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Case Comprehensive Cancer Center Newsletter

August 31, 2009

MESSAGE FROM THE DIRECTOR– Forward Thinking Interdisciplinary Alliance Investment Grants

Dear Members:

The Provost of CWRU has announced an internal competition for funds that relate to either the CWRU or SOM strategic plan to help promote development of programs and initiatives. The emphasis will be on those that link to the strategic elements put forth by the university and those that involve more than one school.

There is a requirement to have matching funds from the participating schools. The SOM is requesting all interested investigators submit a send a request for matching funds to Bob Miller (rhm3@case.edu) - no later than September 8. The request should include a half-page abstract of your proposal, list of participating faculty and schools, the approximate total budget, and what portion of the budget will need to be matched by the SOM.

The Cancer Center would like respond to this opportunity. A bit of creativity and compelling impact will help move proposals to the next rounds, given the clear breadth of priorities and interests on the part of the review committees.

Please consider submitting a response, review with your team, and forward to me so that the Cancer Center leadership can support and comment on your proposed submission. We will not delay your submission to the SOM, and if you would like to submit it directly through another school just let us know!

To view the RFP, please click here. To view the list of Alliances with SOM faculty highlighted, please click here.

Send along your topics and proposals to me at slg5@case.edu.

Good luck!

Stan Gerson, MD
Director, Case CCC


CASE CCC IN THE NEWS

Key Factor That Stimulates Brain Cancer Cells To Spread Identified
Science Daily (press release) - Aug 19, 2009
The study's senior author is Susann Brady-Kalnay, Ph.D., a neuroscientist at Case Western Reserve University in Cleveland and an expert on ...

Abnormal Protein May Signal Pancreatic Cancer
U.S. News & World Report - Aug 18, 2009
...Preventing the binding of prion to filamin A may open new avenues for therapeutic intervention of this deadly disease," study co-author Man-Sun Sy, professor of pathology, said in a university news release.

Cleveland: NE Ohio Stem Cell Research is Cutting Edge
WKYC-TV - Michael O'Mara - Aug 18, 2009
"Well, people really listen to us, nationwide and worldwide, frankly," said Dr. Stanton Gerson, Director of the UH Ireland Cancer Center and also Director ...Cleveland stem cell pioneers, like Dr. Arnold Caplan, have been leading the way in the cutting-edge adult stem cell research for 20 years. ...

First, Cure Cancer. Second, Build an iPhone App
MedCity News - Chris Seper - Aug 18, 2009
... said (Susann) Brady-Kalnay, an associate professor in the molecular biology and microbiology department at Case Western Reserve University... Her research will be online Tuesday at Cancer Research. The study's first author was Case graduate student Adam Burgoyne, and also included neurosurgeons Dr. Shenandoah Robinson and Dr. Andrew E. Sloan, and Robert H Miller, an authority on glial cell development.

System is Breath of Clean Air at Cleveland Clinic
Akron Beacon Journal - Cheryl Powell - Aug 10, 2009
... bone marrow transplants, said Dr. Brian Bolwell, chairman of the Cleveland Clinic's Department of Hematologic Oncology and the Taussig Cancer Institute...

Grapefruit Juice Can Juice up a Cancer Drug, Researchers Say
Kansas City Star - Vanessa Mcmains - Aug 8, 2009
Brian Rini of the Cleveland Clinic Taussig Cancer Institute cautioned people against thinking of grapefruit juice as an all-purpose booster. ...


FUNDING OPPORTUNITY– DOD OCRP Ovarian Cancer Academy Dean Award

The OCRP Ovarian Cancer Academy Dean Award supports visionary individuals who are established ovarian cancer researchers with a strong record of mentoring and a commitment to leadership. In addition to leading the Ovarian Cancer Academy, the Academy Dean will be recognized with the life-long title of Department of Defense (DOD) Ovarian Cancer Research Professorship.

Pre-Application Deadline: September 9
Proposal Deadline: December 2

For more information, please click here.

EVENTS

**All events are open to anyone interested in attending

August 31

Genomic Medicine Institute
Hippokratis Kiaris, PhD
Assistant Professor, Biochemistry
University of Athens, Greece
Topic: Heterotypic Interactions Between Cancer Cells and Stromal Fibroblasts in Carcinogenesis
2:00 pm NE1-205 Cleveland Clinic


September 1

Cancer Biology Seminar
Jaroslaw Maciejewski, MD, PhD
Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: Genomics of Myeloid Malignancies
11:00 am Cleveland Clinic NC1-202


September 2

Grand Rounds
Deepjot Singh, MD
Assistant Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Overview of Pancreatic Cancer, and Hepatobiliary Malignancies
8:00 am Lerner Tower B-151


