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Case Comprehensive Cancer Center Newsletter

July 19, 2010


Susan G. Komen Awards Case Western Reserve Nearly $500000 to Study Breast ...
Genetic Engineering News - Jul 19, 2010
Cynthia Owusu, MD, associate professor at Case Western Reserve University and geriatric-oncologist at University Hospitals Case Medical Center, the School's ...

Arsenic Shows Promise as Cancer Treatment
AOL Health (blog) - Jul 16, 2010
Dr. Stan Gerson, the director of the University Hospitals Ireland Cancer Center in Cleveland, called the findings "intriguing" but said human trials need to ...

CWRU Researchers Discover Biomarker for Early Warning of Oral Cancer
News-Medical.net - Jul 14, 2010
Annually some 10000 people die from this cancer," said Ge Jin, assistant professor of biological sciences at the dental school. He led the study, ...

Can PSA Screening Decrease Prostate Cancer Mortality?
NCI Cancer Bulletin - Jul 13, 2010
... the state of prostate cancer screening in Sweden was "very different from the situation in the United States right now," explained Dr. Eric Klein, ...

Influence of a Genetic Variation on Breast Cancer Risk is Subject of Five-Year UB Study
UB News Center - Jul 13, 2010
Other mentors include... and Robert Elston, PhD, professor and director of the Division of Genetic and Molecular Epidemiology at Case Western Reserve University in Cleveland, ...

Sunscreen, SPF Advice Worth Repeating
Plain Dealer - Jul 12, 2010
The SPF name change is key, and one that Dr. Kevin Cooper, chairman of the dermatology department at Case Western Reserve University, said ...

Blame's Net Catches Lung Cancer Patients
New York Times - Jul 12, 2010
Dr. Derek Raghavan of the Cleveland Clinic Taussig Cancer Center is answering your questions. Do you have a question about health? ...


Case CCC Scientific Retreat: Poster Session Winners

The Case CCC Scientific Retreat featured 73 scientific poster presentations by Cancer Center students, trainees, postdocs and fellows. Congratulations to the top poster winners:

  • Jason Molitoris (Mentor: Clark Distelhorst)
    Glucocorticoids regulate Bim through the oncogenic microRNA cluster miR-17~92
  • Byeongjun Park (Mentor: Jason Sohn)
    Image Analysis System for Monitoring Treatment Progress
  • Kyung Song (Mentor: David Danielpour)
    Dihydrotestosterone Selectively Reverses Smad3-mediated/TGF-β-induced Responses through Transcriptional Downregulation of Smad3 in Prostate Epithelial Cells
  • Reema Wahdan-Alaswad (Mentor: David Danielpour)
    Insulin-like Growth Factor Suppresses Bone Morphogenetic Protein Signaling through Mammalian Target of Rapamycin Complex 1 and 2
  • Savina Aneja (Mentor: Kevin Cooper)
    The use of local radiation therapy in the management of unilesional and oligolesional primary cutaneous T-cell lymphomas
  • Hui Wang (Mentor: Andrew Rollins)
    A pilot study: Imaging bladder and ureter with optical coherence tomography
  • Ana Ortiz (Mentor: Li Li)
    Insulin Resistance, Central Obesity and Risk of Colorectal Adenomas
Trial Tests GDC-0449 in Adult Glioblastoma

In a new clinical trial open at UH through the Case CCC, Drs. CJ Nock and Andrew Sloan are testing the effect of GDC-0449 in adults with glioblastoma. This drug was also highlighted recently in the NCI Cancer Bulletin for its efficacy in childhood meduloblastoma.

2011 Case CCC Scientific Retreat

Help us schedule the 2011 Case CCC Scientific Retreat. Please click here to take a short two-question survey and let us know the best time of year to hold the retreat. We appreciate your input!



**All events are open to anyone interested in attending

July 19

July 20

Taussig Cancer Institute Grand Rounds
Thomas Budd, MD
Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: Metastatic Breast Cancer
12 pm R3-002 Cleveland Clinic

July 21

Developmental Therapeutics Program Meeting canceled

ICC Grand Rounds
Matthew Cooney, MD
Associate Professor, Medicine- Hem/Onc
Topic: Treatment of Advanced Prostate Cancer
8 am Lerner Tower B-151

July 22

Taussig Cancer Institute Grand Rounds
Halle Moore, MD
Staff, Solid Tumor Oncology
Cleveland Clinic
Topic: Breast Cancer 101, including Adjuvant Therapy
12 pm R3-002 Cleveland Clinic

July 23

Taussig Cancer Institute Grand Rounds will resume September 10

Cancer Center Research in Progress Seminar will resume in September

Hematology and Oncology Special Seminar
E. Scott Kopetz, MD
Assistant Professor, Gastrointestinal Medical Oncology- Cancer Medicine
University of Texas MD Anderson Cancer Center
Topic: Src Inhibition in Metastatic Colorectal Cancer
8 am Wearn 137

For a complete listing of LRI seminars click here.


