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Case Comprehensive Cancer Center Newsletter

March 2, 2009

CASE CCC IN THE NEWS

Triple-Negative Breast Cancers Express MUC-1 Target Found
eMaxHealth.com - Feb 24, 2009
Joseph Baar, MD, PhD, Director of Breast Cancer Research at the Ireland Cancer Center, and colleagues analyzed 53 tumors and determined that 92 percent of..... been nothing to offer women with triple negative breast cancer beyond standard therapy," says Stanton Gerson, MD, Director of the Ireland Cancer Center...

Imalux Corporation and Preventive Oncology International, Inc ...
Business Wire (press release) - Feb 24, 2009
... and efficient method for a single episode of care ('see and treat') for cervical dysplasia," stated Dr. Jerome Belinson,...

Daily use of hormone-lowering drug recommended to cut risk of ...
The Plain Dealer - cleveland.com - Feb 24, 2009
Dr. Lee Ponsky, chief of the Division of Urologic Oncology at University Hospitals Case Medical Center, had just finished talking to a patient about ...


MARK YOUR CALENDARS– Case CCC Scientific Series: Transcriptional Regulatory Networks in Breast Cancer

Please mark your calendars for the next installment of the Case CCC Scientific Series, Transcriptional Regulatory Networks in Breast Cancer. Drs. Ruth Keri, Monica Montano, Noa Noy, Mukesh Jain, and Julian Kim will present on their pilot projects, which were funded by the Breast Cancer Working Group. This event is scheduled for Tuesday, March 24 in Wolstein Auditorium; the program will begin at 4:00 pm, with a reception immediately following. All are encouraged to attend.


FUNDING OPPORTUNITY–DOD Prostate Cancer Research Program (PCRP) Awards

The overall goal of the Prostate Cancer Research Program (PCRP) is to find and fund innovative, high-impact research relevant to the prevention, detection, diagnosis, and/or treatment of human prostate cancer.

The PCRP recently released the following funding Program Announcements:

Population-Based Idea Development Award
New Investigator Award
Health Disparity Research Award
Health Disparity Training Award
Physician Research Training Award
Prostate Cancer Training Award

Pre-Application Deadline: April 29
Proposal Deadline: May 20

For details, please click here.


FUNDING OPPORTUNITY– ACS Postdoctoral Fellowships

The American Cancer Society (ACS) is accepting applications for the following Postdoctoral Awards:

Research Scholar Grants in Basic, Preclinical, Clinical, and Epidemiology Research
Support for investigator-initiated research projects in basic, preclinical, clinical and epidemiology research. The maximum award is for 4 years and for as much as $200,000 per year (direct costs), plus 20% allowable indirect costs. Eligibility Criteria: Investigators in the first six years of an independent research career or faculty appointment are eligible to apply.

Research Scholar Grants in Cancer Control and Prevention: Psychosocial and Behavioral Research
Support for investigator-initiated research projects in psychosocial and behavioral research, including epidemiologic approaches to psychosocial and behavioral research. Awards may be for four years and for as much as to $200,000 per year (direct costs), plus 20% allowable indirect costs. Eligibility Criteria: Investigators in the first six years of an independent research career or faculty appointment are eligible to apply.

Research Scholar Grants in Cancer Control and Prevention Health Services and Health Policy Research
Support for investigator-initiated research projects in health services and health policy research. Awards are may be for four years and for as much as $200,000 per year (direct costs), plus 20% allowable indirect costs. Eligibility Criteria: These grants are open to investigators at any stage of their career.

Postdoctoral Fellowships
Support for the training of researchers who have received a doctoral degree to provide initial funding leading to an independent career in cancer research (including basic, preclinical, clinical, cancer control, psychosocial, behavioral, epidemiology, health services and health policy research). Awards may be for three years with progressive stipends of $44,000, $46,000, and $48,000 per year, plus a $4,000 per year fellowship allowance. Depending on availability of special endowment funds, the Society annually selects one or more of the top-ranked fellowships to be supplemented above the standard stipend. During the second or third year of the award, ACS Postdoctoral Fellows will be invited to attend a Fellows Symposium to present their work, meet with senior leaders in cancer research, and develop additional professional skills important in their transition to independent research careers.

