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Case Comprehensive Cancer Center Newsletter

January 3, 2011


Exercise Your Resolve to Get Healthier
Akron Beacon Journal (blog) - Jan 1, 2011
Dr. Neal J. Meropol, chief of the Division of Hematology and Oncology, University Hospitals Case Medical Center in Cleveland. ''Each year millions of people ...


NCI Announces Plans to Reinvigorate Clinical Trials

The National Cancer Institute (NCI) has announced major changes to be made in the long-established Clinical Trials Cooperative Group Program that conducts many of the nationwide trials of new cancer therapies. In a major transformation, NCI intends to consolidate the nine groups that currently conduct trials in adult cancer patients into four state-of-the-art entities that will design and perform improved trials of cancer therapies. These changes are designed to provide greater benefits for cancer patients and more information for researchers. These moves come in response to an NCI-requested April 2010 report from the Institute of Medicine (IOM), which called for a series of changes to the cooperative groups program, including restructuring.

Click here to view the entire article from NCI.


ACS Cancer Research Fellowship

Applications are now being accepted for the ACS Cancer Research Fellowship, which is intended to attract outstanding clinicians and scientists in Ohio to explore and pursue careers in oncology upon completion of their specialty training. The program is specifically designed to encourage Ohio clinicians to engage in basic or clinical academic research. This fellowship is intended for first-time applicants with an MD, DO, DDS, or PhD in Nursing, and others not already on a research track. It is not intended for PhD candidates already on a research track.

Deadline: February 16

Mary Kay Foundation Cancer Research Grant Program

The Mary Kay Foundation has released a Call for Applications for their Cancer Research Grant Program. This non-profit public foundation focuses on funding research for innovative grants for translational research in ovarian, uterine, breast or cervical cancer. Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer.

Only ONE application per institution is allowed. Investigators interested in applying must submit their biosketch and a one-paragraph description to cancer@case.edu by Wednesday, January 5.

Internal Deadline: January 5
External Deadline: February 4

Damon Runyon Cancer Research Foundation Clinical Investigator Award

CWRU SOM has been invited to nominate up to three individuals for the Damon Runyon Cancer Research Foundation Clinical Investigator Award. This award supports young physician-scientists conducting patient-oriented cancer research, with a goal of increasing the number of physicians capable of moving seamlessly between the laboratory and the patient's bedside in search of breakthrough treatments.

New this year is a novel partnership with the National Institutes of Health (NIH) and the National Cancer Institute (NCI), which opens access to the NIH Clinical Center (CC) to Damon Runyon Clinical Investigators. The goal of this partnership is to use the special talent, expertise and resources of the participants to undertake pilot studies of specific diseases and to develop collaborative partnerships that accelerate clinical and translational cancer research, and thereby improve human health. See the website for more information.

If you are interested in applying for this award, please submit the following materials to cancer@case.edu by Monday, January 10: biosketch and a one-paragraph description of how your research fits the description of "Clinical Research" as described by the Damon Runyon Foundation.

Internal Deadline: January 10
External Deadline: March 1

Interinstitutional Basic, Clinical and Translational Research Projects in Cancer

The Case CCC will provide seed money to foster collaborations and promote and increase institution-wide capacity and competitiveness in basic, clinical or translational research that is aligned with the Cancer Center Scientific Programs and spans the institutions of the Case CCC. 2-3 awards of $75,000 - $100,000 will be made.

Faculty at all levels with interests in cancer research are encouraged to apply. Proposals require a minimum of two PIs: one from Case/UH and one from Cleveland Clinic. Proposals must involve new collaborative work with no joint publications or grants related to the current project. Applications will be submitted through http://webgrants.case.edu.

Deadline: January 18, 2011

Complete information is available on the Cancer Center website.


Clinical Assay Development Program (CADP)

The NIH has recently unveiled a new program, the Clinical Assay Development Program (CADP) designed to provide support and expertise to aid in the transition of predictive or prognostic cancer research assays to clinically validated, robust, "CLIA-approved" assays. This program is similar in scope and design to the RAID program for drug development.

The assay to be developed must measure predictive or prognostic markers, assays measuring diagnostic markers will not be considered for this program. The primary biospecimens to be utilized will be archived, formalin fixed, paraffin embedded tissues, however, assays utilizing other biospecimens will be acceptable if they are sufficiently compelling. One important eligibility criterion requires that the assay must be able to be performed with instrumentation and techniques available in standard clinical labs.

The deadline for the first round of applications is January 21, 2011.

