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Case Comprehensive Cancer Center Newsletter

June 14, 2010

CASE CCC IN THE NEWS

Some Hypertension Drugs Raise Cancer Risks
UPI.com - June 14
Drs. Ilke Sipahi, Daniel Simon and James Fang, who led the study, conducted a meta-analysis of more than 60,000 patients randomly assigned to take either an ARB or a control medication.


ANNOUNCEMENTS

New Appointments to the Cancer Center

G.Q. Zhang, PhD has been appointed as Associate Director for Cancer Informatics of the Case CCC. Dr. Zhang, Professor of Electrical Engineering and Computer Science, has research interests in biomedical informatics and theoretical computer science. In addition to leading the effort to design and develop the MIMI (Multi-Modality, Multi-Resource Information Integration environment), a comprehensive system built to handle tasks such as scheduling, billing, report generation, data uploading, downloading and archiving for shared facilities, he is responsible for the overall development of cancer informatics support.

David Wald, MD, PhD has been appointed Scientific Director of the Hematopoietic Stem Cell Core Facility. He is currently an Assistant Professor in the Department of Pathology at Case Western Reserve and Associate Director of the Histocompatibility and Immunogenetics Laboratory at University Hospitals Case Medical Center.

We welcome new faculty member William Schiemann, PhD, whose appointment as Associate Professor with tenure will be in the Division of General Medical Sciences (Oncology). Dr. Schiemann will co-lead the developing Breast Cancer Program of the Case CCC as well as the TGF-beta Focus Group. Dr. Schiemann's research aims to understand the molecular mechanisms that underlying the "TGF-beta Paradox". This is the most important and unanswered question concerning the pathophysiological functions of this multifunctional cytokine in regulating mammary tumorigenesis, particularly the initiation of metastasis and disease recurrence. His group has made numerous and highly significant contributions toward answering this important question, and in doing so, has established new and important insights into the molecular mechanisms underlying the TGF-beta Paradox and its ability to influence the response of normal and malignant mammary tissues to TGF-beta.

Case CCC Scientific Retreat 2010: Thinking of Cancer as a Disease, Not a Cell Line
photo

Registration is open for the Case CCC Scientific Retreat, July 9-10 at Sawmill Creek Resort and Conference Center in Huron, OH.

This retreat is an opportunity for the Center to identify the areas on which we should focus over the next two years in preparation for our renewal. Also, there will be many opportunities for interaction with your colleagues and fellow program members, including a working lunch and plenary program meetings planning sessions. Everyone is also invited to participate in special interest group discussions at dinner on Friday and breakfast on Saturday.

If you have not already done so, please RSVP for the retreat as soon as possible. Overnight rooms are filling up fast. As a reminder, overnight accommodations will be covered by the Cancer Center, but advance registration is required. We encourage you to stay and enjoy area attractions, such as Cedar Point, Sheldon Marsh Nature Preserve, wineries, the Lake Erie Islands, and Maritime Museums.


NEW FUNDING OPPORTUNITIES

American Cancer Society-Case Comprehensive Cancer Center Pilot Project Funding Opportunity

Pilot funding is available for cancer-related research in basic, clinical, prevention & control, behavioral, health services and epidemiology.

Instructions, frequently asked questions, and applications available at http://cancer.case.edu. For more information, please contact Terri Daso, Cancer Center Administration, 844-7252, tld6@case.edu.

Eligibility:
IRG pilot project grants are intended to support independent, self-directed investigators early in their careers (assistant professor or equivalent). Applicants for the pilot project grants should be within 6 years of their first independent research or faculty appointment and eligible to apply for an independent national competitive research grant, but may not currently hold such a grant.

Recipients of IRG pilot project grants must be, at the time of the application, citizens or noncitizen nationals of the United States or its possessions and territories, or must have been lawfully admitted to the United States for permanent residence at the time of application.

Letter of Intent Deadline: Monday, July 26
Application Deadline: Monday, August 9

EVENTS

calendar

**All events are open to anyone interested in attending

June 14

Physiology & Biophysics Seminar
Albert Lau, PhD
Postdoctoral Scholar, Biochemistry and Molecular Biology
University of Chicago
Topic: Deconstructing Ligand-Binding in Glutamate Receptors
4 pm E-501 SOM


June 15


June 16

Developmental Therapeutics Program meeting canceled

Grand Rounds
Robert Fine, MD
Assistant Professor, Radiation Oncology
CWRU/ UH
Topic: TBA
8 am Lerner B-151

