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Case Comprehensive Cancer Center Newsletter

April 6, 2009

MARK YOUR CALENDARS– Case CCC Clinical Trials Faculty Retreat

The Case Comprehensive Cancer Center is hosting a Clinical Trials Faculty Retreat on Monday, April 13 from 5:30 pm - 8:30 pm at the InterContinental Hotel.

This retreat will give clinical researchers from Ireland Cancer Center and Taussig Cancer Institute main campuses and regional networks the chance to interact.

The program will include:
• Overview of the Case Comprehensive Cancer Center research program

• Update of some featured trials from the GU and Lung groups

• Opportunity for exchange of ideas on how to improve our joint clinical research efforts and accrual to trials across our network.

Please RSVP to Christine Rhoads, cmr4@case.edu, 844-1675.


Everyone is invited to stop by the Case CCC booth at Research ShowCASE on Thursday, April 16 from 9:00 am - 5:00 pm in the Veale Convocation Center on the CWRU campus. Research ShowCASE is a free event open to the public where hundreds of scientists and scholars gather to celebrate the broad range of research currently being conducted at CWRU and its affiliates.

For more information, including a complete program schedule, registration, parking, directions, maps and lodging, please visit showcase.case.edu or call (216) 368-2932.

MARK YOUR CALENDARS- Thoracic Malignancies 2009: Up For Debate

The Case CCC is pleased to announce the upcoming course, Thoracic Malignancies 2009: Up for Debate, on April 18 at the InterContinental Hotel & Bank of America Conference Center. This one day course will provide a topical, clinically based overview of the current therapy dilemmas faced by clinicians managing lung and esophagus cancers, and mesothelioma, with an emphasis on the opportunity for multidisciplinary management. Medical oncologists, radiation oncologists, pulmonologists, thoracic surgeons, and internists are encouraged to attend.

For more information, please click here.

MARK YOUR CALENDARS–MSC2009: The Regenerative Medicine and Adult Stem Cell Therapy Conference

Registration for MSC2009: The Regenerative Medicine and Adult Stem Cell Therapy Conference is now open. MSC2009, which will take place in Cleveland, August 17-19, will offer a forum for the exchange and discussion of research, ideas, and cutting-edge breakthroughs in translational regenerative medicine.

The breadth of topics from basic discovery through model validation, clinical product development, and therapeutic application, in addition to the links between academic and commercial labs, make this conference imperative for industrial researchers, academic investigators, and graduate and post-doctoral students.

For details including registration information, please click here.

MARK YOUR CALENDARS– Seventh Annual Cancer Survivorship Series: Living With, Through & Beyond Cancer

The Seventh Annual Cancer Survivorship Series: Living With, Through & Beyond Cancer, is a free three-part telephone education workshop program made possible by CancerCare and with support from the National Cancer Institute and Lance Armstrong Foundation, offers cancer survivors, their families, friends and health care professionals practical information to help them cope with concerns and issues that arise after treatment ends.

Part I: Managing the Stress of Survivorship, April 14 1:30 – 2:30 pm, ET.

Part II: The Importance of Nutrition and Physical Activity, May 19 1:30 – 2:30 pm, ET.

Part III: Survivors Too: Family, Friends and Loved Ones: Managing the Fatigue of Caregiving, June 23 1:30 – 2:30 pm, ET.

These workshops are free – no phone charges apply. However, pre-registration is required. To register simply go to the CancerCare website.

FUNDING OPPORTUNITY– American Cancer Society IRG Awards

The Case CCC is accepting applications for American Cancer Society (ACS) IRG pilot funding for cancer-related research in basic, clinical, prevention & control, behavioral, health services and epidemiology. These pilot project grants are intended to support independent, self-directed investigators early in their careers (usually assistant professor or equivalent). Applicants for the pilot project grants should be within six years of their first independent research or faculty appointment and eligible to apply for independent national competitive research grants, but may not currently hold such a grant.

Recipients of IRG pilot project grants must be, at the time of the application, citizens or noncitizen nationals of the United States or its possessions and territories, or must have been lawfully admitted to the United States for permanent residence at the time of application.

Application Deadline: TODAY April 6

Instructions, frequently asked questions, and applications available at http://cancer.case.edu. Contact Terri Daso, Cancer Center Administration, 844-7252, tld6@case.edu for more information.

FUNDING OPPORTUNITY– Damon Runyon-Rachleff Innovation Award

The Damon Runyon-Rachleff Innovation Award provides support for the next generation of exceptionally creative thinkers with "high risk/high reward" ideas that have the potential to significantly impact our understanding of and/or approaches to the prevention, diagnosis and treatment of cancer. This award is specifically designed to provide funding for extraordinary early career researchers who have an innovative, new idea but lack sufficient preliminary data to obtain traditional funding.

The research supported by the award must be novel, exceptionally creative and, if successful, have the strong potential for high impact in the cancer field. Eligible applicants (including non-U.S. citizens) must be conducting independent research at a U.S. institution.

Institutional nominations are not required and there is no limit to the number of applications that can be received from a particular institution. Basic and translational/clinical projects will be considered and individuals with a background in multiple disciplines are especially encouraged to apply. The awards will provide $450,000 in direct costs during a three year award term.

Pre-proposal Deadline: June 1

For more information, please click here.


**All events are open to anyone interested in attending

April 6

Hematology/Oncology Research in Progress Seminar cancelled

Pathology Research Seminar
Michelle Kelliher, PhD
Associate Professor, Cancer Biology
University of Massachusetts
Topic: NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium Tuberculosis
12:00 pm WRB 1-413

Physiology & Biophysics Seminar
Anton Bennett, PhD
Associate Professor, Pharmacology
Yale University
Topic: Signaling Mechanisms of Protein Tyrosine Phosphatases in Disease
4:00 pm SOM E501

April 7

April 8

Grand Rounds
Patrick Ma, MD
Assistant Professor, Div. of Hem/Onc
Topic: Multitargeted Therapy Against MET and ERBB-Receptors to Optimize Non-Small Cell Lung Cancer Treatment
8:00 am Lerner Tower B-151

CSCRM Seminar
Edward Stavnezer, PhD
Professor, Biochemistry
Topic: Contrasting Roles of the Ski Proto-Oncogene in Muscle Development and Differentiation
4:30 pm NA5-08 Cleveland Clinic

April 9

Neurosciences Seminar cancelled

April 10

Taussig Cancer Institute Grand Rounds cancelled

Cancer Center Seminar Series/ Blood Club cancelled

Neurological Institute Seminar
Jan Buckner, MD
Professor, Oncology
Mayo Clinic
Topic: The Emerging Role of VEGF Pathway Inhibitors in Glioma Therapy: More Questions than Answers?
6:45 am R3/002-003 Cleveland Clinic

Hematology/ Oncology Fellows Seminar
Cecilia Choi, MD
Fellow, Div. of Hem/Onc
Topic: Updates in Guidelines for Non-Small Cell Lung Cancer, Colorectal Cancer, and Non-Hodgkin's Lymphoma
8:00 am Wearn 137

Biomedical Engineering Seminar
Eric Bachelder, PhD
University of California at Berkley
Topic: Acid-Labile Particles for Cancer Immunotherapeutic Applications
2:00 pm NA1-140 Cleveland Clinic


For a complete listing of LRI seminars click here.


Visual Sciences Research Center/ Case CCC Special Seminar
April 14
Vincent Cryns, MD
Associate Professor, Medicine
Northwestern University
Topic: αB-Crystallin: Portrait of a Malignant Chaperone
3:00 pm WRB 1-413

Case CCC Scientific Series
May 11
4:00 pm - 6:00 pm WRB 1-413

October 8
4:00 pm - 6:00 pm WRB 1-413

Signaling in Cancer
May 18-19
Wolstein Research Building (CWRU Campus)

Ohio Collaborative Conference on Bioinformatics (OCCBIO)
June 15 - 17
CWRU campus

