Case Comprehensive Cancer Center: Weekly Newsletter

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August 23, 2010
CASE CCC IN THE NEWS Fear, Frustration Fuel the Spread of Wrong Information About Cancer Causes Plain Dealer - Aug 17, 2010 ...So it's very natural to look for explanations that seem to make sense," says Dr. Neal Meropol, hematology and oncology division chief of University Hospitals Case Medical Center... Dr. Stanton Gerson, director of UH's Ireland Cancer Center, says that many myths, even though erroneous, gain credence because they have some elements of ... Shaker Heights resident helps bring top medical talent to Cleveland Sun Star Courier (blog) - Aug 17, 2010 Derek Raghavan likes to recruit people for his team in Cleveland. And he's doing a good job of it. As the chairman of the Taussig Cancer Institute at Cleveland Clinic, Raghavan has brought 50-70 new staffers in since he started in 2004... Buried by Advice on Web? Health Libraries Across Cleveland Can Find ... Plain Dealer - Aug 16, 2010 ...the surgical waiting area and the University Hospitals Ireland Cancer Center at Southwest General, to provide instant answers to patient questions. ... Unique Treatment Raises Tricky Bioethical Issues Renal and Urology News - Aug 12, 2010 ... clinicians having to try to make societal discussions and decisions when they're sort of confronted with their own patients," affirmed Robert Dreicer, ... DNA Test May Speed Colon Cancer Diagnosis New York Times - Aug 9, 2010 Exact Sciences' test is based on work by Dr. Vogelstein, Dr. Sanford Markowitz at Case Western Reserve University and Dr. David A. Ahlquist of the Mayo ... Publish or Post? Scientist (blog) - Aug 8, 2010 "I think it's exactly what is needed -- a paradigm shift," said peer-review critic David Kaplan of Case Western Reserve University in Ohio. ... FDA OKs generic version for cancer drug Arimidex Plain Dealer - Aug 3, 2010 The news is "fantastic," said Dr. Paula Silverman, medical director of the Breast Cancer Program at University Hospitals... "You had some people choosing their second choice therapy because of cost issues," says Dr. Halle Moore, an oncologist with the Cleveland Clinic... NEW MEMBERS CORNER Please join us in welcoming the newest members of the Case CCC: Kishore Guda, DVM, PhD Research Instructor, General Medical Sciences- Oncology Cancer Genetics Program Marvin T. Nieman, PhD Assistant Professor, Medicine- Hem/Onc Cancer Cell Signaling Program Eileen Saffran, MSW Senior Clinical Instructor, Family Medicine Cancer Prevention, Control and Population Research Program Matthew K. Summers, PhD Assistant Staff, Cancer Biology Cell Death Regulation Program Sichun Yang, PhD Assistant Professor, Center for Proteomics and Biophysics Cancer Cell Signaling NEWS FROM NIH New Breast Cancer Committee to Establish Federal Research Agenda A newly formed advisory committee will develop and coordinate a strategic federal research agenda on environmental and genetic factors related to breast cancer. The 19-member Interagency Breast Cancer and Environmental Research Coordinating Committee (IBCERCC) was established by the National Institute of Environmental Health Sciences (NIEHS), in collaboration with the National Cancer Institute (NCI), to review all breast cancer research efforts conducted or supported by federal agencies. Click here to view the entire article. ANNOUNCEMENTS Integrative Cancer Biology Course Registration is open for EPBI 473: Integrative Cancer Biology, a course being taught by Dr. Tom Radivoyevitch this fall semester. Nonlinear mathematical representations of cancer relevant processes will be analyzed and used to interpret data where available. Stochastic processes will be introduced for tumor cell numbers and DNA double strand breaks. SEER, A-bomb, omic and cytometry data will be analyzed. MARK YOUR CALENDARS Case CCC Scientific Series: Basic Science of Cancer Focus Group Pilot Projects Come and hear updates on the Basic Science of Cancer Focus Group pilot projects at the next Case CCC Scientific Series, August 30 from 4-7 pm in Wolstein Auditorium (WRB 1413). Cathleen Carlin, PhD and Zhenghe Wang, PhD Cross-Talk Between EGFR and PTPN14 During Integrin-Regulated Cell Adhesion: Role for STAT3 Shigemi Matsuyama, PhD and Alex Almasan, PhD Cell Death Decision Mechanism by the Interaction of Factors Regulating Cell Cycle (CyclinE) and DNA Repair (Ku70) Saba Valadkhan, PhD Characterization of the Anti-Apoptotic Activity of a TGF-B Responsive Non-Coding RNA	EVENTS All events are open to anyone interested in attending August 23 Taussig Cancer Institute Core Curriculum Series Brian Bolwell, MD Professor, Hematology & Medical Oncology CWRU/ Cleveland Clinic Topic:** Bone Marrow Transplantation 12 pm R3-002 Cleveland Clinic August 24 Taussig Cancer Institute Core Curriculum Series Robert Pelley, MD Solid Tumor Oncology Cleveland Clinic Topic: Adjuvant Medical Therapy for Colon Rectal Cancer 12 pm R3-002 Cleveland Clinic Ribonucleotide Reductase Journal Club John Pink, PhD Assistant Professor, Division of General Medical Sciences- Oncology CWRU/ UH Topic: Update on RNR Cell Studies 2 pm SOM W331 August 25 ICC Grand Rounds Hillard Lazarus, MD Professor, Medicine- Hem/Onc CWRU/ UH Topic: Indications and Efficacy of Hematopoietic Stem Cell Transplantation (HSCT) 8 am Lerner Tower B-151 August 26 August 27 Taussig Cancer Institute Grand Rounds will resume September 10 Cancer Center Research in Progress Seminar will resume in September Hematology and Oncology Fellows Alvin Schmaier, MD Professor, Div. of Hem/Onc CWRU/ UH Topic: Thrombotic Disorders 8 am Wearn 137 Case CCC Calendar LRI Calendar UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS Cancer Center Scientific Series August 30 4-7 pm WRB 1-413 Cancer Center Scientific Series November 8 4-7 pm WRB 1-413 ADDITIONAL UPCOMING SEMINARS & EVENTS Clinical Proteomic Technologies for Cancer (CPTC) 2010 Annual Meeting September 8-9 Bethesda North Marriott Hotel & Conference Center, MD Details 2010 caBIG Annual Meeting: Building a Collaborative Biomedical Network September 13-15 Washington, DC Details Oncology Congress October 15-17 San Francisco, CA Details 2010 Cleveland Nanomedicine Summit October 18-19 InterContinental Hotel, Cleveland, OH Clinical and research abstracts will be accepted through October 1 (please note new deadline) Details International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy October 18-19 Purdue University, West Lafayette, IN Details ASCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer October 18-20 Hollywood, FL Call for Abstracts Graft versus Host Disease Conference November 4 Corporate College East, Cleveland, OH Details Active Living Research Annual Conference February 22-24, 2011 San Diego, CA Call for Abstracts Deadline: August 6 Details
CASE CCC SEED FUNDING Request for Proposals: Cancer Stem Cell and Cancer Originating Cell Research Projects The Case Comprehensive Cancer Center will provide seed money to foster collaborations and to promote and increase institution-wide capacity and competitiveness in cancer stem cell and cancer originating cell based research. Four awards of $50,000 will be made to investigators who intend to gather preliminary data to be used in seeking future independently funded programs and support. Case Comprehensive Cancer Center members with a faculty appointment at all levels (eligible to apply for independent nationally competitive research grants) are encouraged to apply. Proposals from both junior and senior investigators are encouraged. Postdoctoral fellows, graduate students and research associates are not eligible to apply for these pilot grants. It is expected that these grants will represent new initiatives, not otherwise funded in new areas of cancer stem cell research. Use of animal models of human disease, primary cancer stem cells and cancer originating cells isolated from human cancers, development of novel cell lines such as iPS of human cancers, and methods development for the isolation of cancer stem cells and cancer originating cell based would be responsive. The NIH ARRA award mechanism will be the source of funds for 2 awards, with matching funds for the additional two awards. Investigators should identify the Cancer Center Scientific Program under which this pilot application is submitted and have a letter from the Program Leader acknowledging the programmatic alignment. Program Leaders can be found on the Cancer Center web site. Deadline: September 10 Details are available on the cancer center website. Request for Proposals: Basic, Clinical, or Translational Human Tissue Based Cancer Research Projects The Case CCC will provide seed money to foster collaborations and to promote and increase institution-wide capacity and competitiveness in basic, clinical or translational human tissue based research. Three awards of $50,000 and three awards at $20,000 apiece will be awarded to investigators who intend to gather preliminary data to be used in seeking future independently funded programs and support. Case CCC members with a faculty appointment at all levels (eligible to apply for independent nationally competitive research grants) are encouraged to apply. Proposals from both junior and senior investigators are encouraged. Postdoctoral fellows, graduate students and research associates are not eligible to apply for these pilot grants. It is expected that these grants will represent collaborative efforts between lab based or quantitative science-based and clinical investigators, likely a clinician who is a member of the disease team of the tissue research in question. Deadline: September 10 Details are available on the cancer center website.	