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Case Comprehensive Cancer Center Newsletter

May 25, 2009

CASE CCC IN THE NEWS

Is There Any Association Between COX2 and Colon Cancer?
EurekAlert (press release) - May 22, 2009
The research team led by Dr. Li from Case Western Reserve University examined the association of variants of the COX2 and UGT1A6 genes, ...

Pink Tie Guys Don Fashion Accessory for Komen to Help Raise ...
The Plain Dealer - cleveland.com - May 19, 2009
Dr. Stanton Gerson wasn't able to attend last week's event, but the director of University Hospital's Ireland Cancer Center said getting him to add one...

Medical Community Continues Debate on Age Limit for Cancer Screenings
The Plain Dealer - cleveland.com - May 19, 2009
Dr. Derek Raghavan, director of the Taussig Cancer Institute at the Cleveland Clinic, has come out against prostate cancer screening for men over age 75. ...

Small Gains Made in Studying Treatment of Elderly
The Plain Dealer - cleveland.com - May 19, 2009
... so we don't have evidence [of a treatment's effectiveness in that group of people] and that's what we're struggling against," said Dr. Cynthia Owusu, ...

As Aged Population Grows, More Doctors Say it's Not Too Late to ...
The Plain Dealer - cleveland.com - May 19, 2009
The Case Comprehensive Cancer Center was one of eight institutions that received money in that received money in 2003 as part of a five-year, $25 million federal grant to create geriatric oncology programs ...

Discovery In Colon Cancer Prevention
Science Daily (press release) - May 19, 2009
The study, published in this week's issue of the Proceedings of the National Academy of Sciences (PNAS), is by Sanford Markowitz, MD, PhD, ...

CWRU, University Hospitals Research Questions Celebrex Effectiveness Against Colon Cancer
The Plain Dealer - cleveland.com - May 18, 2009
The study, published in this week's Proceedings of the National Academy of Sciences, was led by Dr. Sanford Markowitz, professor of cancer genetics at Case ...

NIDA Awards Case Western Reserve $3M to Use Proteomics to Study ...
GenomeWeb Daily News - May 13, 2009
The money will be used to hire new personnel to do the research and fund three pilot projects, Mark Chance, director of the Center for Proteomics and ...

Study: Drug Lowers Risk of Getting Prostate Cancer
The Associated Press - Apr 27, 2009
... one man who had two brothers with prostate cancer, said Dr. Lee Ponsky, prostate cancer chief at University Hospitals Case Medical Center in Cleveland. ...


NEW MEMBERS CORNER

Please join us in welcoming the following new members of the Case CCC:

Harry Gill, PhD
Assistant Professor, Physiology & Biophysics
Developmental Therapeutics Program

Donna Hansel, MD, PhD
Assistant Professor, Pathology
GU Malignancies Program

Neena Singh, MD, PhD
Associate Professor, Pathology
Cell Death Regulation Program


AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO) ANNUAL MEETING PRESENTATIONS & POSTERS

The Cancer Center is attempting to track members who are part of the formal program or presenting a poster at the ASCO Annual Meeting, May 29 - June 2 in Orlando, Florida. Please send information to gillian.irwin@case.edu.


FUNDING OPPORTUNITY– William Lawrence & Blanche Hughes Foundation

The William Lawrence & Blanche Hughes Foundation is a non-profit organization whose major goal is to foster discoveries in pediatric acute lymphocytic leukemia with a goal of developing effective therapies for the disease. Applicants must be either established investigators with an association to an academic institution, or working closely with and part of a lab of an established investigator.

Deadline: September 16

For more information, please click here.


FUNDING OPPORTUNITY– ASCO Cancer Foundation Improving Cancer Care Grant, funded by Susan G. Komen for the Cure

The ASCO Cancer Foundation® Improving Cancer Care Grant, funded by Susan G. Komen for the Cure®, will provide extramural research funding to address important issues regarding access to healthcare, quality of care, and delivery of care, with general applicability to breast cancer. The goal of this program is to encourage multi-disciplinary research that will have a major impact on cancer care, with general applicability in the breast cancer arena. This grant opportunity is part of the Susan G. Komen for the Cure/ASCO Cancer Foundation Research Initiative.