Cancer Center Scientific Series
August 30
4-7 pm WRB 1-413

Cancer Center Scientific Series
November 8
4-7 pm WRB 1-413


Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI

2010 caBIG Annual Meeting: Building a Collaborative Biomedical Network
September 13-15
Washington, DC

Oncology Congress
October 15-17
San Francisco, CA

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN

ASCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer
October 18-20
Hollywood, FL
Call for Abstracts (Deadline: June 22)


Avon Foundation for Women Breast Health Outreach Program

The Avon Foundation for Women is currently accepting applications for funding through the Avon Breast Health Outreach Program (BHOP). This program provides grants to non-profit organizations to conduct outreach, provide education on breast health and breast cancer screening, and link medically underserved women to health care providers and clinical screening services, as well as work to ensure that women obtain any necessary follow-up care. Small community-based organizations are encouraged to apply.
Deadline: August 27

Alex's Lemonade Stand Foundation

Alex's Lemonade Stand Foundation is accepting applications for the following grants, designed to fill critical voids in current pediatric cancer research:

The 'A' Award is a three year grant designed for young scientists who want to jump-start their career in pediatric oncology research. The ideal candidate has an original project which is not currently being funded. Demonstration of outstanding mentorship and a future commitment to pediatric cancer investigation are critical components of a successful application.
Deadline: August 2

The Nursing Grant Program is designed to encourage nursing research at all levels of practice. In each category the aims of the project must include plans to disseminate and share findings to improve nursing care for children with cancer.
Deadline: August 2

DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award

Applications are now being accepted for the PRCRP Concept Award, which supports the exploration of a highly innovative new concept or untested theory addressing at least one of the FY10 PRCRP Topic Areas. No other Topic Areas will be allowed. The Concept Award supports high-risk studies that have the potential to reveal entirely new avenues for investigation. It is not intended to support a logical progression of an already established research project. Presentation of preliminary data is not allowed. However, a rationale for the work must be provided. Research completed through a Concept Award may generate the data needed to enable the Principal Investigator (PI) to apply for other funding opportunities requiring preliminary data.
Pre-Application Deadline: September 15
Application Deadline: September 29


Graft versus Host Disease Conference

Together with the Case CCC, the Meredith A. Cowden Foundation presents the 2010 National GVHD Symposium to be held at Corporate College East on Thursday, November 4. This unique one-day program will be a two-track conference (one for physicians and one for patients) focusing on cutting edge research and new treatments. Continuing medical education credits will be offered for attending and participating medical providers.

Featured Case CCC presenters include: Drs. Stan Gerson, Ken Cooke, Matt Kalaycio and Jeff Auletta.

2010 Cleveland Nanomedicine Summit

Registration is open for the 2010 Cleveland NanoMedicine Summit, October 18-19 at the InterContinental Hotel. Co-hosted by the Cleveland Clinic and CWRU, this event will continue its incredibly successful format that brings together scientists, clinicians, business professionals, investors, and others to investigate sustainable solutions of multidisciplinary methodologies to further advance the use of nanomedicine in clinical practice. Clinical and research abstracts will be accepted through September 3. Cancer Center members Drs. Vinod Labhasetwar, James Basilion and Maciej Zborowski are on the Organizing Committee.

Third Annual Golf Skills Clinic for Kids Kicking Cancer

The Third Annual Golf Skills Clinic for Kids Kicking Cancer is Monday, August 2. The purpose of this event is to encourage cancer patients of various ages to be active and to recognize the health benefits of physical activity. Activities are planned for a variety of ages, skill levels and physical abilities. Participants who are currently receiving treatment and patients who had a stem cell transplant within the last year, require medical clearance from their oncology nurse or physician. This event is intended for children on and off-treatment, no matter which hospital they may be receiving care from.

