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Case Comprehensive Cancer Center Newsletter

January 11, 2010


Dr. Jeremy Rich recently received a Researching Brain Cancer Award from the McDonnell Foundation for his project, Microenvironmental Reprogramming of Glioma Cells.

The following Cancer Center members were awarded pilot funding from the Clinical and Translational Science Collaborative (CTSC) to support studies conducted through the CTSC Core Facilities:

  • Clemens Burda, PhD: Dual-Receptor Targeted Nanoparticles for the Photodynamic Therapy of Brain Cancer
  • Eckhard Jankowsky, PhD: Identification of Cellular RNA Targets of the DEAD-box RNA Helicase Ded1p

Hematology & Oncology Fellow Brian Grimberg, PhD recently received the Excellence in Science Award from American Association for the Advancement of Science (AAAS) for his long-time leadership of the CWRU Postdoctoral Research Association, drug discovery efforts, and investigations of erythrocyte surface receptors. Dr. Grimberg received a top score on his K22 award last year, which also contributed to him winning the AAAS award.


NIH recently issued a notice regarding the salary limitation for grant and cooperative agreement awards and extramural research and development contract awards. Effective January 1, 2010, the Executive Level I salary level increased to $199,700. Click here for more information.


The Mary Kay Foundation has released a Call for Applications for their Cancer Research Grant Program. This non-profit public foundation focuses on funding research for innovative grants for translational research in ovarian, uterine, breast or cervical cancer. Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer.

Only ONE application per institution is allowed. Investigators interested in applying must submit their biosketch and a one-paragraph description to gillian.irwin@case.edu by Monday, January 11.

Internal Deadline: TODAY, January 11
External Deadline: February 12

For details, please click here.

FUNDING OPPORTUNITY– Ohio Cancer Research Associates

Seed money grants awarded by Ohio Cancer Research Associates are made to support research activities broadly related to cancer and leukemia. The organization seeks to fund research that will lead to continued support at the national level. Applicants must be within six years of their first independent research or faculty appointment.

Deadline: February 19

For details, please click here.


Hope Street Kids, a non-profit organization dedicated to the elimination of childhood cancer through advocacy, education, and the support of pioneering research in pediatric oncology, invites applications for funding of projects in the following areas: (Priority ordered)

  • Basic, translational, clinical, and applied research projects and fellowships
  • Palliative and pain management or procedural pain management associated with cancer and treatment
  • Behavioral intervention projects to support children and their families as they cope with cancer diagnosis and treatment
  • Psychosocial research directed at understanding and improving the impact of cancer and cancer treatment on children and their families.

Deadline: March 1

For more information please click here.

MARK YOUR CALENDARS– Case CCC Core Facilities Fair

The Case CCC Core Facilities Fair is scheduled for Wednesday, January 13 from 3:00 pm - 6:00 pm in Wolstein Atrium and Auditorium.

Featured speakers are Dr. James Jacobberger, Professor, General Medical Sciences (Oncology), who will present Cell Cycle and Cell Signaling Cytometry at 3:00 pm, and Dr. Christopher Flask, Assistant Professor, Radiology, who will discuss Cancer Imaging Research and the Case Center for Imaging Research at 4:00 pm.

Core directors and managers will be present to discuss how their facilities are available to support your research. The afternoon will be filled with core facility related presentations, posters, food and more! We are hoping all members will attend; please encourage your graduate students and lab staff to drop by also.

MARK YOUR CALENDARS– NCI 3rd Annual Biospecimen Research Network Symposium

Registration is now open and abstracts are being accepted for NCI's 3rd Annual Biospecimen Research Network Symposium, Advancing Cancer Research Through Biospecimen Science, March 24-25 in Bethesda, Maryland. The symposium will address the significant impact of pre-analytical biospecimen variables on cancer research and molecular medicine. Hosted by NCI's Office of Biorepositories and Biospecimen Research, the meeting will bring together leaders in the fields of biospecimen research, genomics, proteomics, oncology, pathology, biobanking, hospital administration and pharmaceutics as well as patient advocates.

For details, please click here.

CALL FOR APPLICATIONS– K12 Clinical Oncology Research Training Program

The Case CCC invites applications for its two-year NCI-funded K12 Clinical Oncology Research Training Program, led by Stanton Gerson, MD, Director, and Alvin Schmaier, MD, Co-Director.

This career development program provides interdisciplinary training in clinical and translational oncology research for clinical oncologist who are interested in pursuing academic research careers as oncology physician scientists.

Application Deadline: February 28
Start Date: July 1

For more information and application materials, please click here.