Molecular Cardiology Faculty Seminar Series
Mattias Buck, MA, DPhil
Associate Professor, Physiology and Biophysics
CWRU/ UH
Topic: Plexins as Receptors for Cell Guidance Cues: Understanding the Role of Receptor - Small GTPase Interactions From a Structural and Thermodynamics Perspective
3 pm NC1-202 Cleveland Clinic


June 17


June 18

Hem/Onc Fellows Seminar
Alecia Nero, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: TBA
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Michael Crump, MD
Princess Margaret Hospital
Topic: The Changing Landscape in Relapsed Aggressive Histology Lymphoma
8 am R3-002/003 Cleveland Clinic

Cancer Center Research in Progress Seminar
Jason Molitoris
MSTP Student, Distelhorst Lab, Div. of Hem/Onc
CWRU/ UH
Topic: Glucocorticoids Regulate Bim Through the Oncogenic microRNA Cluster miR-17~92
4 pm WRB 3-136

For a complete listing of LRI seminars click here.

UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

ASCO Review 2010
June 30
InterContinental Hotel
Details

Case CCC Scientific Retreat
July 9-10
The Lodge at Sawmill Creek Resort
Details

Cancer Center Scientific Series
August 30
4-7 pm WRB 1-413

Cancer Center Scientific Series
November 8
4-7 pm WRB 1-413

ADDITIONAL UPCOMING SEMINARS & EVENTS

Business Education Course: "The Business of Regenerative Medicine: From Stem Cells to the Market Place"
July 12-15
Dively Building
Details

Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI
Details

2010 caBIG Annual Meeting: Building a Collaborative Biomedical Network
September 13-15
Washington, DC
Details

Oncology Congress
October 15-17
San Francisco, CA
Details

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN
Details

ASCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer
October 18-20
Hollywood, FL
Call for Abstracts (Deadline: June 22)



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Lustgarten Foundation for Pancreatic Cancer Research
Concept Proposal Deadline: June 14

Children's Cancer Research Fund Clinical Pediatric Research Grants
Application Deadline: June 16

Frontier Community Health Integration Demonstration Program
Deadline: June 22

DOD BCRP Inter-Institutional Training Award
Application Deadline: June 23

DOD BCRP Multi-Team Award
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Application Deadline: June 23

Susan G. Komen for the Cure Investigator-Initiated Research (IIR)
Pre Application Deadline: June 25
Full Application Deadline: November 2

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Pre Application Deadline: June 25
Full Application Deadline: November 2

Ovarian Cancer Research Fund Program Project Development Grants
Application Deadline: June 25

Ovarian Cancer Research Fund Liz Tilberis Scholars Awards
Application Deadline: June 25

Ovarian Cancer Research Fund Ovarian Cancer Research Training Programs of Excellence grant
Application Deadline: June 25

Doctors Cancer Foundation
Deadline: June 30

DOD PRCRP Idea Awards
Pre-application Deadline: July 14
Application Deadline: October 20

DOD PRCRP Translational New Investigator Awards
Pre-application Deadline: July 14
Application Deadline: October 20

CTSC Pilot Funding for Comparative Effectiveness Research (CER) Infrastructure
Deadline: July 15

Administrative Supplements to Advance Special Translational Research Acceleration Projects on Immune Response Modifiers Currently Funded by NCI (NOT-CA-10-025)
Deadline: July 15


Susan G. Komen for the Cure Promise Grants
Pre Application Deadline: July 6
Full Application Deadline: December 1

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: July 30

DOD PRMRP Investigator-Initiated Research Award
Application Deadline: August 5

Mesothelioma Applied Research Foundation
Deadline: August 11

IOTF Cancer Prevention Fellows
Application Deadline: September 1

DOD Peer Reviewed Cancer Research Program (PRCRP) Idea Awards
Application Deadline: October 20

DOD Peer Reviewed Cancer Research Program (PRCRP) Translational New Investigator Awards
Application Deadline: October 20

Susan G. Komen for the Cure Investigator-Initiated Research (IIR)
Full Application Deadline: November 2

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: November 2

Susan G. Komen for the Cure Promise Grants
Full Application Deadline: December 1

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Epigenetic Approaches in Cancer Epidemiology (R01) (PA-10-031)

Epigenetic Approaches in Cancer Epidemiology (R21) (PA-10-032)

My NCBI Tool to Replace eRA Commons for Bibliography Management (NOT-OD-10-103)

Enhancing Peer Review: Advance Notice on Post-Submission Application Materials for NIH Training and Related Applications (NOT-OD-10-104)

Request for Information (RFI): Sleep Disorders Research Plan (NOT-HL-11-107)

Development of Assays for High-Throughput screening for use in Probe and Pre-therapeutic Discovery (R01) (PA-10-213)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.