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Case Comprehensive Cancer Center Newsletter

July 6, 2009

MESSAGE FROM THE DIRECTOR– Case Comprehensive Cancer Center Annual Scientific Retreat, July 10-11, 2009, Bertram Inn, Aurora

This year's scientific retreat brings together Cancer Center scientific and clinical research programs at a new site, the Bertram Inn in Aurora, Ohio.

The retreat will emphasize topics of great interest to members, including recent stem cell biology, disease-based initiatives in breast, brain cancers and melanoma, and new scientific efforts in angiogenesis, high throughput sequencing, and drug discovery.

Since many of these topics cut across scientific programs, this year we have emphasized the science and not the programs, in an effort to promote interprogrammatic efforts. We will also review the current RFA for survivorship research, will announce the new RFA in biorepository-based research, and review the newest advances in technology available through our shared resources.

In addition, we will have introductory presentations by two recent senior recruits to the institutions: Dr. Neal Meropol, Associate Director of Clinical Research, and Dr. Mitch Machtay, Chair of Radiation Oncology at UH, who will develop a translational program in radiation biology and treatments.

Our special guest speaker is Dr. Milton Brown, who runs the drug discovery program at the Lombardi Comprehensive Cancer Center at Georgetown University. He has been asked to help us develop our drug discovery effort.

Overall, more than 55 members have helped organize the retreat and are presenting! This should be a terrific review of progress, a wonderful opportunity to update yourself about recent scientific advances, and a time to consider new collaborations. Further, this is the retreat that will help us frame priorities in the year prior to the renewal application for our core grant.

Thank you for attending and for your support of our cancer research efforts.

Stan Gerson, MD
Director, Case CCC


CASE CCC IN THE NEWS

Arteriocyte Medical Systems' Work Shows Promise Toward Developing ...
The Plain Dealer - cleveland.com - June 30, 2009
Artificially producing red blood cells -- if done successfully and safely -- has the potential to replace blood donations, said Dr. Alvin Schmaier, ...


GRANT SYSTEM SEEN AS "MAJOR IMPEDIMENT" TO TRANSFORMATIVE CANCER RESEARCH

ASCO Daily Cancer News

In a front-page story, the New York Times (6/28, A1, Kolata) reported that "the fight against cancer is going slower than most had hoped, with only small changes in the death rate in the almost 40 years since it began." Some scientists say "one major impediment...is the grant system itself," noting that "it has become a sort of jobs program, a way to keep research laboratories going year after year with the understanding that the focus will be on small projects unlikely to take significant steps toward curing cancer." These small projects are selected because projects "that could make a major difference in cancer prevention and treatment are all...too uncertain." Dr. Raynard S. Kington, acting director of the National Institutes of Health, said that top federal cancer officials "recognize that the system probably provides disincentives to funding really transformative research." In fact, "grant review committees" have "become more wary about giving scarce money to speculative proposals." Kington added, however, that NIH "has started 'pilot experiments' to see if there is a better way of getting financing for innovative projects."


FUNDING OPPORTUNITY– Nancy R. Gelman Foundation Breast Cancer Seed Grants

The Nancy R. Gelman Foundation has announced its 2009 Seed Grant Competition. These grants will fund projects aimed at improving outcomes for women with breast cancer by promoting global improvement in services provided to women with or at risk of breast cancer.

Deadline: August 5

For more information, please click here.


NCI CANCER BULLETIN

Featured Article
FDA Will Regulate Tobacco Under New Law

Cancer Research Highlights
For Children with Leukemia, Radiation May Be Unnecessary

Survivors of Hodgkin Lymphoma May Face Increased Risk of Stroke

Another Genetic Change Linked to Neuroblastoma: Missing DNA

Immune Cells with Stem Cell-like Properties Destroy Tumors in Mice

Director's Update
Putting Some Perspective on Research and Risk

Guest Commentary: Dr. Jeanette Vega
Chile and the United States–Forming a Proud Partnership


CALL FOR ABSTRACTS– 2009 Case CCC Breast Cancer Retreat

The Case Comprehensive Cancer Center is planning a one-day Breast Cancer Research Retreat for Monday, September 28, and is inviting all members of the Cancer Center community to attend.

The abstracts that are chosen will be incorporated into the agenda either by giving a short talk or presenting a poster.

We look forward to a stimulating and informative retreat.

Please contact Retreat Co-Directors, Ruth Keri, PhD or Mark Jackson, PhD with any questions.

Please send abstracts by August 1, 2009 via email to: Gillian Irwin.

