October 18, 2010
CANCER CENTER SEMINAR SERIES
Neurofibromatosis: Timing and Targets
Friday, October 22, 2010
Please join us Friday, October 22 at the Cancer Center Seminar Series and hear guest speaker Nancy Ratner, PhD present Neurofibromatosis: Timing and Targets.
Dr. Ratner's laboratory is interested in peripheral nerve glia known as Schwann cells. They study Schwann cells during normal development, and during abnormal development associated with tumor formation. The current focus of our research is genetic mutations in tumor suppressor genes and the effect of these mutations on Schwann cell development. These genes are thought to contribute to carcinogenesis when mutant or lost. Schwann cell tumors develop in humans who inherit mutations in two of these tumor supressor genes, neurofibromatosis type 1 (NF1) and neurofibromatosis type 2 (NF2). Mechanistic analysis of Ras (a modulatoryNF1 activity) pathways and cytoskeleton- Rac (a member of the RhoGTPase family involved in NF2 signaling) intracellular signaling pathways in Schwann cells disrupted by mutations in these genes are being actively investigated. We are using transgenic mouse models, and cells from primary human tumors to define cellular changes that lead to Schwann cell tumor formation, secondary to mutations in the NF1 and NF2 genes.
CASE CCC IN THE NEWS
Lack of Sleep Linked to Risky Colon Polyps
First GvHD Symposium to Bring Nation's Leading Blood Cancer and Bone Marrow Transplant Specialists to Cleveland
National Breast Cancer Awareness Month
For National Breast Cancer Awareness Month, the CWRU Bookstore will donate $1 for every fan on Facebook who changes his or her profile picture to the pink awareness ribbon (It's currently the Bookstores profile picture; you can save it to your desktop to use) and then comments on the Bookstores Facebook page so that the ribbon photo can be seen by all. You needn't keep the ribbon as your picture for the entire month, just until you leave the comment. Join the Bookstore at Facebook to help make a difference.
DOD CDMRP Breast Cancer Postdoctoral Fellowship Award
Applications are currently being accepted for the DOD Congressionally Directed Medical Research Programs (CDMRP) Breast Cancer Postdoctoral Fellowship Award. This Award supports exceptionally talented recent medical or other doctoral graduates performing innovative, high-impact breast cancer research during their postdoctoral training, and allows them to obtain the necessary experience for an independent career at the forefront of breast cancer research. Candidates for this award should exhibit a strong desire to pursue a career in breast cancer research.
As of the application submission deadline, all eligible PIs must have: been in the laboratory, in which the proposed research is to be performed, for no more than 2 years; a total of less than 4 years of postdoctoral research experience (excluding clinical residency or fellowship training); and successfully completed the requirements for a doctoral or medical degree.
Pre-Application Deadline: November 18
National Center for Regenerative Medicine Stem Cell-related Pilot Projects
The National Center for Regenerative Medicine (NCRM) is accepting proposals for funding of Stem Cell-related Pilot Projects (SCPP) for the period from February 1, 2011 – January 31, 2012. Current funds for this program come from the April 2009 award from the Research Commercialization Program (RCP) of $5 million which includes $200,000 annual funding for pilot projects. Additional funds of up to $50,000 from the CWRU Clinical and Translational Science Collaborative (CTSC) for Core Utilization Pilot Awards will be added into this year's funds. With CTSC Core Facility usage, NCRM can provide up to five $50,000 grants this year to promote new projects in stem cell research. In addition to providing seed money for new research ideas, priority will be given to projects that bring new researchers into the stem cell arena or provide funding to researchers not currently receiving NCRM research support. Projects must have a clinical and/or commercial direction though it may be more rudimentary than for a fully developed project.
Deadline: November 22
Proposals must be submitted in electronic format using either Word or PDF files though the WebGrants portal ID number 1247 – National Center for Regenerative Medicine: Stem Cell Pilot.
