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June 15, 2009 |
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MESSAGE FROM THE DIRECTORDear Cancer Center Members: Our program committee recommended some new approaches to the development of the agenda; members noted that they wished to highlight the scientific interests of new members and learning more about specific attributes of the core facilities. Thus, scientific presentations will feature some new members, and include capabilities of the most relevant core facilities to the specific topic. Rather than the traditional program-based breakout sessions, this year will include special topics that encourage interprogrammatic participation around selected themes. The retreat will be anchored by a keynote address on drug discovery delivered by Milton Brown, MD, PhD. Dr. Brown is the Director of the Drug Discovery Program and the Edwin H. Richard and Elisabeth Richard von Matsch Endowed Chair in Experimental Therapeutics at Georgetown University. He is a medicinal chemist with a major interest in the design, synthesis, and evaluation of new drugs. He is also program leader for the Lombardi Comprehensive Cancer Center's Drug Discovery and Developmental Therapeutics Program. Dr. Brown's laboratory has evaluated over 1000 compounds for possible use as therapeutics to treat prostate cancer, leukemia, and epilepsy. The breakout sessions will follow Dr. Brown's presentation, and Dr. Brown will participate in the session that will continue to explore topics of interest in drug development and discovery. Program leaders are encouraged to review the proposed topics and in turn note those of particular interest to their program themes and members. Our emphasis on multi-investigator efforts and disease based initiatives will continue with presentations and discussions on lung cancer and melanoma, and will bring the membership up to date on activities and developments in support of our survivorship initiative. Dinner on Friday evening will be preceded by core facility poster presentations accompanied by beer, wine, and cocktails to ease the transition to social activities for the remainder of the evening. While we have elected not to have a formal scientific presentation after dinner, this would be an ideal time for small group discussions. At the core facility poster session, we will also present the new large equipment coming into the Cancer Center through large instrumentation grants, institutional resources, cancer center commitments, and Howard Hughes Medical Institute. Among these items are: Solexa (high throughput sequencing), Amnis Image Stream Analyzer in Cytometry, Fluorescence Micro Tomography equipment in the Imaging Core, Upgrade ABI TaqMan Based Genotyping and the Gene Titan Affymetrix Analysis equipment in Gene Expression and Genotyping Core, and Veridex (Immunicon) equipment at Taussig. Saturday morning, the program will focus on transdisciplinary research efforts. We will open with presentations on topics related to the Cancer Prevention, Control and Population Research and Aging-Cancer Research Programs, including Survivorship. Our retreat will conclude with presentations from our newest recruits: Neal Meropol, MD as Associate Director for Clinical Research at the Case CCC, and Mitchell Machtay, MD, as Chair of Radiation Oncology at CWRU and UHCMC. After dismissal of the general, group, Cancer Center senior leadership and program leaders will meet to assess priorities, plan new initiatives, and to allocate funds for new pilot grant RFAs and core facility equipment purchases. Their discussions will begin the pre-renewal assessment of individual programs, which will come in useful in the spring of 2010 when the Cancer Center will begin the process of assembling our competitive renewal, which is due mid-2011. The retreat will end after lunch, and we hope you will stay in the area and enjoy some local attractions surrounding the Bertram Inn and Conference Center, including Wildwater Kingdom, Aurora Farms Premium Outlets, and Thorncreek Winery & Gardens. The Barrington Golf Club, a Jack Nicklaus Signature Course, is nearby, as well as Boulder Creek and Aurora Country Club. If you are interested in playing golf on Saturday afternoon, please indicate this when you register and we will inform the staff at the Bertram Inn who will assist in making these arrangements. Please fill out the Registration Form and let us know whether or not you are able to attend. Please return the form to gillian.irwin@case.edu as soon as possible so we can plan rooms for the break out sessions and plan meets and rooms. Thank you for the time commitment that you have already made to the Cancer Center. If you would like to add a topic to the list of presentations, have