig Expression in the Tumor Microenvironment as a Result of Immunoediting Neetu Gupta, PhD: A Novel Signaling Link Between Ezrin and JNK Regulates Antigen-Dependent B Cell Survival Alex Huang, MD, PhD: Measuring Immune Surveillance in Tissue Microenvironment Presentations will be followed by a short reception. All are encouraged to attend. Cancer Center Seminar Series: Development of a Prophylactic Breast Cancer Vaccine Friday, April 22 12-1 pm Frohring Auditorium - BRB 105 Please join us Friday, April 22 at the next Cancer Center Seminar Series featuring Vincent K. Tuohy, PhD. Dr. Tuohy, Professor of Immunology, Molecular Medicine, and Pathology at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Staff in the Department of Immunology at the Cleveland Clinic, will present Development of a Prophylactic Breast Cancer Vaccine. Dr. Vincent K. Tuohy received his PhD in the Department of Pathology at the State University of New York, and completed his post-graduate training at Harvard Medical School. During his post-graduate training, Dr. Tuohy studied the immune response to the highly hydrophobic myelin proteolipid protein (PLP) and showed how an immune response to PLP was capable of inducing severe autoimmune demyelination of the central nervous system similar to what occurs in human multiple sclerosis. For his research efforts, Dr. Tuohy received the Harry Weaver Award from the National Multiple Sclerosis Society, the Peter W. Lampert Prize from the Society for Experimental Neuropathology, and the FIRST Award from the National Institute of Neurological Disorders and Stroke at the National Institutes of Health. Dr. Tuohy was recruited to the Cleveland Clinic in 1989 where he has extended his initial work on central nervous system autoimmunity by developing and characterizing autoimmune rodent models for deafness, heart failure, cystitis, prostatitis, ovarian failure, and breast failure. The ovarian and breast failure mouse models have been particularly useful in serving as novel cancer vaccination strategies for providing highly effective prevention and treatment of breast cancer and ovarian cancer. Dr. Tuohy serves as a consultant for the National Institutes of Health and the National Multiple Sclerosis Society, serves on the editorial board for several science journals, has trained over 20 postdoctoral fellows and graduate students, and has published over 85 manuscripts. Case CCC Annual Scientific Retreat The Case CCC Annual Scientific Retreat will be July 8-9 at Corporate College East. Details will be posted soon. FUNDING OPPORTUNITIES Pilot Project Grants: American Cancer Society IRG Awards The Case CCC is currently accepting applications for American Cancer Society Institutional Research Grant (IRG) awards. Pilot funding is available for projects in basic, clinical, prevention and control, behavioral, health services, and epidemiology cancer research with awards up to $30,000 for one-year cancer research projects that provide the basis for future independent grants. IRG pilot project grants are intended to support independent, self-directed investigators early in their careers (assistant professor or equivalent). Applicants for the pilot project grants should be within 6 years of their first independent research or faculty appointment and eligible to apply for an independent national competitive research grant, but may not currently hold such a grant. At the time of application, recipients of IRG pilot project grants must be citizens or noncitizen nationals of the United States or its possessions and territories, or must have been lawfully admitted to the United States for permanent residence at the time of application. Instructions, frequently asked questions, and application forms are available at http://cancer.case.edu. Contact Terri Daso, Cancer Center Administration (844-7252, tld6@case.edu) for more information. LOI Deadline: June 13 Application Deadline: July 5, 2011 Robert Wood Johnson Foundation Public Health Services and Systems Research Grant The Robert Wood Johnson Foundation seeks to expand the evidence base for effective public health policy and practice through investment in Public Health Services and Systems Research (PHSSR). PHSSR examines the organization, financing and delivery of public health services within a community and determines the links between the quality and performance of the public health system and population health outcomes. A web conference for interested applicants will be held April 27 at 3 pm. Registration is required. Proposal Deadline: May 24 ANNOUNCEMENTS Message from Dr. David Wald, Scientific Director, Hematopoietic Stem Cell Core Facility The Case Comprehensive Cancer Center is gathering information about anticipated research needs for the Hematopoietic Stem Cell Core Facility. Your responses will help us build a core facility that reflects the collective needs of cancer center members. Please visit http://www.zoomerang.com/Survey/WEB22C22WB5KZ7/ and complete the short survey. We appreciate your participation!	