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Case Comprehensive Cancer Center Newsletter

August 30, 2010

MESSAGE FROM THE DIRECTOR

Dear Cancer Center members and investigators:

The Cancer Center announces the first scientific series seminar of the fall semester. The fall is always an exciting and revitalizing time around campus, and what better way to kick off a new academic year than catching up on the innovative research being conducted by your colleagues?

Today's Case CCC Scientific Series will feature updates on research collaborations made possible by pilot funding through the Multi-Investigator Grant Initiative to Promote the Basic Science Scientific Focus Group Areas of the Cancer Center. Three of the funded teams will be presenting:

  • Cathleen Carlin, PhD and Zhenghe Wang, PhD: Cross-Talk Between EGFR and PTPN14 During Integrin-Regulated Cell Adhesion: Role for STAT3 [Cancer Cell Signaling Program]
  • Shigemi Matsuyama, PhD and Alex Almasan, PhD: Cell Death Decision Mechanism by the Interaction of Factors Regulating Cell Cycle (CyclinE) and DNA Repair (Ku70) [Cell Death Regulation Program]
  • Saba Valadkhan, PhD and Phil Howe, PhD*: Characterization of the Anti-Apoptotic Activity of a TGF-B Responsive Non-Coding RNA [Cancer Cell Signaling Program]
    *project co-investigator; not presenting

These projects represent terrific collaborative science that address important basic science questions in cancer. The talks will all be outstanding from highly qualified investigators. We will have a discussion after each talk and at the end as we look towards broader applications and impact of these studies.

Please join us today, August 30 in Wolstein Auditorium. Presentations start at 4 pm, and should end around 5:30, followed by a discussion until 6 and a reception. For those of you who will come over for the seminar, parking validation will be gladly provided.

I hope to see you all there!

Stan Gerson, MD
Director, Case Comprehensive Cancer Center


CASE CCC IN THE NEWS

This Week on Kaleidoscope
WEWS5 - Aug 22, 2010
Director of University Hospitals Cancer Center Dr. Stanton Gerson and Director of Institutional Relations and Development Mark Cotleur discuss the new cancer hospital which will open next spring...


ANNOUNCEMENTS

TEMPLATES

 

stacked logo

The official Case CCC logo is available on the templates page of the Cancer Center website. Co-branded PowerPoint templates are also available on that page.

As a reminder, the NCI-designated Comprehensive Cancer Center logo may only be used in conjunction with the Case CCC logo.


FUNDING OPPORTUNITIES

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)

Message from Dr. Ernest Borden

The CTC/CEC core has initiated several investigator-initiated pilot studies and has begun to see planning for those which will be externally funded. We continue to encourage you, however, to develop new ideas for exploring and validating this technology. In addition to quantitation of these rare circulating cells, we are also now ready to undertake isolation of macromolecules for analysis. The isolated preparations will be provided back to you for assessment of expression in your laboratory or that of a collaborator.

These proposals should involve pilot studies for which technical feasibility and preliminary data needs to be established in order to lead to external funding and would normally be for evaluation of 10-20 samples. We will require the following information (limited to 1 page) for consideration for pilot studies:

  1. PI
  2. Study Title and Objective/Rationale (Tumor, CEC or CTC, cell quantitation or RNA)
  3. Eligible patients; desired number of samples
  4. Plans for obtaining external support (NIH, pharma, foundation based) for definitive study
  5. Contact information for research RN for scheduling and consenting purposes

If you have any questions please do not hesitate to discuss with John Pellecchia or Ernest Borden. Please submit your 1 page proposals to John Pellecchia. Final approval to proceed with your pilot study will be granted by Derek Raghavan and Ernest Borden and should normally be available within a week of submission.

Choose Ohio First Scholarship And Tomas & Evelyn James Fellowship In Bioinformatics, Computational Biology and Medical Informatics

The primary objective of the Choose Ohio First Scholarship (COF) Program is to support increased higher education participation and success of Ohio students in bioinformatics, computational biology and medical informatics, through the development and implementation of innovative curricular and programs, and in so doing, to advance the economic growth of the state.

Both undergraduate and graduate students who are residents of Ohio, with a minimum GPA of 3.0, and have a background compatible with academic excellence and leadership development in Biomedical Informatics are eligible to apply.