For additional information, or to request assistance in development of an application please contact: John Pink (jrp16@cwru.edu), Director; Translational Research Core Facility, Case Comprehensive Cancer Center.



**All events are open to anyone interested in attending

January 3

January 4

Taussig Cancer Institute Core Curriculum Series
Ernest Borden, MD
Professor, Hematology & Medical Oncology, Cancer Biology
CWRU/ Cleveland Clinic
Topic: Sarcomas: 40 Years of Progress
12 pm R3-002 Cleveland Clinic

January 5

Hematology and Oncology Division Research Conference canceled

January 6

Aging-Cancer-Energetics Seminar
Siran Koroukian, PhD
Associate Professor, Epidemiology & Biostatistics
Topic: Multimorbidity and Cancer Stage in Nursing Home Residents
4 pm BRB 732

Physiology and Biophysics Seminar
Tomasz L. Religa, PhD
Postdoctoral Fellow, Molecular Genetics
University of Toronto
Topic: The Gating Mechanism of an Archaeal Proteasome
4 pm SOM E501

January 7

Hematology/Oncology Fellows Conference
Brad Clifford, MD
Fellow, Medicine- Hem/Onc
Topic: Targeted Therapy in Metastatic Renal Cell Carcinoma
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Roger Macklis, MD
Professor, Radiation Oncology
CWRU/ Cleveland Clinic
Topic: Why We Must Continue to Include Radiotherapy in the Lymphoma Play Book
8 am R3/002-003 Cleveland Clinic

Cell Biology Seminar Series
Hung-Ying Kao, PhD
Associate Professor, Biochemistry
Topic: The Peptidyl-prolyl Cis/trans Isomerase Pin1: Role in Cancer and Therapeutic Implications
10 am NC1-202 Cleveland Clinic

Cancer Center Seminar Series
Mikkael Sekeres, MD, MS
Associate Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: The Epidemiology of Myelodysplastic Syndromes: 2010
12 pm BRB 105

Cancer Center Research in Progress Seminar
Marvin Nieman, PhD
Assistant Professor, Medicine
Topic: Protease Activated Receptor Dimers
4 pm WRB 3-136


Case CCC Calendar

LRI Calendar


Breast Health Update: Issues for 2011
May 20
Hilton Cleveland East
Details to follow

8th International Conference of the Society for Integrative Oncology
November 10-12
InterContinental Hotel Cleveland
Details to follow


Active Living Research Annual Conference
February 22-24, 2011
San Diego, CA
Call for Abstracts Deadline: August 6

Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals
March 4-5, 2011
Las Vegas, Nevada

4th Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science
March 28-29, 2011
Bethesda North Marriott Hotel & Conference Center in Bethesda, Maryland

2011 Clinical and Translational Research and Education Meeting: ACRT/SCTS Joint Annual Meeting
April 27-29, 2011
Omni Shoreham in Washington, DC
Abstract Deadline: December 16

Cancer Health Disparities Summit 2011
July 13-15, 2011
Bethesda North Marriott Hotel in Rockville, Maryland


Prostate Cancer Foundation (PCF) 2011 Creativity Awards
Deadline: January 13

Interinstitutional Basic, Clinical and Translational Research Projects in Cancer
Deadline: January 18

Avon Foundation Breast Cancer Research Program
Cycle 1 LOI Deadline: January 21
Cycle 1 Full Proposal Deadline: March 11

Prostate Cancer Foundation (PCF)-Honorable A. David Mazzone Special Challenge Award Research Program
Deadline: February 24

AICR Research Grant Program
External LOI Deadline: January 25
External Full Application Deadline: May 2

AICR Investigator Initiated Grants (IIGs)
LOI Deadline: January 25
Full Application Deadline: May 2

AICR Matching Grants
LOI Deadline: January 25
Full Application Deadline: May 2

AICR Postdoctoral Awards (PDAs)
LOI Deadline: January 25
Full Application Deadline: May 2

ACS Joseph S. Silber Student Research Fellowship
Deadline: January 28

2011 Lasker Medical Research Awards
Nomination Deadline: February 1

2011 Jane Coffin Childs Memorial Fund for Medical Research Fellowship Awards
Deadline: February 1

Leukemia Research Foundation
Deadline: February 15

James S. McDonnell Foundation 21st Century Science Research Awards
Deadline: March 15

Avon Foundation Breast Cancer Research Program
Cycle 2 LOI Deadline: May 6
Cycle 2 Full Proposal Deadline: July 5

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation Collaborative Activity Awards
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Continuation of the National Mesothelioma Virtual Bank for Translational Research (U24) (RFA-OH-11-002)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.