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Case Comprehensive Cancer Center Newsletter

May 3, 2010

CASE CCC IN THE NEWS

Study: Options for Post-Menopausal Breast Cancer Prevention
WKYC-TV - Apr 27, 2010
"We encourage all women to discuss their individual risk factors with their doctor and to consider treatment if eligible," said said Rosemary Leeming, surgical oncologist and director of the UH Ireland Cancer Center site for this study. ...

Prostate Cancer Treatment Approved by FDA
Plain Dealer - April 29, 2010
"I'm not surprised by the length of time at all," Dr. Stanton Gerson, a member of that FDA advisory panel and director of the Ireland Cancer Center at ...

FDA OKs Provenge for Prostate Cancer Therapy
WebMD - Apr 29, 2010
It will "re-energize" work in a field that is littered with disappointing failures, says Robert Dreicer, MD, chairman of Cleveland Clinic's department of ...

FDA Approves Immune-boosting Therapy for Prostate Cancer
Los Angeles Times - April 30, 2010
... agreed to," said Dr. Stanton Gerson, director of the University Hospitals Ireland Cancer Center in Cleveland and a member of the FDA advisory committee. ...

Oncology Times Welcomes New Advisory Editors: Mikkael Sekeres, MD, MS Ramaswamy Govindan, MD...
Newswise (press release) - May 3, 2010
Oncology Times has added two Clinical Advisory Editors to its editorial team: Mikkael A. Sekeres, MD, MS, as Clinical Advisory Editor for Hematology/Oncology ...

Letters: How to Fix the Cancer Trials Program
New York Times - May 2, 2010
Dr. Neal Meropol wrote the following published "Letter to the Editor" in response to the April 24 New York Times article, Faltering Cancer Trials:

To the Editor:

As a clinical investigator for more than 20 years, I have personally experienced the successes and frustrations associated with the publicly financed clinical trials system.

It is well recognized that clinical trials are critical to improving cancer care. But an important point not mentioned in your editorial is that cancer patient participation in clinical trials is abysmally low. In fact, only a small percentage of all adult cancer patients takes part in clinical trials. This low participation rate comes at a time when scientific discoveries and technologies are providing the opportunity to test an unprecedented number of promising new treatments.

There are many reasons for this low participation rate. As you note, operational inefficiencies in the nation's clinical trials infrastructure and inadequate financial support for clinical investigation are certainly partly to blame. But as a society we have done a poor job emphasizing the importance of clinical research as an integral component of high-quality cancer care.

Taking part in a clinical trial offers the opportunity to advance cancer treatment, while gaining access to the latest innovations under the careful watch of an infrastructure designed to ensure patient safety. It is time that we take note of the marketing skills that have contributed to the adoption of so many unhealthy behaviors (smoking, fast food), and apply them to a more healthful goal: widespread recognition that cancer clinical trials represent the best treatments we have to offer.

Neal J. Meropol
Cleveland, April 27, 2010

The writer is chief, Division of Hematology and Oncology, University Hospitals Ireland Cancer Center at Case Western Reserve University.

More information on NCI clinical trials is available in the Institute of Medicine April 2010 report, A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program.


KUDOS

Dr. Joseph Baar has been nominated as a finalist for the Crain's Business Cleveland 2010 Health Care Hero in the Advancements in Health Care category. The winner will be announced at a May 6 luncheon ceremony.


NIH NEWS– ARRA Awards Are Eligible for No Cost Extensions

Francis Collins, Director of the NIH, announced that ARRA Awards are eligible for no cost extensions. The NIH treats ARRA awards under the same terms as other awards under the NIH Grants Policy Statement including the authority to extend the final budget period of a previously approved project period for up to 12 months without additional funds, i.e., provide a twelve month no cost extension, without prior approval. However, requests for a second no cost extension will likely not receive approval as the intent of the ARRA funding is to provide a near term stimulus to the economy.


AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO) ANNUAL MEETING PRESENTATIONS & POSTERS

The Cancer Center is attempting to track members who are part of the formal program or presenting a poster at the ASCO Annual Meeting, June 4-8 in Chicago. Please send information to gillian.irwin@case.edu.


RACE FOR THE PLACE– Join Our Team

Come walk/run with us at the Race for the Place, an event to support the Gathering Place on Sunday, June 6 at Beachwood Place Mall. Registration opens at 7:30 am; race begins with the Survivor Ceremony at 9 am. Email gillian.irwin@case.edu for more information.


CALL FOR ABSTRACTS– Cancer–Related Research

The Case CCC Retreat will feature a poster presentation session the evening of July 9. All graduate students, postdocs and fellows conducting cancer research are invited to submit abstracts. The Retreat Program Committee will review abstracts based on the relationship to cancer, novelty, significance of findings, and clarity. Monetary prizes will be awarded. More information is available on the Call for Abstracts page.

Deadline to submit abstracts to cancer@case.edu is Friday, May 21 at 5 pm.

