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Case Comprehensive Cancer Center Newsletter

August 23, 2010

CASE CCC IN THE NEWS

Fear, Frustration Fuel the Spread of Wrong Information About Cancer Causes
Plain Dealer - Aug 17, 2010
...So it's very natural to look for explanations that seem to make sense," says Dr. Neal Meropol, hematology and oncology division chief of University Hospitals Case Medical Center... Dr. Stanton Gerson, director of UH's Ireland Cancer Center, says that many myths, even though erroneous, gain credence because they have some elements of ...

Shaker Heights resident helps bring top medical talent to Cleveland
Sun Star Courier (blog) - Aug 17, 2010
Derek Raghavan likes to recruit people for his team in Cleveland. And he's doing a good job of it. As the chairman of the Taussig Cancer Institute at Cleveland Clinic, Raghavan has brought 50-70 new staffers in since he started in 2004...

Buried by Advice on Web? Health Libraries Across Cleveland Can Find ...
Plain Dealer - Aug 16, 2010
...the surgical waiting area and the University Hospitals Ireland Cancer Center at Southwest General, to provide instant answers to patient questions. ...

Unique Treatment Raises Tricky Bioethical Issues
Renal and Urology News - Aug 12, 2010
... clinicians having to try to make societal discussions and decisions when they're sort of confronted with their own patients," affirmed Robert Dreicer, ...

DNA Test May Speed Colon Cancer Diagnosis
New York Times - Aug 9, 2010
Exact Sciences' test is based on work by Dr. Vogelstein, Dr. Sanford Markowitz at Case Western Reserve University and Dr. David A. Ahlquist of the Mayo ...

Publish or Post?
Scientist (blog) - Aug 8, 2010
"I think it's exactly what is needed -- a paradigm shift," said peer-review critic David Kaplan of Case Western Reserve University in Ohio. ...

FDA OKs generic version for cancer drug Arimidex
Plain Dealer - Aug 3, 2010
The news is "fantastic," said Dr. Paula Silverman, medical director of the Breast Cancer Program at University Hospitals... "You had some people choosing their second choice therapy because of cost issues," says Dr. Halle Moore, an oncologist with the Cleveland Clinic...


NEW MEMBERS CORNER

Please join us in welcoming the newest members of the Case CCC:

Kishore Guda, DVM, PhD
Research Instructor, General Medical Sciences- Oncology
Cancer Genetics Program

Marvin T. Nieman, PhD
Assistant Professor, Medicine- Hem/Onc
Cancer Cell Signaling Program

Eileen Saffran, MSW
Senior Clinical Instructor, Family Medicine
Cancer Prevention, Control and Population Research Program

Matthew K. Summers, PhD
Assistant Staff, Cancer Biology
Cell Death Regulation Program

Sichun Yang, PhD
Assistant Professor, Center for Proteomics and Biophysics
Cancer Cell Signaling


NEWS FROM NIH

New Breast Cancer Committee to Establish Federal Research Agenda

A newly formed advisory committee will develop and coordinate a strategic federal research agenda on environmental and genetic factors related to breast cancer. The 19-member Interagency Breast Cancer and Environmental Research Coordinating Committee (IBCERCC) was established by the National Institute of Environmental Health Sciences (NIEHS), in collaboration with the National Cancer Institute (NCI), to review all breast cancer research efforts conducted or supported by federal agencies. Click here to view the entire article.


ANNOUNCEMENTS

Integrative Cancer Biology Course

Registration is open for EPBI 473: Integrative Cancer Biology, a course being taught by Dr. Tom Radivoyevitch this fall semester. Nonlinear mathematical representations of cancer relevant processes will be analyzed and used to interpret data where available. Stochastic processes will be introduced for tumor cell numbers and DNA double strand breaks. SEER, A-bomb, omic and cytometry data will be analyzed.


MARK YOUR CALENDARS

Case CCC Scientific Series: Basic Science of Cancer Focus Group Pilot Projects

Come and hear updates on the Basic Science of Cancer Focus Group pilot projects at the next Case CCC Scientific Series, August 30 from 4-7 pm in Wolstein Auditorium (WRB 1413).

