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Case Comprehensive Cancer Center Newsletter

April 12, 2010

CASE CCC IN THE NEWS

Survivorship Program Helps Ease Changes in Breast Cancer Treatment
Plain Dealer - Apr 5, 2010
In today's video Health Tip, Dr. Halle Moore discusses a breast cancer survivorship program at the Cleveland Clinic that helps patients transition from one ...


NEW MEMBERS CORNER

Please join us in welcoming the newest members of the Case CCC:

Jeffrey M. Hardacre, MD
Assistant Professor, Surgery
Developmental Therapeutics Program

Polly M. Mazanec, PhD, MSN
Assistant Professor, Nursing
Aging-Cancer Research Program

John David Prologo, MD
Assistant Professor, Radiology
Cancer Imaging Program

Paul J. Tesar, PhD
Assistant Professor, Genetics
Cancer Genetics Program


MESSAGE FROM THE DIRECTOR– Effort to Modify Funding and Review of Gene Therapy Protocols

The American Society of Gene and Cell Therapy (ASGCT), recognizing the complexity and funding limits of novel cell and gene therapy, has conducted a full review of this topic, including meetings with program leaders and intramural leadership at NIH. They have formulated a letter to NIH Director, Francis Collins.

For those contemplating initiatives in this area, please the review the opportunities to be involved.

Stan Gerson, MD
Director, Case Comprehensive Cancer Center


AACR ANNUAL MEETING

The following Cancer Center members will be participating in the upcoming American Association for Cancer Research (AACR) Annual Meeting, April 17-21:

James Basilion
Chair: Methods Workshop, Imaging Methods for Preclinical Models of Cancer (Sat, Apr 17 10:15 am-12:15 pm)
Speaker: From a Preclinical Model to a Clinical Trial (Sat, Apr 17 11:45 am)

Donna Hansel
Panelist: Professional Advancement Series Session, Physician-Scientist Pathway: Navigating the Murky Waters Between Clinical Medicine and Research Discovery (Mon, Apr 19 10:30 am-12:30 pm)

Eric Klein
Forum Moderator: Antioxidants and Cancer Prevention: Molecular, Epidemiologic, and Public Perspectives (Mon, Apr 19 5-6:30 pm)

Li Li
Speaker: NCI/NIH-sponsored Session, Parlaying the K Award into Your First R01: How Did They Do It? (Wed, Apr 21 11 am-1 pm)

Sanford Markowitz
Co-Chair: New Concepts in Organ Site Research Session, New Concepts in Colon Cancer Research (Tues, Apr 20 10:30 am-12:30 pm)
Speaker: Genetic Approaches to Early Detection and to Prevention of Colon Neoplasms (Tues, Apr 20 10:30 am)

Jeremy Rich
Chair: Educational Session, Cancer Stem Cells and Treatment Resistance (Sat, Apr 17 10:15 am-12:15 pm)
Speaker: An Evolving Concept of Cancer Stem Cells in Tumor Biology (Sat, Apr 17 10:15 am)

 

Research from the following Cancer Center members will be presented at the meeting:

Minisymposium:

  • Jill Barnholtz-Sloan: Risk and Prognostic Factors of Cancer Session, A Novel FGFR2 Haplotype is Associated with Increased Risk of Breast Cancer in African American Women (Tues, Apr 20 3:40 pm)

Poster Sessions:

Sunday, April 18
2-5 pm

  • Alex Almasan (130)
  • Venugopalan Cheriyath and Ernest Borden (188)
  • Bingcheng Wang (434)
  • James Basilion (582)
  • Brian Rini (630)
  • Stanton Gerson and Lili Liu (682)
  • Patrick Ma and Yanming Wang (836)