NCI CANCER BULLETIN News Protein Helps Predict Cancer Therapy-induced Heart Damage Bone Drugs Do Not Appear to Increase Esophageal or Gastric Cancer Risk Immune Cells' Anticancer Abilities May Be Hampered by High Lipid Levels microRNA May Regulate Growth of Tumor Blood Vessels Many U.S. and Canadian Oncologists Unprepared to Use Cost-effectiveness Data in Practice In Depth A Cancer Treatment That Sticks Around NCI's Cancer Information Service: Providing Information and Assistance Nationwide Featured Clinical Trial: Cediranib to Treat Alveolar Soft Part Sarcoma The Comprehensive Cancer Center of Wake Forest University Updates Legislative Update Cancer.gov Update Notes
PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
Active Living Research Translating Research to Policy Award Deadline: August 25 Avon Foundation for Women Breast Health Outreach Program Deadline: August 27 Induced Pluripotent Stem Cell Pilot Research Award Application Deadline: extended to August 31 IOTF Cancer Prevention Fellows Application Deadline: September 1 ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure Required LOI Deadline: September 1 Susan G. Komen for the Cure Postdoctoral Fellowships Pre-Application Deadline: September 15 Full Application Deadline: January 5, 2011 Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research Pre-Application Deadline: September 15 Full Application Deadline: January 5, 2011 Leukemia and Lymphoma Society Scholar Awards Required LOI Deadline: September 15 Leukemia and Lymphoma Society Scholars in Clinical Research Awards Required LOI Deadline: September 15 Leukemia and Lymphoma Society Special Fellows Required LOI Deadline: September 15 Leukemia and Lymphoma Society Special Fellows in Clinical Research (SFCR) Awards Required LOI Deadline: September 15 Leukemia and Lymphoma Society Fellows Awards Required LOI Deadline: September 15 Raymond and Beverly Sackler AACR Fellowships for Ileal Carcinoid Tumor Research Deadline: September 15 Caring for Carcinoid Foundation–AACR Grants for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research Deadline: September 15 DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award Pre-Application Deadline: September 15 Application Deadline: September 29	William Lawrence & Blanche Hughes Foundation Deadline: September 16 DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award Application Deadline: September 29 DOD Peer Reviewed Cancer Research Program (PRCRP) Idea Awards Application Deadline: October 20 DOD Peer Reviewed Cancer Research Program (PRCRP) Translational New Investigator Awards Application Deadline: October 20 Susan G. Komen for the Cure Investigator-Initiated Research (IIR) Full Application Deadline: November 2 Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants Full Application Deadline: November 2 Susan G. Komen for the Cure Promise Grants Full Application Deadline: December 7 Susan G. Komen for the Cure Postdoctoral Fellowships Full Application Deadline: January 5, 2011 Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research Full Application Deadline: January 5, 2011 AACR Scholar-in-Training Awards - Special Conferences Application Deadline varies International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships Application Deadline: Open NCI Short-Term Scientist Exchange Program Application Deadline: Open James S. McDonnell Foundation Application Deadline: Open
NIH BULLETIN – Notices and Funding Opportunities Business Innovation Research (SBIR) Program Contract Solicitation (PHS 2011-1) Now Available (NOT-OD-10-124) NIH-RAID Updates on Program Scope and Procedures: Biologics Manufacture, Lead Selection, and Product Development Plans (NOT-RM-10-012) Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) (RFA-GM-11-003) Psychosocial Stress and Behavior: Integration of Behavioral and Physiological Processes (R01) (RFA-HL-11-033) Development of Comprehensive and Conceptually-based Measures of Psychosocial Stress (R21) (RFA-HL-11-034) Basic Mechanisms Influencing Behavioral Maintenance (R01) (RFA-HL-11-035)
Produced by: Gillian Irwin Todd 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216-844-8317 phone 216-844-7832 fax gillian.irwin@case.edu	HELP US HELP YOU! If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu.