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Case Comprehensive Cancer Center Newsletter

October 26, 2009


Case Western Reserve, University Hospitals License Medical Imaging Technology ...
MedCity News - October 26, 2009
... formerly on the biomedical engineering faculty at Case and now part of the biomedical engineering faculty at Duke University, and Andrew Rollins, ...

Holistic Approach Vital to Victory
Delphos Herald - Mike Ford - October 26, 2009
These treatments are offered alongside conventional treatment at the Cleveland Clinic Taussig Cancer Institute, as well as Cancer Treatment Centers of ...

MARK YOUR CALENDARS– Case CCC Scientific Series

The next installment of the Case CCC Scientific Series is scheduled for Thursday, November 5 from 4-7 pm in Wolstein Auditorium (WRB 1-413). Drs. Timothy Nilsen, Eain Murphy and Saba Valadkhan are scheduled to present on RNA Microanalysis technology and how it relates to cancer research. A small reception will take place following the presentations. Everyone in the cancer community is encouraged to attend.

MARK YOUR CALENDARS– Cancer Prevention and Control Meeting

A Cancer Prevention and Control meeting has been scheduled for October 30 from 12:30 – 2:00 pm in Wearn 137.

The purpose of the meeting is to bring people together to discuss community-based and community-participatory cancer prevention research:

  • ongoing projects, programs and research
  • planned projects
  • funding opportunities
  • interest and momentum in going after a grant like the Community Program Network RFA.

Anyone with an interest in this topic is encouraged to attend. Please RSVP to gillian.irwin@case.edu. If you are unable to attend, but would like to participate in the Community Program Network RFA, please send a description of your area of interest to gillian.irwin@case.edu.


The American Association for Cancer Research (AACR) is accepting applications for the following funding opportunities:

AACR-Colorectal Cancer Coalition Fellows Grant, in memory of Lisa Dubow:
Research projects are restricted to translational or clinical cancer research that has an ultimate goal of developing or improving therapeutic interventions for patients with metastatic colorectal cancer.
Deadline: November 18

AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research:
Research projects are restricted to translational pancreatic cancer research that includes the use of human tissue and has implications for therapeutic application and individualized medicine. Proposed research must have implications for individualized cancer treatment and must make use of human biopsies or samples, such as needle biopsies or circulating cancer cells. In vivo primary tumor explants meet these criteria, but xenografts from established cell lines do not.
Deadline: November 18

FUNDING OPPORTUNITY– DOD Breast Cancer Research Program (BCRP)

DoD BCRP Era of Hope Scholar Awards:
The Era of Hope Scholar Award supports individuals who have high potential for innovation in breast cancer research early in their careers. Nominees for this award should be exceptionally talented, early-career scientists who have demonstrated that they are the "best and brightest" in their field(s) through extraordinary creativity, vision, and productivity. They also should exhibit strong potential for leadership in the breast cancer research community and be able to articulate a vision for the eradication of breast cancer. Experience in breast cancer research is not required; however, the application should focus on breast cancer research, and the PI must commit at least 50% of his/her full-time professional effort during the award period to breast cancer research. Principal Investigators (PIs) must be independent, non-mentored investigators within 6 years of their last mentored position.

Pre-Application Deadline: November 18
Application Deadline: December 2

DoD BCRP Postdoctoral Fellowship Awards:
Postdoctoral Fellowship Awards support exceptionally talented recent medical or other doctoral graduates in their pursuit of innovative, high-impact breast cancer research during their postdoctoral training and allows them to obtain the necessary experience for an independent career at the forefront of breast cancer research. The postdoctoral trainee is considered the Principal Investigator (PI) and, as such, should write the project narrative with appropriate direction from the mentor. While the PI is not required to have previous experience in breast cancer research, this application must focus on breast cancer research. Applications must provide evidence of the PI's potential for success in becoming an independent breast cancer researcher based on his/her qualifications, characteristics, achievements, and letters of recommendations. The mentor (or co-mentor, if applicable) must possess the appropriate expertise and experience in breast cancer, to include peer reviewed breast cancer funding and publications, and clearly demonstrate a commitment to guiding the PI's research and training. As of the application submission deadline, the PI must have been in the laboratory in which this research is to be performed for no more than 2 years, and he/she must have a total of less than 4 years of postdoctoral research experience (excluding clinical residency or fellowship training).

Pre-Application Deadline: November 18
Application Deadline: December 2

CALL FOR ABSTRACTS– International Society for Stem Cell Research (ISSCR)

The International Society for Stem Cell Research (ISSCR) is accepting abstracts for the ISSCR Annual Meeting, June 16-19, 2010 in San Francisco, CA. This meeting has become the preeminent international stem cell meeting of the foremost stem cell professionals from public, private, academic and government settings. It provides a forum to promote and foster the exchange of research, featuring leading discoveries of the year and serving as a catalyst for inspired stem cell research around the world.

Deadline: January 14, 2010

Each abstract must be submitted as an oral or a poster presentation. For details, please click here.


Featured Article
Better Options for Children with Difficult-to-Treat Leukemia

Cancer Research Highlights
Minimally Invasive Prostate Cancer Surgery Shows Benefits, Shortcomings

Liver Cancer Study Finds Potential Marker for Treatment

Gene Mutation Linked to Aggressive Childhood Cancer

Primary and Metastatic Tumors from Same Patient Sequenced

Prostate Tumor Microenvironment Found to Change Immune Cell's Function

Guest Director's Update: Dr. James H. Doroshow
The NExT Steps in Drug Development at NCI


We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!

CALL FOR NOMINATIONS– AACR Future Leaders in Translational Research Special Symposium

The AACR Associate Member Council seeks institutional nominations of outstanding young investigators as speakers for the Future Leaders in Translational Research Special Symposium, to be held during the AACR 101st Annual Meeting, April 17-21, 2010, in Washington, DC.

Selected speakers will be invited to present a 25 minute platform presentation and will be introduced by a prominent senior researcher within their field. Selected candidates will be considered Invited Speakers at the Annual Meeting, receiving complimentary registration and reimbursement of eligible expenses related to meeting attendance.

Institutional nominations will be accepted from any cancer center director, dean, or other leader of any institution involved in cancer research, cancer medicine, or cancer-related biomedical science; such institutions include those within academia, industry, and government, anywhere in the world. Each institution may submit up to two nominees, who may be graduate students, medical students or residents, clinical fellows, or postdoctoral fellows. Junior faculty are not eligible for nomination, including trainees expected to advance to junior faculty status prior to the Symposium.

Please send your nominations to Gillian Irwin Todd (gillian.irwin@case.edu) ASAP.

Nomination Deadline: October 30

For more information, please click here.


The application cycle for the NIH extramural Loan Repayment Programs (LRPs) ends December 1. The extramural LRPs often allow scientific investigators to remain in the research workforce, achieve research independence, and focus their efforts on advancing the health of the nation without having to worry about their student loan debt. The extramural LRPs include Clinical Research, Pediatric Research, Health Disparities Research, Contraception and Infertility Research, and Clinical Research for Individuals from Disadvantaged Backgrounds.

Applicants must possess a doctoral-level degree (with the exception of the Contraception and Infertility Research LRP); be a US citizen, national, or permanent resident; devote 20 hours or more per week to conducting qualified research funded by a university, nonprofit organization, or federal, state, or local government entity; and have qualified educational loan debt equal to or exceeding 20 percent of their institutional base salary.

For details, please click here.

CALL FOR NOMINATIONS– Doris Duke Charitable Foundation Clinical Scientist Development Award

The Doris Duke Charitable Foundation is accepting nominations for the Clinical Scientist Development Award. This award provides grants to junior physician-scientists to facilitate their transition to independent clinical research careers. Each U.S. accredited, degree-granting institution, "which would encompass for that institution all affiliated graduate schools, related hospitals and research institutes", may nominate up to two candidates.