Monday, April 19
9 am - 12 pm

  • John Pink, Mark Jackson and Shigemi Matsuyama (1023)
  • Pierre Triozzi and Ernest Borden (1361)
  • Dan Lindner, Ernest Borden and Taolin Yi (1560)
  • Belinda Willard, Ronald Bukowski and Ram Ganapathi (1626)
  • Venugopalan Cheriyath, Matt Kalaycio and Ernest Borden (1684)
  • Ofer Reizes (1719)
  • Paul Elson, Charis Eng and Donna Hansel (1810)
  • Sanjay Gupta (1899)
  • Gary Koski and Greg Plautz (1929)

Monday, April 19
2-5 pm

  • Khalid Sossey-Alaoui (2022)
  • Edward Greenfield (2194)
  • Gregory MacLennan, Pingfu Fu and Sanjay Gupta (2364)
  • Jill Barnholtz-Sloan (2835)

Tuesday, April 20
9 am-12 pm

  • Lili Liu and Stan Gerson (2984)
  • David Danielpour (3123)
  • Charis Eng (3260)
  • Jeremy Rich and Andrew Sloan (3318)
  • Janet Houghton (3341)
  • Eric Hsi (3735)
  • Sanjay Gupta (3801)
  • Sanjay Gupta (3804)

Tuesday, April 20
2-5 pm

  • Alex Almasan (3924)
  • Robert Weil (3934)
  • David Danielpour and Bingcheng Wang (3967)
  • Warren Heston (4057)
  • Cheng-Kui Qu (4296A)
  • Ann-Marie Broom and James Basilion (4341)
  • Brian Rubin (4520)
  • Warren Heston and Zhenghong Lee (4554)
  • Alex Almasan (4689)
  • Jill Barnholtz-Sloan (4724)
  • Li Li and Charis Eng (4731)

Wednesday, April 21
8-11 am

  • Sanjay Gupta (4903)
  • Charis Eng (4911)
  • Bingcheng Wang (5009)
  • Andrew Sloan, David Danielpour, James Basilion, and Bingcheng Wang (5216)
  • Jaroslaw Maciejewski and Eric Hsi (5411)
  • Anjali Advani and Ram Ganapathi (5431)
  • Sanjay Gupta (5714)

CALL FOR APPLICATIONS– Cancer Research Training Award

The NCI is pleased to request applications from qualified candidates for a Cancer Research Training Award (CRTA). The CRTA provides an outstanding opportunity for an individual with a strong interest in understanding how cancer care and cancer control activities influence patterns of care and trends in cancer, specifically in the fields of cancer screening and the use of biomarkers in population-based research. The CRTA appointment is a one- or two-year position with the Applied Research Program, Division of Cancer Control and Population Sciences of the NCI.

This position provides an exciting and unique opportunity to work with leaders in the fields of diet, weight, and physical activity related to cancer and other chronic diseases. The position will allow contact with a large number of scientists representing disciplines of epidemiology, nutritionists, assessment, clinicians, policy researchers, and other cross-cutting arenas of application.

The position is opened until filled.


MARK YOUR CALENDARS– Women's Cancer: Screening and Prevention in 2010

Registration is open for the Case CCC Symposium, Women's Cancer: Screening and Prevention in 2010, May 7 at the Hilton Cleveland East in Beachwood.

Course Overview: Early detection of cancer saves lives. Controversy exists regarding guidelines for cancer screening in women. Mammograms are not consistently obtained and women do not participate in colon cancer screening as frequently as men. Educating practitioners to the benefits of breast, cervical, endometrial, and colorectal cancer screening could help promote health practices. The indications for genetic testing for breast and ovarian cancer susceptibility will be discussed. While practitioners generally understand the harms and benefits of postmenopausal hormone replacement therapy, the specific outcomes with respect to breast and uterine cancer merit further exploration. Discussion of health choices (weight-reduction surgery, prophylactic mastectomy, smoking cessation) and their role in cancer prevention will aid practitioners in guiding patients.

CME credits are available.


