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Case Comprehensive Cancer Center Newsletter

June 22, 2009


New Therapy May Fight Prostate Cancer
WebMD - Jun 19, 2009
... but it is way too early to get excited," says Derek Raghavan, MD, PhD, who directs the Cleveland Clinic's Taussig Cancer Institute. ...

NIH Funds $9.5 Million for Research on HIV and the Human Innate Immune System
...Under the direction of lead investigator Aaron Weinberg, professor and chair of the Department of Biological Sciences at the dental school, a team of 22 researchers will unravel changes in the human body's innate immune system in HIV-infected people on antiretroviral therapies to provide new insights into how the body keeps us healthy...

Low-fat Diet Helps Genetically Predisposed Animals Avoid Liver Cancer
Science Daily (press release) - June 11, 2009
... humans," says senior co-author Joseph Nadeau, Professor and Chair of the Department of Genetics at Case Western Reserve University School of Medicine. ...Co-authors ...Nathan A. Berger,...from Case Western Reserve University.


The 2009 scientific retreat of the Cancer Center will be July 10-11, 2009 at the Bertram Inn and Conference Center in Aurora, Ohio. This annual gathering is always an important event for the Cancer Center, giving us an opportunity to exchange ideas, evaluate current initiatives, and reorient our development and scientific priorities as needed. This year's program was developed with the assistance of the Cancer Center Retreat Program Committee, whose members are Drs. Alex Almasan, Ruth Keri, Mary Step, and John Wang.

Our program committee recommended some new approaches to the development of the agenda; members noted that they wished to highlight the scientific interests of new members and learning more about specific attributes of the core facilities. Thus, scientific presentations will feature some new members, and include capabilities of the most relevant core facilities to the specific topic. Rather than the traditional program-based breakout sessions, this year will include special topics that encourage interprogrammatic participation around selected themes.

We hope you will stay in the area and enjoy some local attractions surrounding the Bertram Inn and Conference Center, including Wildwater Kingdom, Aurora Farms Premium Outlets, and Thorncreek Winery & Gardens. The Barrington Golf Club, a Jack Nicklaus Signature Course, is nearby, as well as Boulder Creek and Aurora Country Club. If you are interested in playing golf on Saturday afternoon, please indicate this when you register and we will inform the staff at the Bertram Inn who will assist in making these arrangements.

Hotel rooms have been reserved for retreat attendees, and there is no room fee. We encourage people to spend the night, as the Bertram Inn is at least a 40 minute drive from University Circle, and the program starts early. Please contact gillian.irwin@case.edu to request a room.

For details and to view the agenda, please click here.

FUNDING OPPORTUNITY– National Breast Cancer Coalition Fund Advocacy in Action Grants

National Breast Cancer Coalition Fund (NBCC) his currently accepting applications for Advocacy in Action Grants. These grants will be awarded in 2009, and have a potential for renewal in 2010. NBCC will award up to 20 grants to be used to expand public policy and advocacy work of NBCC in local communities. Applicants should specifically describe how they will use the funds to support the NBCC mission of ending breast cancer through research, access and influence. Winning organizations will be expected to further public policy and legislative priorities of NBCC, as well as advance their organization's grassroots advocacy in their local community. Current NBCC member groups that are 501 (c)(3) and/or 501(c)(4) organizations are eligible to apply.

Deadline: July 10

For more information, please click here.


VASCULATA is a national summer course that promotes the study of vascular biology, and will be held July 28 - July 31 at the Cleveland Clinic Lerner Research Institute. Sponsored by the Cleveland Clinic and North American Vascular Biology Organization (NAVBO), this workshop is designed to present an overview of the field and future areas of active research. New for 2009, VASCULATA is offering a practical workshop where students can learn technically challenging laboratory techniques. Individuals with little or no background in vascular biology are encouraged to attend, and current trainees in the field and all interested individuals are invited to participate. This includes students (undergraduates, graduate students, medical students), trainees (postdocs, research fellows, residents) and others (junior and senior faculty).