Cathleen Carlin, PhD and Zhenghe Wang, PhD
Cross-Talk Between EGFR and PTPN14 During Integrin-Regulated Cell Adhesion: Role for STAT3

Shigemi Matsuyama, PhD and Alex Almasan, PhD
Cell Death Decision Mechanism by the Interaction of Factors Regulating Cell Cycle (CyclinE) and DNA Repair (Ku70)

Saba Valadkhan, PhD
Characterization of the Anti-Apoptotic Activity of a TGF-B Responsive Non-Coding RNA

EVENTS

calendar

**All events are open to anyone interested in attending

August 23

Taussig Cancer Institute Core Curriculum Series
Brian Bolwell, MD
Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: Bone Marrow Transplantation
12 pm R3-002 Cleveland Clinic


August 24

Taussig Cancer Institute Core Curriculum Series
Robert Pelley, MD
Solid Tumor Oncology
Cleveland Clinic
Topic: Adjuvant Medical Therapy for Colon Rectal Cancer
12 pm R3-002 Cleveland Clinic

Ribonucleotide Reductase Journal Club
John Pink, PhD
Assistant Professor, Division of General Medical Sciences- Oncology
CWRU/ UH
Topic: Update on RNR Cell Studies
2 pm SOM W331


August 25

ICC Grand Rounds
Hillard Lazarus, MD
Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Indications and Efficacy of Hematopoietic Stem Cell Transplantation (HSCT)
8 am Lerner Tower B-151


August 26


August 27

Taussig Cancer Institute Grand Rounds will resume September 10

Cancer Center Research in Progress Seminar will resume in September

Hematology and Oncology Fellows
Alvin Schmaier, MD
Professor, Div. of Hem/Onc
CWRU/ UH
Topic: Thrombotic Disorders
8 am Wearn 137

 

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Cancer Center Scientific Series
August 30
4-7 pm WRB 1-413

Cancer Center Scientific Series
November 8
4-7 pm WRB 1-413

ADDITIONAL UPCOMING SEMINARS & EVENTS

Clinical Proteomic Technologies for Cancer (CPTC) 2010 Annual Meeting
September 8-9
Bethesda North Marriott Hotel & Conference Center, MD
Details

2010 caBIG Annual Meeting: Building a Collaborative Biomedical Network
September 13-15
Washington, DC
Details

Oncology Congress
October 15-17
San Francisco, CA
Details

2010 Cleveland Nanomedicine Summit
October 18-19
InterContinental Hotel, Cleveland, OH
Clinical and research abstracts will be accepted through October 1 (please note new deadline)
Details

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN
Details

ASCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer
October 18-20
Hollywood, FL
Call for Abstracts

Graft versus Host Disease Conference
November 4
Corporate College East, Cleveland, OH
Details

Active Living Research Annual Conference
February 22-24, 2011
San Diego, CA
Call for Abstracts Deadline: August 6
Details


CASE CCC SEED FUNDING

Request for Proposals: Cancer Stem Cell and Cancer Originating Cell Research Projects

The Case Comprehensive Cancer Center will provide seed money to foster collaborations and to promote and increase institution-wide capacity and competitiveness in cancer stem cell and cancer originating cell based research. Four awards of $50,000 will be made to investigators who intend to gather preliminary data to be used in seeking future independently funded programs and support. Case Comprehensive Cancer Center members with a faculty appointment at all levels (eligible to apply for independent nationally competitive research grants) are encouraged to apply. Proposals from both junior and senior investigators are encouraged. Postdoctoral fellows, graduate students and research associates are not eligible to apply for these pilot grants.

It is expected that these grants will represent new initiatives, not otherwise funded in new areas of cancer stem cell research. Use of animal models of human disease, primary cancer stem cells and cancer originating cells isolated from human cancers, development of novel cell lines such as iPS of human cancers, and methods development for the isolation of cancer stem cells and cancer originating cell based would be responsive. The NIH ARRA award mechanism will be the source of funds for 2 awards, with matching funds for the additional two awards. Investigators should identify the Cancer Center Scientific Program under which this pilot application is submitted and have a letter from the Program Leader acknowledging the programmatic alignment. Program Leaders can be found on the Cancer Center web site.