Mentored Research Scholar Grants in Applied and Clinical Research
Support for mentored research by full-time faculty, typically within the first four years of their appointment, with the goal of becoming independent investigators in clinical, cancer control and prevention, epidemiologic, psychosocial, behavioral, health services and health policy research. Awards are for up to five years and for up to $135,000 per year (direct costs), plus 8% allowable indirect costs. A maximum of $10,000 per year for the mentor(s) (regardless of the number of mentors) is included in the $135,000.

Physician Training Awards in Preventive Medicine
Awards to institutions to support physician training in accredited preventive medicine residency programs that provide cancer prevention and control research and practice opportunities. Awards are for four years in the total amount of $300,000, based on an average of $50,000 per resident training year. These grants are renewable.

The deadline for all of these awards is April 1.

For more information, please click here.


NCI CANCER BULLETIN

News
Featured Article: Years Before Myeloma, Blood Shows Changes

Possible Prostate Cancer Marker Found

Fertility Treatments Unlikely to Raise Ovarian Cancer Risk

Liver Cancer Incidence Continues Steep Climb

Compounds Found in Green Tea Block Bortezomib

Gene Provides Target for Thyroid Cancer Treatment

New ASCO/AUA Guideline for Prostate Cancer Prevention

Director's Update
Moving Ahead with the Stimulus Funds


FUNDING OPPORTUNITY– American Cancer Society IRG Awards

The Case CCC is accepting applications for American Cancer Society (ACS) IRG pilot funding for cancer-related research in basic, clinical, prevention & control, behavioral, health services and epidemiology. These pilot project grants are intended to support independent, self-directed investigators early in their careers (usually assistant professor or equivalent). Applicants for the pilot project grants should be within six years of their first independent research or faculty appointment and eligible to apply for independent national competitive research grants, but may not currently hold such a grant.

Recipients of IRG pilot project grants must be, at the time of the application, citizens or noncitizen nationals of the United States or its possessions and territories, or must have been lawfully admitted to the United States for permanent residence at the time of application.

Application Deadline: April 6

Instructions, frequently asked questions, and applications available at http://cancer.case.edu. Contact Terri Daso, Cancer Center Administration, 844-7252, tld6@case.edu for more information.

EVENTS

**All events are open to anyone interested in attending

March 2

Hematology/Oncology Research In Progress Seminar
Jonathan Kenyon
Graduate Student, Gerson Lab, Div. of Hem/Onc
CWRU/ UH
Topic: Aging Hematopoietic Stem Cells and the DNA Mismatch Repair Pathway
12:00 pm WRB 2-136

Pathology Research Seminar
Randal Kaufman, PhD
Professor, Biological Chemistry and Internal Medicine
University of Michigan
Topic: Protein Folding, Oxidative Stress and the Unfolded Protein Response
12:00 pm WRB 1-413


March 3


March 4

Grand Rounds
Greg Chipman, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: Targeted Therapy in Colon Cancer
8:00 am Lerner Tower B-151

Neurosciences Seminar
Jerrold Vitek, MD, PhD
Neurosciences
Cleveland Clinic
Topic: Electricity for the Brain: What it can do for Neurologic Disorders and How it Does it
12:10 pm BRB 105


March 5

Case CCC/ Epidemiology & Biostatistics Faculty Candidate Seminar
Hao Wang, MS
Staff Biostatistician, University of Pennsylvania
Topic: Modeling Heaping in Self-Reported Cigarette Consumption Data
12:00 pm WRB 3-136

Physiology & Biophysics Seminar
Doryen Bubeck, PhD
Postdoctoral Fellow, Clinical Medicine
University of Oxford
Topic: Structural Studies of Membrane Proteins Using Hybrid Methods
4:00 pm SOM E-501

Aging-Cancer Research Seminar
Barbara Daly, PhD
Professor, Nursing
CWRU/ UH
Topic: Patterns of Social Support in Patients with Advanced Cancer and Family Caregivers
4:00 pm BRB 732


March 6

Hematology/ Oncology Fellows Seminar
Steven Waggoner, MD
Associate Professor & Division Chief, Gynecological Oncology
CWRU/ UH
Topic: Impact of Gynecologic Cancer Treatment and Sexual Dysfunction
8:00 am Wearn 137

Cancer Center Seminar Series/ Blood Club
Webster K. Cavanee, PhD
Director, Ludwig Institute for Cancer Research (San Diego Branch)
Director, University of California San Diego
Topic: Receptor Signaling and Therapeutic Resistance
12:00 pm BRB 105

more

For a complete listing of LRI seminars click here.


