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Case Comprehensive Cancer Center Newsletter

April 26, 2010

MESSAGE FROM THE DIRECTOR

Neal Meropol, MD: Appointment as Chief, Division of Hematology-Oncology, Department of Medicine, University Hospitals Case Medical Center

Please join me in congratulating Dr. Neal Meropol, who will remain as Associate Director for Clinical Research in the Case Comprehensive Cancer Center, in his new position as Chief, Division of Hematology-Oncology, Department of Medicine, University Hospitals Case Medical Center. This joint activity will enhance Neal's ability to coordinate clinical trials and clinical-translational research within the Division and the Cancer Center. In many ways, joining these activities together complements Neal's skills managing people and projects and his advocacy for high quality clinical trials research.

Please also see the official announcement of Neal's appointment from Department of Medicine Chairman, Dr. Richard Walsh.

Stan Gerson, MD
Director, Case CCC


CASE CCC IN THE NEWS

Cleveland Clinic Gets $2M to Expand Cancer Research Facilities
MedCity News - Apr 22, 2010
... from the lab to the bedside to aid in the diagnosis and treatment of patients," said Dr. Derek Raghavan, chairman of the Taussig Cancer Institute. ...


NCI ARRA NEWS– Stimulus Funding Expands Opportunities to Enhance Cancer Research and Care at Community Hospitals

The National Cancer Institute (NCI), part of the National Institutes of Health (NIH), is using $80 million from the American Recovery and Reinvestment Act (ARRA) to expand research benefiting patients at the 16 member hospitals of the NCI Community Cancer Centers Program (NCCCP) and to add 14 new hospitals to the current network.

The expansion uses approximately $40 million of ARRA funds to support additional research opportunities within the original network of 16 NCCCP sites and another $40 million of ARRA funds to expand the network to include 14 new community cancer centers, for a total of 30 sites in 22 states.


RACE FOR THE PLACE– Join Our Team

Come walk/run with us at the Race for the Place, an event to support the Gathering Place on Sunday, June 6 at Beachwood Place Mall. Registration opens at 7:30 am; race begins with the Survivor Ceremony at 9 am. Email gillian.irwin@case.edu for more information.


NCI CANCER BULLETIN

Featured Article
Long-term Follow-up Confirms Breast Cancer Risk Reduction with Raloxifene

Cancer Research Highlights
MicroRNAs Linked to Trastuzumab Resistance, Brain Metastases

Diabetes Drug Metformin Prevents Lung Tumors in Mice

Cancer Risk Tools May Need Regular Recalibration

Profiling Airway Cells May Identify Smokers at Highest Risk of Cancer

Peptide Helps Chemotherapy Penetrate Deep into Tumors

Director's Update
An Unexpected Opportunity, a Welcome Honor


CALL FOR ABSTRACTS– Cancer–Related Research

The Case CCC Retreat will feature a poster presentation session the evening of July 9. All graduate students, postdocs and fellows conducting cancer research are invited to submit abstracts. The Retreat Program Committee will review abstracts based on the relationship to cancer, novelty, significance of findings, and clarity. Monetary prizes will be awarded. More information is available on the Call for Abstracts page.

Deadline to submit abstracts to cancer@case.edu is Friday, May 21 at 5 pm.


KUDOS

Horst von Recum, PhD was recently awarded a National Science Foundation Career Grant: Research and Educational Program in Affinity-Based Drug Delivery.


CALL FOR APPLICATIONS– Cancer Research Training Award

The NCI is pleased to request applications from qualified candidates for a Cancer Research Training Award (CRTA). The CRTA provides an outstanding opportunity for an individual with a strong interest in understanding how cancer care and cancer control activities influence patterns of care and trends in cancer, specifically in the fields of cancer screening and the use of biomarkers in population-based research. The CRTA appointment is a one- or two-year position with the Applied Research Program, Division of Cancer Control and Population Sciences of the NCI.

This position provides an exciting and unique opportunity to work with leaders in the fields of diet, weight, and physical activity related to cancer and other chronic diseases. The position will allow contact with a large number of scientists representing disciplines of epidemiology, nutritionists, assessment, clinicians, policy researchers, and other cross-cutting arenas of application.

The position is opened until filled.


MARK YOUR CALENDARS– Women's Cancer: Screening and Prevention in 2010

Registration is open for the Case CCC Symposium, Women's Cancer: Screening and Prevention in 2010, May 7 at the Hilton Cleveland East in Beachwood.

Course Overview: Early detection of cancer saves lives. Controversy exists regarding guidelines for cancer screening in women. Mammograms are not consistently obtained and women do not participate in colon cancer screening as frequently as men. Educating practitioners to the benefits of breast, cervical, endometrial, and colorectal cancer screening could help promote health practices. The indications for genetic testing for breast and ovarian cancer susceptibility will be discussed. While practitioners generally understand the harms and benefits of postmenopausal hormone replacement therapy, the specific outcomes with respect to breast and uterine cancer merit further exploration. Discussion of health choices (weight-reduction surgery, prophylactic mastectomy, smoking cessation) and their role in cancer prevention will aid practitioners in guiding patients.

