January 19, 2010
CASE CCC IN THE NEWS
Green Tea May Cut Smokers' Lung Cancer Risk
Drug Shows Promise as New Treatment for Gut Tumor
Bing-Cheng Wang, PhD has been invited to speak at the 2010 Molecular Medicine Workshop, May 6-9 in Camogli-Portofino Vetta, Italy. Dr. Wang will present Akt-EphA2 Crosstalk in Invasive Tumor Progression. The workshop will focus on the role of guidance molecules (such as ephrins,semaphorins, netrins, etc.) in different functional contexts related to cancer. The deadline for registration and abstract submission is February 1.
CASE CCC CORE FACILITIES FAIR HIGHLIGHTS ROLES OF FACILITIES IN CANCER RESEARCH
The Cancer Center's 19 core facilities were highlighted at the recent Case CCC Core Facilities Fair, held the afternoon of Wednesday, January 13 in Wolstein Atrium and Auditorium. The purpose of the event was to raise awareness of the shared resources that are available to members and others within the cancer research community. The afternoon included presentations by two Cancer Center core facility directors: James Jacobberger, PhD, Director of the Cytometry and Imaging Microscopy Core, and Christopher Flask, PhD, Director of the Imaging Research Core. Following the presentations, attendees viewed posters and recent work of all Case CCC core facilities and had the opportunity to talk with core directors, managers and staff.
Both speakers presented the capabilities of their facilities and encouraged attendees to consider how the services could be further applied to research taking place in Cancer Center scientific programs. They also invited investigators to suggest new applications that would be helpful to them.
During his talk, Dr. Jacobberger explained the different qualities of cytometry and confocal microscopy, two methods of cell data collection that often are used as complements to provide a more complete analysis of a single cell. Images illustrated the strengths of each approach: cytometry's ability to capture live cell cycles and microscopy's capacity to measure a cell's changes. He also discussed the importance of laser scanning cytometry, which allows for the subcellular localization analysis. He said cell cycling models are complex and difficult to show, and that platform integration is a key to understanding biochemical systems.
In the subsequent presentation, Dr. Flask noted the important capability of in vivo imaging as an element of the Imaging Research Core. As an example, it allows tracking the effect of contrast agents' uptake pre- and post-therapy, showing whether status is being maintained or is being modulated, and targeting low amounts of radiotracers. The Imaging Core focuses on physiologic/biologic questions that are not yet being addressed in medicine. Dr. Flask added that the core aids in proof of concept experiments, and can house and maintain animals that investigators are studying for up to three months. He also said that because of the broad scope of imaging research in many clinical fields, the core already has demonstrated its potential to bring together disciplines and strengthen collaboration among the Cancer Center's diverse programs.
Wednesday's program is the first in a series of Case CCC Core Facilities Fairs planned for 2010 by Cancer Center Director Stan Gerson, MD. Dr. Gerson believes that there is much to be gained when directors explain the roles each core has in cancer research. Mark Schluchter, PhD, Director of the Biostatistics Core, concurs, saying, "One of the challenges that the Biostatistics Shared Resource and other Cancer Center cores face is that not all Cancer Center investigators are aware of our existence or of the kinds of services we can provide. We are always interested in reaching new members and this fair and other events like it help showcase the cores and what we do."
Pat Faller and Kristin Waite contributed to this story.
CALL FOR APPLICATIONS– 2010 NASA Space Radiation Summer School
Applications are now being accepted for the 2010 NASA Space Radiation Summer School. Up to 15 students will be selected for the course to be held this summer at the Brookhaven National Laboratory (BNL) in Long Island, NY from May 20 – June 11. The goal of the course is to provide scientific and practical information to students and scientists who are either new to the NASA program or to charged particle radiobiology. At the completion of the summer school, students will have received the full complement of training required to conduct their own experiments at BNL.
Both foreign nationals and US citizens may apply to the program. All selected students must satisfy BNL and Department of Energy safety and security requirements in order to be admitted. Due to the intense nature of the course, applicants must demonstrate oral and written proficiency in the English language.
Deadline: February 28
For more information, please click here.
NCI CANCER BULLETIN
Cancer Research Highlights
Guest Director's Update: Andrea M. Denicoff and Dr. Jeffrey S. Abrams
FUNDING OPPORTUNITY— Title Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4)
NIH is accepting applications for the "Title Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas" (RC4) (RFA-OD-10-005).
This program will support projects that address research endeavors in specific areas that will benefit from significant three-year funds without the expectation of continued NIH funding beyond this period. The research supported by the program should have high short-term impact, and a high likelihood of enabling growth and investment in biomedical research and development, public health, and health care delivery.
This FOA solicits applications proposing to develop and implement critical research innovations in one or more of the following five thematic areas:
Only applications for projects that require $500,000 or more in total costs per year are expected to be considered for funding.
LOI Deadline: February 15 (requested, not required)
For details, please click here.