EVENTS

**All events are open to anyone interested in attending

July 6


July 7


July 8

Grand Rounds
Henry Koon, MD
Assistant Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: The Evaluation and Treatment of Malignant Melanoma
8:00 am Lerner Tower B-151

Pathology Graduate Student Dissertation Defense
Sarah Swerdlow
Distelhorst Lab
CWRU/ UH
Topic: Glucocorticoid Induction of Autophagy in Lymphocytes, Mediated by DIG2 and mTOR Signaling
1:00 pm BRB 105

Cleveland Stem Cell Exhibit
3:30 pm WRB Atrium

CSCRM Seminar
Masakazu Ishikawa, MD, PhD
Case Cardiovascular Research Institute
Visiting Faculty, Regenerative Medicine
Hiroshima University Hospital, Japan
Topic: Cell-Assisted Therapy in Orthopaedic Field
4:30 pm WRB 1413


July 9

Neurological Institute Visiting Speaker
Andrew Parsa, MD, PhD
Associate Professor, Neurological Surgery
University of California, San Francisco
Topic: From Benchtop to Bedside: An Autologous HSP Vaccine Can Evoke a Tumor Specific Immune Response in Glioma Patients
2:00 pm Hanna House Conference Room 537


July 10

Case CCC Scientific Retreat
Bertram Inn and Conference Center, Aurora
Details


Hematology/ Oncology Fellows Seminar
Rick Creger, PharmD
CWRU/ UH
Topic: Supportive Pharmacotherapy
8:00 am Wearn 137

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Management of Lung Cancer in the Emphysema Patient: From Surgery to Cyberknife and Beyond
September 11
Embassy Suites, Independence

Paradigms in Lymphoma Management: A Case Based Approach
September 25
Marriott Downtown Cleveland at Key Center

Case CCC Scientific Series
October 8
4:00 pm - 6:00 pm WRB 1-413

**For more information on these symposiums, please contact Christine Rhoads.


ADDITIONAL UPCOMING SEMINARS & EVENTS

2nd Annual Business Education Course The Business of Regenerative Medicine: From Stem Cells to the Market Place
July 13-16
George S. Dively Building, CWRU Campus
Details

2009 caBIG® Annual Meeting: Solving Basic and Clinical Research Challenges in Cancer and Beyond
July 20 – 22
Marriott Wardman Park, Washington, DC
Details

VASCULATA Summer Course
July 28 - July 31
Cleveland Clinic Lerner Research Institute
Details

ACS Pan Ohio Hope Ride
July 30 - August 2
Details

MSC2009: The Regenerative Medicine and Adult Stem Cell Therapy Conference
August 17-19
Cleveland Marriott Downtown at Key Center
Details

ASCO Breast Cancer Symposium
October 8-10
San Francisco Marriott
San Francisco, CA
Details

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, Arizona
Details



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Doris Duke Charitable Foundation Innovation in Clinical Research Award Competition
Proposal Deadline: July 8

Bone Marrow Failure Hypothesis Development Awards (BMFRP)
Pre-Application Deadline: July 9
Application Deadline: July 30

National Breast Cancer Coalition Fund Advocacy in Action Grants
Deadline: July 10

NCRR Competitive Revision Application
Deadline: July 10

DOD PCRP Prostate Cancer Pathology Resource Network Award
Pre-Application Deadline: July 15
Proposal Deadline: August 5

DOD PRCRP Concept Awards
LOI Deadline: July 15
Proposal Deadline: July 30

Susan G. Komen for the Cure Promise Grants: Special Focus on Prevention
Deadline: July 15

Lustgarten Foundation
LOI Deadline: July 24
Application Deadline: August 7

Bone Marrow Failure Hypothesis Development Awards (BMFRP)
Application Deadline: July 30

Susan G. Komen for the Cure Investigator-Initiated Research (IIR) Grants
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst in Disparities Research (CCDR) Grants
Full Application Deadline: July 31

DOD PCRP Prostate Cancer Pathology Resource Network Award
Proposal Deadline: August 5

DOD PRCRP Synergistic Idea Awards
Pre-proposal Deadline: August 5
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Pre-proposal Deadline: August 5
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Pre-proposal Deadline: August 5
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Pre-proposal Deadline: August 5
Proposal Deadline: December 9


DOD PRCRP New Investigator Awards
Pre-proposal Deadline: August 5
Proposal Deadline: December 9

Lustgarten Foundation
Application Deadline: August 7

AACR–National Brain Tumor Society Fellowship, in memory of Bonnie Brooks
Deadline: August 10

Mesothelioma Applied Research Foundation
Deadline: August 15

Damon Runyon Cancer Research Foundation Fellowships
Deadline: August 17

International Myeloma Foundation 2010 Brian D. Novis Junior Research Award
Deadline: August 31

ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure
LOI Deadline: September 1

International Myeloma Foundation 2010 Brian D. Novis Senior Research Award
Deadline: September 4

William Lawrence & Blanche Hughes Foundation
Deadline: September 16

ED Thomas Post Doctoral Fellowship 2009
Deadline: November 2

DOD PRCRP Synergistic Idea Awards
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Proposal Deadline: December 9

DOD PRCRP New Investigator Awards
Proposal Deadline: December 9

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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