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Case Comprehensive Cancer Center Newsletter

May 17, 2010


The annual scientific retreat of the Cancer Center will be July 9-10 at Sawmill Creek Resort and Conference Center, a lovely setting in Huron, Ohio where the retreat was held two years ago. The resort offers numerous outdoor activities including golf, swimming, volleyball, tennis, basketball, and walking trails. There is also an indoor pool, fitness center and game room on the grounds.

The overall theme for this year's retreat will be "Thinking of Cancer as a Disease, Not a Cell Line". We are currently midway through our cycle, and this is an opportunity for us to identify the areas on which the Cancer Center should focus over the next two years. The program begins on Friday with presentations by some of the new cancer research faculty recruited over the last year, and the afternoon topics will review research highlights of four of the Scientific Programs: Cancer Imaging, Cancer Cell Signaling, Cell Death Regulation, and Cancer Prevention, Control and Population Research. A discussion on investigator experiences and lessons learned in initiating tissue based research will be the final formal presentation of the day.

Saturday's program will include a panel of study section members who have participated in recent NIH reviews and will offer their experiences with the new page limitations and scoring system. Following that session, the presentation topics will include a session on developmental therapeutics, focusing specifically on mechanisms to therapeutics, followed by a session on the reciprocal relationship between cancer cohorts and gene discovery.

Opportunities for interaction with your colleagues and fellow program members include a working lunch and program meeting, which will include some scientific presentations and discussion and strategic planning. This year we plan to introduce the concept of having special interest group discussions at Friday's dinner and Saturday's breakfast; this will be an opportunity for members to join a focused scientific discussion if they wish. We encourage members to recommend topics.

Another addition to this year's agenda that we are especially excited about is our decision to invite Cancer Center trainees, postdocs and fellows to present posters. Awards will be given to the top five posters. This session will be a wonderful opportunity to become acquainted with the range of research being conducted in our members' laboratories and to encourage our postdocs and students.

The program will end at 12:30 pm on Saturday, and we encourage you to stay and enjoy area attractions, such as Cedar Point, Sheldon Marsh Nature Preserve, wineries, the Lake Erie Islands, and Maritime Museums.

Thank you for your continued commitment to the Cancer Center. I look forward to seeing you on July 9-10.

Stan Gerson, MD
Director, Case Comprehensive Cancer Center

CALL FOR ABSTRACTS– Cancer–Related Research

The Case CCC Retreat will feature a poster presentation session the evening of Friday, July 9. All graduate students, postdocs and fellows conducting cancer research are invited to submit abstracts. The Retreat Program Committee will review abstracts based on the relationship to cancer, novelty, significance of findings, and clarity. Monetary prizes will be awarded. More information is available on the Call for Abstracts page.

Deadline to submit abstracts to cancer@case.edu is Friday, May 21 at 5 pm.

NIH BUDGET NEWS– FY2011 Senate Labor/HHS Appropriations Hearing Summary

NIH Director Francis Collins, MD, PhD testified before the Senate Labor, Health and Human Services, Education and Related Agencies Appropriations Subcommittee on Wednesday, May 5 at a hearing to examine the NIH FY2011 budget.

Senator Arlen Specter urged the scientific community to increase funding for biomedical research. A variety of issues were covered during the hearing, including cancer clinical trials, the NIH research portfolio balance, stem cell research, and Cures Acceleration Network (CAN), and concerns over the FY2011 funding situation.

Click here to view a complete summary of the hearing.

FUNDING OPPORTUNITY– Susan G. Komen for the Cure

Susan G. Komen for the Cure is accepting applications for the following opportunities:

Investigator-Initiated Research (IIR): provide up to $600,000 over three years to stimulate exploration of new ideas and novel approaches in breast cancer research and clinical practice that will lead to reductions in breast cancer incidence and mortality within the next decade. Komen is introducing a new approach to its IIR RFA in an effort to align supported research projects with Komen's annual strategic objectives and to provide consistency for the research community. For the next few years, the IIR RFA will focus on four standing topic areas—prevention/early detection; novel therapeutics and resistance; the biology of breast cancer; and disparities—within which very specific research issues will be identified for that year's RFA. This year's research areas are as follows: Prevention/Early Detection- Molecular Predictors of High Risk and Early Disease; Novel Therapeutics and Resistance-Targeted Therapies for Hormone Receptor Positive Breast Cancer with Resistance to Endocrine Therapies; Biology of Breast Cancer- 1) Biological Underpinnings and Therapeutic Implications of Micrometastases and 2) Epigenetic Alterations; and all issues relevant to Disparities in Breast Cancer Outcomes.
Pre Application Deadline: June 4
Full Application Deadline: September 30

Career Catalyst Research (CCR) Grants: provide unique opportunities for scientists in the early stages of their career to achieve research independence with an independent award of up to $450,000 over three years. CCR investigators lead a research project addressing an important question in breast cancer research and complete a self-defined career development plan with support from a mentor committee. This year's annual research focus areas are: Biology and Translation, and Disparities in Breast Cancer Outcomes.
Pre Application Deadline: June 4
Full Application Deadline: September 30

Promise Grants: seek to support integrated programs of collaborative and cross-disciplinary research projects leading to the aggressive translation of scientific discoveries into interventions and strategies that have the greatest potential to significantly reduce breast cancer incidence and mortality.
Pre Application Deadline: July 15
Full Application Deadline: December 1