FUNDING OPPORTUNITY— Title Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4)

NIH is accepting applications for the "Title Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas" (RC4) (RFA-OD-10-005).

This program will support projects that address research endeavors in specific areas that will benefit from significant three-year funds without the expectation of continued NIH funding beyond this period. The research supported by the program should have high short-term impact, and a high likelihood of enabling growth and investment in biomedical research and development, public health, and health care delivery.

This FOA solicits applications proposing to develop and implement critical research innovations in one or more of the following five thematic areas:

  1. Applying Genomics and Other High Throughput Technologies
  2. Translating Basic Science Discoveries into New and Better Treatments
  3. Using Science to Enable Health Care Reform
  4. Focusing on Global Health
  5. Reinvigorating the Biomedical Research Community

Only applications for projects that require $500,000 or more in total costs per year are expected to be considered for funding.

LOI Deadline: February 15 (requested, not required)
Proposal Deadline: March 15

For details, please click here.

Case CCC Leadership would like to review potential responses, and can assist in developing themes as responsive to the RFA.


**All events are open to anyone interested in attending

January 11

Physiology & Biophysics Seminar
Robert Schleimer, PhD
Professor, Medicine
Chief, Allergy-Immunology
Northwestern University
Topic: Inflammation and Immune Responses in the Upper Airways and Sinuses of Humans
4:00 pm SOM E501

January 12

January 13

Neurosurgery Grand Rounds
Gene Barnett, MD
Professor, Neurological Surgery
Director, Brain Tumor Neuro-Oncology Center
CWRU/ Cleveland Clinic
Topic: Laser Interstitial Thermal Therapy of Brain Tumors
7:30 am JJ3-107 Cleveland Clinic

Grand Rounds
Lisa Arfons, MD
Fellow, Div. of Hem/Onc
Topic: T Cell Lymphomas
8:00 am Lerner B-151

January 14

Taussig Cancer Institute Core Curriculum Series
Ronald Sobecks, MD
Assistant Professor, Hematologic Oncology & Blood Disorders
CWRU/ Cleveland Clinic
Topic: Chronic Lymphocytic Leukemia
12:00 pm R3-002 Cleveland Clinic

Neurosciences Seminar
Jerry Silver, PhD
Professor, Neurosciences
Topic: New Insights into Axonal Dieback and Regeneration After Spinal Cord Injury
12:10 pm BRB 105

2nd Annual Nobel Symposium, Sponsored by the CWRU Cell Biology Program
Short talks describing the achievements of 2009 Nobel Laureates
Chemistry: William Merrick, PhD
Physiology or Medicine: Derek Taylor, PhD
Physics: Kathy Kash, PhD and Ken Singer, PhD
4:15 pm Rockefeller 301

January 15

Hem/Onc Fellows Seminar
Paolo Caimi, MD
Fellow, Div. of Hem/Onc
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Jayesh Mehta, MD
Professor, Medicine- Hem/Onc
Northwestern University
Topic: The Role of High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplant in Myeloma
8:00 am R3/002-003 Cleveland Clinic

Cell Biology Seminar
Ronald Conlon, PhD
Associate Professor, Genetics
Topic: TBA
10:00 am NC1-202 Cleveland Clinic

Cancer Center Seminar Series/ Blood Club
Brian Rini, MD
Associate Professor, Hematology & Medical Oncology
CWRU/Cleveland Clinic
Topic: Hypertension is a Biomarker for Clinical Outcome to VEGF-targeted Therapy
12:00 pm BRB 105

Genomics Medicine Institute
Yogen Saunthararajah, MD
Associate Professor, Hematologic Oncology & Blood Disorders
CWRU/ Cleveland Clinic
Topic: Differentiation-Context Enables Non-Cytoxic Epigenetic Treatment of Malignancy That Spares Normal Stem Cells
2:00 pm NE1-205 Cleveland Clinic

Cancer Center Research in Progress Seminar
Marvin Nieman, PhD
Instructor, Medicine- Hem/Onc
Topic: Interaction Between Protease Activated Receptors 1 and 4
4:00 pm WRB 3-136


For a complete listing of LRI seminars click here.


