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Case Comprehensive Cancer Center Newsletter

March 15, 2010

CASE CCC IN THE NEWS

Researchers Use Fluidigm Nanofluidic Digital PCR Array to Quantify Mutations in Lung Cancer Gene
GenomeWeb Daily News - Mar 11, 2010
The study, published online this month in Clinical Chemistry, sprung from a collaboration between Fluidigm and the laboratory of Patrick Ma, an assistant ...

Fewer Platelets Could be Used for Some Cancer and Bone-Marrow Transplantation ...
EurekAlert (press release) - Mar 10, 2010
Reducing platelet transfusions, and lowering the threshold on when to administer transfusions could help address frequent shortages in platelet supplies, said Dr. Victor Aquino, associate professor of pediatrics and an author of the study appearing in The New England Journal of Medicine... Institutions participating in the study included Case Western Reserve University (Keith McCrae)...

GU Cancers Symposium 2010: ASCO ASTRO SUO - Prostate cancer: Screening and Prevention - Session Highlights
UroToday - March 9, 2010
... International Prevention Research Institute presented "The Case Against Screening;" Dr. Eric Klein from the Cleveland Clinic then presented his view on ...

Researchers Turn to Neurofeedback to Clear the Fog of Chemo Brain
Plain Dealer - March 8, 2010
... of measurements in patients with multiple sclerosis and advanced cancer," said Dr. Halle Moore, an oncologist at the Clinic's Taussig Cancer Institute. ...

ASCO GU: BP Reveals Hit or Miss for Targeted Tx
MedPage Today - March 8, 2010
Developing or not developing treatment-induced hypertension wouldn't be a reason to stop the drug at this point, said Brian Rini, MD, of the Cleveland ...

ASCO GU: Novel Retrovirus Mimics HIV Transmission
MedPage Today - Mar 6, 2010
The recently-discovered xenotropic murine leukemia related virus -- dubbed XMRV -- likely spreads through contact with blood and semen, Eric A. Klein, MD, ...


KUDOS

Congratulations to former Cancer Center trainee Reema Wahdan-Alaswad (Danielpour Lab), who recently won the following awards: Department of Defense Prostate Cancer Training Award (award declined and NRSA accepted); Ruth L Kirchstein National Research Service Award Individual Fellowship Application (F31); and American Association for Cancer Research (AACR) Women in Cancer Research Scholar Award. Wahdan-Alaswad was a trainee on the Cancer Biology Training Grant March 2009- January 2010.


FUNDING OPPORTUNITY– Damon Runyon-Rachleff Innovation Award

The Damon Runyon-Rachleff Innovation Award provides support for the next generation of exceptionally creative thinkers with "high risk/high reward" ideas that have the potential to significantly impact our understanding of and/or approaches to the prevention, diagnosis and treatment of cancer. This award is specifically designed to provide funding for extraordinary early career researchers who have an innovative, new idea but lack sufficient preliminary data to obtain traditional funding. The research supported by the award must be novel, exceptionally creative and, if successful, have the strong potential for high impact in the cancer field.

Pre-Proposal Deadline: June 1

For details, please click here.


FUNDING OPPORTUNITY– ACS Postdoctoral Fellowships

The American Cancer Society (ACS) is accepting applications for Postdoctoral Fellowships, which support the training of researchers who have received a doctoral degree, to provide initial funding leading to an independent career in cancer research (including basic, preclinical, clinical, cancer control, psychosocial, behavioral, epidemiology, health services and health policy research).

Deadline: April 1

For more information, please click here.


MARK YOUR CALENDARS– CTTE 2010 Short Course: "Cell-Based Therapies & Tissue Engineering"

The Skeletal Research Center will offer the 8th annual short course "Cell-Based Therapies & Tissue Engineering" May 17-20 in Clapp and Millis Hall. This four-day course will involve lectures by eminent scholars, and laboratories and lectures on the "how to" of adult stem cell cultures and cell-scaffold interactions. The course is intended for graduate students, post-graduate students, and health science professionals who are interested in tissue engineering with emphasis on the principles and detailed protocols used or being modeled for direct clinical use. A syllabus from lectures and labs will be available to all registered participants.

For details, please click here.


MARK YOUR CALENDARS– 3rd Annual Business Education Course "The Business of Regenerative Medicine: From Stem Cells to the Market Place"

"The Business of Regenerative Medicine: From Stem Cells to the Market Place" will take place July 12-15 in the Dively Building. This program will bring together an international faculty of business managers, government officials, scientists, engineers, physicians, and academicians in the field of regenerative medicine to focus on key economic/business issues in this emerging healthcare niche. Focus will be on new business models, new leadership and financing strategies, and legal/regulatory hurdles in regenerative medicine. The learning objectives will be to provide exposure to new scientific and medical logics, and newest economic pricing, marketing models and investment logics that make the traditional big-pharma models obsolete. New leadership and initiatives in government, academia, venture capital and public policy will be discussed on the fabric of entrepreneurial principles.

