Case Comprehensive Cancer Center: Weekly Newsletter

Home | Back to newsletter main page


February 7, 2011
CASE CCC IN THE NEWS Gold Nanoparticles 'Make Anti-cancer Drugs More Effective' Daily News & Analysis - Feb 6, 2011 "We hope to lower the dosage by at least a factor of 10," said Clemens Burda, a professor of chemistry at Case Western Reserve University and senior author ... Running a Cancer Roadblock US News & World Report - Feb 4, 2011 ... of the body is one of the main reasons cancer kills, says Khalid Sossey-Alaoui, a cancer biologist at the Cleveland Clinic's Lerner Research Institute. ... Health Highlights: Gene Test May Someday Improve Prostate Cancer Treatment BusinessWeek - Feb 4, 2011 "It's early still but it's pretty exciting," Cleveland Clinic's Dr. Eric Klein told the AP. "This is a step in the right direction, without question. ... New Clinical Trial to Determine Ovarian Cancer Risks in African-American Women EurekAlert (press release) - Feb 1, 2011 ... treat, and assess both environmental and genetic risk factors in African American women," said Jill S. Barnholtz-Sloan, PhD, the study's principal ...said Steven Waggoner, MD, co-primary investigator on the study, Chief of Gynecologic Oncology at UH Case Medical Center and Associate Professor at Case ... Brain Tumor Surgery KIMT - Feb 1, 2011 Neurosurgeon, Gene Barnett, MD says, "It should make us better able to remove brain tumors, get better long term results and do it in as safe as possible ... NEW MEMBERS CORNER Please join us in welcoming the newest members of the Case CCC: Shideng Bao, PhD Normal and Neoplastic Stem Cells Program Brian Gastman, MD GU Malignancies Program Meg Gerstenblith, MD Cancer Genetics Program Mei Zhang, PhD Developmental Therapeutics Program MARK YOUR CALENDARS Cancer Center Seminar Series: Image Guided Drug Delivery in Cancer Therapy Friday, February 11 12-1 pm Frohring Auditorium - BRB 105 Please join us Friday, February 11 at the next Cancer Center Seminar Series featuring Agata Exner, PhD. Dr. Exner, Associate Professor of Radiology and Biomedical Engineering at CWRU, will present Image Guided Drug Delivery in Cancer Therapy. Dr. Exner is an innovator in the fields of drug delivery and image guided intervention leading an inter-disciplinary team of researchers at the Case Center for Imaging Research. Her research focuses on development of minimally invasive drug delivery approaches to cancer management, and is primarily supported by the NCI and National Institute for Biomedical Imaging and Bioengineering. Dr. Exner received her PhD in Biomedical Engineering from CWRU. The Exner Laboratory for Image Guided Therapeutics has been working in the area of image-guided drug delivery since its inception in 2003. Their efforts have resulted in several techniques for noninvasive characterization and modulation of drug delivery on a broad scale, from in situ forming implants to multifunctional nanoparticles. They currently have two primary collaborative projects. The first focuses on exploring the use of ultrasound to develop a comprehensive image-guidance approach for the development and application of in situ forming implants for intratumoral chemotherapy delivery. The second project engineers ultrasound contrast agents on the nano-scale for ultrasound-guided delivery of a bioactive agent for cancer hyperthermia treatment. Cell Death Regulation Program Meeting The leaders of the Case CCC Cell Death Regulation Program (Program 2) invite you to this month's program research meeting Thursday, February 10 from 4-6 pm in WRB 3-136. This month's meeting will focus on autophagy. Speakers: Brain Rubin, MD, PhD- Associate Professor, Anatomic Pathology, Molecular Genetics, CWRU/Cleveland Clinic Clark Distelhorst, MD- Professor, Medicine-Hem/Onc, Pharmacology, CWRU/UH Nancy Oleinick, PhD- Professor, Radiation Oncology, CWRU/UH Refreshments will be provided and parking validated. Please contact Kristin Waite with any questions. Integrated Genomics Shared Resource (IGSR) Lecture As part of its planned vigorous outreach program, the Cancer Center's newly formed Integrated Genomics Shared Resource (IGSR) will host a talk by speaker Mark Adams, PhD on RNA-Sequencing, Tuesday, February 15 at 2 pm in BRB 105. This promises to be a highly informative lecture and should interest anyone who is curious about or contemplating projects involving quantitation of mRNA, miRNA, snRNA etc using the latest deep sequencing technologies. Dr Adams' address will be broad, covering such topics as: the challenges, technical limitations, cost, data storage and analysis. For further information on this and other upcoming IGSR-sponsored presentations, please contact Patrick Leahy, Scientific Coordinator, Integrated Genomics Shared resource (ISGR) at 368-0761 or Patrick.Leahy@case.edu. Is Cancer