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Case Comprehensive Cancer Center Newsletter

November 23, 2009


When Does Oversight Overstep?
Scientist - November 17, 2009
"In theory, it's a terrific thing," agreed David Kaplan of Case Western Reserve University in Ohio, who has written about the peer review system at NIH. ...


Featured Article
Independent Task Force Updates Recommendations on Breast Cancer Screening

Cancer Research Highlights
New Drug Blocks "Undruggable" Target in Cancer Cells

Treatment for Pancreatic Cancer May Target Tumor Microenvironment

Survey Finds Pain Is Common Years after Breast Cancer Surgery

Hormone Therapy Use Linked to Benign Breast Condition

Targeted Treatment Shows Promise for Older Patients with Advanced Leukemia

Potential Strategy for Treating Diffuse Large B-cell Lymphoma Found

Guest Director's Update: Dr. Eric J. (Rocky) Feuer
Modeling for Research Success

FUNDING OPPORTUNITY– NIH Fogarty International Clinical Research Fellows Program

The Fogarty International Clinical Research Scholars and Fellows (FICRS-F) Support Center at Vanderbilt is offering a one-year clinical research training experience for graduate-level US students in the health professions. This is an opportunity for highly motivated individuals to experience mentored research training at top-ranked NIH-funded research centers in developing countries.

This program is designed primarily for students meeting all of the following qualifications:
• A strong interest in and potential for a career in international health activities and/or clinical research.
• Advanced standing in a US medical, osteopathic or dental school; or enrollment in a doctoral-level program at a US school of public health, optometry, nursing, pharmacy, or veterinary medicine. Other PhD students in the health sciences may be eligible on a case-by-case basis. Applicants must have strong academic records and must be US citizens or permanent US residents. PhD candidates must have completed their Master's-level coursework. All other professional doctoral degree candidates must have completed their basic science courses and one year of clinical clerkship prior to the start of the fellowship year.
• Support of their home academic institution, including a committed mentor.

Each Fellowship will be for a one year period. The term will begin with an intensive orientation program on the NIH campus in Bethesda, MD in July. This will be followed by approximately 10+ months of intense research training at the international site.

Deadline: December 3

For more information, please click here.

MARK YOUR CALENDARS– Dr. Volker Diehl Visit/ Special Lectures

Volker Diehl, MD from the University of Koln, Germany will be visiting Taussig Cancer Institute November 30 and December 1 in advance of the ASH meeting. As you probably know, Dr Diehl is a major international figure in Hodgkin lymphoma, has directed the German Hodgkin Lymphoma Study group for more than 15 years, and has been responsible for major advances in this disease, including the International Prognostic System for HL and the BEACOPP regimen.

On December 1, Dr. Diehl will give two lectures. The first will be on Advances in the management of Hodgkin Lymphoma: the German Experience, at 8:00 am in R3-002/003 at the Cleveland Clinic. At 1:00 pm, he will present, Hodgkin Lymphoma: A Never Ending Exciting Story of Translational Research Since 1832, in R4-013 at the Cleveland Clinic.

Dr. Diehl will also be available for meetings November 30 and December 1. If anyone is interested in meeting with him during that time, please send your availability to Aimee Drury (drurya@ccf.org) and Dr. John Sweetenham (sweetej@ccf.org).


The Center for Stem Cell and Regenerative Medicine (CSCRM) has issued an RFP for pilot projects for this coming year. The goal of this pilot funding is to to provide seed money for new research ideas with priority given to projects that bring new researchers into the stem cell arena or provide funding for a "new" research area (not additional support for an existing project). Projects must have a clinical and/or commercial direction though it may be more rudimentary than for a fully developed project. The "fourth" $50K slot will be divided among the CWRU/CCF/UH tech transfer offices (TTO) to apply to stem cell projects that the TTOs recommend would significantly be assisted (in the IP/commercialization effort) by a small increment of data.

Deadline: November 23

Please click here for more information.


We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!

FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position. If you would like to nominate someone for the position, please contact Tracy Rehl (tracy.rehl@case.edu).

Click here to view the job description.


The application cycle for the NIH extramural Loan Repayment Programs (LRPs) ends December 1. The extramural LRPs often allow scientific investigators to remain in the research workforce, achieve research independence, and focus their efforts on advancing the health of the nation without having to worry about their student loan debt. The extramural LRPs include Clinical Research, Pediatric Research, Health Disparities Research, Contraception and Infertility Research, and Clinical Research for Individuals from Disadvantaged Backgrounds.

Applicants must possess a doctoral-level degree (with the exception of the Contraception and Infertility Research LRP); be a US citizen, national, or permanent resident; devote 20 hours or more per week to conducting qualified research funded by a university, nonprofit organization, or federal, state, or local government entity; and have qualified educational loan debt equal to or exceeding 20 percent of their institutional base salary.

For details, please click here.