For details please click here.


NCI CANCER BULLETIN

Featured Article
Experimental Drug Benefits Patients with Advanced Prostate Cancer

Cancer Research Highlights
Internal Radiation Effectively Reduces Local Recurrence of Some Endometrial Cancers

Extensive Lymph Node Removal May Improve Survival in Some Women with Endometrial Cancer

Children and Teens Less Likely Than Young Adults to Die of Non-Hodgkin Lymphoma

Older Women Are at Low Risk of New HPV Infections, Infections that Progress to Cervical Cancer

People Continue to Trust Physicians, Despite Increasing Health Information Online

Director's Update
Mapping a Strategic Scientific Vision for the National Cancer Program


shRNA CLONE AVAILABILITY

The deadline to order shRNA constructs through the Small Molecule Screening Core (SMSC) is March 22. Please contact Anna Kondratova (kondraa@ccf.org, 445-3503) for details.

EVENTS

**All events are open to anyone interested in attending

March 15

Pathology Seminar
Ramesh Ganju, PhD
Professor and Vice Chair, Pathology
Ohio State University
Topic: Molecular Mechanisms of Breast Cancer Progression and Metastasis
12 pm WRB 1-413

SDIG Seminar
Neil Molyneaux
Analyst/Programmer, Adams Lab, Genetics
CWRU
Topic: SLATE: A Unix Tool to Facilitate Sequence Sorting and Mapping of Variants to Genome Annotation
2:30 pm WRB 1-413


March 16

Immunology Seminar
Anna Valujskikh
Assistant Staff, Immunology
Cleveland Clinic
Topic: In Remembrance of Things Past: Memory T-cells and Allograft Rejection
12:00 pm WRB 1-413

Cancer Center Special Seminar
Leonard Augenlicht, PhD
Professor, Medicine (Oncology)
Yeshiva University
Topic: Genetic and Nutritional Modulation of Intestinal Tumorigenesis
3 pm WRB 3-136


March 17

Grand Rounds
Lisa Rogers, DO
Professor, Neuro-Oncology
CWRU/ UH
Topic: Recent Advances in Therapy for Leptomeningeal Metastasis
8 am Lerner B-151


March 18

Aging-Cancer-Energetics Seminar cancelled

Neurosciences Seminar
Evan Deneris, PhD
Professor, Neurosciences
CWRU/ UH
Topic: Development of the Brain 5HT System
12:10 pm BRB 105


March 19

Cancer Center Seminar Series/ Blood Club canceled

Hem/Onc Fellows Seminar
Lalitha Nayak, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: From Highly Fatal to Highly Curable- Taming Acute Promyelocytic Leukemia
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Philip Schauer, MD
Director, Bariatric and Metabolic Institute (BMI)
Cleveland Clinic
Topic: Obesity, Cancer and Clinical Implications
8am R3/002-003 Cleveland Clinic

Cancer Center Research in Progress Seminar
Phyllis Frisa, PhD
Senior Research Associate, Jacobberger Lab, Div. of General Medical Sciences- Oncology
Topic: Looking for Landmarks in the G1 Phase of the Cell Cycle: mcm6 Loading on Chromatin and the G1 Restriction Point
4 pm WRB 3-136

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Case CCC Scientific Retreat
July 9-10
The Lodge at Sawmill Creek Resort


ADDITIONAL UPCOMING SEMINARS & EVENTS

Pink the Rink "Q for a Day" to benefit ACS
March 19
Quicken Loans Arena
Details

NSF Regional Grants Conference
March 22-23
CWRU Campus
Details

NCI 3rd Annual Biospecimen Research Network Symposium
March 24-25
Bethesda, Maryland
Details

Midwest Tissue Engineering Consortium (M-TEC) Annual Meeting
April 16-17
Wolstein Research Building and Hovorka Atrium
Details

AACR 101st Annual Meeting
April 17-21
Washington, DC
Details

Midwest Blood Club Symposium
May 6-7
Indiana University School of Medicine
Details

Advanced Training Institute on Health Behavior Theory
July 25-August 1
Madison, WI
Details


FUNDING OPPORTUNITY— Title Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4)

NIH is accepting applications for the "Title Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas" (RC4) (RFA-OD-10-005).

This program will support projects that address research endeavors in specific areas that will benefit from significant three-year funds without the expectation of continued NIH funding beyond this period. The research supported by the program should have high short-term impact, and a high likelihood of enabling growth and investment in biomedical research and development, public health, and health care delivery.

Only applications for projects that require $500,000 or more in total costs per year are expected to be considered for funding.

Proposal Deadline: March 15

For details, please click here.

Case CCC Leadership would like to review potential responses, and can assist in developing themes as responsive to the RFA.



FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (tracy.rehl@case.edu).

Click here to view the job description.


CASE CCC ON FACEBOOK AND LINKEDIN– Join Us!

We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!


