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Case Comprehensive Cancer Center Newsletter

November 22, 2010


UH Launches Urology Institute
MD News (press release) - Nov 17, 2010
Directed by Dr. Lee Ponsky, the Center delivers state-of-the-art disease management through a multidisciplinary team approach in which urologic oncologists ...

NCI Recognizes Clinical Investigators with Team Leadership Award
NCI Cancer Bulletin - Nov 16, 2010
NCI has announced the recipients of its Cancer Clinical Investigator Team Leadership Award for 2010, recognizing exceptional contributions to the advancement of new therapies through collaborative team science: ...Dr. Smitha Krishnamurthi, Case Comprehensive Cancer Center...

Soda Seen as a Possible Cancer Fighter
AOL Health - Nov 12, 2010
"It doesn't surprise me that the material you ingest alongside an oral medication will affect how that medication is absorbed," Dr. Neal Meropol, ...

Reimbursement Notes: UnitedHealthcare Tightens Coverage Policy for Bevacizumab
Oncology Times - Nov 10, 2010
Neal J. Meropol, MD, the Dr. Lester E. Coleman, Jr. Professor of Cancer Research and Therapeutics and Chief of the Division of Hematology and Oncology, University Hospitals Case Medical Center and Case Western Reserve University,...

Study Finds No Link Between High-Carb Diet, Colon Cancer
AOL Health - Nov 4, 2010
... cancer," Dr. Gregory Cooper, director of the Gastrointestinal Cancer Center at University Hospitals Case Medical Center in Cleveland, told AOL Health. ...


New Clinical Research Office Administrative Director

The Cancer Center would like to welcome Katarzyna Karelus as Administrative Director of the Clinical Research Office. In this role Katarzyna will support Drs. Afshin Dowlati, Smitha Krishnamurthi, John Sweetenham and Neal Meropol in overseeing clinical research operations for the Case CCC, including Redbook, PRMC, Data Safety and Toxicity Committee, as well as Cancer Center resources designated for clinical research.


Cell Death Regulation Program Meeting

The Cell Death Regulation Program (Program 2) will continue its monthly research meetings. The next meeting with be Thursday, December 9 from 4-6 pm in Wolstein Research Building 3-136. Refreshments will be provided. Please contact Kristin Waite with any questions.

Lili Liu, PhD: Synthetic Lethality: A New Therapeutic Strategy for the Treatment of CLL Disease
Clark Distelhorst, PhD: Novel Concepts About the Role of Bcl-2 in CLL
Alex Almasan, PhD: TBD

Cancer Health Disparities Summit

The Cancer Health Disparities Summit 2011 will be July 13-15, 2011 at the Bethesda North Marriott Hotel in Rockville, Maryland. Look for additional details on the Center to Reduce Cancer Health Disparities website.


November 14, 2010

Featured Article: HHS Releases New Tobacco Control Strategy for the Nation

Mutated Gene Linked to Poor Survival in Acute Myeloid Leukemia

Novel Drug Effectively Shrinks Tumors in Hodgkin Lymphoma

Indefinite Imatinib Therapy May Not Be Necessary for Some CML Patients

Lasofoxifene Is Potential New Option for Breast Cancer Risk Reduction

Some Cells in Stroma May Block Immune System's Antitumor Effects

In Depth
Low-Dose CT Shows Clear Mortality Benefit for Lung Cancer Screening in Heavy Smokers

Uncertain Road for Potential Ewing Sarcoma Therapy

Featured Clinical Trial: Combination Therapy for Advanced Kaposi Sarcoma

Families and Scientists Gather to Discuss Research and Treatment for Li-Fraumeni Syndrome


Legislative Update

Cancer.gov Update



CTSC Pilot Funding

The Clinical and Translational Science Collaborative (CTSC) announces the December 1, 2010 quarterly competition for core utilization pilot funding of up to $10,000 to support activities provided by any of the CTSC Core facilities. This program is being supported by CWRU, UH, and MetroHealth Medical Center, and investigators whose primary appointments are based at these sites are eligible for this competition. Details and instructions will be posted on the CTSC website. Please contact the CTSC research concierge with any questions.

Investigators at the Cleveland Clinic have access to internal pilot funds for clinical and translational research through the RPC Program. Information and details can be found on the Lerner Research Institute website. Click "Apply" on the right sidebar for the on-line application. Contact Charlotte Bhasin with any questions about the Cleveland Clinic program.