Annual Breast Cancer Update: Highlights of the National Meetings
June 19
Marriott Cleveland East, Warrensville Hts
Brochure and Registration

ASCO Review
June 25
InterContinental Hotel
Details to follow

Case CCC Scientific Retreat 2009
July 10-11
Bertram Inn & Conference Center, Aurora
Details to follow

**For more information on these symposiums, please contact Christine Rhoads.


AACR Annual Meeting
April 18 - 22
Colorado Convention Center
Denver, CO

Neuropathic Cancer Pain Symposium
April 27
Bethesda Marriott Pooks Hill
Bethesda, MD

11th Annual Midwest DNA Repair Symposium
May 16-17
BSRB Auditorium, University of Michigan
Ann Arbor, MI
Abstract Deadline: May 1

ASCO Breast Cancer Symposium
October 8-10
San Francisco Marriott
San Francisco, CA

FUNDING OPPORTUNITY– AACR Scholar-in-Training Awards - Special Conferences

The AACR offers Scholar-in-Training Awards to enhance the education and training of early career scientists by providing financial support for their attendance at AACR Special Conferences. These awards are provided to offset a portion of the registration, travel, and subsistence expenses incurred in attending these conferences.

These awards are open to all graduate and medical students, postdoctoral fellows, and physicians-in-training who submit abstracts. Individuals wishing to apply for one of these awards should check the appropriate box when submitting their abstract online. Applicants must be listed as the presenter of the abstract. To be considered for an award, applicants must also submit a letter of recommendation from their program supervisor or department head that describes the quality of their clinical and/or experimental work. Deadline varies depending on the conference applicant will be attending.

For more information, please click here.

FUNDING OPPORTUNITY– Proteomics and Bioinformatics Pilot Research Award

The Center for Proteomics and Bioinformatics is currently accepting applications for the Proteomics and Bioinformatics Pilot Research Award. This award seeks to support up to five research projects that will utilize the facilities of the Center. This program was designed with the understanding that the principal investigator will form a collaboration with the Center and subsequently apply for NIH or equivalent funding using preliminary data acquired during the project period. Funding priority will be given for the following criteria: (1) Applicants who have not yet attained tenure or promotion to the full professor level; (2) Projects with a high likelihood of subsequent national-level funding; (3) Research in the areas of expression proteomics, post-translational modifications, systems biology data analysis, structural mass spectrometry, protein crystallography, and interaction proteomics.

Deadline: May 1

For more information and to download the application, please visit http://proteomics.case.edu. For inquiries, please contact Joan Schenkel at joan.schenkel@case.edu.

FUNDING OPPORTUNITY– James S. McDonnell Foundation

The Foundation offers Collaborative Activity Awards to initiate interdisciplinary discussions on problems or issues, to help launch interdisciplinary research networks, or to fund communities of researchers/practitioners dedicated to developing new methods, tools, and applications of basic research to applied problems.

In each case the focus of the collaborative activity must meet the program guidelines for one of the following program areas:
–Bridging Brain, Mind, and Behavior
–Studying Complex Systems
–Brain Cancer Research

Applications are continuously accepted for these awards.

For more information, please click here.

MARK YOUR CALENDARS– Signaling in Cancer Symposium

The Case CCC is pleased the present the Signaling in Cancer Symposium, scheduled for May 18-19 in the Wolstein Research Building. This conference is intended for faculty, postdoctoral fellows and students interested in basic cancer research. The program is filled with many interesting presentations, including that of Keynote Speaker, Jerry E. Chipuk, PhD of St. Jude Children's Research Hospital, who will present "Mitochondrial Outer Membrane Permeabilization And Apoptosis Are Regulated By Collaborative Interactions Between Mitochondrial Physiology And BH3-Only Proteins".

Please note that students and postdoctoral fellows may attend this event for FREE. Registration is required. The deadline for registration and abstract submission is April 24.

For details, please click here. For registration information, please click here.

MARK YOUR CALENDARS– Ohio Collaborative Conference on Bioinformatics

The fourth annual Ohio Collaborative Conference on Bioinformatics (OCCBIO) will be hosted by Case Western Reserve University on June 15-17. The conference provides an interdisciplinary forum for the discussion of methods, research findings, and experiences. An important goal for the conference is to foster long-term collaborative relationships and networking opportunities within the domain of computational approaches to biology that benefit Ohio.

Poster Presentation Abstracts are due by May 11 for review by the OCCBIO '09 committee. All appropriate posters submitted will be accommodated.

For more information, please click here.

FUNDING OPPORTUNITY– Association for International Cancer Research (AICR)

AICR awards project grants of between one and three years to support fundamental and translational research into the causes, mechanisms, diagnosis, treatment and prevention of cancer. They will consider proposals in which a mixture of basic and clinical research is proposed. However, completely clinical applications, such as intervention studies, clinical trials or health care delivery research and many substantially clinical applications are beyond the remit of AICR.

Applications will be accepted April 1-24.

For details, please click here.


NFRP Clinical Trial Award
NFRP Investigator-Initiated Research Award
NFRP Exploration-Hypothesis Development Award
NFRP New Investigator Award
NFRP Postdoctoral Traineeship Award
Proposal Deadline: April 14

Peer Reviewed Medical Research Program (PRMRP)
Application Deadline: April 16

NCRR Competitive Revision Application
Deadline: April 21 and July 10

PCRP Population-Based Idea Development Award
PCRP New Investigator Award
PCRP Health Disparity Research Award
PCRP Health Disparity Training Award
PCRP Physician Research Training Award
PCRP Prostate Cancer Training Award
Pre-Application Deadline: April 29
Proposal Deadline: May 20

Paul Marks Prize for Cancer Research
Nominations Deadline: April 30

OCRP Ovarian Cancer Academy Award
Pre-App Deadline: May 8
Proposal Deadline: May 22

PCRP Population-Based Idea Development Award
PCRP New Investigator Award
PCRP Health Disparity Research Award
PCRP Health Disparity Training Award
PCRP Physician Research Training Award
PCRP Prostate Cancer Training Award
Proposal Deadline: May 20

OCRP Ovarian Cancer Academy Award
Proposal Deadline: May 22

BCRP Impact Awards
BCRP Multi-Team Awards
BCRP Era of Hope Scholar Awards
BCRP Innovator Awards
Application Deadline: June 17

NCRR Competitive Revision Application
Deadline: July 10

NCI Short-Term Scientist Exchange Program
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Notice of Public Meeting: Expansion of the Clinical Trials Registry and Results Data Bank (NOT-OD-09-077)

Recovery Act Notice: NIH ARRA Funding Considerations for Applications with Meritorious Scores that Fall Beyond the Pay-line (NOT-OD-09-078)

ARRA Administrative Supplements and Competitive Revisions: Clarifications on Programmatic Limitations and use of Modular Budgets (NOT-OD-09-079)

Recovery Act of 2009: NIH Award Terms and Additional Information for Recipients Receiving Recovery Act Grant Funding (NOT-OD-09-080)

Announcement of Participation of NCI on RFA-NR-09-004, Interventions to Improve Palliative Care at the End of Life (R01) (NOT-CA-09-020)

Allowable Salary Levels on Career Awards Supported by the National Cancer Institute (NOT-CA-09-022)

Notice of Clarification to RFA-RR-09-007 and RFA-RR-09-008 (NOT-RR-09-011)

Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers (P30) (RFA-OD-09-005)

Community-Based Partnerships for Childhood Obesity Prevention and Control: Research to Inform Policy (R03) (PA-09-140)

Community-Based Partnerships for Childhood Obesity Prevention and Control: Research to Inform Policy (R21) (PA-09-141)

Cancer Surveillance Using Health Claims-based Data System (R03) (PA-09-143)

Cancer Surveillance Using Health Claims-based Data System (R21) (PA-09-144)

Cancer Surveillance Using Health Claims-based Data System (R01) (PA-09-145)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Hassinger
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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