Susan G. Komen for the Cure and The ASCO Cancer Foundation expect to award up to three research grants, each totaling 1.35 million dollars. This money will be distributed as $450,000 total costs per year over three years.

Online Application Opens: July 1
LOI Deadline: September 1

For more information, please click here.


MARK YOUR CALENDARS– Prostate Cancer Forum: A Pathway to Support, Education and Empowerment

Prostate Cancer Forum: A Pathway to Support, Education and Empowerment, is an all-day forum that will cover a variety of topics, including sexuality, osteoporosis, genetic issues, incontinence, and complementary therapies. All sessions are open to spouses, significant others and family members. This event is scheduled for Saturday, June 20 from 8:30 am - 5:00 pm at Corporate College East, 4400 Richmond Road, Warrensville Heights.

Cancer Center members Drs. Edward Cherullo, Jay Ciezki, Douglas Einstein, and Charles Nock are scheduled to present.

This program is free, but advance registration is required. For more information, please contact The Gathering Place at 216-595-9546 or info@touchedbycancer.org.

This forum is sponsored by Ireland Cancer Center, with additional sponsorship provided by the American Cancer Society, the Cleveland Clinic, the Gathering Place, and the Foundation for Cancer Research and Education.


MARK YOUR CALENDARS– Race for the Place

Join The Gathering Place on Sunday, June 7, National Cancer Survivors Day, for the 9th Annual Race for the Place, a 5k run/walk and 1-mile walk. The race starts at 9:15 am at Beachwood Mall on the upper level parking lot between Dillards and Nordstrom with several pre-race activities beginning at 8:00 am. All proceeds from Race for the Place help keep programs and services free of charge for individuals and families touched by cancer.

For details and registration information, please click here.

EVENTS

**All events are open to anyone interested in attending

May 25

Happy Memorial Day!


May 26

Neurosciences Special Seminar
Adriano Flora, PhD
Postdoctoral Associate, Molecular & Human Genetics
Baylor College of Medicine
Topic: Doing the Math: Regulation of Sonic Hedgehog Signaling in the Developing Cerebellum and in Medulloblastoma
12:00 pm SOM E501

Taussig Cancer Institute Core Curriculum Series
Abdo Haddad, MD
Associate Staff, Solid Tumor Oncology
Cleveland Clinic
Topic: Geriatric Oncology
12:00 pm R3-002 Cleveland Clinic


May 27

Grand Rounds
Sami Malek, MD
Assistant Professor, Medicine- Hem/Onc
University of Michigan
Topic: Translational Genomics in Leukemia
8:00 am Lerner Tower B-151

Stem Cell Biology and Regenerative Medicine Guest Lecture
Mahendra Rao, MD, PhD
Vice President, Invitrogen
Regenerative Medicine Department
Topic: Neurogenesis in the Nervous System
9:00 am NC1-202 Cleveland Clinic


May 28

Neurosciences Seminar
Daniel R. Storm, PhD
Professor, Pharmacology
University of Washington
Topic: Molecular Mechanisms Underlying Memory Formation: Role of Signal Transduction Cross-Talk
12:10 pm BRB 105

TREC Seminar
Sanjay Patel, MD
Assistant Professor, Medicine-Pulmonary & Critical Care, Sleep Medicine
CWRU/ UH
Topic: Effects of Sleep on Adipose Tissue
4:00 pm BRB 732


May 29

Cancer Center Seminar Series/ Blood Club cancelled

Taussig Cancer Institute Grand Rounds cancelled

Hematology/ Oncology Fellows Seminar cancelled

Cell Biology Seminar
Xin Chen, PhD
Assistant Professor, Biology
Johns Hopkins University
Topic: Epigenetic Regulation of Cellular Differentiation in a Stem Cell Lineage
10:00 am NC1-202 Cleveland Clinic

more

For a complete listing of LRI seminars click here.


