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Case Comprehensive Cancer Center Newsletter

September 14, 2009

MESSAGE FROM THE DIRECTOR– Cancer Center External Advisory Board Meeting

The Case CCC hosted the annual visit of its External Advisory Board last week. The advisors' comments are critical for planning and direction, and the Cancer Center leadership uses these visits to assist in evaluating how resources should be directed. Their comments are usually positive, instructive, and supportive, and are aimed at strengthening the scientific programs.

Presentations and discussions revolved around Cancer Center programs; Dr. Meropol also presented his vision for the clinical research program. The advisors were especially supportive of Cancer Center leadership, and pointed to many strong aspects of all of the scientific programs. Especially well received were the Cancer Genetics, Stem Cell and Hematologic Malignancies, Developmental Therapeutics, and Cancer Prevention and Control programs.

While the clinical trials program was not specifically reviewed in detail, its importance to the overall evaluation of the Cancer Center makes it a priority. The advisors strongly recommended that the Cancer Center focus on efforts to expand its joint trials activity and to increase accrual to clinical trials, with particular emphasis on minority recruitment.

A major recommendation emerging from the meeting is that the Cancer Center must increase its portfolio of multi-investigator grants. Thus, the pilot project support provided by the Cancer Center must be supplemented by other means to encourage these working groups to formulate applications. Several promising efforts are underway, and Cancer Center leadership continues its activities in support of developing the survivorship program, supporting the pilot program, and generating productive multi-investigator projects.

We will receive a full report from the EAB in the near future, which will be reviewed fully with the senior and program leadership.

Dr. Stan Gerson, MD
Director, Case CCC


NEW MEMBERS CORNER

Please join us in welcoming the following new members of the Case CCC:

Aaron Proweller, MD, PhD
Assistant Professor, Medicine- Cardiovascular Medicine
Molecular Basis of Cancer Program

Jeremy N. Rich, MD
Chairman and Staff, Stem Cell and Regenerative Medicine
Professor, CCLCM
Stem Cells and Hematologic Malignancies Program

Lisa R. Rogers, DO
Professor, Neurology
Clinical Program

Shuying Sun, PhD
Assistant Professor, General Medical Sciences- Oncology
Cancer Genetics Program


NCI CANCER BULLETIN

Featured Article
Study Questions Value of Prostate Cancer Screening

Cancer Research Highlights
Genetic Study Points to Potential Treatment for Melanoma

Chemotherapy Provides Longer Survival than Enzyme Therapy for Pancreatic Cancer

Denosumab Keeps Bones Strong during Prostate Cancer Treatment

Weight Lifting Reduces Lymphedema Symptoms after Breast Cancer

In West African Women, Majority of Breast Cancers Have a Poor Prognosis

Guest Director's Update: Dr. Rachel Ballard-Barbash
Finding the Right Mix of Care Providers for Cancer Patients

Commentary
A Conversation about Personal Genomic Tests with Dr. Muin Khoury


ASC OHIO DIVISION PILOT GRANT AND FELLOWSHIP PROGRAMS SUSPENDED

The Ohio Division Supported Research pilot grants program is suspended for fiscal year 2010 due to budget constraints. Also, Cancer Research Fellowships for clinicals are also under suspension for fiscal year 2010. Silber Fellowships are closed until January 2010.


FUNDING OPPORTUNUTY– Pezcoller-AACR International Award for Cancer Research

AACR is currently accepting applications for the 2010 Pezcoller-AACR International Award for Cancer Research. This annual award honors a scientist who has made a major scientific discovery in basic cancer research or who has made significant contributions to translational cancer research.

Nomination Deadline: September 15

For more information, please click here.


FUNDING OPPORTUNITY– AACR-Pancreatic Cancer Action Network

AACR and the Pancreatic Cancer Action Network have partnered to offer the following pancreatic cancer research funding opportunities. Proposed projects may be in any area of basic, translational, clinical or epidemiological cancer research, and must have direct application and relevance to pancreatic cancer.

Pancreatic Cancer Action Network-AACR Innovative Grants
LOI Deadline: October 5

Pancreatic Cancer Action Network-AACR Career Development Awards
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Research Fellowship
Application Deadline: October 28


FUNDING OPPORTUNITY– ACS Postdoctoral Fellowships

ACS is accepting applications for Postdoctoral Fellowships. These awards support the training of researchers who have received a doctoral degree to provide initial funding leading to an independent career in cancer research (including basic, preclinical, clinical, cancer control, psychosocial, behavioral, epidemiology, health services and health policy research).