CME credits are available.


FUNDING OPPORTUNITY– Ovarian Cancer Research Fund

The Ovarian Cancer Research Fund is accepting applications for the following opportunities:

Program Project Development Grants: provide funds for ovarian cancer research projects that may involve several investigators within one institution or collaborations between groups in multiple institutions.

Liz Tilberis Scholars awards: are for junior investigators in their first academic faculty appointment. This award is open to physician-scientists (Gynecologic Oncology, Medical Oncology) and PhD scientists.

Ovarian Cancer Research Training Programs of Excellence grant: funds post-doctoral trainees (Gynecologic Oncology or Medical Oncology fellows or PhDs) who are working in established ovarian cancer research groups.

Deadline: June 25


FUNDING OPPORTUNITY– Damon Runyon-Rachleff Innovation Award

The Damon Runyon-Rachleff Innovation Award provides support for the next generation of exceptionally creative thinkers with "high risk/high reward" ideas that have the potential to significantly impact our understanding of and/or approaches to the prevention, diagnosis and treatment of cancer. This award is specifically designed to provide funding for extraordinary early career researchers who have an innovative, new idea but lack sufficient preliminary data to obtain traditional funding. The research supported by the award must be novel, exceptionally creative and, if successful, have the strong potential for high impact in the cancer field.

Eligible applicants (including non-U.S. citizens) must be conducting independent research at a U.S. institution. Institutional nominations are not required and there is no limit to the number of applications that can be received from a particular institution. Basic and translational/clinical projects will be considered and individuals with a background in multiple disciplines are especially encouraged to apply.

Pre-Proposal Deadline: June 1

EVENTS

**All events are open to anyone interested in attending

April 26

Case CCC Special Seminar
Dihua Yu, MD, PhD
Professor and Deputy Chair, Molecular and Cellular Oncology
University of Texas MD Anderson Cancer Center
Topic: New Insights on Breast Cancer Metastasis and Therapeutic Resistance
11 am WRB 3136

Sequencing Data Interest Group (SDIG) Meeting
Peter Scacheri, PhD
Assistant Professor, Genetics
CWRU
Topic: Post-Processing of ChIP-seq Data: How to Find Biological Meaning Within the Mountain of Data
2:30 pm WRB 1413


April 27

Taussig Cancer Institute Core Curriculum Series
Nooshin Hashemi Sadraei, MD
Taussig Cancer Institute
Cleveland Clinic
Topic: New Prognostic and Predictive Tools
12 pm R3-002 Cleveland Clinic

THOR Translational Talk
Michael Kattan, PhD
Professor and Chair, Quantitative Health Sciences
CWRU/ Cleveland Clinic
Topic: Comparative Effectiveness Research in Cancer: The What, The How, The Funding
1 pm R3-027 Cleveland Clinic


April 28

Grand Rounds canceled

Emerging Technologies in Biomedical Research
Michael Snyder, PhD
Professor and Chair, Genetics
Director, Center for Genomics and Personalized Medicine
Stanford University
Topic: RNA-Seq Technology
11 am WRB 1413

Pathology Dissertation Defense
Zhenfeng Zhang
Graduate Student, Pathology
CWRU/ UH
Topic: Study of Molecular Mechanisms of Sensitivity and Resistance to EGFR-Targeted Therapy in Lung Cancer
2 pm WRB 6136

Emerging Technologies in Biomedical Research
Michael Snyder, PhD
Professor and Chair, Genetics
Director, Center for Genomics and Personalized Medicine
Stanford University
Topic: Analysis of Genomes Using Omics Technologies
4 pm WRB 1413


April 29

Taussig Cancer Institute Core Curriculum Series
Pauline Funchain, MD
Taussig Cancer Institute
Cleveland Clinic
Topic: Cancer Genomics: An Introduction to the Principles Behind Personalized Medicine
12 pm R3-002 Cleveland Clinic

Neurosciences Seminar
Zhigang He, PhD
Research Associate, Neurology
Children's Hospital Boston
Topic: Mechanisms of Axon Regeneration
12:10 pm BRB 105

Aging-Cancer-Energetics Seminar
Linda Francis, PhD
Fellow, Prevention Research Educational Postdoctoral (PREP) Training Program
Case CCC/ MetroHealth
Topic: Stress Exposure and Recovery from Bereavement Among Advanced Cancer Caregivers
4 pm BRB 732

Zella Hall Lecture
Eli Glatstein, MD
Professor and Vice Chairman, Radiation Oncology
University of Pennsylvania Medical Center
Topic: Current and Future Innovation in Radiation Oncology
5 pm Rainbow Amphitheater