MARK YOUR CALENDARS:

UPCOMING CANCER CENTER SYMPOSIUMS

Case CCC Scientific Series
March 24
4:00 pm - 6:00 pm WRB 1-413

May 11
4:00 pm - 6:00 pm WRB 1-413

October 8
4:00 pm - 6:00 pm WRB 1-413

Family-Centered Care
March 21
Holiday Inn, Independence
Details

Signaling in Cancer
May 18-19
Wolstein Research Building (CWRU Campus)
Brochure and Registration

Ohio Collaborative Conference on Bioinformatics (OCCBIO)
June 15 - 17
CWRU campus
Details

Annual Breast Cancer Update: Highlights of the National Meetings
June 19
Marriott Cleveland East, Warrensville Heights
Details to follow

Case CCC Scientific Retreat 2009
July 10-11
Bertram Inn & Conference Center, Aurora
Details to follow

**For more information on these symposiums, please contact Christine Rhoads.


UPCOMING OUTSIDE SEMINARS

Second Annual David C. Hohn, MD Health Policy Lecture
March 30
Bruce C. Vladeck, PhD
Senior Health Policy Advisor/Executive Director
Health Sciences Advisory Services
Ernst & Young
Topic: Cancer Care as a Paradigm for Health Care Reform
5:00 pm, David C. Hohn, MD Lecture Hall, Roswell Park Cancer Institute
Details

Neuropathic Cancer Pain Symposium
April 27
Bethesda Marriott Pooks Hill
Bethesda, MD
Details

11th Annual Midwest DNA Repair Symposium
May 16-17
BSRB Auditorium, University of Michigan
Ann Arbor, MI
Abstract Deadline: May 1
Details


FUNDING OPPORTUNITY– Association for International Cancer Research (AICR)

AICR awards project grants of between one and three years to support fundamental and translational research into the causes, mechanisms, diagnosis, treatment and prevention of cancer. They will consider proposals in which a mixture of basic and clinical research is proposed. However, completely clinical applications, such as intervention studies, clinical trials or health care delivery research and many substantially clinical applications are beyond the remit of AICR.

Before submitting applications of a clinical or semi-clinical nature, potential applicants are strongly encouraged to seek advice by e-mailing a brief description of the proposed project to the Scientific Co-ordinator (matfield@aicr.org.uk).

Applications will be accepted April 1-24.

For details, please click here.


FUNDING OPPORTUNITY– Dana Foundation Program in Neuroimmunology of Brain Infections and Cancers

CWRU SOM has been invited to nominate ONE applicant for the Dana Foundation Program in Neuroimmunology of Brain Infections and Cancers. The Neuroimmunology Program was redesigned to focus on brain infections and cancers. The Foundation is inviting studies of 1) immune-based therapies for primary brain tumors and for metastases to the brain of other cancers; 2) immune responses to infections in the brain including but not limited to viral encephalitis, meningitis, cerebral malaria, and prion diseases; and 3) how immune functions are carried out and modified in the brain. The program focuses on clinical studies in humans or human tissues. Animal studies that are directly relevant to human disease but not ready for application to studies of humans or human tissues will also be considered.

This award is open to faculty tenure track researchers early in their career at the assistant professor level or early in their associate professor career. Established researchers pioneering efforts in brain infections and cancers are also eligible to apply. Postdoctoral fellows are not eligible. Projects involving collaborations with NIH intramural researchers or industry scientists are acceptable. Proposals for research that can be supported through clinical income should not be submitted.

Internal Deadline: March 2 (TODAY)

For more information, please click here. Please contact Richard J. Sohn, PhD, Richard.Sohn@case.edu., (216)368-1158 with any questions.