Case CCC Core Facility Fair
January 13
3:00 pm - 6:00 pm Wolstein Atrium and Auditorium

Case CCC Scientific Series- TREC
January 28
4:00 pm - 7:00 pm WRB 1-413
Stephanie Doerner, PhD
Cheryl Thompson, PhD
Ofer Reizes, PhD
Sanjay Patel, MD

Olof Pearson Lecture
February 5
12:00 pm WRB 1-413
Speaker: V. Craig Jordan, PhD
Scientific Director, Lombardi Cancer Center
Vincent T. Lombardi Chair of Translational Cancer Research
Georgetown University
Topic: Estrogen in the Life and Death of Breast Cancer

Case CCC Scientific Retreat
July 9-10
Location TBA


Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15
Scottsdale, AZ

AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Prospects for Personalized Prevention and Therapy
January 11-14
Loews Coronado Bay Resort, Coronado, CA

12th International Symposium on Anti-Angiogenic Agents: Angio 2010 Recent Advances and Future Directions in Basic and Clinical Cancer Research
February 4-6
Hyatt Regency La Jolla, San Diego, CA

AACR-JCA 8th Joint Conference on Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics
February 5-9
Hilton Waikoloa Village, Waikoloa, HI

13th Annual Meeting of the Translational Research Cancer Centers Consortium
March 1-2
Blackwell Inn, Columbus, OH

AACR 101st Annual Meeting
April 17-21
Washington, DC


Please mark your calendars for the next installment of the Case CCC Scientific Series and reception on January 28 from 4:00-7:00 pm in Wolstein Auditorium (WRB 1413). Presentations will be related to the Case Transdisciplinary Research on Energetics and Cancer (TREC) Center, led by Dr. Nathan Berger:

Stephanie Doerner: Diet, Obesity and Susceptibility to Colon Cancer

Cheryl Thompson, PhD: Activation of the PI3K pathway in colon and breast cancer

Ofer Reizes, PhD: Role of Leptin in Mammary Tumorigenesis

Sanjay Patel, MD: The Effect of Sleep Disturbances on Adipose Tissue Gene Expression

Everyone is welcome and encouraged to attend.


The December edition of the CTSC newsletter is now available. Please click here to view it.


We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!

FUNDING OPPORTUNITY– Damon Runyon Cancer Research Foundation Clinical Investigator Award

CWRU SOM has been invited to nominate up to three individuals for the Damon Runyon Cancer Research Foundation Clinical Investigator Award. This award supports young physician-scientists conducting patient-oriented cancer research, with a goal of increasing the number of physicians capable of moving seamlessly between the laboratory and the patient's bedside in search of breakthrough treatments.

If you are interested in applying for this award, please submit the following materials to gillian.irwin@case.edu by Wednesday, January 20: biosketch and a one-paragraph description of how your research fits the description of "Clinical Research" as described by the Damon Runyon Foundation.

Internal Deadline: January 20
External Deadline: March 1

For details, please click here.

FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (tracy.rehl@case.edu).

Click here to view the job description.


International Society for Stem Cell Research (ISSCR)
Deadline: January 14

Landon Foundation-AACR INNOVATOR Grant for Research in Personalized Cancer Medicine
Deadline: January 20

Landon Foundation-AACR INNOVATOR Award for Cancer Prevention Research
Deadline: January 20

Landon Foundation-AACR INNOVATOR Award for International Collaboration
Deadline: January 20

Prostate Cancer Foundation Creativity Awards
Deadline: January 31

IOTF Clinical Oncology Product Research/Review for Oncology Fellows
Deadline: January 31

IOTF Clinical Oncology Product Research/Review for Board Certified (BC) Oncologists
Deadline: January 31

ACS Ohio Division Joseph S. Silber Student Summer Fellowship
Deadline: February 3

Multiple Myeloma Research Foundation 2009 Seniors Award Program
Deadline: February 3

Leukemia Research Foundation Hollis Brownstein Research Grants Program
Deadline: February 15

AICR Investigator Initiated Grants
Deadline: February 19

AICR Matching Grants
Deadline: February 19

AICR Postdoctoral Awards
Deadline: February 19

IOTF Oncology Product Research/Review Fellows
Deadline: May 30

IOTF Cancer Prevention Fellows
Deadline: September 1

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Salary Limitation on Grants, Cooperative Agreements, and Contracts (NOT-OD-10-041)

Expiration of PAR-06-511, National Cancer Institute (NCI) Cancer Education and Career Development Program (R25) (NOT-CA-10-009)

SBIR Phase II Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics toward Commercialization (R44) (RFA-CA-10-009)

Recovery Act Limited Competition: NIH Basic Behavioral and Social Science Opportunity Network (OppNet) Short-term Mentored Career Development Awards in the Basic Behavioral and Social Sciences for Mid-career and Senior Investigators (K18) (RFA-OD-10-003)

NIH Support for Conferences and Scientific Meetings (Parent R13/U13) (PA-10-071)

Image-Guided Cancer Interventions (SBIR [R43/R44]) (PA-10-079)

Image-Guided Cancer Interventions (STTR [R41/R42]) (PA-10-080)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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