A great line up of world-renowned scientists will be presenting at VASCULATA this year. Speakers include Edward Plow (Keynote Speaker, CCF), Bela Anand-Apte (CCF), Tatiana Byzova (CCF), Paul DiCorleto (CCF), Maria Febbraio (CCF), Jorge Garcia (CCF), Gary Gibbons (Morehouse College of Medicine), Mukesh Jain (CWRU), Marc Penn (CCF), Eugene Podrez (CCF), Jeremy Rich (CCF), Brian Rini (CCF), Martin Schwartz (University of Virginia), Stephen Schwartz (University of Washington), Roy Silverstein (CCF), Michael Simons (Yale University), Olga Stenina (CCF), and Michiko Watanabe (CWRU).

Registration fees are inexpensive and vary depending on education level.

For details, please click here.


Featured News: Genetic Clue to Rare Ovarian Cancers Found

Treatment Regimen Extends Survival for Women with Cervical Cancer

Standard Treatment for Anal Cancer Confirmed

Donated Stem Cell Transplants Better than Self-transplants for Most Patients with AML

Restoring MicroRNA Expression Stops the Spread of Liver Cancer in Mice

Among the Elderly, Adverse Events from Colonoscopy Are Rare

Guest Director's Update: Dr. Bradford Wood
New Center Explores Imaging Technologies for Localized Cancer Treatments


**All events are open to anyone interested in attending

June 22

Research in Progress Seminar
Lachelle Weeks
Graduate Student, Liu Lab
Div. of Hem/Onc
Topic: The Impact of DNA Damage Induced Disruption of Base Excision Repair Homeostasis
12:00 pm WRB 2-136

June 23

Taussig Cancer Institute Core Curriculum Series
Brian Hill, MD
Taussig Cancer Institute
Cleveland Clinic
Topic: Growth Factors
12:00 pm R3-002 Cleveland Clinic

June 24

Grand Rounds
Tanyanika Phillips-Towe, MD
Assistant Professor, Medicine- Hem/Onc
Topic: Changing Health Care Practice for Older Adults with Late Stage Non-small Cell Lung Cancer: Achieving Personalized Cancer Care in an Aging Nation
8:00 am Lerner Tower B-151

June 25

Taussig Cancer Institute Core Curriculum Series
Jenny Kim, MD
Taussig Cancer Institute
Cleveland Clinic
Topic: TBA
12:00 pm R3-002 Cleveland Clinic

June 26

Hematology/ Oncology Fellows Seminar
Paolo Caimi, MD
Fellow, Div. of Hematology/ Oncology
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
John Wagner, MD
Professor, Pediatrics and Division Director, Hematology-Oncology and Blood and Marrow Transplantation Program
University of Minnesota
Topic: Umbilical Cord Blood in the Treatment of Malignant Disease
8:00 am R3/002-003 Cleveland Clinic


For a complete listing of LRI seminars click here.


ASCO Review
June 25
InterContinental Hotel

Case CCC Scientific Retreat 2009
July 10-11
Bertram Inn & Conference Center, Aurora

Management of Lung Cancer in the Emphysema Patient: From Surgery to Cyberknife and Beyond
September 11
Embassy Suites, Independence

Paradigms in Lymphoma Management: A Case Based Approach
September 25
Marriott Downtown Cleveland at Key Center

Case CCC Scientific Series
October 8
4:00 pm - 6:00 pm WRB 1-413

**For more information on these symposiums, please contact Christine Rhoads.


2nd Annual Business Education Course The Business of Regenerative Medicine: From Stem Cells to the Market Place
July 13-16
George S. Dively Building, CWRU Campus

2009 caBIG® Annual Meeting: Solving Basic and Clinical Research Challenges in Cancer and Beyond
July 20 – 22
Marriott Wardman Park, Washington, DC

ACS Pan Ohio Hope Ride
July 30 - August 2

MSC2009: The Regenerative Medicine and Adult Stem Cell Therapy Conference
August 17-19
Cleveland Marriott Downtown at Key Center

ASCO Breast Cancer Symposium
October 8-10
San Francisco Marriott
San Francisco, CA

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, Arizona

CALL FOR ABSTRACTS– 2009 Case CCC Breast Cancer Retreat

The Case Comprehensive Cancer Center is planning a one-day Breast Cancer Research Retreat for Monday, September 28, and is inviting all members of the Cancer Center community to attend.