Deadline: September 15


CALL FOR ABSTRACTS

2011 Clinical and Translational Research and Education Meeting: ACRT/SCTS Joint Annual Meeting

Abstracts are now being accepted for the ACRT/SCTS Joint Annual Meeting, April 27-29, 2011 at the Omni Shoreham in Washington, DC. This meeting boasts integration between disciplines and shared successes from bench to bedside-Embracing the Full Spectrum of Translational Research.

Submission Deadline: December 16

EVENTS

calendar

**All events are open to anyone interested in attending

August 30

Taussig Cancer Institute Core Curriculum Series
Keith McCrae, MD
Professor, Hematologic Oncology & Blood Disorders
CWRU/ UH
Topic: ITP
12 pm R3-002 Cleveland Clinic

Pathology Research Seminar
Wenquan Zou, MD, PhD
Assistant Professor, Pathology
CWRU/ UH
Topic: Silent Prion and Its Pathophysiology
12 pm WRB 1413


August 31


September 1

ICC Grand Rounds
Smitha Krishnamurthi, MD
Assistant Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Metastatic Colorectal Cancer
8 am Lerner Tower B-151


September 2


September 3

Taussig Cancer Institute Grand Rounds Canceled

Hematology and Oncology Fellows
Alvin Schmaier, MD
Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Thrombotic Disorders
8 am Wearn 137

Cancer Center Research in Progress Seminar
Amar Desai
Graduate Student, Gerson Lab, Div. of Hem/Onc
CWRU/ UH
Topic: Role of Exo1 in DNA Double Strand Break and Mismatch Repair: Implications for Improved Radiotherapy in Cancer
4 pm WRB 3-136

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Cancer Center Scientific Series
August 30
4-7 pm WRB 1-413

Cancer Center Scientific Series
November 8
4-7 pm WRB 1-413

ADDITIONAL UPCOMING SEMINARS & EVENTS

Clinical Proteomic Technologies for Cancer (CPTC) 2010 Annual Meeting
September 8-9
Bethesda North Marriott Hotel & Conference Center, MD
Details

2010 caBIG Annual Meeting: Building a Collaborative Biomedical Network
September 13-15
Washington, DC
Details

Oncology Congress
October 15-17
San Francisco, CA
Details

2010 Cleveland Nanomedicine Summit
October 18-19
InterContinental Hotel, Cleveland, OH
Clinical and research abstracts will be accepted through October 1 (please note new deadline)
Details

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN
Details

ASCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer
October 18-20
Hollywood, FL
Call for Abstracts

Graft versus Host Disease Conference
November 4
Corporate College East, Cleveland, OH
Details

Active Living Research Annual Conference
February 22-24, 2011
San Diego, CA
Call for Abstracts Deadline: August 6
Details


CASE CCC SEED FUNDING

Request for Proposals: Cancer Stem Cell and Cancer Originating Cell Research Projects

The Case Comprehensive Cancer Center will provide seed money to foster collaborations and to promote and increase institution-wide capacity and competitiveness in cancer stem cell and cancer originating cell based research. Four awards of $50,000 will be made to investigators who intend to gather preliminary data to be used in seeking future independently funded programs and support. Case Comprehensive Cancer Center members with a faculty appointment at all levels (eligible to apply for independent nationally competitive research grants) are encouraged to apply. Proposals from both junior and senior investigators are encouraged. Postdoctoral fellows, graduate students and research associates are not eligible to apply for these pilot grants.

It is expected that these grants will represent new initiatives, not otherwise funded in new areas of cancer stem cell research. Use of animal models of human disease, primary cancer stem cells and cancer originating cells isolated from human cancers, development of novel cell lines such as iPS of human cancers, and methods development for the isolation of cancer stem cells and cancer originating cell based would be responsive. The NIH ARRA award mechanism will be the source of funds for 2 awards, with matching funds for the additional two awards. Investigators should identify the Cancer Center Scientific Program under which this pilot application is submitted and have a letter from the Program Leader acknowledging the programmatic alignment. Program Leaders can be found on the Cancer Center web site.

Deadline: September 10

Details are available on the cancer center website.

Request for Proposals: Basic, Clinical, or Translational Human Tissue Based Cancer Research Projects

The Case CCC will provide seed money to foster collaborations and to promote and increase institution-wide capacity and competitiveness in basic, clinical or translational human tissue based research.

Three awards of $50,000 and three awards at $20,000 apiece will be awarded to investigators who intend to gather preliminary data to be used in seeking future independently funded programs and support.