**All events are open to anyone interested in attending

May 17

Physiology & Biophysics Seminar
Xin Qi, PhD
Postdoctoral Fellow, Chemical and Systems Biology
Stanford University
Topic: Delta Protein Kinase C: A Target of Neurological Disorder
4 pm SOM E501

May 18

Department of Medicine 11th Annual Jack H. Berman Lecture
Charles A. Dinarello, MD
Professor, Medicine
University Of Colorado
Topic: IL-1beta and the Spectrum of Inflammatory Diseases
12 pm Kulas Auditorium, Lakeside 5th floor

May 19

Grand Rounds
James Swain, PhD
Assistant Professor, Nutrition
Topic: Iron Supplementation and Intestinal Tumorigenesis
8 am Lerner B-151

Showcase Seminar
Jeremy Rich, MD
Chairman and Professor, Stem Cell Biology & Regenerative Medicine
CWRU/ Cleveland Clinic
Topic: Transformers: How Stem Cells Are More Than Meets the Eye
4:30 pm NE1-205 Cleveland Clinic

Developmental Therapeutics Program Meeting
5 pm WRB 2-136
Refreshments will be served

May 20

Neurosciences Seminar
Julie Kauer, PhD
Professor, Molecular Pharmacology, Physiology & Biotechnology
Brown University
Topic: TRPV1: Hot Channels Required for Hippocampal LTD
12:10 pm BRB 105

Aging-Cancer-Energetics Seminar
Polly Mazanec, PhD, MSN
Assistant Professor, Nursing
Topic: Distance Caregiving a Parent with Advanced Cancer
4 pm BRB 732

Biacore Fundamentals Workshop
Eric Roush, PhD
Senior Application Scientist
GE Healthcare Life Sciences
Topic: Biacore Basics Lecture
3-6 pm SOM E501

May 21

Cancer Center Seminar Series/ Blood Club canceled

Hem/Onc Fellows Seminar
Anita Schwandt, MD
Fellow, Div. of Hem/Onc
Topic: TBA
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Gregory Videtic, MD
Associate Professor, Radiation Oncology
Cleveland Clinic
Topic: The Role of Stereotactic Body Radiotherapy in the Management of Non-Small Cell Lung Cancer: An Emerging Standard for the Medically Inoperable Patient
8 am R3/002-003 Cleveland Clinic

Biacore Fundamentals Workshop
Eric Roush, PhD
Senior Application Scientist
GE Healthcare Life Sciences
Topic: Hands-on Training with the T-100
9 am-12 pm SOM E501

Cancer Center Research in Progress Seminar
Topic: TBA
4 pm WRB 3136


For a complete listing of LRI seminars click here.


ASCO Review 2010
June 30
InterContinental Hotel

Case CCC Scientific Retreat
July 9-10
The Lodge at Sawmill Creek Resort


Business Education Course: "The Business of Regenerative Medicine: From Stem Cells to the Market Place"
July 12-15
Dively Building

Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN

FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (tracy.rehl@case.edu).

Job Description


We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!


Come walk/run with us at the Race for the Place, an event to support the Gathering Place on Sunday, June 6 at Beachwood Place Mall. Registration opens at 7:30 am; race begins with the Survivor Ceremony at 9 am. Email gillian.irwin@case.edu for more information.


The Cancer Center is attempting to track members who are part of the formal program or presenting a poster at the ASCO Annual Meeting, June 4-8 in Chicago. Please send information to gillian.irwin@case.edu.


DOD NFRP Clinical Trial Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Focused Research Award
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Application Deadline: May 20

DOD NFRP New Investigator Award
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Application Deadline: May 20

DOD BCRP Concept Award
Pre-Application Deadline: May 12
Application Deadline: May 26

DOD PCRP Health Disparity Research Award
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Application Deadline: May 26

IOTF Oncology Product Research/Review Fellows
Application Deadline: May 30

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 1

DOD PCRP Idea Development Awards
Application Deadline: June 9

DOD PCRP Synergistic Idea Development Awards
Application Deadline: June 9

DOD OCRP Translational Pilot Award
Application Deadline: June 10

Children's Cancer Research Fund Clinical Pediatric Research Grants
Application Deadline: June 16

DOD BCRP Inter-Institutional Training Award
Application Deadline: June 23

DOD BCRP Multi-Team Award
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Application Deadline: June 23

Ovarian Cancer Research Fund Program Project Development Grants
Application Deadline: June 25

Ovarian Cancer Research Fund Liz Tilberis Scholars Awards
Application Deadline: June 25

Ovarian Cancer Research Fund Ovarian Cancer Research Training Programs of Excellence grant
Application Deadline: June 25

Doctors Cancer Foundation
Deadline: June 30

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: July 30

DOD PRMRP Investigator-Initiated Research Award
Application Deadline: August 5

IOTF Cancer Prevention Fellows
Application Deadline: September 1

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Notice of Intent to Publish Request for Applications for the Clinical Proteomic Technologies for Cancer Initiative (CPTC): Proteome Characterization Centers (NOT-CA-10-027)

Notice of Availability of Administrative Supplements for the U.S.-JAPAN Brain Research Cooperative Program U.S. Component (NOT-NS-10-014)

Centers of Biomedical Research Excellence (COBRE) Phase III: Transitional Centers [P30] (PAR-10-196)

Findings of Misconduct in Science (NOT-OD-10-095)

12th Annual NIH SBIR/STTR Conference to be held June 2 & 3, 2010, Raleigh, NC (NOT-OD-10-096)

Budgeting for Genomic Arrays for NIH Grants, Cooperative Agreements and Contracts (NOT-OD-10-097)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.