EVENTS

**All events are open to anyone interested in attending

May 3

Physiology & Biophysics Seminar
Arthur Palmer, PhD
Professor and Acting Chair, Biochemistry and Molecular Physics
Columbia University
Topic: Conformational Dynamics and Function in Ribonuclease H and Cadherin 8
4 pm SOM E501


May 4


May 5

Grand Rounds
Mary Lynn Dell, MD
Associate Professor, Psychiatry
CWRU/ UH
Topic: Sleep Medications
8 am Lerner B-151

Genetics Seminar
Tomasz Kordula, PhD
Associate Professor, Biochemistry & Molecular Biology
Virginia Commonwealth University
Topic: From Astrocyte Differentiation to Glioma Invasion
11 am BRB 105

Center for Translational Neuroscience
Richard Zigmond, PhD
Professor, Neurosciences
CWRU
Topic: Neurotrophins and Cytokines: Signals in the Neuronal Response to Injury
11 am SOM E501


May 6

Aging-Cancer-Energetics Seminar
Cynthia Owusu, MD
Assistant Professor, Medicine-Hematology/Oncology
CWRU/ UH
Topic: Functional Decline in Older Patients with Breast Cancer
4 pm BRB 732


May 7

Case CCC Conference: Women's Cancer: Screening and Prevention in 2010
7:30 am Hilton Cleveland East

Hem/Onc Fellows Seminar
Scott Sommers, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: Erythropoesis Stimulating Agents in Malignancy: The Good, the Bad and the Confusing
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Michael Ewer, MD
Professor, Division of Internal Medicine
University of Texas/ M.D. Anderson Cancer Center
Topic: Cardiotoxicity Related to Anti-Cancer Treatment: Not Just the Same Old Heart Failure
8 am R3/002-003 Cleveland Clinic

Cell Biology Seminar Series
Jeffrey Rosen, PhD
Professor, Cell Biology
Baylor College of Medicine
Topic: Therapeutic Targeting of Breast Cancer Tumor Initiating Cells
10 am NC1-202 Cleveland Clinic

Cancer Center Research in Progress Seminar
Kalpana Gupta, PhD
Postdoc, Wald Lab
CWRU
Topic: Discovery of a Novel Approach for AML Differentiation Therapy
4 pm WRB 3136

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Case CCC Scientific Retreat
July 9-10
The Lodge at Sawmill Creek Resort


ADDITIONAL UPCOMING SEMINARS & EVENTS

Midwest Blood Club Symposium
May 6-7
Indiana University School of Medicine
Details

Business Education Course: "The Business of Regenerative Medicine: From Stem Cells to the Market Place"
July 12-15
Dively Building
Details

Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI
Details

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN
Details


FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (tracy.rehl@case.edu).

Job Description



CASE CCC ON FACEBOOK AND LINKEDIN– Join Us!

We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!


PREVIOUSLY ANNOUNCED OPPORTUNITIES

DOD BCRP Idea Award
Application Deadline: May 5

DOD PCRP Health Disparity Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD BCRP Concept Award
Pre-Application Deadline: May 12
Application Deadline: May 26

DOD PRMRP Clinical Trial Award
Application Deadline: May 13

DOD PRMRP Technology/Therapeutic Development Awards
Application Deadline: May 13

DOD NFRP Clinical Trial Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Focused Research Award
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Application Deadline: May 20

DOD NFRP New Investigator Award
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Application Deadline: May 20

DOD BCRP Concept Award
Pre-Application Deadline: May 12
Application Deadline: May 26

DOD PCRP Health Disparity Research Award
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Application Deadline: May 26


DOD PCRP Prostate Cancer Training Award
Application Deadline: May 26

IOTF Oncology Product Research/Review Fellows
Application Deadline: May 30

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 1

DOD PCRP Idea Development Awards
Application Deadline: June 9

DOD PCRP Synergistic Idea Development Awards
Application Deadline: June 9

DOD OCRP Translational Pilot Award
Application Deadline: June 10

Children's Cancer Research Fund Clinical Pediatric Research Grants
Application Deadline: June 16

DOD BCRP Inter-Institutional Training Award
Application Deadline: June 23

DOD BCRP Multi-Team Award
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Application Deadline: June 23

Ovarian Cancer Research Fund Program Project Development Grants:
Application Deadline: June 25

Ovarian Cancer Research Fund Liz Tilberis Scholars awards
Application Deadline: June 25

Ovarian Cancer Research Fund Ovarian Cancer Research Training Programs of Excellence grant
Application Deadline: June 25

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: July 30

DOD PRMRP Investigator-Initiated Research Award
Application Deadline: August 5

IOTF Cancer Prevention Fellows
Application Deadline: September 1

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Extension of Expiration date for PA-07-277, PA-06-367, and PA-06-368: Research on Ethical Issues in Human Subjects Research (NOT-OD-10-086)

Final Opportunity to Attend a 2010 NIH Regional Seminar on Program Funding & Grants Administration: Register Now for Portland, OR (June 24-25, 2010) (NOT-OD-10-092)

Assay Development for High Throughput Molecular Screening (R21) (PAR-10-182)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.