The abstracts that are chosen will be incorporated into the agenda either by giving a short talk or presenting a poster.

We look forward to a stimulating and informative retreat.

Please contact Retreat Co-Directors, Ruth Keri, PhD or Mark Jackson, PhD with any questions.

Please send abstracts by August 1, 2009 via email to: Gillian Irwin.

FUNDING OPPORTUNITY– Susan G. Komen for the Cure Promise Grants: Special Focus on Prevention

Susan G. Komen for the Cure is accepting pre-applications for Prevention Promise Grants. These grants seek to support integrated programs of collaborative and cross-disciplinary research projects leading to the aggressive translation of scientific discoveries into interventions and strategies that have the greatest potential to significantly reduce breast cancer incidence, defined here in terms of the prevention of primary breast cancers in previously asymptomatic women or prevention of second primary breast cancers in women with a previous history of cancer. Proposals seeking to prevent breast cancer recurrence would not be within the scope of this RFA. These grants seek to remove current roadblocks to development and clinical translation of effective prevention interventions. Awards will provide up to $5million over 3-5 years.

Pre-application Deadline: July 15

For more information, please click here.

FUNDING OPPORTUNITY– International Myeloma Foundation 2010 Brian D. Novis Research Awards

The International Myeloma Foundation funds several research grants including the Brian D. Novis Research Award. These grants are provided through donations from private individuals, and are presented annually by the International Myeloma Foundation. These awards go to doctors/researchers doing work in the field of multiple myeloma. The Brian D. Novis Award honors the IMF's founder Brian Novis, who died of multiple myeloma in July of 1992. The International Myeloma Foundation is a non-profit organization whose mission is to improve the quality of life for myeloma patients while working toward prevention and a cure.

Junior Research Award
Candidates for this award will have completed postdoctoral studies or clinical fellowships not later than August 1 of the application year. They also must be able to devote a minimum of 50% of his or her time to the research project during the award year, and have the ability to provide a completed application with evidence of a meritorious research project.
Deadline: August 31

Senior Research Award
These awards are targeted to established investigators with a track record in myeloma or related research, and are designed for projects which represent a different focus, direction or area of research from those in which they are currently funded. In most cases, these awards will be for pilot projects to obtain sufficient funding for larger applications from NIH or similar larger funding agencies.
Deadline: September 4


Clinical and Translational Science Collaborative (CTSC) Pilot Funds
Deadline: July 1
CWRU, UH, MetroHealth
Cleveland Clinic

Doris Duke Charitable Foundation Innovation in Clinical Research Award Competition
Proposal Deadline: July 8

Bone Marrow Failure Hypothesis Development Awards (BMFRP)
Pre-Application Deadline: July 9
Application Deadline: July 30

NCRR Competitive Revision Application
Deadline: July 10

DOD PCRP Prostate Cancer Pathology Resource Network Award
Pre-Application Deadline: July 15
Proposal Deadline: August 5

Lustgarten Foundation
LOI Deadline: July 24
Application Deadline: August 7

Bone Marrow Failure Hypothesis Development Awards (BMFRP)
Application Deadline: July 30

Susan G. Komen for the Cure Investigator-Initiated Research (IIR) Grants
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst in Disparities Research (CCDR) Grants
Full Application Deadline: July 31

DOD PCRP Prostate Cancer Pathology Resource Network Award
Proposal Deadline: August 5

Lustgarten Foundation
Application Deadline: August 7

Mesothelioma Applied Research Foundation
Deadline: August 15

Damon Runyon Cancer Research Foundation Fellowships
Deadline: August 17

ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure
LOI Deadline: September 1

William Lawrence & Blanche Hughes Foundation
Deadline: September 16

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Pilot studies in Pancreatic Cancer (R03) (PA-08-209)

Pilot studies in Pancreatic Cancer (R21) (PA-08-208)

Translational Research at the Aging/Cancer Interface (TRACI) (R21) (PA-08-231)

Diet-Induced Changes in Inflammation as Determinants of Colon Cancer (R01) (PA-08-210)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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