Deadline: October 15

For more information, please click here.


FUNDING OPPORTUNITY– Acceleration Grant Opportunities in Cellular Molecular Imaging of Cancer, Cancer Biology, Therapeutics

Acceleration funding is available for investigative interdisciplinary teams with broad expertise in cancer biology, molecular imaging/imaging, pharmacology, genetics for opportunities to explore aspects of cancer biology with non-invasive imaging technologies.

This funding is designed to specifically provide the resources to fully develop ongoing projects for inclusion in ICMIC application, and is open to eligible faculty members with cancer focused funded research

Selected projects that will be used as the basis for a Summer 2010 P50 In-vivo Cellular and Molecular Imaging Center (ICMIC) grant and other future independent grants.

Deadline: September 15

Contact Marianne Sperk at Marianne.sperk@case.edu for more information and application instructions.


MARK YOUR CALENDARS– Case Center for Proteomics and Bioinformatics Symposium

The Center for Proteomics and Bioinformatics is proud to present the symposium, "Understanding Protein Complexes, Networks and the Interactome", on Monday, October 19. This event will be held in the Wolstein Research Building Auditorium 1-413. For this symposium, the Center has invited speakers from distinguished institutions to discuss current developments and applications of computational and wet-lab approaches toward interactome mapping.

Further information on the symposium program schedule will be available within the next few weeks. Registration is free. To register, please send your name and institution/department to CPB-Registration@case.edu.


MARK YOUR CALENDARS– 2009 Case CCC Breast Cancer Retreat

The Case Comprehensive Cancer Center is planning a one-day Breast Cancer Research Retreat for October 5 at the Sheep Barn, and is inviting all members of the Cancer Center community to attend.

Please contact Retreat Co-Directors, Ruth Keri, PhD or Mark Jackson, PhD with any questions.

If you are interested in attending but have not yet registered, please email Gillian Irwin Todd gillian.irwin@case.edu ASAP.

EVENTS

**All events are open to anyone interested in attending

September 14

Hem/Onc Research in Progress Seminar
Mathew Lesniewski, PhD
Postdoc, Laughlin lab, Div. of Hem/Onc
CWRU/ UH
Topic: BACH2 Regulates Foxp3 Expression in Umbilical Cord Blood (UCB) CD4+/45RA+ T-cells
12:00 pm WRB 2-136


September 15

Immunology Seminar Series
Cliff Harding, MD, PhD
Professor, Pathology
CWRU/ UH
Topic: Regulation of APC Function by Mycobacterium Tuberculosis Lipoproteins and Their Interactions with TLR2
12:00 pm WRB 1-413

Taussig Cancer Institute Core Curriculum Series
Ronald Sobecks, MD
Assistant Professor, Hematologic Oncology & Blood Disorders
CWRU/ Cleveland Clinic
Topic: Chronic Lymphocytic Leukemia
12:00 pm R3-002 Cleveland Clinic


September 16

Developmental Therapeutics Program Meeting cancelled

Grand Rounds
Matthew Cooney, MD
Assistant Professor, Medicine-Hematology/Oncology
CWRU/ UH
Topic: Novel Therapies for Prostate Cancer
8:00 am Lerner Tower B-151

Pathology Graduate Student Seminar
Yeritza Hernandez
Graduate Student, Boom Lab, Pathology
Topic: Differences in the Induction of Th-17/ Treg Cells Between Spleen and Lung APCs
12:00 pm WRB 1-413


September 17

Taussig Cancer Center Core Curriculum Series
Mikkael Sekeres, MD, MS
Associate Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: MDS
12:00 pm R3-002 Cleveland Clinic

Neurosciences Seminar Series
Gemma Casadesus, PhD
Instructor, Neurosciences
CWRU
Topic: Beyond Estrogen: The Role of Gonadotropins/GnRH on Cognition and AD
12:10 pm BRB 105

CSCRM and Bioethics Seminar/ Luncheon
M. William Lensch, PhD
Children's Hospital Boston, Dept. of Medicine- Hem/Onc
Harvard Medical School, Dept. of Pediatrics
Harvard Stem Cell Institute
Topic: Pluripotent Stem Cells and Human Disease Modeling
12:30 pm WRB 2-136


September 18

Hematology/ Oncology Fellows Seminar
Alvin Schmaier, MD
Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Thrombotic Disorders
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Katherine Hauser, MD
Fellow
Cleveland Clinic
Topic: Vitamin D Levels in Cancer Patients: Insufficient Screening and Supplementation
8:00 am R3-002/003 Cleveland Clinic