Case CCC members with a faculty appointment at all levels (eligible to apply for independent nationally competitive research grants) are encouraged to apply. Proposals from both junior and senior investigators are encouraged. Postdoctoral fellows, graduate students and research associates are not eligible to apply for these pilot grants. It is expected that these grants will represent collaborative efforts between lab based or quantitative science-based and clinical investigators, likely a clinician who is a member of the disease team of the tissue research in question.

Deadline: September 10

Details are available on the cancer center website.



MARK YOUR CALENDARS

SU2C

Stand Up to Cancer (SU2C), a new initiative created with a focus on funding high impact cancer research, is getting ready for their next telecast on September 10 at 8 pm. The broadcast will be dedicated to the 12 million U.S. cancer survivors and illustrate how groundbreaking research can change the tide in the fight against the disease. This year's telecast will feature live performances from legendary recording artists and stars in film, television, and sports. It will focus not only on scientific research, but also on survivorship and how patients can have quality of life after diagnosis and treatment. Viewership is vital because donations from the public will sustain this critical cancer research.

Third Annual Personalized Health Care National Conference

Registration is now open for "Advancing Predictive, Preventive, Personalized and Participatory (P4) Medicine," October 14-15 at The Ohio State University. The Third Annual Conference on Personalized Medicine features internationally renowned experts and leaders in personalized medicine, including keynote speakers Dr. Leroy Hood of the Institute for Systems Biology, Dr. Ralph Snyderman of Duke University and Dr. Greg Downing of the U.S. Department of Health and Human Services. The keynote speakers together with a large panel of academic and industry experts will share their insights on the latest developments and the future of personalized medicine. The major theme of the conference will focus on advancing the development of the P4 Medicine paradigm: predictive, preventive, personalized and participatory healthcare. This new paradigm will involve developing innovations in the health care delivery model, patient engagement, applications of genetics/genomics in clinical medicine, breakthroughs in science and technologies in healthcare, and the challenges of making personalized health care a reality. This conference will bring together academic leaders, industry experts, government policy makers and health care providers from around the nation to discuss the latest developments in personalized medicine research and the challenges of translating these discoveries into clinical practice.


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: extended to August 31

IOTF Cancer Prevention Fellows
Application Deadline: September 1

ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure
Required LOI Deadline: September 1

Susan G. Komen for the Cure Postdoctoral Fellowships
Pre-Application Deadline: September 15
Full Application Deadline: January 5, 2011

Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research
Pre-Application Deadline: September 15
Full Application Deadline: January 5, 2011

Leukemia and Lymphoma Society Scholar Awards
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Scholars in Clinical Research Awards
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Special Fellows
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Special Fellows in Clinical Research (SFCR) Awards
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Fellows Awards
Required LOI Deadline: September 15

Raymond and Beverly Sackler AACR Fellowships for Ileal Carcinoid Tumor Research
Deadline: September 15

Caring for Carcinoid Foundation–AACR Grants for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research
Deadline: September 15

DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award
Pre-Application Deadline: September 15
Application Deadline: September 29


William Lawrence & Blanche Hughes Foundation
Deadline: September 16

DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award
Application Deadline: September 29

DOD Peer Reviewed Cancer Research Program (PRCRP) Idea Awards
Application Deadline: October 20

DOD Peer Reviewed Cancer Research Program (PRCRP) Translational New Investigator Awards
Application Deadline: October 20

Susan G. Komen for the Cure Investigator-Initiated Research (IIR)
Full Application Deadline: November 2

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: November 2

Susan G. Komen for the Cure Promise Grants
Full Application Deadline: December 7

Susan G. Komen for the Cure Postdoctoral Fellowships
Full Application Deadline: January 5, 2011

Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research
Full Application Deadline: January 5, 2011

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

NIH Offers Commercialization Assistance Program to SBIR Phase II Awardees; (NOT-OD-10-125)

Notice of Clarification Regarding Multiple PD/PI Awards and Eligibility for Diversity and Re-Entry Supplement Programs (NOT-OD-10-127)

2011 NIH Regional Seminars on Program Funding and Grants Administration: Phoenix, AZ & Ft. Lauderdale, FL (NOT-OD-10-129)

Scientific Meetings for Creating Interdisciplinary Research Teams in Basic Behavioral and Social Science Research (R13) (RFA-CA-10-017)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.