PREVIOUSLY ANNOUNCED OPPORTUNITIES

James S. McDonnell 21st Century Research Awards
Deadline: March 17

DOD BCRP Inter-Institutional Training Award
Pre-Application Deadline: March 18
Application Deadline: June 23

DOD BCRP Multi-Team Award
Pre-Application Deadline: March 18
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Pre-Application Deadline: March 18
Application Deadline: June 23

CanLiv's 2010 Translational Research Grants Program for Cancers of the Bile Ducts and Gallbladder - Young Investigator Awards
Deadline Extended: March 19

DOD BCRP Idea Award
Pre-Application Deadline: April 21
Application Deadline: May 5

DOD BCRP Predoctoral Traineeship Award
Pre-Application Deadline: March 24
Application Deadline: April 7

DOD BCRP Postdoctoral Fellowship Award
Pre-Application Deadline: March 24
Application Deadline: April 7

DOD BCRP Era of Hope Scholar Award
Pre-Application Deadline: March 24
Application Deadline: April 7

DOD BCRP Innovator Award
Pre-Application Deadline: March 24
Application Deadline: April 7

DOD Peer Reviewed Medical Research Program (PRMRP) Concept Award
Pre-Application Deadline: March 25
Application Deadline: April 8

DOD Prostate Cancer Research Program (PCRP) Exploration–Hypothesis Development Award
Application Deadline: March 31

DOD Prostate Cancer Research Program (PCRP) Impact Award
Application Deadline: March 31

ACS: Role of Healthcare and Insurance in Improving Outcomes in Cancer Prevention, Early Detection, and Treatment
Deadline: April 1

CTSC Pilot Grants
CWRU, UH and MetroHealth Deadline: April 1
Cleveland Clinic Deadline: April 13

DOD BCRP Predoctoral Traineeship Award
Application Deadline: April 7

DOD BCRP Postdoctoral Fellowship Award
Application Deadline: April 7

DOD BCRP Era of Hope Scholar Award
Application Deadline: April 7

DOD BCRP Innovator Award
Application Deadline: April 7

DOD Peer Reviewed Medical Research Program (PRMRP) Concept Award
Application Deadline: April 8

DOD Peer Reviewed Medical Research Program (PRMRP) Technology/Therapeutic Development Awards
Pre-Application Deadline: April 22
Application Deadline: May 13

DOD Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award
Pre-Application Deadline: April 22
Application Deadline: May 13

DOD NFRP Clinical Trial Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Investigator-Initiated Focused Research Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP New Investigator Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Pre-Application Deadline: April 29
Application Deadline: May 20

DOD BCRP Idea Award
Application Deadline: May 5

DOD PCRP Health Disparity Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26


DOD PCRP Laboratory - Clinical Transition Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Pre-Application Deadline: May 5
Application Deadline: May 26

DOD Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award
Application Deadline: May 13

DOD Peer Reviewed Medical Research Program (PRMRP) Technology/Therapeutic Development Awards
Application Deadline: May 13

DOD NFRP Clinical Trial Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Research Award
Application Deadline: May 20

DOD NFRP Investigator-Initiated Focused Research Award
Application Deadline: May 20

DOD NFRP Exploration–Hypothesis Development Award
Application Deadline: May 20

DOD NFRP New Investigator Award
Application Deadline: May 20

DOD NFRP Postdoctoral Traineeship Award
Application Deadline: May 20

DOD PCRP Health Disparity Research Award
Application Deadline: May 26

DOD PCRP Health Disparity Training Award
Application Deadline: May 26

DOD PCRP Laboratory - Clinical Transition Award
Application Deadline: May 26

DOD PCRP Physician Research Training Award
Application Deadline: May 26

DOD PCRP Population-Based Research Award
Application Deadline: May 26

DOD PCRP Prostate Cancer Training Award
Application Deadline: May 26

IOTF Oncology Product Research/Review Fellows
Deadline: May 30

DOD Prostate Cancer Research Program (PCRP) Idea Development Awards
Application Deadline: June 9

DOD Prostate Cancer Research Program (PCRP) Synergistic Idea Development Awards
Application Deadline: June 9

DOD Ovarian Cancer Research Program (OCRP) Translational Pilot Award
Application Deadline: June 10

DOD BCRP Inter-Institutional Training Award
Application Deadline: June 23

DOD BCRP Multi-Team Award
Application Deadline: June 23

DOD BCRP Transformative Vision Award
Application Deadline: June 23

DOD Peer Reviewed Medical Research Program (PRMRP) Investigator-Initiated Research Award
Application Deadline: August 5

IOTF Cancer Prevention Fellows
Deadline: September 1

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Common Pathogenetic Mechanisms of Lung Cancer and COPD (R01) (RFA-HL-11-002)

Understanding and Promoting Health Literacy (R01)(PAR-10-133)

Understanding and Promoting Health Literacy (R03)(PAR-10-134)

Understanding and Promoting Health Literacy (R21)(PAR-10-135)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.