Nomination Deadline: November 17
Proposal Deadline: December 22

For more information, please click here.

FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position.

Click here to view the job description.


**All events are open to anyone interested in attending

October 26

Hem/Onc Research in Progress Seminar
Greg Li, PhD
Research Associate, Bunting Lab, Div. of Hem/Onc
Topic: STAT5 Requires the N-domain for Suppression of miR15/16, Induction of bcl-2, and Survival Signaling in Myeloproliferative Disease
12:00 pm WRB 2-136

Pathology Research Seminar
Bruce Mayer, PhD
Professor, Genetics and Developmental Biology
University of Connecticut
Topic: SH2 Profiling: a Global View of Phosphotyrosine Signaling in Normal Cells and in Cancer
12:00 pm WRB 1-413

Neurosciences Thesis Defense
Amber Kerstetter-Fogle
PhD Candidate, Neurosciences
Topic: Role of Chemokines in Regulating Oligodendrocyte Development, Astrogliosis, and Demyelinating Diseases
1:00 pm SOM E646

Sequencing Data Interest Group (SDIG) Meeting
David Serre, PhD
Assistant Staff, Genomic Medicine Institute
CWRU/ Cleveland Clinic
Topic: Characterization of Genome-Wide Patterns of DNA Methylation by MBD Precipitation-Genome Sequencing
2:30 pm WRB 1-413

Special Cancer Center Seminar Series/ Blood Club Seminar
Steven Devine, MD
Director, Blood and Marrow Transplant Program
Ohio State University
Topic: Improving Allogeneic Hematopoietic Cell Transplantation in AML
4:00 pm WRB 2-136

Skeletal Research Center Seminar
Max Teets
Graduate Student, Skeletal Research Center
Topic: Are Adipose-Derived Stromal Cells a Subpopulation of Pericytes?
4:00 pm Millis 123

October 27

Breast Cancer Spotlight Series
William Muller, MD
Professor, Biochemistry
McGill University
Topic: Oncogene-Mediated Signaling in Transgenic Mouse Models of Human Breast Cancer
12:00 pm SOM W331

Immunology Seminar
Gareth Hardy
Research Associate, Pathology
Topic: Interference Overload: Dysregulation of Type-1 Interferon in HIV-1 Infection
12:00 pm WRB 1-413

Taussig Cancer Institute Core Curriculum Series
David Adelstein, MD
Professor, Solid Tumor Oncology
CWRU/ Cleveland Clinic
Topic: Head and Neck Cancer
12:00 pm R3-002 Cleveland Clinic

October 28

Grand Rounds
Kristine Zanotti, MD
Assistant Professor, Gynecologic Oncology
Topic: Challenges in the Management of Recurrent Cervical Cancer
8:00 am Lerner Tower B-151

October 29

Taussig Cancer Institute Core Curriculum Series
Anjali Advani, MD
Assistant Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: Acute Lymphocytic Leukemia
12:00 pm R3-002 Cleveland Clinic

Special Seminar
Stephen Sagar, BSc(Hons) MB BS MRCP FRCR DABR FRCP(C)
Associate Professor, Oncology- Radiation Oncology
McMaster University
Gary Deng, MD, PhD
Associate Attending, Associate Member
Memorial Sloan-Kettering Cancer Center
Topic: The Purpose of Integrative Oncology in a Comprehensive Cancer Center
4:00 pm Frohring Auditorium – BRB 105

October 30

Cancer Center Seminar Series/ Blood Club cancelled

Hematology/ Oncology Fellows Conference
Lalitha Nayak, MD
Fellow, Div. of Hem/Onc
Evi Stavrou, MD
Fellow, Hem/Onc
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Joan Schiller, MD
Professor, Internal Medicine- Hem/Onc
UT Southwestern
Topic: The Changing Face of Non-Small Cell Lung Cancer
8:00 am R3/002-003A Cleveland Clinic