April 30

Taussig Cancer Institute Grand Rounds
Edwin Alyea, MD
Associate Professor, Medicine
Harvard University/ Dana Farber Cancer Institute
Topic: Non-Myeloblative Allogeneic Transplantation: Efforts to Reduce GVHD and Prevent Relapse
8 am R3/002-003 Cleveland Clinic

Hem/Onc Fellows Seminar
Tycel Phillips, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: Multiple Myeloma
8 am Wearn 137

Mt. Sinai Sidney H. Sachs, MD Surgical Oncology Lectureship
Lee Ellis, MD
Professor, Surgery and Cancer Biology
University of Texas MD Anderson Cancer Center
Topic: Intercellular Crosstalk and Chemoresistance in the Tumor Microenvironment
4 pm (**note time change**) WRB 1413

Cancer Center Research in Progress Seminar
Yiqing Zhao
Graduate Student, Wang Lab, Div. of Hem/Onc
CWRU/ UH
Topic: Identification and Functional Characterization of Paxillin as a Target of Phosphatase PTPRT
4 pm WRB 3136

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Cell Biology Seminar
May 7
Jeffrey Rosen, PhD
Professor, Cell Biology
Baylor College of Medicine
Topic: Therapeutic Targeting of Breast Cancer Tumor Initiating Cells
10 am NC1-202 Cleveland Clinic

Case CCC Scientific Retreat
July 9-10
The Lodge at Sawmill Creek Resort


ADDITIONAL UPCOMING SEMINARS & EVENTS

Midwest Blood Club Symposium
May 6-7
Indiana University School of Medicine
Details

Business Education Course: "The Business of Regenerative Medicine: From Stem Cells to the Market Place"
July 12-15
Dively Building
Details

Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI
Details

International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
October 18-19
Purdue University, West Lafayette, IN
Details


FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (tracy.rehl@case.edu).

Job Description



CASE CCC ON FACEBOOK AND LINKEDIN– Join Us!

We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!


PREVIOUSLY ANNOUNCED OPPORTUNITIES

DOD NFRP Clinical Trial Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Investigator-Initiated Focused Research Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP New Investigator Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD BCRP Concept Award
Pre-Application Deadline: May 12
Application Deadline: May 26

CTSC Pilot Funds
Application Deadline: May 1

ASH Junior Faculty Scholar Award
LOI Deadline: May 1

ASH Fellow Scholar Award
LOI Deadline: May 1

DOD BCRP Idea Award
Application Deadline: May 5

DOD PCRP Health Disparity Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PRMRP Clinical Trial Award
Application Deadline: May 13

DOD PRMRP Technology/Therapeutic Development Awards
Application Deadline: May 13

DOD NFRP Clinical Trial Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Focused Research Award
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Application Deadline: May 20

DOD NFRP New Investigator Award
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Application Deadline: May 20

DOD BCRP Concept Award
Pre-Application Deadline: May 12
Application Deadline: May 26


DOD PCRP Health Disparity Research Award
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Application Deadline: May 26

IOTF Oncology Product Research/Review Fellows
Application Deadline: May 30

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 1

DOD PCRP Idea Development Awards
Application Deadline: June 9

DOD PCRP Synergistic Idea Development Awards
Application Deadline: June 9

DOD OCRP Translational Pilot Award
Application Deadline: June 10

Children's Cancer Research Fund Clinical Pediatric Research Grants
Application Deadline: June 16

DOD BCRP Inter-Institutional Training Award
Application Deadline: June 23

DOD BCRP Multi-Team Award
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Application Deadline: June 23

Ovarian Cancer Research Fund Program Project Development Grants:
Application Deadline: June 25

Ovarian Cancer Research Fund Liz Tilberis Scholars awards
Application Deadline: June 25

Ovarian Cancer Research Fund Ovarian Cancer Research Training Programs of Excellence grant
Application Deadline: June 25

Induced Pluripotent Stem Cell Pilot Research Award
Application Deadline: July 30

DOD PRMRP Investigator-Initiated Research Award
Application Deadline: August 5

IOTF Cancer Prevention Fellows
Application Deadline: September 1

AACR Scholar-in-Training Awards - Special Conferences
Application Deadline varies

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Instructions for Completion and Technical Evaluation of the Vertebrate Animal Section (VAS) in NIH Contract Proposals (NOT-OD-10-049)

Request for Information (RFI): Priorities for the NIH Adherence Research Network (NOT-OD-10-078)

Amendments to PAR-10-165, The National Cancer Institute (NCI) Cancer Education and Career Development Program (R25) (NOT-CA-10-023)

Academic-Industrial Partnerships for Translation of in vivo Imaging Systems for Cancer Investigations (R01)(PAR-10-169)

Research on Malignancies in the Context of HIV/AIDS (R21)(PA-07-454)

Etiology, Prevention, and Treatment of Hepatocellular Carcinoma (R01) (PA-08-243)

Etiology, Prevention, and Treatment of Hepatocellular Carcinoma (R21) (PA-08-244)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.