Genomic Medicine Institute
Sudha Iyengar, PhD
Professor, Epidemiology & Biostatistics
CWRU
Topic: From GWAS to the Casual Variant: Perspectives from Studies of Age-Related Macular Degeneration
2:00 pm NE1-205 Cleveland Clinic

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Paradigms in Lymphoma Management: A Case Based Approach
September 25
Marriott Downtown Cleveland at Key Center

Oscar D. Ratnoff Symposium
October 2
8:30 am – 5:00 pm WRB 1-413
Details

Breast Cancer Retreat
October 5
Sheep Barn, Squire Valleevue Farm

Case CCC Scientific Series
November 5 (please note change of date)
4:00 pm - 6:00 pm WRB 1-413


ADDITIONAL UPCOMING SEMINARS & EVENTS

AACR Seminar: Frontiers in Basic Cancer Research
October 8-11
Boston, MA
Details

AACR Seminar: Advances in Breast Cancer Research
October 13-16
Hyatt Regency Mission Bay Spa and Marina, San Diego, CA
Details

International Association for Comparative Research on Leukemia and Related Diseases (IACRLRD) Symposium XXIV
October 14-16
Ohio State University Comprehensive Cancer Center, Columbus, OH
Details

ICMS-AACR-INCa Fifth International Conference on Tumor Microenvironment: Progression, Therapy and Prevention
October 20-24
Palais des Congres de Versailles, Versailles, France
Details

AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
November 15-19 John B. Hynes Veterans Memorial Convention Center, Boston, MA Details

AACR Seminar: Frontiers in Cancer Prevention Research
December 6-9
Houston, TX
Details

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, AZ
Details

AACR Eighth Annual International Conference on Frontiers in Cancer Prevention Research
December 6-9
Hilton Americas, Houston, TX
Details

32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium
December 10-13
Henry B. Gonzalez Convention Center, San Antonio, TX
Details

AACR Seminar: Genetics and Biology of Brain Cancers
December 13-15
Omni San Diego Hotel, San Diego, CA
Details

AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Prospects for Personalized Prevention and Therapy
January 11-14, 2010
Loews Coronado Bay Resort, Coronado, CA
Details

AACR-JCA 8th Joint Conference on Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics
February 5-9, 2010
Hilton Waikoloa Village, Waikoloa, HI
Details

AACR 101st Annual Meeting
April 17-21, 2010
Washington, DC
Details



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

William Lawrence & Blanche Hughes Foundation
Deadline: September 16

2010 Szent-Györgyi Prize for Progress in Cancer Research
Deadline: September 30

Komen Postdoctoral Fellowship Research (PDF) Grants
Pre-Application Deadline: October 1
Full Application Deadline: November 17

Komen Post-Baccalaureate Training in Disparities Research (PBT-DR) Grants
Pre-Application Deadline: October 1
Full Application Deadline: November 17

ASCO Advanced Clinical Research Award (ACRA)
Full Application Deadline: October 1

World Cancer Research Fund International
Deadline: October 5

Clinical Investigator Development Program
Application Deadline: October 15

NIH Director's Pioneer Awards
Deadline: October 20

Clinical Research Scholar Career Development Training Program
Deadline: October 23

NIH Director's New Innovator Awards
Deadline: October 27

ED Thomas Post Doctoral Fellowship 2009
Deadline: November 2

Komen Postdoctoral Fellowship Research (PDF) Grants
Full Application Deadline: November 17

Komen Post-Baccalaureate Training in Disparities Research (PBT-DR) Grants
Full Application Deadline: November 17

DOD Lung Cancer Research Program Clinical Fellow Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3


DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD OCRP Ovarian Cancer Academy Dean Award
Proposal Deadline: December 2

ASCO Improving Cancer Care Grant Improving Cancer Care Grant (ICCG)
Full Application Deadline: December 3

DOD Lung Cancer Research Program Clinical Fellow Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Application Deadline: December 3

DOD PRCRP Synergistic Idea Awards
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Proposal Deadline: December 9

DOD PRCRP New Investigator Awards
Proposal Deadline: December 9

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Correction to Required Components for the 2010 NIH Directors Pioneer Award Program (DP1); RFA-RM-09-010 (NOT-RM-09-018)

Correction to Required Components for the 2010 NIH Directors New Innovator Award Program (DP2); RFA-RM-09-011 (NOT-RM-09-019)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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