FUNDING OPPORTUNITY– James S. McDonnell Foundation

The Foundation offers Collaborative Activity Awards to initiate interdisciplinary discussions on problems or issues, to help launch interdisciplinary research networks, or to fund communities of researchers/practitioners dedicated to developing new methods, tools, and applications of basic research to applied problems.

In each case the focus of the collaborative activity must meet the program guidelines for one of the following program areas:
–Bridging Brain, Mind, and Behavior
–Studying Complex Systems
–Brain Cancer Research

Applications are continuously accepted for these awards.

For more information, please click here.



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

OCRP Idea Development Awards
Preproposal Deadline: March 2

OCRP Collaborative Translational Research Awards
Preproposal Deadline: March 2

PCRP Idea Development Program
Preproposal Deadline: March 3

PCRP Synergistic Idea Development Awards
Preproposal Deadline: March 3

ACS Joseph S. Silber Student Fellowship
Deadline: March 11

BCRP Postdoctoral Fellowship Awards
Proposal Deadline: March 11

BCRP Predoctoral Traineeship Awards
Proposal Deadline: March 11

BCRP Impact Awards
Preproposal Deadline: March 12

BCRP Multi-Team Awards
Preproposal Deadline: March 12

BCRP Era of Hope Scholar Awards
Pre-App/Nomination Deadline: March 12
Application Deadline: June 17

BCRP Innovator Awards
Pre-App/Nomination Deadline: March 12
Application Deadline: June 17

BCRP Impact Awards
Pre-App/Nomination Deadline: March 12
Application Deadline: June 17

BCRP Multi-team Research Awards
Pre-App/Nomination Deadline: March 12
Application Deadline: June 17

Lymphoma Society Translational Research Program
Full Applications Deadline: March 15

ASH Trainee Research Award
Deadline: March 16

James S. McDonnell Foundation 21st Century Science Initiative
Deadline: March 17

ACS Cancer Research Fellowship
Deadline: March 18

Peer Reviewed Medical Research Program (PRMRP)
Pre-Application LOI Deadline: March 19
Application Deadline: April 16

NFRP Clinical Trial Award
Pre-Application Deadline: March 24
Proposal Deadline: April 14

NFRP Investigator-Initiated Research Award
Pre-Application Deadline: March 24
Proposal Deadline: April 14

NFRP Exploration-Hypothesis Development Award
Pre-Application Deadline: March 24
Proposal Deadline: April 14

NFRP New Investigator Award
Pre-Application Deadline: March 24
Proposal Deadline: April 14

NFRP Postdoctoral Traineeship Award
Pre-Application Deadline: March 24
Proposal Deadline: April 14

NFRP Clinical Trial Award
Proposal Deadline: April 14

NFRP Investigator-Initiated Research Award
Proposal Deadline: April 14

NFRP Exploration-Hypothesis Development Award
Proposal Deadline: April 14

NFRP New Investigator Award
Proposal Deadline: April 14

NFRP Postdoctoral Traineeship Award
Proposal Deadline: April 14

Peer Reviewed Medical Research Program (PRMRP)
Application Deadline: April 16

Paul Marks Prize for Cancer Research
Nominations Deadline: April 30

BCRP Era of Hope Scholar Awards
Application Deadline: June 17

BCRP Innovator Awards
Application Deadline: June 17

BCRP Impact Awards
Application Deadline: June 17

BCRP Multi-team Research Awards
Application Deadline: June 17

NCI Short-Term Scientist Exchange Program
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Correlative Studies with Specimens from Multi-Site Trials (R21) (PA-08-133)

Testing Tobacco Products Promoted to Reduce Harm (R01) (PA-09-046)

Career Enhancement Award for Stem Cell Research (K18) (PA-09-110)

Manufacturing Processes of Medical, Dental, and Biological Technologies (SBIR [R43/R44]) PA-09-113

Manufacturing Processes of Medical, Dental, and Biological Technologies (STTR [R41/R42]) (PA-09-114)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

Janice Hassinger
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
janice.hassinger@uhhospitals.org

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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