September 3


September 4

Hematology/ Oncology Fellows Seminar
Afshin Dowlati, MD
Associate Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: How to Effectively Interpret the Medical Literature and Statistics
8:00 am Wearn 137

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Management of Lung Cancer in the Emphysema Patient: From Surgery to Cyberknife and Beyond
September 11
Embassy Suites, Independence

Paradigms in Lymphoma Management: A Case Based Approach
September 25
Marriott Downtown Cleveland at Key Center

Breast Cancer Retreat
October 5
Sheep Barn, Squire Valleevue Farm

Case CCC Scientific Series
October 8
4:00 pm - 6:00 pm WRB 1-413

**For more information on these symposiums, please contact Christine Rhoads.


ADDITIONAL UPCOMING SEMINARS & EVENTS

ASCO Breast Cancer Symposium
October 8-10
San Francisco Marriott
San Francisco, CA
Details

International Association for Comparative Research on Leukemia and Related Diseases (IACRLRD) Symposium XXIV
October 14-16
Ohio State University Comprehensive Cancer Center
Details

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, Arizona
Details


CORE FACILITY SURVEYS

Please help us to strengthen the Shared Resources of the Case Comprehensive Cancer Center by completing a survey. Your feedback on the core facilities that you have used will guide us in determining how the cores can be strengthened and what further investments should be made. Your input will help to ensure that the Cancer Center continues to meet the research needs of its members. To take the survey, please click here.

We are also requesting members complete a separate survey about the Laser Capture Microdissection Service of the Case Comprehensive Cancer Center. Please click here to take that survey.


FUNDING OPPORTUNITY– NIH Director's Pioneer, New Innovator, and Transformative R01 Initiatives

NIH welcomes proposals for 2010 NIH Director's Pioneer Awards and New Innovator Awards. Both programs are part of the NIH Roadmap for Medical Research and support exceptionally creative scientists who take highly innovative, potentially high-impact approaches to major challenges in biomedical or behavioral research.

Pioneer Awards provide up to $2.5 million in direct costs over 5 years and are open to scientists at any career stage.

New Innovator Awards provide up to $1.5 million in direct costs over the same period and are for early stage investigators (ESI) who have not received an NIH regular research (R01) or similar NIH grant.

NIH expects to make at least 7 Pioneer Awards and at least 33 New Innovator Awards in September 2010.

To continue its strong record of diversity in these programs, NIH especially encourages women and members of groups that are underrepresented in NIH research to apply.

Pioneer Award deadline: October 20.

New Innovator Award Deadline: October 27.

The Transformative R01 (T-R01) supports exceptionally innovative, high risk, original and/or unconventional research projects that have the potential to create or overturn fundamental paradigms. Please click here for more information about the program and upcoming funding opportunities.


FUNDING OPPORTUNITY– Clinical Investigator Development Program

The Center for Cancer Research (CCR) announces a training opportunity for physicians interested in dedicating their careers to clinical oncology research. The Clinical Investigator Development Program will link eligible clinicians to a vibrant, multidisciplinary research community of more than 250 talented CCR intramural scientists conducting cutting-edge research on the campuses of the National Institutes of Health (NIH) in Bethesda and Frederick, Maryland. The CCR is nationally recognized as a premier training ground for clinical research, which is conducted in the state-of-the-art Clinical Research Center.

Application Deadline: October 15

Please click here for more information.


FUNDING OPPORTUNITY– Acceleration Grant Opportunities in Cellular Molecular Imaging of Cancer, Cancer Biology, Therapeutics

Acceleration funding is available for investigative interdisciplinary teams with broad expertise in cancer biology, molecular imaging/imaging, pharmacology, genetics for opportunities to explore aspects of cancer biology with non-invasive imaging technologies.

This funding is designed to specifically provide the resources to fully develop ongoing projects for inclusion in ICMIC application, and is open to eligible faculty members with cancer focused funded research

Selected projects that will be used as the basis for a Summer 2010 P50 In-vivo Cellular and Molecular Imaging Center (ICMIC) grant and other future independent grants.

Deadline: September 15

Contact Marianne Sperk at Marianne.sperk@case.edu for more information and application instructions.



FUNDING OPPORTUNITY– 2010 Szent-Györgyi Prize for Progress in Cancer Research

The National Foundation for Cancer Research is accepting nominations for the 2010 Szent-Györgyi Prize for Progress in Cancer Research. This annual prize, which includes a $25,000 cash award, is presented to a distinguished individual who has helped advance the field of cancer research and whose basic science research accomplishments have helped improve treatment options for patients. Recipients will be recognized and featured in major public media and press, national Prize designations, and ceremonies of the National Foundation for Cancer Research, an international charity supported by more than 4 million donors including hundreds of private foundations and corporations.

Deadline: September 30

For more information, please click here.