Case CCC Leadership would like to review potential responses, and can assist in developing themes as responsive to the RFA.
**All events are open to anyone interested in attending
Taussig Cancer Institute Core Curriculum Series
CTSC Seminar Series
CSCRM Seminar and Poster Presentation
Lerner Research Institute Showcase Seminar
Developmental Therapeutics Meeting cancelled
Cancer Trainee Seminar Series
Taussig Cancer Institute Core Curriculum Series
Hem/Onc Fellows Seminar
Taussig Cancer Institute Grand Rounds
Cell Biology Seminar
Cancer Center Seminar Series/ Blood Club
Cancer Center Research in Progress Seminar
UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS
Case CCC Scientific Series- TREC
Olof Pearson Lecture
Case CCC Scientific Retreat
ADDITIONAL UPCOMING SEMINARS & EVENTS
12th International Symposium on Anti-Angiogenic Agents: Angio 2010 Recent Advances and Future Directions in Basic and Clinical Cancer Research
AACR-JCA 8th Joint Conference on Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics
13th Annual Meeting of the Translational Research Cancer Centers Consortium
AACR 101st Annual Meeting
MARK YOUR CALENDARS– Case CCC Scientific Series: TREC
Please mark your calendars for the next installment of the Case CCC Scientific Series and reception on January 28 from 4:00-7:00 pm in Wolstein Auditorium (WRB 1413). Presentations will be related to the Case Transdisciplinary Research on Energetics and Cancer (TREC) Center, led by Dr. Nathan Berger:
•Stephanie Doerner: Diet, Obesity and Susceptibility to Colon Cancer
Everyone is welcome and encouraged to attend.
FUNDING OPPORTUNITY– Damon Runyon Cancer Research Foundation Clinical Investigator Award
CWRU SOM has been invited to nominate up to three individuals for the Damon Runyon Cancer Research Foundation Clinical Investigator Award. This award supports young physician-scientists conducting patient-oriented cancer research, with a goal of increasing the number of physicians capable of moving seamlessly between the laboratory and the patient's bedside in search of breakthrough treatments.
If you are interested in applying for this award, please submit the following materials to firstname.lastname@example.org by Wednesday, January 20: biosketch and a one-paragraph description of how your research fits the description of "Clinical Research" as described by the Damon Runyon Foundation.
Internal Deadline: January 20
For details, please click here.
CASE CCC ON FACEBOOK AND LINKEDIN– Join Us!
We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.
We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!
CALL FOR APPLICATIONS– K12 Clinical Oncology Research Training Program
The Case CCC invites applications for its two-year NCI-funded K12 Clinical Oncology Research Training Program, led by Stanton Gerson, MD, Director, and Alvin Schmaier, MD, Co-Director.
This career development program provides interdisciplinary training in clinical and translational oncology research for clinical oncologist who are interested in pursuing academic research careers as oncology physician scientists.
Application Deadline: February 28
For more information and application materials, please click here.
MARK YOUR CALENDARS– NCI 3rd Annual Biospecimen Research Network Symposium
Registration is now open and abstracts are being accepted for NCI's 3rd Annual Biospecimen Research Network Symposium, Advancing Cancer Research Through Biospecimen Science, March 24-25 in Bethesda, Maryland. The symposium will address the significant impact of pre-analytical biospecimen variables on cancer research and molecular medicine. Hosted by NCI's Office of Biorepositories and Biospecimen Research, the meeting will bring together leaders in the fields of biospecimen research, genomics, proteomics, oncology, pathology, biobanking, hospital administration and pharmaceutics as well as patient advocates.
For details, please click here.
FACULTY CANDIDATE SEARCH– Associate Director for Basic Research
The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (email@example.com).
Click here to view the job description.
PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES
Landon Foundation-AACR INNOVATOR Grant for Research in Personalized Cancer Medicine
Ohio Cancer Research Associates
NIH Bulletin – Notices and Funding Opportunities
Participation of NCI in RFA-OD-10-001, ARRAOS: Recovery Act Limited Competition: Behavioral Economics for Nudging the Implementation of Comparative Effectiveness Research: Clinical Trials (RC4) (NOT-CA-10-012)
Participation of NCI in RFA-OD-10-002, ARRAOS: Recovery Act Limited Competition: Behavioral Economics for Nudging the Implementation of Comparative Effectiveness Research: Pilot Research (RC4) (NOT-CA-10-013)
Participation of NCI in RFA-OD-10-008, Recovery Act Limited Competition: Comparative Effectiveness Research on Upper Endoscopy in Gastroesophageal Reflux Disease (GERD), Eradication Methods for Methicillin Resistant Staphylococcus aureus (MRSA), and Dementia Detection and Management Strategies (RC4) (NOT-CA-10-014)
Gillian Irwin Todd
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Cleveland, Ohio 44106-5065
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