Prevention and Control Meeting
12:30 - 2:00 pm Wearn 137

Neurosciences Seminar
Anne West, MD, PhD
Assistant Professor, Neurobiology
Duke University
Topic: Roles of the Methyl-DNA Binding Transcriptional Regulator MeCP2 in the Development and Function of Brain Networks that Mediate Monoamine-Regulated Behaviors
12:10 pm SOM E501


For a complete listing of LRI seminars click here.


Case CCC Scientific Series- RNA Microanalysis
November 5
4:00 pm - 7:00 pm WRB 1-413
Timothy Nilsen, PhD
Eain Murphy, PhD
Saba Valadkhan, PhD

Case CCC Scientific Series- TREC
January 28, 2010
4:00 pm - 7:00 pm WRB 1-413
Stephanie Doerner
Cheryl Thompson, PhD
Ofer Reizes, PhD
Sanjay Patel, MD


AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
November 15-19
John B. Hynes Veterans Memorial Convention Center, Boston, MA

AACR Seminar: Frontiers in Cancer Prevention Research
December 6-9
Houston, TX

AACR Eighth Annual International Conference on Frontiers in Cancer Prevention Research
December 6-9
Hilton Americas, Houston, TX

32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium
December 10-13
Henry B. Gonzalez Convention Center, San Antonio, TX

AACR Seminar: Genetics and Biology of Brain Cancers
December 13-15
Omni San Diego Hotel, San Diego, CA

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, AZ

AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Prospects for Personalized Prevention and Therapy
January 11-14, 2010
Loews Coronado Bay Resort, Coronado, CA

AACR-JCA 8th Joint Conference on Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics
February 5-9, 2010
Hilton Waikoloa Village, Waikoloa, HI

AACR 101st Annual Meeting
April 17-21, 2010
Washington, DC


NIH Director's New Innovator Awards
Deadline: October 27

Pancreatic Cancer Action Network-AACR Career Development Awards
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Research Fellowship
Application Deadline: October 28

DOD BCRP Concept Award
Pre-Application Deadline: October 29
Proposal Deadline: November 12

ED Thomas Post Doctoral Fellowship 2009
Deadline: November 2

DOD BCRP Concept Award
Proposal Deadline: November 12

Komen Postdoctoral Fellowship Research (PDF) Grants
Full Application Deadline: November 17

Komen Post-Baccalaureate Training in Disparities Research (PBT-DR) Grants
Full Application Deadline: November 17

DOD Lung Cancer Research Program Clinical Fellow Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

Sidney Kimmel Foundation for Cancer Research Kimmel Scholar Award
Deadline: December 2

Sidney Kimmel Foundation for Cancer Research Kimmel Translational Science Award
Deadline: December 2

DOD OCRP Ovarian Cancer Academy Dean Award
Proposal Deadline: December 2

ASCO Improving Cancer Care Grant Improving Cancer Care Grant (ICCG)
Full Application Deadline: December 3

DOD Lung Cancer Research Program Clinical Fellow Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Application Deadline: December 3

DOD PRCRP Synergistic Idea Awards
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Proposal Deadline: December 9

DOD PRCRP New Investigator Awards
Proposal Deadline: December 9

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Notice on Development of Data Sharing Policy for Sequence and Related Genomic Data

Request for Information (RFI): Candidate Biomarkers of Hepatocellular Carcinoma for Validation in a Unique Human Cohort (NOT-CA-10-004)

Environmental Influences during Windows of Susceptibility in Breast Cancer Risk (U01) (RFA-ES-09-009)

Coordinating Center for the Breast Cancer and the Environment Research Program (U01) (RFA-ES-09-010)

Roadmap Transformative Research Projects Program (R01) RFA-RM-09-022

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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