Deadline: September 10

Details are available on the cancer center website.

Request for Proposals: Basic, Clinical, or Translational Human Tissue Based Cancer Research Projects

The Case CCC will provide seed money to foster collaborations and to promote and increase institution-wide capacity and competitiveness in basic, clinical or translational human tissue based research.

Three awards of $50,000 and three awards at $20,000 apiece will be awarded to investigators who intend to gather preliminary data to be used in seeking future independently funded programs and support.

Case CCC members with a faculty appointment at all levels (eligible to apply for independent nationally competitive research grants) are encouraged to apply. Proposals from both junior and senior investigators are encouraged. Postdoctoral fellows, graduate students and research associates are not eligible to apply for these pilot grants. It is expected that these grants will represent collaborative efforts between lab based or quantitative science-based and clinical investigators, likely a clinician who is a member of the disease team of the tissue research in question.

Deadline: September 10

Details are available on the cancer center website.



NCI CANCER BULLETIN

News
Protein Helps Predict Cancer Therapy-induced Heart Damage

Bone Drugs Do Not Appear to Increase Esophageal or Gastric Cancer Risk

Immune Cells' Anticancer Abilities May Be Hampered by High Lipid Levels

microRNA May Regulate Growth of Tumor Blood Vessels

Many U.S. and Canadian Oncologists Unprepared to Use Cost-effectiveness Data in Practice

In Depth
A Cancer Treatment That Sticks Around

NCI's Cancer Information Service: Providing Information and Assistance Nationwide

Featured Clinical Trial: Cediranib to Treat Alveolar Soft Part Sarcoma

The Comprehensive Cancer Center of Wake Forest University

Updates
Legislative Update

Cancer.gov Update

Notes

PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Active Living Research Translating Research to Policy Award
Deadline: August 25

Avon Foundation for Women Breast Health Outreach Program
Deadline: August 27

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: extended to August 31

IOTF Cancer Prevention Fellows
Application Deadline: September 1

ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure
Required LOI Deadline: September 1

Susan G. Komen for the Cure Postdoctoral Fellowships
Pre-Application Deadline: September 15
Full Application Deadline: January 5, 2011

Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research
Pre-Application Deadline: September 15
Full Application Deadline: January 5, 2011

Leukemia and Lymphoma Society Scholar Awards
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Scholars in Clinical Research Awards
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Special Fellows
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Special Fellows in Clinical Research (SFCR) Awards
Required LOI Deadline: September 15

Leukemia and Lymphoma Society Fellows Awards
Required LOI Deadline: September 15

Raymond and Beverly Sackler AACR Fellowships for Ileal Carcinoid Tumor Research
Deadline: September 15

Caring for Carcinoid Foundation–AACR Grants for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research
Deadline: September 15

DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award
Pre-Application Deadline: September 15
Application Deadline: September 29


William Lawrence & Blanche Hughes Foundation
Deadline: September 16

DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award
Application Deadline: September 29

DOD Peer Reviewed Cancer Research Program (PRCRP) Idea Awards
Application Deadline: October 20

DOD Peer Reviewed Cancer Research Program (PRCRP) Translational New Investigator Awards
Application Deadline: October 20

Susan G. Komen for the Cure Investigator-Initiated Research (IIR)
Full Application Deadline: November 2

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: November 2

Susan G. Komen for the Cure Promise Grants
Full Application Deadline: December 7

Susan G. Komen for the Cure Postdoctoral Fellowships
Full Application Deadline: January 5, 2011

Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research
Full Application Deadline: January 5, 2011

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Business Innovation Research (SBIR) Program Contract Solicitation (PHS 2011-1) Now Available (NOT-OD-10-124)

NIH-RAID Updates on Program Scope and Procedures: Biologics Manufacture, Lead Selection, and Product Development Plans (NOT-RM-10-012)

Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) (RFA-GM-11-003)

Psychosocial Stress and Behavior: Integration of Behavioral and Physiological Processes (R01) (RFA-HL-11-033)

Development of Comprehensive and Conceptually-based Measures of Psychosocial Stress (R21) (RFA-HL-11-034)

Basic Mechanisms Influencing Behavioral Maintenance (R01) (RFA-HL-11-035)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.