Curable? Drs. Stan Gerson and Derek Raghavan will discuss cancer treatment at the upcoming Is Cancer Curable, February 17 at the Executive Caterers Corporate Club. The event is part of the monthly television series of Corporate Club Luncheon Programs dealing with issues that impact the lives of people in Northeastern Ohio. The program will begin with an interview session by WKYC TV-3 Medical Reporter Monica Robbins, and will conclude with audience questions. Lunch is included in the cost of registration. Details and registration information are available on the Executive Caterers Corporate Club website. Fourth Annual Translational to Clinical (T2C) Wound Care Conference The Fourth Annual Translational to Clinical (T2C) Wound Care Conference will be held April 8-9 at the Ohio State University Ohio Union in Columbus. The conference features lectures by top experts from throughout the country who discuss stem and progenitor cells, contrast tissue regeneration with repair, and describe the latest advances in wound care. Dr. Christopher Lengner from the Whitehead Institute at MIT will present the Regenerative Medicine Distinguished Lecture on iPS Technology in Regenerative Medicine. Graduate students, MD/PhD students, medical students, postdoctoral trainees, clinical residents or fellows, and undergraduate students enrolled in training programs are invited to participate in the conference poster session. Research should address tissue injury, repair and inflammation related to all organs. The early-bird deadline for submissions is February 15. Students and fellows who submit abstracts by the early bird deadline will be recognized with a registration fee waiver. All submitted abstracts will be discussed in a poster session that will be judged by a panel of national experts. Best poster awards will be given in the following categories: undergraduate, graduate, medical student, resident and clinical fellow, postdoctoral fellow and assistant-professor-rank faculty. Case CCC Annual Scientific Retreat The Case CCC Annual Scientific Retreat will be July 8-9, 2011. Further details will be released in the coming months. FUNDING OPPORTUNITIES Multiple Myeloma Research Foundation (MMRF) The Multiple Myeloma Research Foundation (MMRF) seeks proposals for the following funding opportunities: 2011 Senior Research Award Program, an initiative supporting researchers who have more than five years experience in blood cancer research. The goal of this initiative is to accelerate the development of therapeutic approaches for myeloma. Deadline: February 15 2011 Research Fellow Award Program, an initiative supporting researchers with less than five years experience (post highest degree obtained, doctorate or equivalent) working under the supervision of a research mentor in the multiple myeloma field. The goal of this initiative is to help support young investigators studying in the field of multiple myeloma while advancing the understanding of myeloma disease biology, treatment and drug resistance. Deadline: March 29 Conquer Cancer Foundation of ASCO The Conquer Cancer Foundation of ASCO is accepting applications for the following opportunities: ASCO Medical Student Rotation The ASCO Medical Student Rotation, funded by Susan G. Komen for the Cure®, provides 8- to 10-week clinical or clinical research rotations for US medical students from populations underrepresented in medicine who are interested in pursuing oncology as a career. To qualify, applicants must be enrolled in a DO or MD US medical school program and be of an underrepresented population as defined by the program eligibility criteria. Candidates must be US citizens, US nationals, or permanent residents. Candidates must also demonstrate an interest in pursuing oncology as a career and have a record of good academic standing. Deadline: February 21 ASCO Resident Travel Award The ASCO Resident Travel Award, funded by Susan G. Komen for the Cure®, provides financial support for residents from underrepresented populations to attend ASCO's Annual Meeting. The intention of this award is to attract residents from underrepresented populations to a possible career in one of the oncology specialties. This travel award will allow the recipients to travel to the ASCO Annual Scientific Meeting, where they will have an opportunity to meet oncologists and to understand the career possibilities in the is area. To qualify, applicants must be enrolled in an ACGME-accredited residency program required for future training in a cancer related subspecialty (i.e. Internal Medicine considering Med/Onc, Surgery considering Surg/Onc) and be of an underrepresented population as defined by the program eligibility criteria. Candidates must be US citizens, US nationals or permanent residents. Candidates must demonstrate an interest in pursuing oncology as a career as well as a record of good academic standing. Deadline: February 21 ANNOUNCEMENTS Case CCC Members Named AAAS Fellows In December 2010, 503 individuals were elected as Fellows of the American Association for the Advancement of Science (AAAS). The Case CCC is honored to have two members recognized for their contributions to science and technology: Dr. Thomas Hamilton for the Medical Sciences, and and Dr. James Anderson for Engineering. In addition, Dr. Eileen White, who has served on the Case CCC External Advisory Board since 2009, was also recognized for her work in the Medical Sciences. Congratulations to all! Mark Smith Memorial Service An on-campus memorial service for Mark A. Smith, PhD, professor of pathology, is scheduled for Monday, February 14 at 5:15 pm. The service will be held in the Amasa Stone Chapel at 10940 Euclid Avenue (Euclid Avenue just west of Adelbert Road). A reception will follow in the first floor of Crawford Hall. For questions or additional information, please contact: Kathy Malone at 368-3109 or kwm4@case.edu or Barbara Nicol at 368-5515 or bxn4@case.edu. NASA Space Radiation Summer School Applications are now being accepted for the NASA Space Radiation Summer School, June 6–24. This program is designed for graduate students, postdoctoral fellows, and faculty with an interest in radiation biology. Both foreign nationals and US citizens may apply to the program. All selected students must satisfy Brookhaven National Laboratory safety and security requirements in order to be admitted. In addition, due to the intense nature of the three-week course, selected students must possess oral and written proficiency in the English language. Deadline: February 13 iMedRIS Training New cancer research protocols requiring IRB review will be submitted, reviewed and stored electronically using the Case Cancer IRB electronic, web-based submission and review database provided by iMedRIS™ Data Corporation. Part 4 (How to Respond to Stipulations) and Part 5 (How to submit Amendments) of the iMedRIS™ training sessions will be offered through February. All interactive training will be accessible online using Adobe Acrobat Connect and telephone conference line and can be accessed at personal workstations. For more information or to download training guides, please visit the iRIS Training Page. To register, please contact Mariesa Malinowski or Mark Tennant.	EVENTS *All events are open to anyone interested in attending February 7 Physiology and Biophysics Seminar canceled* Pathology Seminar Barbara Bedogni, PhD Assistant Professor, Biochemistry CWRU/UH Topic: Notch and ERBB Signaling Cross-Talk in Melanoma 12 pm WRB 1413 February 8 Cancer Biology Seminar Ichiro Nakano, MD, PhD Associate Professor, Neurological Surgery Ohio State University Topic: Therapeutic Development Targeting Glioblastoma Stem Cells 11 am NC1-202 Cleveland Clinic Taussig Cancer Institute Core Curriculum Series Topic: Bioethics 12 pm R3-002 Cleveland Clinic February 9 Hematology and Oncology Division Research Conference Neal Meropol, MD Professor, Medicine-Hematology/Oncology CWRU/ UH Topic: Use of Genomics to Select Treatment for Patients with Colon Cancer 8 am Lerner Tower B-151 Breast Cancer Retreat 9 am - 1 pm Dively Bldg 214 Agenda Department of Immunology Faculty Research in Progress Seminar Wink Baldwin, MD, PhD Staff, Immunology Cleveland Clinic Topic: Transplant Rejection: Immune Responses Involving Big Versus Small Vessels in Organ Transplant 12 pm NC1-202 Cleveland Clinic Molecular Cardiology Faculty Seminar Series Khalid Sossey-Alaoui, PhD Project Staff, Molecular Cardiology Cleveland Clinic Topic: Making WAVES as a Mechanism for How MicroRNAs Control EMT and Cancer Metastasis 3 pm NC1-202 Cleveland Clinic NCRM Seminar Stan Gerson, MD Director, NCRM Director, Case CCC Director, Seidman Cancer Center Professor, Medicine-Hem/Onc CWRU/UH Topic: NCRM in 2011, the Best Science, Collaborations and New Initiatives 4:30 pm Cleveland Clinic NA1-139 February 10 NCRM Lunch and Learn Yukang Zhao Senior Manager, New Product Initiatives Arteriocyte Topic: Nanofiber Based Ex Vivo Expansion of HSC for Pre-Clinical and Clinical Application 12-1:30 pm WRB 2-136 Neurosciences Seminar Paul Tesar, PhD Assistant Professor, Genetics CWRU Topic: Directing the Oligodendrocyte Lineage 12:10 pm BRB 105 Cell Death Regulation Program Meeting Brain Rubin, MD PhD Clark Distelhorst, MD Nancy Oleinick, PhD Topic: Autophagy 4-6 pm WRB 3-136 February 11 Hematology/Oncology Fellows Jennifer Eads, MD Fellow, Div. of Hem/Onc CWRU/ UH Topic: TBD 8 am Wearn 137 Taussig Cancer Institute Grand Rounds Vincent Tuohy, PhD Professor, Molecular Medicine Staff, Immunology CWRU/Cleveland Clinic Topic: Development of a Prophylactic Breast Cancer Vaccine 8 am R3/002-003 Cleveland Clinic Cell Biology Seminar Series John M.L. Ebos, PhD Topic: Disease Progression after Antiangiogenic Therapy: Implications for Metastasis 10 am NC1-202 Cleveland Clinic Cancer Center Seminar Series Agata Exner, PhD Associate Professor, Radiology and Biomedical Engineering CWRU/ UH Topic: Image Guided Drug Delivery in Cancer Therapy 12 pm BRB 105 Department of Neurosciences Special Seminar James Fawcett, PhD Professor, Neuroscience Cambridge University Centre for Brain Repair Topic: Targeting the Extracellular Matrix to Promote Regeneration and Plasticity 12 pm SOM E501 please note location change Cancer Center Research in Progress Seminar John Pink, PhD Assistant Professor, General Medical Sciences (Oncology) Topic:** The Search for Biomarkers and Mediators of Estrogen Independence in Breast Cancer 4 pm WRB 3-136 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS Breast Cancer Detection and Management: Issues for 2011 May 20 Hilton Cleveland East Details to follow ADDITIONAL UPCOMING SEMINARS & EVENTS Active Living Research Annual Conference February 22-24 San Diego, CA Details 14th Annual Meeting of the Translational Research Cancer Centers Consortium 2011 February 24-26 Seven Springs Mountain Resort, Seven Springs, PA Details Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals March 4-5 Las Vegas, Nevada Details 4th Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science March 28-29 Bethesda North Marriott Hotel & Conference Center in Bethesda, Maryland Details Fourth Annual Translational to Clinical (T2C) Wound Care Conference April 8-9 Ohio Union, Ohio State University, Columbus Details 2011 Clinical and Translational Research and Education Meeting: ACRT/SCTS Joint Annual Meeting April 27-29 Omni Shoreham in Washington, DC Abstract Deadline: December 16 Details Cincinnati Cancer Symposium Series: 2011 Symposium on NF-κB, Cancer, Obesity, and Inflammation May 1-4 Westin Hotel Cincinnati Details 4th International Symposium on Cancer Metastasis and the Lymphovascular System May 12-14 New York City Abstract Submission Deadline: March 15 Details International Society for Stem Cell Research (ISSCR) Annual Meeting June 15-18 Toronto, Canada Details Cancer Health Disparities Summit 2011 July 13-15 Bethesda North Marriott Hotel in Rockville, Maryland Details 8th International Conference of the Society for Integrative Oncology November 10-12 InterContinental Hotel Cleveland Details

PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
2011 Dr. Paul Janssen Award for Biomedical Research Deadline: February 15 Leukemia Research Foundation Deadline: February 15 ACS Cancer Research Fellowship Deadline: February 16 CTSC Translational Research through Community-Academic Partnerships and Community Research Mandatory LOI: February 17 Full Application Deadline: April 4 Prostate Cancer Foundation (PCF)-Honorable A. David Mazzone Special Challenge Award Research Program Deadline: February 24 Leukemia and Lymphoma Society Translational Research Program Mandatory LOI Deadline: March 1 Full Application Deadline: March 15 Cancer Research Institute Investigator Award Deadline: March 1 Lustgarten Foundation Spring 2011: Translational Research Innovator Awards Concept Proposal Deadline: March 14 Full Application Deadline: May 2 James S. McDonnell Foundation 21st Century Science Research Awards Deadline: March 15	National CENter for ReGenerAtive Medicine UnderGraduate StudEnt (ENGAGE) Summer Program Deadline: March 31 Avon Foundation Breast Cancer Research Program Cycle 2 LOI Deadline: May 6 Cycle 2 Full Proposal Deadline: July 5 Lustgarten Foundation Fall 2011: Basic Research Innovator Awards Concept Proposal Deadline: September 14 Full Application Deadline: October 31 Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC) Deadline: Open AACR Scholar-in-Training Awards - Other Conferences and Meetings Deadline: Open International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open James S. McDonnell Foundation Collaborative Activity Awards Application Deadline: Open
NIH BULLETIN – Notices and Funding Opportunities Delays in Grant Application Submission due to Widespread Blizzard (NOT-OD-11-040) Notice of Availability of Administrative Supplements for U.S. - China Biomedical Collaborative Research on Cancer, Allergy, Immunology, and Infectious Diseases including HIV/AIDS and its Co-morbidities (NOT-CA-11-003) Notice of Correction of Expiration Dates for PAR-09-224 Improving Diet and Physical Activity Assessment (R01) and PAR-09-225 Improving Diet and Physical Activity Assessment (R21) (NOT-CA-11-006) SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics Toward Commercialization (R44) (RFA-CA-11-002) Lasker Clinical Research Scholars Program (SI2) (RFA-OD-11-001)
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216-844-8317 phone 216-844-7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.