a comment about the schedule of events, or would like to provide input, please email me at slg5@case.edu. I want to thank you in advance for taking the time out of your busy schedules to participate in this important event and showing your support for the Cancer Center. I look forward to seeing you on July 10-11. Stan Gerson, MD CASE CCC IN THE NEWSLow-fat Diet Helps Genetically Predisposed Animals Avoid Liver Cancer NEW MEMBERS CORNERPlease join us in welcoming the following new members of the Case CCC: MARK YOUR CALENDARS– Drug Discovery and Developmental Therapeutics RetreatJoin your colleagues on Saturday, June 20 from 8:30 am - 1:00 pm at the Squire Valleevue Farm Sheep Barn for a broad scientific discussion of new drug targets, screening approaches, and examples of successful pathways towards clinical development. Our goal is to develop a more cohesive scientific initiative in drug discovery leading to therapeutic development of new agents and combinations in cancer. The emphasis of the retreat will be on aligning our programmatic strengths in targets, disease-based research, study design and laboratory correlatives, and exploring potential new directions in drug discovery. Please RSVP to gillian.irwin@case.edu as soon as possible. For more information and to view the retreat agenda, please click here. |
EVENTS**All events are open to anyone interested in attending June 15Research in Progress Seminar cancelled Physiology & Biophysics Seminar June 16Taussig Cancer Institute Core Curriculum Series June 17Grand Rounds June 18Taussig Cancer Institute Core Curriculum Series June 19Hematology/ Oncology Fellows Seminar Taussig Cancer Institute Grand Rounds more UPCOMING CANCER CENTER SYMPOSIUMS & EVENTSOhio Collaborative Conference on Bioinformatics (OCCBIO) Annual Breast Cancer Update: Highlights of the National Meetings Developmental Therapeutics Programs Retreat ASCO Review Case CCC Scientific Retreat 2009 Management of Lung Cancer in the Emphysema Patient: From Surgery to Cyberknife and Beyond Paradigms in Lymphoma Management: A Case Based Approach Case CCC Scientific Series **For more information on these symposiums, please contact Christine Rhoads. ADDITIONAL UPCOMING SEMINARS & EVENTSProstate Cancer Forum: A Pathway to Support, Education and Empowerment 2nd Annual Business Education Course The Business of Regenerative Medicine: From Stem Cells to the Market Place 2009 caBIG® Annual Meeting: Solving Basic and Clinical Research Challenges in Cancer and Beyond ACS Pan Ohio Hope Ride MSC2009: The Regenerative Medicine and Adult Stem Cell Therapy Conference ASCO Breast Cancer Symposium Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop |
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CALL FOR ABSTRACTS– 2009 Case CCC Breast Cancer RetreatThe Case Comprehensive Cancer Center is planning a one-day Breast Cancer Research Retreat for mid-September, and is inviting all members of the Cancer Center community to attend. The abstracts that are chosen will be incorporated into the agenda either by giving a short talk or presenting a poster. We look forward to a stimulating and informative retreat. Please contact Retreat Co-Directors, Ruth Keri, PhD or Mark Jackson, PhD with any questions. Please send abstracts by August 1, 2009 via email to: Gillian Irwin. NCI NEWS– Approved Oncology Drugs Now Available from DCTD in Plated SetsThe NCI Division of Cancer Treatment and Diagnosis can now bring a new, important resource to drug discovery efforts. Oncology drugs that have been approved by the Food and Drug Administration are being offered in plated sets. A collection of more than 50 oncology drugs is currently available and approximately 30 other drugs will become obtainable soon. The compounds are provided as 20 microliters at 10mM in 100% DMSO. For more information, please click here. AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO) ANNUAL MEETING PRESENTATIONS & POSTERSThe Case CCC was well represented at the ASCO Annual Meeting, held May 29 - June 2 in Orlando, Florida. The following people were involved in the general meeting program as session co-chairs, or session/discussion participants: Drs. Robert Dreicer, Jorge Garcia, Timothy Gilligan, Eric Klein, Eric Kodish, Smitha Krishnamurthi, Derek Raghavan, Brian Rini, and Vivien von Gruenigen. Also, the following abstracts were presented by Cancer Center Members: CALL FOR PARTICIPATION– Ohio Collaborative Conference on BioinformaticsThe Ohio Bioinformatics Consortium will hold the 4th Annual Ohio Collaborative Conference on Bioinformatics (OCCBIO) on June 15-17 at Case Western Reserve University. The conference provides an interdisciplinary forum for the discussion of methods, research findings, and experiences. An important goal for the conference is to foster long-term collaborative relationships and networking opportunities within the domain of computational approaches to biology that benefit Ohio. Keynote Speakers: Tao Jiang, Presidential Chair Professor, University of California - Riverside Daniel R. Schoenberg, Center for RNA Biology and Department of Molecular and Cellular Biochemistry, The Ohio State University For more information about this event, please click here. |