EVENTS

**All events are open to anyone interested in attending

April 12

Pathology Research Seminar Series
Lydia Matesic, PhD
Assistant Professor, Biological Sciences
University of South Carolina
Topic: Identification of a Role for the Ubiquitin Ligase Wwp1 in Hypertrophic Cardiomyopathy
12 pm WRB 5136

SDIG Seminar
Mark Adams, PhD
Associate Professor, Genetics
CWRU
Topic: De Novo Bacterial Genome Sequencing: A Velvet Touch is Just the Beginning
2:30 pm WRB 1413

CSCRM and Pediatric Hem/Onc Joint Seminar
Suneet Agarwal, MD, PhD
Instructor, Pediatrics
Harvard University
Topic: Modeling Bone Marrow Failure Syndromes Using Induced Pluripotent Stem Cells
4 pm WRB 3-136

Physiology & Biophysics Seminar
Michael Caplan, MD, PhD
Professor, Cellular and Molecular Physiology
Yale University
Topic: Playing in Traffic: Membrane Protein Sorting in Health and Disease
4 pm SOM E501


April 13

Immunology Seminar
Betsy Pierce, PhD
Postdoctoral Scholar, Pediatric Hematology
CWRU/ UH
Topic: A Role of TNF-alpha Converting Enzyme in Lung Dysfunction Following Bone Marrow Transplant
12 pm WRB 5136

CTSC Seminar
Dorr Dearborn, MD, PhD
Professor, Environmental Health
Director, Swetland Center for Environmental Health
CWRU/ UH
Topic: The Health Impact of Indoor Mold: The Cleveland Perspective
4:30 pm BRB 105


April 14

Grand Rounds canceled

Case CCC Special Seminar
J. Alan Diehl, PhD
Professor, Cancer Biology
Abramson Family Cancer Research Institute
Topic: Probing Molecular Pathways of Tumorigenesis
11 am WRB 3-136

Pathology Graduate Student Seminar
Ashley Rettew
Greenfield Lab, Pathology
CWRU
Topic: Phosphoproteomic and Functional Genomic Screening to Identify Novel Receptor Tyrosine Kinases in Osteosarcoma
12 pm WRB 1413

CSCRM Seminar
Todd McDevitt, PhD
Director, Stem Cell Engineering Center, Georgia Tech
Associate Professor, Biomedical Engineering, Georgia Institute of Technology and Emory University
Topic: Engineering the Morphogenesis of Pluripotent Stem Cells
4 pm NA5-08 Cleveland Clinic


April 15

Taussig Cancer Institute Core Curriculum Series
Ramon Tiu, MD
Associate Staff, Translational Hematology and Oncology Research
Cleveland Clinic
Topic: Understanding the Pathogenesis and Treatment of Myelodysplastic/ Myeloproliferative Overlap Neoplasms
12 pm R3-002 Cleveland Clinic

CTSC/ Case Center for Proteomics and Bioinformatics Seminar
James Bann, PhD
Assistant Professor, Chemistry
Wichita State University
Topic: Modulation of Anthrax Protective Antigen Pore Formation by Histidines
12 pm BRB 932

Neurosciences Seminar
David Corey, PhD
Professor, Neurobiology
Harvard University
Topic: Micromechanics of Sensory Transduction by Inner Ear Hair Cells
12:10 pm BRB 105


April 16

Cancer Center Research in Progress Seminar canceled

Cancer Center Seminar Series/ Blood Club canceled

Taussig Cancer Institute Grand Rounds canceled

Hem/Onc Fellows Seminar
Greg Manson, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: TBA
8 am Wearn 137

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Mt. Sinai Sidney H. Sachs, MD Surgical Oncology Lectureship
April 30
3-5 pm WRB 1413
Lee M. Ellis, MD
Professor of Surgery and Cancer Biology, University of Texas MD Anderson Cancer Center
Topic: Intercellular Crosstalk and Chemoresistance in the Tumor Microenvironment
Reception to follow
Presented by the Case CCC, Ireland Cancer Center, Mt. Sinai Health Care Foundation, and Case Department of Surgery.