This event is free of charge, but advance registration is required. Kids Kicking Cancer is made possible due to the generous support of Iris S. Wolstein, in memory of her husband Bert L. Wolstein


American Cancer Society-Case Comprehensive Cancer Center Pilot Project Funding Opportunity

Pilot funding is available for cancer-related research in basic, clinical, prevention & control, behavioral, health services and epidemiology.

Instructions, frequently asked questions, and applications available at http://cancer.case.edu. For more information, please contact Terri Daso, Cancer Center Administration, 844-7252, tld6@case.edu.

IRG pilot project grants are intended to support independent, self-directed investigators early in their careers (assistant professor or equivalent). Applicants for the pilot project grants should be within 6 years of their first independent research or faculty appointment and eligible to apply for an independent national competitive research grant, but may not currently hold such a grant.

Recipients of IRG pilot project grants must be, at the time of the application, citizens or noncitizen nationals of the United States or its possessions and territories, or must have been lawfully admitted to the United States for permanent residence at the time of application.

Letter of Intent Deadline: July 26
Application Deadline: August 9


Featured Article
Harold Varmus Becomes Fourteenth Director of the National Cancer Institute

Cancer Research Highlights
Adherence Low among Women Taking Adjuvant Hormone Therapy for Early-stage Breast Cancer

Drug that Inhibits DNA-repair Enzyme Shrinks Some Breast and Ovarian Tumors

Colorectal Cancer Screening Rates Rise, Mammography Rates Dip Slightly in the U.S.

Length of Telomeres Linked to Risk for Some Cancers

Study Estimates Cancer Cases Due to Radiation Exposure in the Marshall Islands

In Depth
Spotlight: Synthetic Biology and Cancer: Exploring the Possibilities

A Closer Look: Can PSA Screening Decrease Prostate Cancer Mortality?

Featured Clinical Trial: Targeting HER2 in the Treatment of Ductal Carcinoma In Situ

Community Update: Cancer Survivors Discover the Power of Blogging


Susan G. Komen for the Cure Promise Grants
Pre Application Deadline: extended to August 10
Full Application Deadline: December 1

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: July 30

DOD PRMRP Investigator-Initiated Research Award
Application Deadline: August 5

Mesothelioma Applied Research Foundation
Deadline: August 11

IOTF Cancer Prevention Fellows
Application Deadline: September 1

ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure
Required LOI Deadline: September 1

William Lawrence & Blanche Hughes Foundation
Deadline: September 16

DOD Peer Reviewed Cancer Research Program (PRCRP) Idea Awards
Application Deadline: October 20

DOD Peer Reviewed Cancer Research Program (PRCRP) Translational New Investigator Awards
Application Deadline: October 20

Susan G. Komen for the Cure Investigator-Initiated Research (IIR)
Full Application Deadline: November 2

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: November 2

Susan G. Komen for the Cure Promise Grants
Full Application Deadline: December 1

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

NIH Offers SBIR Niche Assessment Program to Phase I Awardees (NOT-OD-10-112)

Update on Applicability of the Shelf Life Extension Program (SLEP) (NOT-OD-10-114)

Notice of Intent to Publish Funding Opportunity Announcement (FOA) for Support of Cancer Epidemiology Cohorts (NOT-CA-10-029)

Pre-application Meeting for Request for Applications (RFA-CA-10-016) for the Clinical Proteomic Technologies for Cancer Initiative (CPTC): Proteome Characterization Centers (NOT-CA-10-031)

Notice of Intent to Publish a Request for Applications for Tumor Microenvironment Network (TMEN) (NOT-CA-10-032)

Community Clinical Oncology Program Groups (U10) (RFA-CA-10-010)

Community Clinical Oncology Program Research Bases (U10)(RFA-CA-10-011)

Minority-Based Community Clinical Oncology Program Groups (U10) (RFA-CA-10-012)

2011 NIH Directors New Innovator Award Program (DP2) (RFA-RM-10-009)

Informatics, Coordination and Service Center for the Mutant Mouse Regional Resource Centers (U42) (RFA-RR-10-006)

Clinical and Translational Science Coordinating Center (U54) (RFA-RR-10-007)

Amendment: PAR-09-103: Centers for AIDS Research and Developmental Centers for AIDS Research (P30) (NOT-AI-10-033)

Advancing Novel Science in Womens Health Research (ANSWHR) (R21) (PAS-10-226)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.