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Case Comprehensive Cancer Center Newsletter

June 1, 2010

CASE CCC IN THE NEWS

Innovative Chemotherapy Delivery System Comes to Town
Plain Dealer - June 1, 2010
"There were pockets of surgeons who felt very strongly that they were helping patients," said Dr. Neal Meropol, chief of the division of hematology and oncology at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine...

Cleveland State University Professor's Promising Cancer Research Hits an ...
Plain Dealer - May 30, 2010
"I said, 'Dan, try to use this to kill tumors in mice,' " said Kalafatis, recalling his conversation with Dr. Daniel Lindner, who conducts research in the Center for Hematology and Oncology Molecular Therapies at the Cleveland Clinic's Lerner Research Institute...


ANNOUNCEMENTS

Case CCC Scientific Retreat 2010: Thinking of Cancer as a Disease, Not a Cell Line
photo

Registration is open for the Case CCC Scientific Retreat, July 9-10 at Sawmill Creek Resort and Conference Center in Huron, OH.

This retreat is an opportunity for the Center to identify the areas on which we should focus over the next two years in preparation for our renewal. Also, there will be many opportunities for interaction with your colleagues and fellow program members, including a working lunch and plenary program meetings planning sessions. Everyone is also invited to participate in special interest group discussions at dinner on Friday and breakfast on Saturday.

Another exciting addition to this year's agenda is a judged poster session featuring Cancer Center trainees, postdocs and fellows. This session will be a wonderful opportunity to become acquainted with the range of research being conducted in our members' laboratories, and to encourage our postdocs and students.

If you have not already done so, please RSVP for the retreat as soon as possible. Overnight rooms are filling up fast. As a reminder, overnight accommodations will be covered by the Cancer Center, but advance registration is required. We encourage you to stay and enjoy area attractions, such as Cedar Point, Sheldon Marsh Nature Preserve, wineries, the Lake Erie Islands, and Maritime Museums.

Cancer Center ACS IRG Pilot Funds

The RFA for the Cancer Center ACS IRG Pilot Grants to junior faculty investigators will be issued on or before Monday, June 7. These grants of up to $30,000 are awarded to provide seed money to foster cancer research by junior faculty who have no current national grant support of their own and are intended to support preliminary data to be used in seeking future and independently funded programs.

Watch the Cancer Center website for detailed the RFA. Please contact Terri Daso (terri.daso@case.edu) with any questions.

ASCO 2010 Annual Meeting

The Case CCC is pleased to have many members participating in the ASCO Annual Meeting, June 4-8 in Chicago. Click here to view a listing of Cancer Center participation. We encourage members who are attending the meeting to support their colleagues.


NEW FUNDING OPPORTUNITIES

Administrative Supplements to Advance Special Translational Research Acceleration Projects on Immune Response Modifiers Currently Funded by NCI

The NCI is accepting requests for administrative supplements to existing NCI funded grants of the following types: R01, P01, P30, P50, U01, U10, U19, or U54. This initiative is a part of the NCI Special Translational Research Acceleration Project (STRAP) Program. The overall purpose of the STRAP Program is to accelerate integrated research and development, including support of collaborative activities. A STRAP should take advantage of an opportunity to move translational research projects to the point of initiating clinical studies. Unique aspects of the STRAP Program are to support translational projects that would be delayed or are not easily done through the usual NCI funding mechanisms and to provide to these projects NCI resources that have been identified by the scientific community as critical to progress.

This administrative supplement funding opportunity (NOT-CA-10-025) from the STRAP Program is focused on the Immune Response Modifier (IRM) pathway. Any proposed activities to be supported by supplemental funding should be within the overall scope of the active parent NCI grant and interested investigators are encouraged to discuss eligibility with their grant Program Director.

Deadline: July 15

EVENTS

calendar

**All events are open to anyone interested in attending

May 31

Happy Memorial Day!