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Ohio Collaborative Conference on Bioinformatics (OCCBIO)
June 15 - 17
CWRU campus
Details

Annual Breast Cancer Update: Highlights of the National Meetings
June 19
Marriott Cleveland East, Warrensville Heights
Brochure and Registration

Drug Discovery and Developmental Therapeutics Retreat
June 20
9:00 am - 2:00 pm Squire Valleevue Farm Sheep Barn
Details

ASCO Review
June 25
InterContinental Hotel
Details

Case CCC Scientific Retreat 2009
July 10-11
Bertram Inn & Conference Center, Aurora
Details to follow

Case CCC Scientific Series
October 8
4:00 pm - 6:00 pm WRB 1-413

**For more information on these symposiums, please contact Christine Rhoads.


ADDITIONAL UPCOMING SEMINARS & EVENTS

Center for Mind-Body Medicine CancerGuides® II
June 11 - 14
Washington, DC
Details

2nd Annual Business Education Course The Business of Regenerative Medicine: From Stem Cells to the Market Place
July 13-16
George S. Dively Building, CWRU Campus
Details

2009 caBIG® Annual Meeting: Solving Basic and Clinical Research Challenges in Cancer and Beyond
July 20 – 22
Marriott Wardman Park, Washington, DC
Details

ACS Pan Ohio Hope Ride
July 30 - August 2
Details

MSC2009: The Regenerative Medicine and Adult Stem Cell Therapy Conference
August 17-19
Cleveland Marriott Downtown at Key Center
Details

ASCO Breast Cancer Symposium
October 8-10
San Francisco Marriott
San Francisco, CA
Details

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, Arizona
Details


NCI CANCER BULLETIN

News
Featured Article: An Experimental Treatment Improves Survival for Patients with Neuroblastoma

Ginger Helps Reduce Nausea from Chemotherapy

Sentinel Lymph Node Biopsy Suitable for Staging Penile Carcinoma

Three Genes Help Breast Cancer Invade the Brain

DEAR1 Gene May Help Drive Early-onset Breast Cancer

Formaldehyde May Cause Some Blood Cancers, but Risk Drops over Time

Guest Director's Update
Dr. Robert Yarchoan, Director, NCI's Office of HIV and AIDS Malignancy: Marking a Memorable Moment in AIDS Research

In Depth
Special Report: Decades Later, Seeing the Benefits of Radiation after Prostate Surgery

Spotlight: Comparative Effectiveness Research Stirs Excitement as Well as Debate

Featured Clinical Trial: Cetuximab and Chemoradiotherapy for Locally Advanced Esophageal Cancer


MARK YOUR CALENDARS– Pan Ohio Hope Ride Research Rally

On May 30, the American Cancer Society will be sponsoring the Pan Ohio Hope Ride Research Rally to celebrate the cancer research going on in the Cleveland area and to raise awareness of the Third Annual ACS Pan Ohio Hope Ride to be held July 30 - August 2.

The Research Rally will begin at 9:00 a.m. in front of the ACS Hope Lodge at 11432 Mayfield Rd. After a brief program, the riders will proceed down Euclid Avenue to Public Square and loop around back at the Hope Lodge.

Everyone in the local oncology community is encouraged to participate in the approximately 10-mile bike ride.

Anyone interested in participating should contact Paul Purdy, ACS Pan Ohio Staff, at Paul.purdy@cancer.org or 888-227-6446, ext. 1208. For more information, please click here.


MARK YOUR CALENDARS– ACS Pan Ohio Hope Ride

The American Cancer Society's Pan Ohio Hope Ride is a bicycling tour that enables you to take an incredible bicycle journey and to support ACS Hope Lodges and other vital patient services. The Pan Ohio Hope Ride will take cyclists from Cleveland to Cincinnati in a four-day tour through Ohio's scenic countryside from July 30 - August 2. Challenge yourself to hit the road and make the road smoother for those battling cancer.