EVENTS All events are open to anyone interested in attending April 18 Pathology Research Seminar Claudio Soto, PhD Professor, Neurology University of Texas Medical Branch at Galveston Topic:** Infectious Proteins: Expanding the Prion Heresy 12 pm WRB 1-413 Physiology and Biophysics Seminar William Pearce, PhD Professor, Physiology Associate Director, Center for Perinatal Biology Loma Linda University Topic: Functional Maturation of the Fetal Vasculature: A Tale of Calcium, Myosin, VEGF, and miRNA 4 pm SOM E501 April 19 Cancer Biology Fellow Seminar Awad Jarrar, MD Research Fellow, Kalady Lab Cleveland Clinic Topic: Studying Chemoresistance in Colorectal Cancer: From Molecular Pathways to Cancer Stem Cells 11 am NC1-202 Cleveland Clinic Immunology Seminar Neil Greenspan, MD, PhD Professor, Pathology CWRU/UH Topic: Immunology, Evolution, and Logic: Reflections on Immunological Specificity 12 pm WRB 1-413 April 20 Developmental Therapeutics Program (DTP) Meeting canceled Hematology and Oncology Division Research Conference Lalitha Nayak, MD Fellow, Div. of Hem/Onc CWRU/UH Topic: Transcription Factor Kruppel-like Factor 2 (KLF2) Deficiency Promotes Platelet Hyperactivity and Vascular Thrombosis in Mice 8 am Lerner B-151 Immunology Invited Speaker Seminar Series Clifford Harding, MD, PhD Professor and Chair, Pathology CWRU Topic: TLR Signaling and Regulation of Immune Responses by Mycobacterium Tuberculosis 12 pm NC1-202 Cleveland Clinic NCRM Lunch and Learn Jed Johnson, PhD Nanofiber Solutions Topic: Next Generation 3D Cell Culture 12 pm WRB 2-136 Pathology Graduate Student Seminar Lachelle Weeks Gerson Lab, Div. of Hem/Onc CWRU/UH Topic: Loss of Uracil DNA Glysocylase (UDG) Potentiates Pemetrexed Cytotoxicity in Vitro and In Vivo 12 pm WRB 1-413 Cancer Imaging Program (CIP) Drug Delivery Focus Group Meeting Drs. Vinod Labhasetwar, Eben Alsberg and Horst von Recum will present a brief synopsis of their research and current critical needs in the field of drug delivery 2:30 pm Wearn B-37 April 21 Cancer Center Scientific Series: Immunology Anton Gorbachev, PhD Topic: Down-Regulation of CXCL9/Mig Expression in the Tumor Microenvironment as a Result of Immunoediting AND Neetu Gupta, PhD Topic: A Novel Signaling Link Between Ezrin and JNK Regulates Antigen-Dependent B Cell Survival AND Alex Huang, MD, PhD Topic: Measuring Immune Surveillance in Tissue Microenvironment 4-6:30 pm WRB 1-413 April 22 Cancer Center Research in Progress Seminar canceled Taussig Cancer Institute Grand Rounds canceled Hematology/Oncology Fellows Neal Meropol, MD Professor, Medicine-Hematology/Oncology CWRU/UH Topic: Building a Successful Career in Clinical Research 8 am Wearn 137 Cancer Center Seminar Series Vincent Tuohy, PhD Professor, Immunology, Molecular Medicine, and Pathology CWRU/Cleveland Clinic Topic: Development of a Prophylactic Breast Cancer Vaccine 12 pm BRB 105 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS Breast Cancer Detection and Management: Issues for 2011 May 20 Hilton Cleveland East Brochure Case CCC Annual Scientific Retreat July 8-9 Details to follow ADDITIONAL UPCOMING SEMINARS & EVENTS Midwest Blood Club 9th Annual Symposium April 21-22 Cincinnati Children's Hospital Medical Center Details 2011 Clinical and Translational Research and Education Meeting: ACRT/SCTS Joint Annual Meeting April 27-29 Omni Shoreham in Washington, DC Details Cincinnati Cancer Symposium Series: 2011 Symposium on NF-κB, Cancer, Obesity, and Inflammation May 1-4 Westin Hotel Cincinnati Details 4th International Symposium on Cancer Metastasis and the Lymphovascular System May 12-14 New York City Details 2nd Annual Department of Medicine Research Day May 16 12-5 pm Wolstein Research Building auditorium and lobby Details Race for the Place June 5 Beachwood Place Mall Details International Society for Stem Cell Research (ISSCR) Annual Meeting June 15-18 Toronto, Canada Details Cancer Health Disparities Summit 2011 July 13-15 Bethesda North Marriott Hotel in Rockville, Maryland Details 8th International Conference of the Society for Integrative Oncology: Innovating Integrative Oncology: New Science, New Solutions November 10-12 InterContinental Hotel Cleveland Details

PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
Avon Foundation Breast Cancer Research Program Cycle 2 LOI Deadline: May 6 Cycle 2 Full Proposal Deadline: July 5 Ovarian Cancer Research Fund Program Project Development Grants LOI Deadline: May 9 Ovarian Cancer Research Fund Liz Tilberis Scholars LOI Deadline: May 9 Ovarian Cancer Research Fund Ann Schreiber Research Training Programs of Excellence LOI Deadline: May 9 Uniting Against Lung Cancer 2011 Legacy Program for Advances in Lung Cancer Research Deadline: August 17 Lustgarten Foundation Fall 2011: Basic Research Innovator Awards Concept Proposal Deadline: September 14 Full Application Deadline: October 31	Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC) Deadline: Open AACR Scholar-in-Training Awards - Other Conferences and Meetings Deadline: Open International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open James S. McDonnell Foundation Collaborative Activity Awards Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities Predictive Multiscale Models for Biomedical, Biological, Behavioral, Environmental and Clinical Research (Interagency U01)(PAR-11-203)
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216-844-8317 phone 216-844-7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.