Women's Cancer: Screening and Prevention in 2010
May 7
Hilton Cleveland East, Beachwood
Details

Case CCC Scientific Retreat
July 9-10
The Lodge at Sawmill Creek Resort


ADDITIONAL UPCOMING SEMINARS & EVENTS

Clinical Development of Stem Cell Therapies: Scientific, Regulatory and Ethical Considerations
April 12-13
Bethesda, MD
Details

Midwest Tissue Engineering Consortium (M-TEC) Annual Meeting
April 16-17
Wolstein Research Building and Hovorka Atrium
Details

AACR 101st Annual Meeting
April 17-21
Washington, DC
Details

Midwest Blood Club Symposium
May 6-7
Indiana University School of Medicine
Details

Business Education Course: "The Business of Regenerative Medicine: From Stem Cells to the Market Place"
July 12-15
Dively Building
Details

Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI
Details

NCI CANCER BULLETIN

Featured Article
Dutasteride Decreases Prostate Cancer Risk

Cancer Research Highlights
Phase III Lung and Pancreatic Cancer Trials Stopped

Use of Health Care Services May Contribute to Colorectal Cancer Disparities

Complementary and Alternative Medicine Commonly Used by Pediatric Patients

Breast Cancer Study Tests Effects of Zoledronic Acid

Guest Director's Update: James H. Doroshow, Director, NCI Division of Cancer Treatment and Diagnosis
Improving the Efficiency of Clinical Trials–Decreasing Activation Times by Fifty Percent


FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (tracy.rehl@case.edu).

Job Description


CASE CCC ON FACEBOOK AND LINKEDIN– Join Us!

We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!


PREVIOUSLY ANNOUNCED OPPORTUNITIES

DOD BCRP Idea Award
Pre-Application Deadline: April 21
Application Deadline: May 5

DOD PRMRP Technology/Therapeutic Development Awards
Pre-Application Deadline: April 22
Application Deadline: May 13

DOD PRMRP Clinical Trial Award
Pre-Application Deadline: April 22
Application Deadline: May 13

DOD NFRP Clinical Trial Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Investigator-Initiated Focused Research Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP New Investigator Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD BCRP Concept Award
Pre-Application Deadline: May 12
Application Deadline: May 26

CTSC Pilot Funds
Deadline: May 1

ASH Junior Faculty Scholar Award
LOI Deadline: May 1

ASH Fellow Scholar Award
LOI Deadline: May 1

DOD BCRP Idea Award
Application Deadline: May 5

DOD PCRP Health Disparity Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PRMRP Clinical Trial Award
Application Deadline: May 13

DOD PRMRP Technology/Therapeutic Development Awards
Application Deadline: May 13

DOD NFRP Clinical Trial Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Application Deadline: May 20


DOD NFRP Investigator-Initiated Focused Research Award
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Application Deadline: May 20

DOD NFRP New Investigator Award
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Application Deadline: May 20

DOD BCRP Concept Award
Pre-Application Deadline: May 12
Application Deadline: May 26

DOD PCRP Health Disparity Research Award
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Application Deadline: May 26

IOTF Oncology Product Research/Review Fellows
Deadline: May 30

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 1

DOD PCRP Idea Development Awards
Application Deadline: June 9

DOD PCRP Synergistic Idea Development Awards
Application Deadline: June 9

DOD OCRP Translational Pilot Award
Application Deadline: June 10

DOD BCRP Inter-Institutional Training Award
Application Deadline: June 23

DOD BCRP Multi-Team Award
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Application Deadline: June 23

DOD PRMRP Investigator-Initiated Research Award
Application Deadline: August 5

IOTF Cancer Prevention Fellows
Deadline: September 1

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Limited Competition: Administrative Supplements for HIV/AIDS Implementation Science in PEPFAR settings (NOT-AI-10-023)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.