June 1

Department of Pathology Dissertation Defense
Richard Patrick Weitzel
Laughlin Lab, Div. of Hem/Onc
CWRU/ UH
Topic: microRNA-184 Regulation of NFAT1 in Umbilical Cord Blood CD4+ T-Cells: Implications for Graft Versus Host Disease
12 pm WRB 1-413


June 2

Grand Rounds
Mary Lynn Dell, MD
Associate Professor, Psychiatry
CWRU/ UH
Topic: Sleep and Sleep Medications in Clinical Oncology Practice
8 am Lerner B-151


June 3


June 4

Hem/Onc Fellows Seminar canceled

Taussig Cancer Institute Grand Rounds canceled

Cancer Center Seminar Series/ Blood Club canceled

Cancer Center Research in Progress Seminar
Lachelle Weeks
Graduate Student, Liu Lab, Div. of Hem/Onc
CWRU/ UH
Topic: Expression of the BER Protein, Uracil DNA Glycosylase, is Not Regulated by Cell Cycle Transcription Factor Family, E2F, Following Pemetrexed Treatment
4 pm WRB 3-136

For a complete listing of LRI seminars click here.

UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

ASCO Review 2010
June 30
InterContinental Hotel
Details

Case CCC Scientific Retreat
July 9-10
The Lodge at Sawmill Creek Resort
Details

Cancer Center Scientific Series
August 30
4-7 pm WRB 1-413

Cancer Center Scientific Series
November 8
4-7 pm WRB 1-413

ADDITIONAL UPCOMING SEMINARS & EVENTS

Business Education Course: "The Business of Regenerative Medicine: From Stem Cells to the Market Place"
July 12-15
Dively Building
Details

Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI
Details

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN
Details

ASCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer
October 18-20
Hollywood, FL
Call for Abstracts (Deadline: June 22)

Peer Reviewed Cancer Research Program (PRCRP)

The Fiscal Year 2010 (FY10) Defense Appropriation Act provides for $15 million (M) to the Department of Defense (DOD) Peer Reviewed Cancer Research Program (PRCRP) to research cancers not addressed in the breast, prostate, and ovarian cancer research programs currently executed by the DOD U. S. Army Medical Research and Materiel Command (USAMRMC).

Idea Awards support the exploration of ideas that are still in the early stages of development yet have the potential to yield high-impact results and open new avenues of investigation in the relevant topic areas. Proposals must not address breast, prostate, lung, or ovarian cancer research. Preliminary data is not required. Clinical Trials will not be supported. The maximum period of performance is 3 years. The maximum allowable direct cost amount for the entire period of performance is $375,000. In addition to direct costs, indirect costs may be proposed in accordance with the institution's negotiated rate agreement. Collaborative Option: Up to three investigators may collaborate on a single application, each of whom will be recognized as a principal investigator (PI) and receive a separate award. For multiple PIs, the combined total funding for all PIs from the entire period of performance may not exceed $750,000 in direct costs.
Pre-application Deadline: July 14
Application Deadline: October 20

Translational New Investigator Awards support the development of translational research collaborations between an independent new investigator and a mentor to address at least one of the FY10 PRCRP Topic Areas in a manner relevant to military beneficiaries. Either the new investigator or the mentor must be a clinician. Proposal must not address breast, prostate, lung, or ovarian cancer research. Preliminary data are not required. Clinical trials will not be supported. Funding: The maximum period of performance is 3 years. The maximum allowable direct cost amount for the entire period of performance is $300,000. In addition to direct costs, indirect costs may be proposed in accordance with the institution's negotiated rate agreement.
Pre-application Deadline: July 14
Application Deadline: October 20

CTSC Pilot Funding for Comparative Effectiveness Research (CER) Infrastructure

The CTSC announces a new pilot competition for Comparative Effectiveness Research (CER) Infrastructure. Three pilots will be awarded at $50,000 each. The funding period is August 1, 2010 thru February 28, 2011.
Deadline: July 15

Lustgarten Foundation

The Lustgarten Foundation invites collaborative or individual applications proposing innovative approaches to target K-ras. Pancreatic cancers are one of the most lethal of all cancers and studies have found that up to 95% contain K-ras mutations. Therefore, the Foundation is prepared to allocate a significant portion of its multi-million dollar budget to a K-ras program.
Concept Proposal Deadline: June 14, 2010

MARK YOUR CALENDARS

Oncology Congress

Registration is now open for the Sixth Annual Oncology Congress, October 15-17 in San Francisco, CA.

This conference provides US-based, practicing oncologists, nurses and pharmacists with the latest clinical data and technology-driven innovations that directly enhance clinical practice and patient care.

At the conclusion of the Oncology Congress, participants will be better able to:

  • Define multidisciplinary treatment strategies.
  • Develop optimal treatment plan by therapeutic area taking into consideration stage of disease, patient age, co-morbidities, and treatment history.
  • Identify how to apply the use of biomarkers as a therapeutic option with a focus on breast, colorectal, prostate, and lung cancer as well as leukemia and lymphoma.
  • Analyze mechanism of action to assess appropriate use of current and emerging molecularly targeted agents.
  • Formulate strategies for preventing, monitoring, and treating chemotherapy-induced side effects such as anemia, emesis, thrombosis, neutropenia, oral mucositis, and peripheral neuropathy.
  • Evaluate available and appropriate interventions and treatments designed to improve outcomes for adolescents and young adults with cancer.
  • Assess and apply new treatment approaches for patients with orphan cancers such as esophageal, kidney, liver, multiple myeloma, pancreatic, MDS, ovarian.

RACE FOR THE PLACE

Join Our Team

Come walk/run with us at the Race for the Place, an event to support the Gathering Place on Sunday, June 6 at Beachwood Place Mall. Registration opens at 7:30 am; race begins with the Survivor Ceremony at 9 am. Email gillian.irwin@case.edu for more information.


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 1

BCRF-AACR Grants for Translational Breast Cancer Research
LOI Deadline: June 7
Application Deadline: August 23

DOD PCRP Idea Development Awards
Application Deadline: June 9

DOD PCRP Synergistic Idea Development Awards
Application Deadline: June 9

DOD OCRP Translational Pilot Award
Application Deadline: June 10

Children's Cancer Research Fund Clinical Pediatric Research Grants
Application Deadline: June 16

Frontier Community Health Integration Demonstration Program
Deadline: June 22

DOD BCRP Inter-Institutional Training Award
Application Deadline: June 23

DOD BCRP Multi-Team Award
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Application Deadline: June 23

Susan G. Komen for the Cure Investigator-Initiated Research (IIR)
Pre Application Deadline: June 25
Full Application Deadline: November 2

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Pre Application Deadline: June 25
Full Application Deadline: November 2

Ovarian Cancer Research Fund Program Project Development Grants
Application Deadline: June 25

Ovarian Cancer Research Fund Liz Tilberis Scholars Awards
Application Deadline: June 25


Ovarian Cancer Research Fund Ovarian Cancer Research Training Programs of Excellence grant
Application Deadline: June 25

Doctors Cancer Foundation
Deadline: June 30

Susan G. Komen for the Cure Promise Grants
Pre Application Deadline: July 15
Full Application Deadline: December 1

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: July 30

DOD PRMRP Investigator-Initiated Research Award
Application Deadline: August 5

IOTF Cancer Prevention Fellows
Application Deadline: September 1

Susan G. Komen for the Cure Investigator-Initiated Research (IIR)
Full Application Deadline: November 2

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: November 2

Susan G. Komen for the Cure Promise Grants
Pre Application Deadline: July 15
Full Application Deadline: December 1

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open


NIH BULLETIN – Notices and Funding Opportunities

Request for Information (RFI) on the NIH Plan to Develop the Genetic Testing Registry

Administrative Supplements to Advance Special Translational Research Acceleration Projects on Immune Response Modifiers Currently Funded by the National Cancer Institute (NCI) (NOT-CA-10-025)

Biology of Manual Therapies (R01) (PA-10-209)

Biology of Manual Therapies (R21) (PA-10-210)

The Role of Microbial Metabolites in Cancer Prevention and Etiology (U01) (PAR-10-208)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.