For more information, please click here.



MARK YOUR CALENDARS– Drug Discovery and Developmental Therapeutics Retreat

Join your colleagues on Saturday, June 20 from 9:00 am - 2:00 pm at the Squire Valleevue Farm Sheep Barn for a broad scientific discussion of new drug targets, screening approaches, and examples of successful pathways towards clinical development.

Our goal is to develop a more cohesive scientific initiative in drug discovery leading to therapeutic development of new agents and combinations in cancer. The emphasis of the retreat will be on aligning our programmatic strengths in targets, disease-based research, study design and laboratory correlatives, and exploring potential new directions in drug discovery.

Anyone with a poster related to this theme is encouraged to present it at the retreat. Please let us know if you plan on bringing one so we can make arrangements.

Agenda will be released soon. Please RSVP to gillian.irwin@case.edu by Friday, June 5.


MARK YOUR CALENDARS– Ohio Collaborative Conference on Bioinformatics (OCCBIO)

The fourth annual Ohio Collaborative Conference on Bioinformatics (OCCBIO) will be hosted by Case Western Reserve University on June 15-17. The conference provides an interdisciplinary forum for the discussion of methods, research findings, and experiences. An important goal for the conference is to foster long-term collaborative relationships and networking opportunities within the domain of computational approaches to biology that benefit Ohio.

Poster Presentation Abstracts are due by May 11 for review by the OCCBIO '09 committee. All appropriate posters submitted will be accommodated.

For more information, please click here.


CALL FOR ABSTRACTS– Fanconi Anemia Research Fund

The Fanconi Anemia Research Fund has released a Call for Abstracts for the 21st Annual Fanconi Anemia Research Fund Scientific Symposium, schedule for October 1-4, 2009 at the Baltimore Marriott Waterfront in Baltimore, Maryland. Abstracts may be submitted online at http://www.fanconi.org May 11- June 19.


PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Damon Runyon-Rachleff Innovation Award
Pre-proposal Deadline: June 1

Susan G. Komen for the Cure Investigator-Initiated Research (IIR) Grants
Pre-Application Deadline: June 1
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Pre-Application Deadline: June 1
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst in Disparities Research (CCDR) Grants
Pre-Application Deadline: June 1
Full Application Deadline: July 31

Brain Tumor Funders' Collaborative
Deadline: June 15

BCRP Impact Awards
BCRP Multi-Team Awards
BCRP Era of Hope Scholar Awards
BCRP Innovator Awards
Application Deadline: June 17

Doris Duke Charitable Foundation Innovation in Clinical Research Award Competition
Proposal Deadline: July 8

NCRR Competitive Revision Application
Deadline: July 10

DOD PCRP Prostate Cancer Pathology Resource Network Award
Pre-Application Deadline: July 15
Proposal Deadline: August 5


Susan G. Komen for the Cure Investigator-Initiated Research (IIR) Grants
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst Research (CCR) Grants
Full Application Deadline: July 31

Susan G. Komen for the Cure Career Catalyst in Disparities Research (CCDR) Grants
Full Application Deadline: July 31

DOD PCRP Prostate Cancer Pathology Resource Network Award
Pre-Application Deadline: July 15
Proposal Deadline: August 5

Mesothelioma Applied Research Foundation
Deadline: August 15

Damon Runyon Cancer Research Foundation Fellowships
Deadline: August 17

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Technology Development for the Detection and Evaluation of Chemical and Biological Carcinogens (SBIR) [R43/R44] (PA-09-187)

Technologies and Software to Support Integrative Cancer Biology Research (SBIR) [R43/R44] (PA-09-188)

Technology for the Detection and Characterization of Low Abundance Proteins, Peptides, or micro RNAs (SBIR) [R43/R44](PA-09-189)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

Janice Hassinger
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
janice.hassinger@uhhospitals.org

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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