MARK YOUR CALENDARS– Circulating Tumor Cells (CTCs): Emerging Technologies for Detection, Diagnosis and Treatment

The Division of Cancer Treatment and Diagnosis, the Small Business Innovation Research Office and the Division of Cancer Prevention invite you to attend, Circulating Tumor Cells: Emerging Technologies for Detection, Diagnostics and Treatment", to be held on September 10-11 on the NIH campus in Bethesda, Maryland.

The aim of the meeting is to facilitate new scientific collaborations and interactions, and to build new research programs in this emerging field in order to promote the translation of basic research to clinical applications and product development. There will also be discussions about funding opportunities for CTC research.

There is no registration fee; registration deadline: September 7.

For details, please click here.


MARK YOUR CALENDARS– Case Center for Proteomics and Bioinformatics Symposium

The Center for Proteomics and Bioinformatics is proud to present the symposium, "Understanding Protein Complexes, Networks and the Interactome", on Monday, October 19. This event will be held in the Wolstein Research Building Auditorium 1413. For this symposium, the Center has invited speakers from distinguished institutions to discuss current developments and applications of computational and wet-lab approaches toward interactome mapping.

Further information on the symposium program schedule will be available within the next few weeks. Registration is free. To register, please send your name and institution/department to CPB-Registration@case.edu.


MARK YOUR CALENDARS– 2009 Case CCC Breast Cancer Retreat

The Case Comprehensive Cancer Center is planning a one-day Breast Cancer Research Retreat for October 5 at the Sheep Barn, and is inviting all members of the Cancer Center community to attend.

Please contact Retreat Co-Directors, Ruth Keri, PhD or Mark Jackson, PhD with any questions.

If you are interested in attending but have not yet registered, please email Gillian Irwin Todd (gillian.irwin@case.edu) ASAP.


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

International Myeloma Foundation 2010 Brian D. Novis Junior Research Award
Deadline: August 31

PhRMA Foundation Pharmacology/Toxicology
Pre Doctoral Fellowship
Post Doctoral Fellowship
Sabbatical Fellowship
Research Starter Grant
Deadline: September 1

PhRMA Foundation Informatics
Pre Doctoral Fellowship
Post Doctoral Fellowship
Sabbatical Fellowship
Research Starter Grant
Deadline: September 1

ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure
LOI Deadline: September 1

ASCO Improving Cancer Care Grant Improving Cancer Care Grant (ICCG)
LOI Deadline: September 1
Full Application Deadline: December 3

DOD Lung Cancer Research Program Concept Award
Pre-Application Deadline: August 20
Application Deadline: September 3

International Myeloma Foundation 2010 Brian D. Novis Senior Research Award
Deadline: September 4

ASCO Career Development Award
Full Application Deadline: September 9

ASCO Young Investigator Award
Application Deadline: September 9

William Lawrence & Blanche Hughes Foundation
Deadline: September 16

ASCO Advanced Clinical Research Award (ACRA)
Full Application Deadline: October 1

World Cancer Research Fund International
Deadline: October 5

Clinical Research Scholar Career Development Training Program
Deadline: October 23

ED Thomas Post Doctoral Fellowship 2009
Deadline: November 2


DOD Lung Cancer Research Program Clinical Fellow Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

ASCO Improving Cancer Care Grant Improving Cancer Care Grant (ICCG)
Full Application Deadline: December 3

DOD Lung Cancer Research Program Clinical Fellow Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Application Deadline: December 3

DOD PRCRP Synergistic Idea Awards
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Proposal Deadline: December 9

DOD PRCRP New Investigator Awards
Proposal Deadline: December 9

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Contact Changes for RFA-OD-09-001: Dietary Supplement Research Centers: Botanicals (P50)(NOT-OD-09-143)

Pre-application Meeting for Requests-for-Applications (RFAs) for the Early Detection Research Network (EDRN) (RFA-CA-09-017, CA-09-018, CA-09-019, and CA-09-020) (NOT-CA-09-033)

Exploratory Innovations in Biomedical Computational Science and Technology (R21) (PAR-09-219)

Exploratory Studies in Cancer Detection, Diagnosis, and Prognosis (R21) (PA-08-267)

Quick-Trials for Imaging and Image-Guided Interventions: Exploratory Grants (R21) (PAR-08-147)

Understanding the Effects of Emerging Cellular, Molecular, and Genomic Technologies on Cancer Health Care Delivery(R01) (PA-09-004)

Understanding the Effects of Emerging Cellular, Molecular, and Genomic Technologies on Cancer Health Care Delivery (R21) (PA-09-005)

Clarification of Specific Research Objective in PAR-09-224, Improving Diet and Physical Activity Assessment (R01) (NOT-CA-09-032)

Extension of Expiration Date for PAR-06-511: National Cancer Institute (NCI) Cancer Education and Career Development Program (R25) (NOT-CA-09-034)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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