**All events are open to anyone interested in attending

November 23

Hem/Onc Research in Progress Seminar cancelled

Pathology Research Seminar cancelled

Sequencing Data Interest Group (SDIG) Meeting
Jing Li, PhD
Assistant Professor, Electrical Engineering and Computer Science
Topic: Computational Identification of Structural Variation Using Next Generation Sequencing
2:30 pm WRB 1-413

Special Seminar: Metastatic Breast Cancer
Jianming Xu, PhD
Associate Professor, Molecular and Cellular Biology
Baylor College of Medicine
Topic: Members of the p160 SRC Family, the Crucial Players and Potential Targets in Breast Tumorigenesis and Metastasis
4:00 pm WRB 3-136

Physiology & Biophysics Seminar
Prabha Kc, PhD
Assistant Professor, Pediatrics
Topic: Role of the Hypothalamic Paraventricular Nucleus in Cardiorespiratory Control
4:00 pm SOM E501

Skeletal Research Center Seminar
Eben Alsberg, PhD
Assistant Professor, Biomedical Engineering
Topic: New Strategies and Engineered Biomaterial Systems for Tissue Regeneration
4:00 pm Millis 123

November 24

Immunology Seminar cancelled

Taussig Cancer Institute Core Curriculum Series
Robert Pelley, MD
Staff, Solid Tumor Oncology
Cleveland Clinic
Topic: Adjuvant Medical Therapy for Colon and Rectal Cancer
12:00 pm R3-002 Cleveland Clinic

November 25

Grand Rounds cancelled

November 26


November 27

Taussig Cancer Institute Grand Rounds cancelled

Cancer Center Seminar Series/ Blood Club cancelled

Hematology/ Oncology Fellows Conference cancelled


For a complete listing of LRI seminars click here.


Case CCC Scientific Series- TREC
January 28, 2010
4:00 pm - 7:00 pm WRB 1-413
Stephanie Doerner
Cheryl Thompson, PhD
Ofer Reizes, PhD
Sanjay Patel, MD


AACR Eighth Annual International Conference on Frontiers in Cancer Prevention Research
December 6-9
Hilton Americas, Houston, TX

32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium
December 10-13
Henry B. Gonzalez Convention Center, San Antonio, TX

AACR Seminar: Genetics and Biology of Brain Cancers
December 13-15
Omni San Diego Hotel, San Diego, CA

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, AZ

AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Prospects for Personalized Prevention and Therapy
January 11-14, 2010
Loews Coronado Bay Resort, Coronado, CA

AACR-JCA 8th Joint Conference on Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics
February 5-9, 2010
Hilton Waikoloa Village, Waikoloa, HI

AACR 101st Annual Meeting
April 17-21, 2010
Washington, DC


DoD BCRP Era of Hope Scholar Awards:
Application Deadline: December 2

DoD BCRP Postdoctoral Fellowship Awards:
Application Deadline: December 2

Sidney Kimmel Foundation for Cancer Research Kimmel Scholar Award
Deadline: December 2

Sidney Kimmel Foundation for Cancer Research Kimmel Translational Science Award
Deadline: December 2

DOD OCRP Ovarian Cancer Academy Dean Award
Proposal Deadline: December 2

ASCO Improving Cancer Care Grant Improving Cancer Care Grant (ICCG)
Full Application Deadline: December 3

DOD Lung Cancer Research Program Clinical Fellow Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Application Deadline: December 3

AACR-AstraZeneca Fellowship for Translational Lung Cancer Research
Deadline: December 7

AACR Basic Cancer Research Fellowships: AACR Anna D. Barker Fellowship in Basic Cancer Research and AACR-Astellas USA Foundation Fellowships in Basic Cancer Research
Deadline: December 7

AACR Clinical and Translational Cancer Research Fellowships
Deadline: December 7

AACR Judah Folkman Fellowship for Anti-Angiogenesis Research
Deadline: December 7

DOD PRCRP Synergistic Idea Awards
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Proposal Deadline: December 9

DOD PRCRP New Investigator Awards
Proposal Deadline: December 9

International Society for Stem Cell Research (ISSCR)
Deadline: January 14, 2010

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

RFA AMMENDMENT: Recovery Act Limited Competition: Building Sustainable Community-Linked Infrastructure to Enable Health Science Research (RC4) (NOT-OD-10-017)

Clarification of Eligibility as Primary Applicant for RFA-ES-09-008, Limited Competition: Continuation of Studies on Early Environmental Exposures and Human Puberty (U01) (NOT-ES-10-001)

Effectiveness Research on Smoking Cessation in Hospitalized Patients (U01) (RFA-HL-10-020)

Development, Application, and Evaluation of Prediction Models for Cancer Risk and Prognosis (R01)

Development, Application, and Evaluation of Prediction Models for Cancer Risk and Prognosis (R21) (PA-10-026)

Obesity Policy Research: Evaluation and Measures (R01) (PA-10-027)

Obesity Policy Research: Evaluation and Measures (R21) (PA-10-028)

Obesity Policy Research: Evaluation and Measures (R03) (PA-10-029)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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