SU2C Innovative Research Grants
The SU2C Innovative Research Grants are an effort to support the next generation of extraordinary leaders in their quest to conquer cancer. These grants will provide substantial funding to scientists whose novel, high-risk, high-reward cancer research proposals have significant potential for translational application, and hold great promise for advancing SU2C's overarching goal of improving and saving the lives of patients. It is the hope that ideas for new Stand Up To Cancer Dream Teams will emerge from these Innovative Research Grants, and this criterion will be given a high priority in the evaluation of the Letters of Intent. Research projects that are already being supported by the National Institutes of Health (NIH) R01 grants or the equivalent will not be accepted.
LOI Deadline: November 15
2011 Pancreatic Cancer Action Network-AACR Grants Program
The Pancreatic Cancer Action Network, in partnership with AACR, is accepting applications for the following opportunities:
Pancreatic Cancer Action Network-AACR Pathway to Leadership Grants: Represent a joint effort to ensure the future leadership of pancreatic cancer research by supporting outstanding early career investigators beginning in their postdoctoral research positions and continuing through their successful transition to independence. Applicants must have started their postdoctoral or clinical research fellowship on or after July 2, 2006, and not already have a full-time tenure track assistant professor position (or equivalent).
Pancreatic Cancer Action Network-AACR Fellowship: Represents a joint effort to encourage and support postdoctoral and clinical research fellows who are in the first three years of their fellowship training (at the start of the grant term) to conduct pancreatic cancer research and establish successful career paths in this field. The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.
Pancreatic Cancer Action Network-AACR Career Development Awards: Represent a joint effort to encourage and support junior faculty who are in the first 4 years of a faculty appointment (at the start of the grant term) to conduct pancreatic cancer research and establish successful career paths in this field. The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.
Deadline for all opportunities: October 27
MARK YOUR CALENDARS
2010 Conference on Clinical Cancer Research
Registration is still open for the 2010 Conference on Clinical Cancer Research, October 20 at Westin City Center in Washington, DC. Hosted by the Engelberg Center for Health Care Reform at Brookings and Friends of Cancer Research, and supported by the American Association for Cancer Research, the American Society of Clinical Oncology, and Susan G. Komen for the Cure, conference participants will join together to address specific challenges in clinical cancer research and discuss potential solutions proposed by expert panels. Panelists and participants represent the range of stakeholders in the cancer community, including senior officials from the U.S. Food and Drug Administration (FDA) and National Cancer Institute (NCI), as well as thought leaders from academia, patient advocacy organizations, and the life sciences industry.
Conference highlights include keynote addresses from FDA Commissioner Dr. Margaret Hamburg and NCI Director Dr. Harold Varmus, as well as four interactive panel discussions on:
Oncomine Hands-On Workshop
The first hands-on Oncomine workshop for registered users is scheduled for Wednesday, October 27 at 2 pm. The workshop will cover the basics of navigation in this valuable database. For access to the Oncomine database, visit http://www.oncomine.com and register using your Case.edu or CCF.org email address. You will then need to sign up for the limited space hands-on tutorial workshop on October 27 by emailing Patrick.Leahy@case.edu. Extra sessions will be run if necessary. Please contact Patrick Leahy with any questions.
**All events are open to anyone interested in attending
Pathology Research Seminar
Physiology and Biophysics Seminar
Taussig Cancer Institute Core Curriculum Series
Developmental Therapeutics Program Meeting canceled
Hematology/Oncology Special Seminar
Pathology Graduate Student Seminar
LRI Showcase Seminar
Cell Death Regulation Meeting
Cancer Center Research in Progress Seminar canceled
Hematology and Oncology Fellows
Cancer Center Seminar Series
UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS
Cancer Center Scientific Series
Case CCC Clinical Research Retreat
ADDITIONAL UPCOMING SEMINARS & EVENTS
2010 Cleveland Nanomedicine Summit
International Symposium on Breast Cancer Prevention: Nutrition, Communication and Public Policy
ASCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer
Conference on Clinical Cancer Research
2010 International Conference of RNA Nanotechnology and Therapeutics
Graft versus Host Disease Conference
Active Living Research Annual Conference
Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals
4th Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science
Call for Abstracts: 2011 Clinical and Translational Research and Education Meeting: ACRT/SCTS Joint Annual Meeting
PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
DOD Peer Reviewed Cancer Research Program (PRCRP) Idea Awards
Susan G. Komen for the Cure Promise Grants
NIH BULLETIN – Notices and Funding Opportunities
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
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