**All events are open to anyone interested in attending

November 22

SDIG Meeting
Gokhan Yavas, PhD
Topic: Algorithms to Detect Tandem Duplications in Cancer Genome Using Paired-End NGS Data
2:30 pm WRB 1-403

Physiology and Biophysics Seminar
Nicole Steinmetz, PhD
Assistant Professor, Biomedical Engineering
Topic: Engineering Viral Nanoparticles as Smart Devices for Nanomedicine
4 pm SOM E501

November 23

Physiology and Biophysics Seminar
Vera Moiseenkova-Bell, PhD
Assistant Professor, Pharmacology
Topic: Hot on the Trail of TRP Channels Structure
12 pm SOM E501

Taussig Cancer Institute Core Curriculum Series
Matt Kalaycio, MD
Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: CML
12 pm R3-002 Cleveland Clinic

November 24

Hematology and Oncology Division Research Conference canceled

Ribonucleotide Reductase Journal Club
Sanath Wijerathna
Graduate Student, Dealwis Lab, Pharmacology
Topic: Structural Basis for Allosteric Regulation of Human Ribonucleotide Reductase by Nucleotide-Induced Oligomerization
2 pm SOM W331

November 25

Happy Thanksgiving!

November 26

Cancer Center Seminar Series canceled

Cancer Center Research in Progress Seminar canceled

Hematology and Oncology Fellows Seminar canceled

Taussig Cancer Institute Grand Rounds canceled


Case CCC Calendar

LRI Calendar


Department of Genetics, Office of Graduate Education, Minority Graduate Education Student Organization, and PREP Program Seminar
December 8
11 am BRB 105
Dr. Guillermina Lozano
Professor and Chair, Department of Genetics
MD Anderson Cancer Center
Topic: Modulating p53 Activity for Better or for Worst
Contact Melana Bey if you are interested in meeting with Dr. Lozano.


Active Living Research Annual Conference
February 22-24, 2011
San Diego, CA
Call for Abstracts Deadline: August 6

Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals
March 4-5, 2011
Las Vegas, Nevada

4th Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science
March 28-29, 2011
Bethesda North Marriot Hotel & Conference Center in Bethesda, Maryland

Call for Abstracts: 2011 Clinical and Translational Research and Education Meeting: ACRT/SCTS Joint Annual Meeting
April 27-29, 2011
Omni Shoreham, Washington, DC
Abstract Deadline: December 16


NCRM Stem Cell-related Pilot Projects (SCPP)
Deadline: November 22

AACR-Women in Cancer Research (WICR) Scholar Awards
Deadline: November 30

International Clinical Research Fellows (ICRF) Program
Deadline: December 1

Sidney Kimmel Scholar Award
Deadline: December 1

Sidney Kimmel Translational Science Award
Deadline: December 1

DOD CDMRP Breast Cancer Postdoctoral Fellowship Award
Application Deadline: December 2

Susan G. Komen for the Cure Promise Grants
Full Application Deadline: December 7

DOD LCRP Lung Cancer Early Detection Clinical Consortium
Application Deadline: December 7

Landon Foundation-AACR INNOVATOR Award for International Collaboration
Deadline: December 8

Landon Foundation-AACR INNOVATOR Award for Cancer Prevention Research
Deadline: December 8

Landon Foundation-AACR INNOVATOR Award for Research in Personalized Cancer Medicine
Deadline: December 8

AACR Basic Cancer Research Fellowships
Deadline: December 13

AACI Translational Cancer Research Fellowship
Deadline: December 17

Susan G. Komen for the Cure Postdoctoral Fellowships
Full Application Deadline: January 5, 2011

Susan G. Komen for the Cure Post Baccalaureate Training in Disparities Research
Full Application Deadline: January 5, 2011

Prostate Cancer Foundation (PCF) 2011 Creativity Awards
Deadline: January 13, 2011

SU2C Innovative Research Grants
Application Deadline: January 31, 2011

2011 Jane Coffin Childs Memorial Fund for Medical Research Fellowship Awards
Deadline: February 1, 2011

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Special Conferences
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Updated Application Guides and Non-competing Continuation Progress Report Instructions Posted (NOT-OD-11-022)

Correction to RFA-CA-10-017, Scientific Meetings for Creating Interdisciplinary Research Teams in Basic Behavioral and Social Science Research (R13), in Order to Simplify Submission Requirements (NOT-CA-11-001)

Institutional Clinical and Translational Science Award (U54) (RFA-RM-10-020)

Limited Competition: Fogarty International Research Collaboration - Behavioral and Social Sciences (FIRCA-BSS) Research Award (R03) (PAR-11-036)

Limited Competition: Fogarty International Research Collaboration - Basic Biomedical (FIRCA-BB) Research Award (R03) (PAR-11-037)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.