FUNDING OPPORTUNITY– Susan G. Komen for the Cure Promise Grants: Special Focus on PreventionSusan G. Komen for the Cure is accepting pre-applications for Prevention Promise Grants. These grants seek to support integrated programs of collaborative and cross-disciplinary research projects leading to the aggressive translation of scientific discoveries into interventions and strategies that have the greatest potential to significantly reduce breast cancer incidence, defined here in terms of the prevention of primary breast cancers in previously asymptomatic women or prevention of second primary breast cancers in women with a previous history of cancer. Proposals seeking to prevent breast cancer recurrence would not be within the scope of this RFA. These grants seek to remove current roadblocks to development and clinical translation of effective prevention interventions. Awards will provide up to $5million over 3-5 years. Pre-application Deadline: July 15 For more information, please click here. FUNDING OPPORTUNITY– International Myeloma Foundation 2010 Brian D. Novis Research AwardsThe International Myeloma Foundation funds several research grants including the Brian D. Novis Research Award. These grants are provided through donations from private individuals, and are presented annually by the International Myeloma Foundation. These awards go to doctors/researchers doing work in the field of multiple myeloma. The Brian D. Novis Award honors the IMF's founder Brian Novis, who died of multiple myeloma in July of 1992. The International Myeloma Foundation is a non-profit organization whose mission is to improve the quality of life for myeloma patients while working toward prevention and a cure. Junior Research Award Senior Research Award CALL FOR INTEREST– NCI 2009 Translational Science Meeting (TSM2)The National Cancer Institute is sponsoring the 2009 Translational Science Meeting (TSM2) on November 5-7, 2009 at the Sheraton Premiere in Vienna, VA. The purpose of the meeting is to enhance collaborations and interactions among investigators supported across all NCI funding mechanisms that support translational research. In addition, it will assist in the identification of Translational Research Opportunities as a part of NCI's new Process to Accelerate Translational Science initiative to advance the most promising translational research projects. Additional information on the 2009 NCI Translational Science Meeting can be found at http://ncitranslates.nci.nih.gov. The Case CCC has been invited to select one investigator to represent our Center and submit an abstract on their translational work. In addition, we have reserved one non-presenting position so a second member of our Center can attend the meeting and actively participate in the discussion sessions. Our center will need to register and submit our abstract by July 1, 2009. If you would like to be considered for this opportunity to represent the Case CCC, please send your abstract to gillian.irwin@case.edu by Monday, June 22. |
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PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES |
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Brain Tumor Funders' Collaborative |
Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants |
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NIH Bulletin – Notices and Funding OpportunitiesExploratory Grant Award to Promote Workforce Diversity in Basic Cancer Research (R21) (PAR-09-162) Translational Research at the Aging/Cancer Interface (TRACI) (R01) (PA-08-230) Diet-Induced Changes in Inflammation as Determinants of Colon Cancer (R01) (PA-08-210) Biomarkers for Early Detection of Hematopoietic Malignancies (R01) (PA-09-197) Biomarkers for Early Detection of Hematopoietic Malignancies (R21) (PA-09-198) |
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| Produced by: Gillian Irwin 11100 Euclid Avenue, Wearn 152 Cleveland, Ohio 44106-5065 216-844-8317 phone 216-844-7832 fax gillian.irwin@case.edu Janice Hassinger 11100 Euclid Avenue, Wearn 149 Cleveland, Ohio 44106-5065 216-844-1862 phone 216-844-7832 fax janice.hassinger@uhhospitals.org |
HELP US HELP YOU!If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to gillian.irwin@case.edu. |
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